Health-related quality of life in patients with Gilles de la Tourette syndrome at the transition between adolescence and adulthood

Gilles de la Tourette syndrome (GTS) is a neurodevelopmental condition characterised by tics and comorbid behavioural problems, affecting predominantly male patients. Tic severity typically fluctuates over time, with a consistent pattern showing improvement after adolescence in a considerable proportion of patients. Both tics and behavioural co-morbidities have been shown to have the potential to affect patients’ health-related quality of life (HR-QoL) in children and adults with persisting symptoms. In this study, we present the results of the first investigation of HR-QoL in patients with Gilles de la Tourette syndrome at the transition between adolescence and adulthood using a disease-specific HR-QoL measure, the Gilles de la Tourette Syndrome-Quality of Life-Children and Adolescents scale. Our results showed that patients with GTS and more severe co-morbid anxiety symptoms reported lower HR-QoL across all domains, highlighting the impact of anxiety on patient’s well-being at a critical stage of development. Routine screening for anxiety symptoms is recommended in all patients with GTS seen at transition clinics from paediatric to adult care, to implement effective behavioural and pharmacological interventions as appropriate

The birth of modern economic science Reading Gilles Campagnolo’s book

The 1870s have always held a special attraction for specialists in the history of thought. For economic theory these are the years of the Great Crossroads when economic theory was at critical breaking point, after which several powerful theoretical streams emerged that were to determine later on the overall course of the evolution of economics. The book by the French economist and philosopher Gilles Campagnolo is an attempt to find out exactly what happened in the years of the Great Crossroads. It offers not only factual and historical reading, but also theoretical interpretation to explaining the evolution, mutual influence and int ermingling of the above individual schools of thought in the economic science. The present paper is a review essay on Gilles Campagnolo’s new book.history of economic thought, Austrian analysis

