Professionnalisation dans l'enseignement supérieur : quelles logiques territoriales ?

En ligne sur : http://www.cereq.fr/index.php/content/download/562/8279/file/netdoc59.pdfNational audienceLa question posée dans cette recherche est celle de l'existence d'une ou de plusieurs stratégies dans la construction de l'offre de formation professionnalisante dans l'enseignement supérieur ; la focale est placée sur l'étude des licences professionnelles, masters et doctorats. La construction de l'offre de formation y est abordée comme le résultat de coordinations complexes entre quatre catégories d'acteurs qui contribuent à cette construction : les organismes de formation, les entreprises, l'État et les collectivités territoriales.Les résultats de cette recherche reposent sur une série d'enquêtes menées dans cinq régions (Aquitaine,Bretagne, Poitou-Charentes, Provence-Alpes-Côte d'Azur et Rhône-Alpes) qui présentent des caractéristiques différentes sur plusieurs dimensions : poids des formations professionnalisantes dans l'ensemble des formations supérieures ; dynamique de professionnalisation observée au sein des universités ; structure par niveau de diplôme des formations professionnalisantes délivrées ; répartition territoriale des formations au sein de chaque région. Ils montrent que, dans leur grande majorité, les coordinations qui président à l'ouverture d'un diplôme professionnalisant dépendent d'un ensemble de variables : nature de la formation et de l'organisme qui en est porteur, comportement des demandeurs, caractéristiques des entreprises concernées par les qualifications des formés. Elles varient d'un territoire à l'autre en fonction des acteurs en présence et de la nature de leurs relations. Ainsi, l'offre de formation résulte-t-elle de constructions hybrides situées selon les territoires. On constate que les secteurs disciplinaires sont impactés différemment par la professionnalisation et que la création des licences professionnelles est particulièrement forte dans les sites universitaires secondaires. Par ailleurs, la conception de diplômes professionnalisant émane de l'initiative individuelle ou de celle d'une petite équipe en dehors d'une stratégie d'ensemble clairement affirmée. Il en découle un manque de lisibilité de l'offre de formation, que ce soit au niveau de la licence ou du master, tant pour les étudiants que pour les milieux économiques. Enfin, bien qu'ouvertes à tous les publics, les licences professionnelles tendent à professionnaliser un public qui l'est déjà. Elles permettent également d'obtenir des rémunérations plus élevées qu'avec une licence générale

Selective separation and preconcentration of Th(IV) using organo-functionalized, hierarchically porous silica monoliths

The potential application of thorium (Th) as nuclear fuel, as well as the environmental and public health concerns associated with it, promotes the development of economic and sustainable materials for the separation and removal of Th(IV) from minerals and environmental samples. In this work, centimeter-size, porous silica monoliths exhibiting hierarchical macroporosity-mesoporosity -and a robust silica skeleton were prepared using a sol−gel process combined with post-synthetic hydrothermal treatment in ammonium hydroxide. Upon functionalization with diglycolamide (DGA), the monolithic silica was used as a column-type fixed bed sorbent for continuous flow extraction. An enhanced Th(IV) uptake from aqueous solution was achieved with high enrichment factor and selectivity in the presence of competitive ions such as rare earth elements (REEs) and uranium (U). Systematic mechanistic studies show that the hierarchical pore system is crucial for enhanced adsorption kinetics and capacity. Two mineral leachates were used to assess the performances of the hybrid material, and despite the complex ion matrix and high ionic composition, the sorbent shows highly efficient recovery of Th(IV). The material was able to undergo 10 extraction-stripping-regeneration cycles, which bode well for potential industrial applications

Evaluating how agent methodologies support the specification of the normative environment through the development process

