Improved 1000-m running performance and pacing strategy with caffeine and placebo effect: a balanced placebo design study

Purpose: To investigate the placebo effect of caffeine on pacing strategy and performance over 1000-m running time-trials using a balanced placebo design. Methods: Eleven well-trained male middle-distance athletes performed seven 1000-m time-trials (one familiarisation, two baseline and four experimental). Experimental trials consisted of the administration of four treatments: informed caffeine/received caffeine (CC), informed caffeine/received placebo (CP), informed placebo/received caffeine (PC), and informed placebo/received placebo (PP). Treatments were randomized. Split times were recorded at 200-, 400-, 600-, 800- and 1000-m and peak heart rate (HRpeak) and rating of perceived exertion (RPE) were recorded at the completion of the trial. Results: Relative to baseline, participants ran faster during CC (d = 0.42) and CP (d = 0.43). These changes were associated with an increased pace during the first half of the trial. No differences were shown in pacing or performance between baseline and the PC (d = 0.21) and open administration of placebo (d = 0.10). No differences were reported between treatments for HRpeak (η2 = 0.084) and RPE (η2 = 0.009). Conclusions: Our results indicate that the effect of believing to have ingested caffeine improved performance to the same magnitude as actually receiving caffeine. These improvements were associated with an increase in pace during the first half of the time-trial

Lattice and spin excitations in multiferroic h-YMnO3

We used Raman and terahertz spectroscopies to investigate lattice and magnetic excitations and their cross-coupling in the hexagonal YMnO3 multiferroic. Two phonon modes are strongly affected by the magnetic order. Magnon excitations have been identified thanks to comparison with neutron measurements and spin wave calculations but no electromagnon has been observed. In addition, we evidenced two additional Raman active peaks. We have compared this observation with the anti-crossing between magnon and acoustic phonon branches measured by neutron. These optical measurements underly the unusual strong spin-phonon coupling

Elastic Tensor of YNi_2B_2C

The complete elastic tensor of YNi_2B_2C was determined by application of the resonant ultrasound spectroscopy technique to a single-crystal sample. Elastic constants were found to be in good agreement with partial results obtained from `time-of-flight' measurements performed on samples cut from the same ingot. From the measured constants, the bulk modulus and Debye temperature are calculated.Comment: 5 pages, 3 figure

Periodic mass loss episodes due to an oscillation mode with variable amplitude in the hot supergiant HD50064

We aim to interpret the photometric and spectroscopic variability of the luminous blue variable supergiant HD\,50064 ($V=8.21$).CoRoT space photometry and follow-up high-resolution spectroscopy, with a time base of 137\,d and 169\,d, respectively, was gathered, analysed and interpreted using standard time series analysis and light curve modelling methods as well as spectral line diagnostics.The space photometry reveals one period of 37\,d, which undergoes a sudden amplitude change with a factor 1.6. The pulsation period is confirmed in the spectroscopy, which additionally reveals metal line radial velocity values differing by $\sim 30\,$km\,s$^{-1}$ depending on the spectral line and on the epoch. We estimate \teff$\sim$13\,500\,K, \logg$\sim$1.5 from the equivalent width of Si lines. The Balmer lines reveal that the star undergoes episodes of changing mass loss on a time scale similar to the changes in the photometric and spectroscopic variability, with an average value of $\log\dot{\rm M}\simeq-5$ (in M$_\odot$\,yr$^{-1}$). We tentatively interpret the 37\,d period as due to a strange mode oscillation.Comment: 4 pages, accepted for publication in Astronomy & Astrophysics Letter

CoRoT observations of O stars: diverse origins of variability

Six O-type stars were observed continuously by the CoRoT satellite during a 34.3-day run. The unprecedented quality of the data allows us to detect even low-amplitude stellar pulsations in some of these stars (HD 46202 and the binaries HD 46149 and Plaskett's star). These cover both opacity-driven modes and solar-like stochastic oscillations, both of importance to the asteroseismological modelling of O stars. Additional effects can be seen in the CoRoT light curves, such as binarity and rotational modulation. Some of the hottest O-type stars (HD 46223, HD 46150 and HD 46966) are dominated by the presence of red-noise: we speculate that this is related to a sub-surface convection zone.Comment: 5 pages, 3 figures, conference paper. To be published in "Four decades of Research on Massive Stars", Astronomical Society of the Pacific. Eds. C. Robert, N. St-Louis and L. Drisse