Le petit livre: Gilles Clément’s paper garden

[EN] The Garden in Motion is a concept that was developed by Gilles Clément in the early 1980s as the result of the experimentation conducted in his garden-house, La Vallée. Clément’s interest in promoting this garden archetype based on managing neglected land led him to write a number of works in order to explain the conceptual underpinnings of his model, with the ultimate aim of having them published. From the writing of the first manuscripts, dating from 1984, to the first edition of “Le jardin en movement” in 1991, he produced a series of different documents that would form the basis of the text that was finally published. It was a long process in which Clément not only had to fully develop his ideas but also to overcome the difficulties involved in finding a company to publish what he called his ‘petit livre’. The aim of this article is to show the creative process behind Clément’s book and its relationship with the creative process of building his garden, while endeavouring to reply to the question of whether it is possible to establish an equivalence between both processes. This is made possible through the analysis of documents kept by Clément in his personal archive, some of which have never been published.[ES] El Jardín en Movimiento es un concepto desarrollado por Gilles Clément a principios de los años ochenta, que surge de la experimentación llevada a cabo en su casa-jardín de La Vallée. El interés por dar a conocer este arquetipo de jardín basado en la gestión del baldío, lleva a Clément a elaborar un conjunto de escritos en los que desarrolla las bases conceptuales de dicho modelo. Su objetivo final es poder llegar a publicarlos. Desde la redacción de los primeros manuscritos, que datan de 1984, hasta la primera edición de “Le jardin en mouvement” en 1991, se suceden diferentes documentos que servirán de base para el texto finalmente publicado. Un largo proceso en el que Clément no solo se enfrenta a la maduración de sus ideas, sino a las dificultades para encontrar una editorial que publique su “petit livre,” como él lo denomina. El artículo pretende mostrar la génesis de este libro y su relación con la construcción del jardín, intentado dar respuesta a la cuestión de si es posible establecer una equivalencia entre ambos procesos creativos. Todo ello a través del análisis de los documentos que Gilles Clément conserva en su archivo personal, algunos de ellos inéditos.Ávila Calzada, C. (2021). Le petit livre: el jardín de papel de Gilles Clément. VLC arquitectura. Research Journal. 8(2):1-31. https://doi.org/10.4995/vlc.2021.15357OJS13182Ávila, Carlos. "La vivencia proyectual de Gilles Clément en el Parque André-Citroën: un relato a través de sus Cuadernos de Croquis." RITA, Revista Indexada de Textos Académicos, no. 11 (2019): 56-65.Basset, Frédérique. Les quatre saisons de Gilles Clément. Paris: Rue de l'échiquier, 2014.Clément, Gilles. "Cuaderno de croquis. 1990." Unpublished manuscript. Gilles Clément personal archive, 1990.Clément, Gilles. "Cuaderno Diario. 1988-1991." Unpublished manuscript. Gilles Clément personal archive, 1991.Clément, Gilles. Eloge des vagabondes. Herbes, arbres et fleurs à la conquête du monde. Paris: Robert Laffont, 2014.Clément, Gilles. "La friche apprivoisée." Urbanisme, no. 209 (August-September 1985): 92-95.Clément, Gilles. "La friche et le jardin: le jardin en mouvement, principes d'utilisation des végétaux."Unpublished manuscript. Gilles Clément personal archive, 1984.Clément, Gilles. Le jardin en mouvement. Synopsis. Introduction et chapitre I." Unpublished manuscript. Gilles Clément personal archive. Paris, n.d.Clément, Gilles. "Jardins." Unpublished manuscript. Gilles Clément personal archive. Paris, 1984.Clément, Gilles. La sagesse du jardinier. Paris: L'oeil neuf, 2004.Clément, Gilles. Le salon des berces. Paris: NiL éditions, 2009.Clément, Gilles, Alexandre Bailhache, and Georges Lévêque. Les Libres Jardins de Gilles Clément. Paris: Éd. du Chêne, 1997.Clément, Gilles, Michael Londsdale, Jean-Marie Pelt, and Patrick Scheyder. Des jardins et des hommes. Montrouge: Bayard Éditions, 2016.Dagenais, Danielle. "The Garden of Movement: Ecological Rhetoric in Support of Gardening Practice."Studies in the History of Gardens & Designed Landscapes 24, no. 4 (2004): 313-340. https://doi.org/10.1080/14601176.2004.10435330Dagenais, Danielle, and Louisa Jones. "Gilles Clément Revisited: Biology, Art and Ecology, a Reply to Danielle Dagenais." Studies in the History of Gardens & Designed Landscapes 26, no. 3 (2006): 249-252. https://doi.org/10.1080/14601176.2006.10435469Gandy, Matthew. "Entropy by Design: Gilles Clement, Parc Henri Matisse and the Limits to AvantGarde Urbanism." International Journal of Urban and Regional Research 37, no. 1 (2013): 259-78. https://doi.org/10.1111/j.1468-2427.2012.01164.xKing, Peter, Carole Ottesen, and Graham Rose. Gardening with Style: A Private View of the World's Most Innovative Gardens. London: Bloomsbury, 1988.Paul, Anthony, and Yvonne Rees. The Garden Design Book. London: Salem House Publishers, 1988.Robinson, William. The Wild Garden, or, Our Groves and Shrubberies Made Beautiful. Cambridge: Cambridge University Press, 2011.Roger, Alain. "Dal giardino in movimento al giardino planetario." Lotus Navigator, no. 2. I Nuovi paesaggi (2001): 70-81.Skinner, Jonathan. "Gardens of Resistance: Gilles Clément, New Poetics, and Future Landscapes." Qui Parle 19, no. 2 (2011): 259-74. https://doi.org/10.5250/quiparle.19.2.0259Tortosa, Guy. "Gilles Clément-Ein Naturforscher Zu Beginn Des 21.Jahrhunderts. Gilles Clément - a Naturalist at the Dawn of the Twenty-First Century." Wachsen, no. 6 (Spring 2002): 35-47.Valéry, Marie-Françoise, and Georges Lévêque. French Garden Style. London: Frances Lincoln Ltd, 199

Experimental comparison of autodyne and heterodyne laser interferometry using a Nd:YVO4 microchip laser

Using a Nd:YVO4 microchip laser with a relaxation frequency in the megahertz range, we have experimentally compared a heterodyne interferometer based on a Michelson configuration with an autodyne interferometer based on the laser optical feedback imaging (LOFI) method regarding their signal to noise ratios. In the heterodyne configuration, the beating between the reference beam and the signal beam is realized outside the laser cavity while in the autodyne configuration, the wave beating takes place inside the laser cavity and the relaxation oscillations of the laser intensity then play an important part. For a given laser output power, object under investigation and detection noise level, we have determined the amplification gain of the LOFI interferometer compared to the heterodyne interferometer. LOFI interferometry is demonstrated to show higher performances than heterodyne interferometry for a wide range of laser power and detection level of noise. The experimental results are in good agreement with the theoretical predictions

Some aspects of electrical conduction in granular systems of various dimensions

We report on measurements of the electrical conductivity in both a 2D triangular lattice of metallic beads and in a chain of beads. The voltage/current characteristics are qualitatively similar in both experiments. At low applied current, the voltage is found to increase logarithmically in a good agreement with a model of widely distributed resistances in series. At high enough current, the voltage saturates due to the local welding of microcontacts between beads. The frequency dependence of the saturation voltage gives an estimate of the size of these welded microcontacts. The DC value of the saturation voltage (~ 0.4 V per contact) gives an indirect measure of the number of welded contact carrying the current within the 2D lattice. Also, a new measurement technique provides a map of the current paths within the 2D lattice of beads. For an isotropic compression of the 2D granular medium, the current paths are localized in few discrete linear paths. This quasi-onedimensional nature of the electrical conductivity thus explains the similarity between the characteristics in the 1D and 2D systems.Comment: To be published in The European Physical Journal