[EN] Due to the increase in collaborative work and the decentralization of processes in many domains, there is an expanding demand for large-scale, flexible and adaptive software systems to support the interactions of people and institutions distributed in heterogeneous environments. Commonly, these software applications should follow specific regulations meaning the actors using them are bound by rights, duties and restrictions. Since this normative environment determines the final design of the software system, it should be considered as an important issue during the design of the system. Some agent-oriented software engineering methodologies deal with the development of normative systems (systems that have a normative environment) by integrating the analysis of the normative environment of a system in the development process. This paper analyses to what extent these methodologies support the analysis and formalisation of the normative environment and highlights some open issues of the topic.This work is partially supported by the PROMETEOII/2013/019, TIN2012-36586-C03-01, FP7-29493, TIN2011-27652-C03-00, CSD2007-00022 projects, and the CASES project within the 7th European Community Framework Program under the grant agreement No 294931.Garcia Marques, ME.; Miles, S.; Luck, M.; Giret Boggino, AS. (2014). Evaluating how agent methodologies support the specification of the normative environment through the development process. Autonomous Agents and Multi-Agent Systems. 1-20. https://doi.org/10.1007/s10458-014-9275-zS120Cossentino, M., Hilaire, V., Molesini, A., & Seidita, V. (Eds.). (2014). Handbook on agent-oriented design processes (Vol. VIII, 569 p. 508 illus.). Berlin: Springer.Akbari, O. (2010). A survey of agent-oriented software engineering paradigm: Towards its industrial acceptance. Journal of Computer Engineering Research, 1, 14–28.Argente, E., Botti, V., Carrascosa, C., Giret, A., Julian, V., & Rebollo, M. (2011). An abstract architecture for virtual organizations: The THOMAS approach. Knowledge and Information Systems, 29(2), 379–403.Argente, E., Botti, V., & Julian, V. (2009). GORMAS: An organizational-oriented methodological guideline for open MAS. In Proceedings of AOSE’09 (pp. 440–449).Argente, E., Botti, V., & Julian, V. (2009). Organizational-oriented methodological guidelines for designing virtual organizations. In Distributed computing, artificial intelligence, bioinformatics, soft computing, and ambient assisted living. Lecture Notes in Computer Science (Vol. 5518, pp. 154–162).Boella, G., Pigozzi, G., & van der Torre, L. (2009). Normative systems in computer science—Ten guidelines for normative multiagent systems. In G. Boella, P. Noriega, G. Pigozzi, & H. Verhagen (Eds.), Normative multi-agent systems, number 09121 in Dagstuhl seminar proceedings.Boella, G., Torre, L., & Verhagen, H. (2006). Introduction to normative multiagent systems. Computational and Mathematical Organization Theory, 12(2–3), 71–79.Bogdanovych, A., Esteva, M., Simoff, S., Sierra, C., & Berger, H. (2008). A methodology for developing multiagent systems as 3d electronic institutions. In M. Luck & L. Padgham (Eds.), Agent-Oriented Software Engineering VIII (Vol. 4951, pp. 103–117). Lecture Notes in Computer Science. Berlin: Springer.Boissier, O., Padget, J., Dignum, V., Lindemann, G., Matson, E., Ossowski, S., Sichman, J., & Vazquez-Salceda, J. (2006). Coordination, organizations, institutions and norms in multi-agent systems. LNCS (LNAI) (Vol. 3913).Bordini, R. H., Fisher, M., Visser, W., & Wooldridge, M. (2006). Verifying multi-agent programs by model checking. In Autonomous agents and multi-agent systems (Vol. 12, pp. 239–256). Hingham, MA: Kluwer Academic Publishers.Botti, V., Garrido, A., Giret, A., & Noriega, P. (2011). The role of MAS as a decision support tool in a water-rights market. In Post-proceedings workshops AAMAS2011 (Vol. 7068, pp. 35–49). Berlin: Springer.Breaux, T. (2009). Exercising due diligence in legal requirements acquisition: A tool-supported, frame-based approach. In Proceedings of the IEEE international requirements engineering conference (pp. 225–230).Breaux, T. D., & Baumer, D. L. (2011). Legally reasonable security requirements: A 10-year ftc retrospective. Computers and Security, 30(4), 178–193.Breaux, T. D., Vail, M. W., & Anton, A. I. (2006). Towards regulatory compliance: Extracting rights and obligations to align requirements with regulations. In Proceedings of the 14th IEEE international requirements engineering conference, RE ’06 (pp. 46–55). Washington, DC: IEEE Computer Society.Bresciani, P., Perini, A., Giorgini, P., Giunchiglia, F., & Mylopoulos, J. (2004). Tropos: An agent-oriented software development