Plaskett's Star: Analysis of the CoRoT photometric data

The SRa02 of the CoRoT space mission for Asteroseismology was partly devoted to stars belonging to the Mon OB2 association. An intense monitoring was performed on Plaskett's Star (HD47129) and the unprecedented quality of the light curve allows us to shed new light on this very massive, non-eclipsing binary system. We particularly aimed at detecting periodic variability which might be associated with pulsations or interactions between both components. We also searched for variations related to the orbital cycle which could help to constrain the inclination and the morphology of the binary system. A Fourier-based prewhitening and a multiperiodic fitting procedure were applied to analyse the time series and extract the frequencies of variations. We describe the noise properties to tentatively define an appropriate significance criterion, to only point out the peaks at a certain significance level. We also detect the variations related to the orbital motion and study them by using the NIGHTFALL program. The periodogram exhibits a majority of peaks at low frequencies. Among these peaks, we highlight a list of about 43 values, including notably two different sets of harmonic frequencies whose fundamental peaks are located at about 0.07 and 0.82d-1. The former represents the orbital frequency of the binary system whilst the latter could probably be associated with non-radial pulsations. The study of the 0.07d-1 variations reveals the presence of a hot spot most probably situated on the primary star and facing the secondary. The investigation of this unique dataset constitutes a further step in the understanding of Plaskett's Star. These results provide a first basis for future seismic modelling. The existence of a hot region between both components renders the determination of the inclination ambiguous.Comment: Accepted in A&A, 13 pages, 7 figures, 2 table

Platypnea-orthodeoxia associated with a fenestrated atrial septal aneurysm: Case Report

BACKGROUND: Platypnea-orthodeoxia describes the condition of combined dyspnea and hypoxia respectively, whilst in the upright position, which improves in the recumbent position. CASE REPORT: We present a case of platypnea-orthodeoxia due to a fenestrated atrial septal defect associated with an atrial septal aneurysm. Due to the fenestrated nature of the atrial septal defect, surgical rather than percutaneous correction was performed. CONCLUSION: A high index of suspicion is required to diagnose the syndrome of platypnea-orthodeoxia. Careful echocardiographic evaluation is required to identify the syndrome, and to determine suitability for percutaneous repair

Stents in pediatric and adult congenital cardiac catheterization in France in 2013

Stents have contributed to the development of the interventional catheterization for congenital heart diseases (CHD). The aim of this study was to describe indications, results and adverse events in current practice.MethodsThe participation to this study was proposed to all catheterization laboratories specialized in CHD in France (M3C network). All cases with stents implantation in 2013 in pediatric and adult CHD were retrospectively included. Adverse events were assessed using the Bergersen classification.Results174 stents were implanted during 132 procedures in 127 patients by 6 main operators in 9 centers. Patients were aged 15.7±15.1years old (min 5day-old - max 70years old). Sixteen types of procedures were identified. Main indications were transcatheter pulmonary valve replacement (29 patients, 23.0%), pulmonary artery branches angioplasty (34 patients, 27.0%), aortic (re)coarctation stenting (37 patients, 29.4%) and ductus arteriosus stenting (11 patients, 8.7%). 18 patients (14.3%) were under one y.o and 35 (27.8%) were over 18y.o. Main pathologies were tetralogy of Fallot and variants (ACC-CHD 8.3, n=45, 35.7%), and aortic coarctation (ACC-CHD 9.2, n=36, 28.6%). More than 1 stent was implanted in 32 procedures (24.4%, max. 5 stents). Main stents implanted were the CP stent (33.0%), EV3 LD max (22.0%), Valeo (16.2%) and valved stents (15.0%). 98.5% procedures were considered as successful. Serious adverse events were observed in 12.9%. After multivariate adjustment, only procedure type was related to the risk of total adverse events (OR: 3.0, 95%CI 1.1–7.9) but not to stent related adverse events. Age, weight, center, operator, type of stents, stent diameter, genetic disorder and type of CHD were not significantly related to the risk of adverse events.ConclusionStents are used in various CHD catheterization procedures, from infancy to adult age. Adverse events rate is significant and seems related to the type of procedure