Applications of the wave packet method to resonant transmission and reflection gratings

Scattering of femtosecond laser pulses on resonant transmission and reflection gratings made of dispersive (Drude metals) and dielectric materials is studied by a time-domain numerical algorithm for Maxwell's theory of linear passive (dispersive and absorbing) media. The algorithm is based on the Hamiltonian formalism in the framework of which Maxwell's equations for passive media are shown to be equivalent to the first-order equation, $\partial \Psi/\partial t = {\cal H}\Psi$, where ${\cal H}$ is a linear differential operator (Hamiltonian) acting on a multi-dimensional vector $\Psi$ built of the electromagnetic inductions and auxiliary matter fields describing the medium response. The initial value problem is then solved by means of a modified time leapfrog method in combination with the Fourier pseudospectral method applied on a non-uniform grid that is constructed by a change of variables and designed to enhance the sampling efficiency near medium interfaces. The algorithm is shown to be highly accurate at relatively low computational costs. An excellent agreement with previous theoretical and experimental studies of the gratings is demonstrated by numerical simulations using our algorithm. In addition, our algorithm allows one to see real time dynamics of long leaving resonant excitations of electromagnetic fields in the gratings in the entire frequency range of the initial wide band wave packet as well as formation of the reflected and transmitted wave fronts.Comment: 23 pages; 8 figures in the png forma

Radial thresholding to mitigate Laser-Guide-Star aberrations on Centre-of-Gravity-based Shack-Hartmann wavefront sensors

Sodium Laser Guide Stars (LGSs) are elongated sources due to the thickness and the finite distance of the sodium layer. The fluctuations of the sodium layer altitude and atom density profile induce errors on centroid measurements of elongated spots, and generate spurious optical aberrations in closed--loop adaptive optics (AO) systems. According to an analytical model and experimental results obtained with the University of Victoria LGS bench demonstrator, one of the main origins of these aberrations, referred to as LGS aberrations, is not the Centre-of-Gravity (CoG) algorithm itself, but the thresholding applied on the pixels of the image prior to computing the spot centroids. A new thresholding method, termed ``radial thresholding'', is presented here, cancelling out most of the LGS aberrations without altering the centroid measurement accuracy.Comment: 8 pages, 9 figures, accepted for publication in MNRA

Experience of overseas-trained health professionals in rural and remote areas of destination countries: A literature review

This study aimed to review and synthesise existing literature that investigated the experience of overseastrained health professionals (OTHPs) in rural and remote areas of destination countries. A systematic literature review was conducted using electronic databases and manual search of studies published from January 2004 to February 2011. Data were analysed from the final 17 original report articles that met the inclusion criteria. The reviewed research studies were conducted in Australia, Canada, New Zealand, the UK and the USA. Overseas-trained medical practitioners were the most frequently researched (n = 14); two studies involved nurses and one study included several health professionals. Three main themes emerged from the review and these were: (i) expectations; (ii) cultural diversity; and (iii) orientation and integration to rural and remote health work environment. The OTHPs were expected to possess the appropriate professional and cultural skills while they themselves expected recognition of their previous experiences and adequate organisational orientation and support. A welcoming and accepting community coupled with a relaxed rural lifestyle and the joy of continued patient care resulted in successful integration and contributed to increased staff retention rates. Recognition of expectations and cultural diversity by all parties and comprehensive orientation with sufficient organisational support are important elements in the integration of OTHPs and subsequent delivery of quality health care to people living in rural and remote areas

Securing By Design

This article investigates how modern neo-liberal states are 'securing by design' harnessing design to new technologies in order to produce security, safety, and protection. We take a critical view toward 'securing by design' and the policy agendas it produces of 'designing out insecurity' and 'designing in protection' because securing by design strategies rely upon inadequate conceptualisations of security, technology, and design and inadequate understandings of their relationships to produce inadequate 'security solutions' to readymade 'security problems'. This critique leads us to propose a new research agenda we call Redesigning Security. A Redesigning Security Approach begins from a recognition that the achievement of security is more often than not illusive, which means that the desire for security is itself problematic. Rather than encouraging the design of 'security solutions' a securing by design a Redesigning Security Approach explores how we might insecure securing by design. By acknowledging and then moving beyond the new security studies insight that security often produces insecurity, our approach uses design as a vehicle through which to raise questions about security problems and security solutions by collaborating with political and critical design practitioners to design concrete material objects that themselves embody questions about traditional security and about traditional design practices that use technology to depoliticise how technology is deployed by states and corporations to make us 'safe'