methodology. Autonomous Agents and Multi-Agent Systems, 8(3), 203–236.Cardoso, H. L., & Oliveira, E. (2008). A contract model for electronic institutions. In COIN’07: Proceedings of the 2007 international conference on Coordination, organizations, institutions, and norms in agent systems III (pp. 27–40).Castor, A., Pinto, R. C., Silva, C. T. L. L., & Castro, J. (2004). Towards requirement traceability in tropos. In WER (pp. 189–200).Chopra, A., Dalpiaz, F., Giorgini, P., & Mylopoulos, J. (2009). Modeling and reasoning about service-oriented applications via goals and commitments. ICST conference on digital business.Cliffe, O., Vos, M., & Padget, J. (2006). Specifying and analysing agent-based social institutions using answer set programming. In O. Boissier, J. Padget, V. Dignum, G. Lindemann, E. Matson, S. Ossowski, J. Sichman, & J. Vázquez-Salceda (Eds.), Coordination, organizations, institutions, and norms in multi-agent systems. Lecture Notes in Computer Science (Vol. 3913, pp. 99–113). Springer. Berlin.Criado, N., Argente, E., Garrido, A., Gimeno, J. A., Igual, F., Botti, V., Noriega, P., & Giret, A. (2011). Norm enforceability in Electronic Institutions? In Coordination, organizations, institutions, and norms in agent systems VI (Vol. 6541, pp. 250–267). Springer.Dellarocas, C., & Klein, M. (2001). Contractual agent societies. In R. Conte & C. Dellarocas (Eds.), Social order in multiagent systems (Vol. 2, pp. 113–133)., Multiagent Systems, Artificial Societies, and Simulated Organizations New York: Springer.DeLoach, S. A. (2008). Developing a multiagent conference management system using the o-mase process framework. In Proceedings of the international conference on agent-oriented software engineering VIII (pp. 168–181).DeLoach, S. A., & Garcia-Ojeda, J. C. (2010). O-mase; a customisable approach to designing and building complex, adaptive multi-agent systems. International Journal of Agent-Oriented Software Engineering, 4(3), 244–280.DeLoach, S. A., Padgham, L., Perini, A., Susi, A., & Thangarajah, J. (2009). Using three aose toolkits to develop a sample design. International Journal Agent-Oriented Software Engineering, 3, 416–476.Dignum, F., Dignum, V., Thangarajah, J., Padgham, L., & Winikoff, M. (2007). Open agent systems? Eighth international workshop on agent oriented software engineering (AOSE) in AAMAS07.Dignum, V. (2003). A model for organizational interaction:based on agents, founded in logic. PhD thesis, Utrecht University.Dignum, V., Meyer, J., Dignum, F., & Weigand, H. (2003). Formal specification of interaction in agent societies. Formal approaches to agent-based systems (Vol. 2699).Dignum, V., Vazquez-Salceda, J., & Dignum, F. (2005). Omni: Introducing social structure, norms and ontologies into agent organizations. In R. Bordini, M. Dastani, J. Dix, & A. Seghrouchni (Eds.)Programming multi-agent systems. Lecture Notes in Computer Science (Vol. 3346, pp. 181–198). Berlin: Springer.d’Inverno, M., Luck, M., Noriega, P., Rodriguez-Aguilar, J., & Sierra, C. (2012). Communicating open systems, 186, 38–94.Elsenbroich, C., & Gilbert, N. (2014). Agent-based modelling. In Modelling norms (pp. 65–84). Dordrecht: Springer.Esteva, M., Rosell, B., Rodriguez, J. A., & Arcos, J. L. (2004). AMELI: An agent-based middleware for electronic institutions. In AAMAS04 (pp. 236–243).Fenech, S., Pace, G. J., & Schneider, G. (2009). Automatic conflict detection on contracts. In Proceedings of the 6th international colloquium on theoretical aspects of computing, ICTAC ’09 (pp. 200–214).Garbay, C., Badeig, F., & Caelen, J. (2012). Normative multi-agent approach to support collaborative work in distributed tangible environments. In Proceedings of the ACM 2012 conference on computer supported cooperative work companion, CSCW ’12 (pp. 83–86). New York, NY: ACM.Garcia, E., Giret, A., & Botti, V. (2011). Regulated open multi-agent systems based on contracts. In Information Systems Development (pp. 243–255).Garcia, E., Tyson, G., Miles, S., Luck, M., Taweel, A., Staa, T. V., & Delaney, B. (2012). An analysis of agent-oriented engineering of e-health systems. In 13th international eorkshop on sgent-oriented software engineering (AOSE-AAMAS).Garcia, E., Tyson, G., Miles, S., Luck, M., Taweel, A., Staa, T. V., and Delaney, B. (2013). Analysing the Suitability of Multiagent Methodologies for e-Health Systems. In Agent-Oriented Software Engineering XIII, volume 7852, pages 134–150. Springer-Verlag.Garrido, A., Giret, A., Botti, V., & Noriega, P. (2013). mWater, a case study for modeling virtual markets. In New perspectives on agreement technologies (Vol. Law, Gover, pp. 563–579). Springer.Gteau, B., Boissier, O., & Khadraoui, D. (2006). Multi-agent-based support for electronic contracting in virtual enterprises. IFAC Symposium on Information Control Problems in Manufacturing (INCOM), 150(3), 73–91.Hollander, C. D., & Wu, A. S. (2011). The current state of normative agent-based systems. Journal of Artificial Societies and Social Simulation, 14(2), 6.Hsieh, F.