Nearly 5m antidepressants, anti-anxiety drugs dispensed up to August 2021.

Figures collected by Health Market Research Ireland for the Irish Pharmacy Union reveal pharmacists are dispensing a growing number of antidepressants, mood stabilisers, and tranquillisers since the onset of Covid-19...

Nebulized Tranexamic Acid in Secondary Post-Tonsillectomy Hemorrhage: Case Series and Review of the Literature

Introduction: Post-tonsillectomy hemorrhage is a serious postoperative complication, and its acute management can present a challenge for the emergency provider. Although various strategies have been proposed, guidance on the best approach for management of this condition in the emergency department (ED) setting remains limited. Anecdotal reports of the use of nebulized tranexamic acid (TXA) for management of tonsillar bleeding have emerged over the past two years. Two recently published case reports describe the successful use of nebulized TXA for stabilization of post-tonsillectomy hemorrhage in an adult and a pediatric patient.Case Series: Eight patients who presented to our ED with secondary post-tonsillectomy hemorrhage received nebulized TXA for hemostatic management. The most common TXA dose used was 500 milligrams, and all but one patient received a single dose of the medication in the ED. Hemostatic benefit was observed in six patients, with complete bleeding cessation observed in five cases. Interventions prior to nebulized TXA administration were attempted in three of the six patients and included ice water gargle, direct pressure with TXA-soaked gauze, and nebulized racemic epinephrine. All but one of the patients were taken to the operating room for definitive management after initial stabilization in the ED. Conclusion: Nebulized TXA may offer a hemostatic benefit and aid in stabilization of tonsillectomy hemorrhage in the acute care setting, prior to definitive surgical intervention.  Consideration of general principles of nebulization and aerosol particle size may be an important factor for drug delivery to the target tissue site

Assisting Blind and Visually Impaired Swimmers (semester?), IPRO 310: Blind Swimmers IPRO 310 Final Report F07

This objective of this IPRO is to develop devices to aid visually impaired persons swim. The team has chosen to work on two separate devices to accomplish this task. One approach is to use a passive device, which is located in the pool, to guide the swimmers through the lane. A picture of the latest version of the device is pictured below in figure 1 with several key features identified.Deliverables for IPRO 310: Assisting Blind and Visually Impaired Swimmers for the Fall 2007 semeste

Assisting Blind and Visually Impaired Swimmers (semester?), IPRO 310: Blind Swimmers IPRO 310 Brochure F07

This objective of this IPRO is to develop devices to aid visually impaired persons swim. The team has chosen to work on two separate devices to accomplish this task. One approach is to use a passive device, which is located in the pool, to guide the swimmers through the lane. A picture of the latest version of the device is pictured below in figure 1 with several key features identified.Deliverables for IPRO 310: Assisting Blind and Visually Impaired Swimmers for the Fall 2007 semeste

FOURIER-JACOBI TYPE SPHERICAL FUNCTIONS ON Sp(2,R)S_p(2,\mathbf{R}) ; THE CASE OF PJP_J-PRINCIPAL SERIES AND DISCRETE SERIES (Automorphic Forms and Number Theory)

Gilles de la Tourette Syndrome (GTS) is characterized by the presence of multiple motor and phonic tics with a fluctuating course of intensity, frequency, and severity. Up to 90% of patients with GTS present with comorbid conditions, most commonly attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive disorder (OCD), thus providing an excellent model for the exploration of shared etiology across disorders. TS-EUROTRAIN (FP7-PEOPLE-2012-ITN, Grant Agr.No. 316978) is a Marie Curie Initial Training Network (http://ts-eurotrain.eu) that aims to elucidate the complex etiology of the onset and clinical course of GTS, investigate the neurobiological underpinnings of GTS and related disorders, translate research findings into clinical applications, and establish a pan-European infrastructure for the study of GTS. This includes the challenges of (i) assembling a large genetic database for the evaluation of the genetic architecture with high statistical power; (ii) exploring the role of gene-environment interactions including the effects of epigenetic phenomena; (iii) employing endophenotype-based approaches to understand the shared etiology between GTS, OCD, and ADHD; (iv) establishing a developmental animal model for GTS; (v) gaining new insights into the neurobiological mechanisms of GTS via cross-sectional and longitudinal neuroimaging studies; and (vi) partaking in outreach activities including the dissemination of scientific knowledge about GTS to the public. Fifteen partners from academia and industry and 12 PhD candidates pursue the project. Here, we aim to share the design of an interdisciplinary project, showcasing the potential of large-scale collaborative efforts in the field of GTS. Our ultimate aims are to elucidate the complex etiology and neurobiological underpinnings of GTS, translate research findings into clinical applications, and establish Pan-European infrastructure for the study of GTS and associated disorders