-S. (2005). Automated negotiation based on contract net and petri net. In E-commerce and web technologies. Lecture Notes in Computer Science (Vol. 3590, pp. 148–157).Kollingbaum, M., Jureta, I. J., Vasconcelos, W., & Sycara, K. (2008). Automated requirements-driven definition of norms for the regulation of behavior in multi-agent systems. In Proceedings of the AISB 2008 workshop on behaviour regulation in multi-agent systems, Aberdeen, Scotland, U.K., April 2008.Li, T., Balke, T., Vos, M., Satoh, K., & Padget, J. (2013). Detecting conflicts in legal systems. In Y. Motomura, A. Butler, & D. Bekki (Eds.), New Frontiers in Artificial Intelligence (Vol. 7856, pp. 174–189)., Lecture Notes in Computer Science Berlin Heidelberg: Springer.Lomuscio, A., Qu, H., & Solanki, M. (2010) Towards verifying contract regulated service composition. Journal of Autonomous Agents and Multi-Agent Systems (pp. 1–29).Lopez, F., Luck, M., & d’Inverno, M. (2006). A normative framework for agent-based systems. Computational and Mathematical Organization Theory, 12, 227–250.Lpez, F. y, Luck, M., & dInverno, M. (2006). A normative framework for agent-based systems. Computational and Mathematical Organization Theory, 12(2–3), 227–250.Mader, P., & Egyed, A. (2012). Assessing the effect of requirements traceability for software maintenance. In 28th IEEE International Conference on Software Maintenance (ICSM) (pp. 171–180), Sept 2012.Mao, X., & Yu, E. (2005). Organizational and social concepts in agent oriented software engineering. In AOSE IV. Lecture Notes in Artificial Intelligence (Vol. 3382, pp. 184–202).Meyer, J.-J. C., & Wieringa, R. J. (Eds.). (1993). Deontic logic in computer science: Normative system specification. Chichester, UK: Wiley.Okouya, D., & Dignum, V. (2008). Operetta: A prototype tool for the design, analysis and development of multi-agent organizations (demo paper). In AAMAS (pp. 1667–1678).Malone, T. W., Smith J. B., & Olson, G. M. (2001). Coordination theory and collaboration technology. Mahwah, NJ: Lawrence Erlbaum Associates.Oren, N., Panagiotidi, S., Vázquez-Salceda, J., Modgil, S., Luck, M., & Miles, S. (2009). Towards a formalisation of electronic contracting environments. COIN (pp. 156–171).Osman, N., Robertson, D., & Walton, C. (2006). Run-time model checking of interaction and deontic models for multi-agent systems. In AAMAS ’06: Proceedings of the fifth international joint conference on Autonomous agents and multiagent systems (pp. 238–240). New York, NY: ACM.Pace, G., Prisacariu, C., & Schneider, G. (2007). Model checking contracts a case study. In Automated technology for verification and analysis. Lecture Notes in Computer Science (Vol. 4762, pp. 82–97).Rotolo, A., & van der Torre, L. (2011). Rules, agents and norms: Guidelines for rule-based normative multi-agent systems. RuleML Europe, 6826, 52–66.Saeki, M., & Kaiya, H. (2008). Supporting the elicitation of requirements compliant with regulations. In CAiSE ’08 (pp. 228–242).Siena, A., Mylopoulos, J., Perini, A., & Susi, A. (2009). Designing law-compliant software requirements. In Proceedings of the 28th international conference on conceptual modeling, ER ’09 (pp. 472–486).Singh, M. P. Commitments in multiagent systems: Some history, some confusions, some controversies, some prospects.Solaiman, E., Molina-Jimenez, C., & Shrivastav, S. (2003). Model checking correctness properties of electronic contracts. In Service-oriented computing—ICSOC 2003. Lecture Notes in Computer Science (Vol. 2910, pp. 303–318). Berlin: Springer.Telang, P. R., & Singh, M. P. (2009). Conceptual modeling: Foundations and applications. Enhancing tropos with commitments (pp. 417–435).Vázquez-Salceda, J., Confalonieri, R., Gomez, I., Storms, P., Nick Kuijpers, S. P., & Alvarez, S. (2009). Modelling contractually-bounded interactions in the car insurance domain. DIGIBIZ 2009.Viganò, F., & Colombetti, M. (2007). Symbolic model checking of institutions. In ICEC (pp. 35–44).Walton, C. D. (2007). Verifiable agent dialogues. Journal of Applied Logic, 5(2):197–213, Logic-Based Agent Verification.Winkler, S., & Pilgrim, J. (2010). A survey of traceability in requirements engineering and model-driven development. Software and Systems Modeling (SoSyM), 9(4), 529–565.Wooldridge, M., Fisher, M., Huget, M., & Parsons, S. (2002). Model checking multi-agent systems with mable. In AAMAS02 (pp. 952–959). ACM

Unexpected Diversity of Cellular Immune Responses against Nef and Vif in HIV-1-Infected Patients Who Spontaneously Control Viral Replication

Background: HIV-1-infected individuals who spontaneously control viral replication represent an example of successful containment of the AIDS virus. Understanding the anti-viral immune responses in these individuals may help in vaccine design. However, immune responses against HIV-1 are normally analyzed using HIV-1 consensus B 15-mers that overlap by 11 amino acids. Unfortunately, this method may underestimate the real breadth of the cellular immune responses against the autologous sequence of the infecting virus. Methodology and Principal Findings: Here we compared cellular immune responses against nef and vif-encoded consensus B 15-mer peptides to responses against HLA class I-predicted minimal optimal epitopes from consensus B and autologous sequences in six patients who have controlled HIV-1 replication. Interestingly, our analysis revealed that three of our patients had broader cellular immune responses against HLA class I-predicted minimal optimal epitopes from either autologous viruses or from the HIV-1 consensus B sequence, when compared to responses against the 15-mer HIV-1 type B consensus peptides. Conclusion and Significance: This suggests that the cellular immune responses against HIV-1 in controller patients may be broader than we had previously anticipated.National Institutes of Health (NIH)[R24 RR015371]Ministry of Health[914/BRA/3014-UNESCO]Sao Paulo City Health Department[2004-0.168.922-7]Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)[04/15856-9]Coordenacao de Aperfeicoamento de Pessoal de Ni-vel Superior (CAPES), Brazilian Ministry of Educatio

pH-sensitive hybrid silica with molecular recognition sites as carriers for actives compounds

Ce travail de thèse s'inscrit dans le cadre de la recherche contre le cancer, l'un des enjeux majeurs de notre société. L'objectif est d'optimiser l'action des principes actifs notamment en réduisant leurs effets secondaires chez le patient. Pour cela nous souhaitons développer des nanotransporteurs siliciques pH-sensibles capables de s'accumuler spécifiquement dans les tumeurs solides grâce à l'effet EPR.Les travaux présentés dans ce manuscrit décrivent donc la synthèse de nouveaux dérivés actifs du 5-Fluorouracile capables de former un complexe via liaisons H avec un précurseur de silice hybride possédant un motif de reconnaissance moléculaire de type triazine. Ce complexe piégé dans le solide grâce au procédé sol-gel permet alors de créer les systèmes autonomes et pH-contrôlés de délivrance de dérivé actif sans relargage prématuré. Ces systèmes, évalués in-vitro sur des cellules de cancer du sein, présentent des cytotoxicités très importantes.Les résultats encourageants obtenus laissent envisager des évaluations in-vivo de nos systèmes. Dans ce sens, nous améliorons donc actuellement nos nanomachines en introduisant un cœur d'oxyde de fer permettant le suivi par imagerie IRM et de confirmer ainsi leurs actions sur des tumeurs solides.This thesis is part of the research against cancer, one of the major challenges for our society. The objective is to optimize the action of active compounds by reducing side effects for the patient. For this we want to develop pH-sensitive silicic nanocarriers able to accumulate specifically in solid tumors through the EPR effect.The work detailed in this manuscript describes the synthesis of new 5-Fluorouracil derivatives anticancer drugs able to complex via H-bonds hybrid silica precursor with triazine molecular recognition motif. This complex trapped in the solid through sol-gel process is then used to create autonomous and pH-controlled drug delivery system with non-premature release. These systems, evaluated in-vitro on breast cancer cells, have significant cytotoxicity.The encouraging results obtained suggest in-vivo experiments for our systems. For that, we are currently improving our nanomachines by introducing a heart of iron oxide for MRI imaging and confirm their efficiency on solid tumors

Mesoporous-Silica-Functionalized Nanoparticles for Drug Delivery

International audienceThe ever-growing interest for finding efficient and reliable methods for treatment of diseases has set a precedent for the design and synthesis of new functional hybrid materials, namely porous nanoparticles, for controlled drug delivery. Mesoporous silica nanoparticles (MSNPs) represent one of the most promising nanocarriers for drug delivery as they possess interesting chemical and physical properties, thermal and mechanical stabilities, and are biocompatibile. In particular, their easily functionalizable surface allows a large number of property modifications further improving their efficiency in this field. This Concept article deals with the advances on the novel methods of functionalizing MSNPs, inside or outside the pores, as well as within the walls, to produce efficient and smart drug carriers for therap

Effect of Cannabis Smoke Condensate on C. albicans Growth and Biofilm Formation

The most common use of cannabis is smoking. The oral ecosystem, among other constituents, can be deregulated by the presence of cannabis smoke in the oral cavity. We evaluated the effect of cannabis smoke condensate (CSC) on the behavior of Candida albicans, a common yeast found in the oral cavity. The yeast was first cultured with different concentrations of CSC, and its growth was evaluated. The transition from the blastospore to the hyphal form and the hyphae size were assessed after 3 and 6 h, along with biofilm formation after 72 h of contact with CSC. The response of C. albicans to oxidative (H2O2) stress was also examined. Our results show that CSC contained high amounts of THC (about 1055 ppm), CBN (63 ppm), and CBG (about 47 ppm). The presence of various concentrations of CSC in the culture medium increased C. albicans growth. CSC also contributed to increases in both the hyphal length and biofilm mass. Following oxidative stress (H2O2 at either 100 or 500 μM), CSC prevented the damaging effect of H2O2 on both C. albicans shape and growth. These findings support clinical observations demonstrating that cannabis may promote C. albicans growth and oral candidiasis

Effect of Cannabis Smoke Condensate on <i>C. albicans</i> Growth and Biofilm Formation

The most common use of cannabis is smoking. The oral ecosystem, among other constituents, can be deregulated by the presence of cannabis smoke in the oral cavity. We evaluated the effect of cannabis smoke condensate (CSC) on the behavior of Candida albicans, a common yeast found in the oral cavity. The yeast was first cultured with different concentrations of CSC, and its growth was evaluated. The transition from the blastospore to the hyphal form and the hyphae size were assessed after 3 and 6 h, along with biofilm formation after 72 h of contact with CSC. The response of C. albicans to oxidative (H2O2) stress was also examined. Our results show that CSC contained high amounts of THC (about 1055 ppm), CBN (63 ppm), and CBG (about 47 ppm). The presence of various concentrations of CSC in the culture medium increased C. albicans growth. CSC also contributed to increases in both the hyphal length and biofilm mass. Following oxidative stress (H2O2 at either 100 or 500 μM), CSC prevented the damaging effect of H2O2 on both C. albicans shape and growth. These findings support clinical observations demonstrating that cannabis may promote C. albicans growth and oral candidiasis

Professionnalisation dans l'enseignement supérieur : quelles logiques territoriales ?

La question posée dans cette recherche est celle de l'existence d'une ou de plusieurs stratégies dans la construction de l'offre de formation professionnalisante dans l'enseignement supérieur ; la focale est placée sur l'étude des licences professionnelles, masters et doctorats. La construction de l'offre de formation y est abordée comme le résultat de coordinations complexes entre quatre catégories d'acteurs qui contribuent à cette construction : les organismes de formation, les entreprises, l'État et les collectivités territoriales.Les résultats de cette recherche reposent sur une série d'enquêtes menées dans cinq régions (Aquitaine,Bretagne, Poitou-Charentes, Provence-Alpes-Côte d'Azur et Rhône-Alpes) qui présentent des caractéristiques différentes sur plusieurs dimensions : poids des formations professionnalisantes dans l'ensemble des formations supérieures ; dynamique de professionnalisation observée au sein des universités ; structure par niveau de diplôme des formations professionnalisantes délivrées ; répartition territoriale des formations au sein de chaque région. Ils montrent que, dans leur grande majorité, les coordinations qui président à l'ouverture d'un diplôme professionnalisant dépendent d'un ensemble de variables : nature de la formation et de l'organisme qui en est porteur, comportement des demandeurs, caractéristiques des entreprises concernées par les qualifications des formés. Elles varient d'un territoire à l'autre en fonction des acteurs en présence et de la nature de leurs relations. Ainsi, l'offre de formation résulte-t-elle de constructions hybrides situées selon les territoires. On constate que les secteurs disciplinaires sont impactés différemment par la professionnalisation et que la création des licences professionnelles est particulièrement forte dans les sites universitaires secondaires. Par ailleurs, la conception de diplômes professionnalisant émane de l'initiative individuelle ou de celle d'une petite équipe en dehors d'une stratégie d'ensemble clairement affirmée. Il en découle un manque de lisibilité de l'offre de formation, que ce soit au niveau de la licence ou du master, tant pour les étudiants que pour les milieux économiques. Enfin, bien qu'ouvertes à tous les publics, les licences professionnelles tendent à professionnaliser un public qui l'est déjà. Elles permettent également d'obtenir des rémunérations plus élevées qu'avec une licence générale