Proctology in the COVID-19 era: handle with care

The Italian outbreak of COVID-19 was confirmed on 31 January 2020 when two COVID-19-positive cases were reported in Chinese tourists. At the beginning, the vast majority of cases were reported in the northern regions of Italy with establishment of the so-called ‘red zone’. On 9March 2020, the Italian prime minister declared a nationwide lockdown to strengthen the national health system (Sistema Sanitario Nazionale). Italy has one of the highest rates of infection and mortality in the worl

Nuclear and Non-Ionizing Energy-Loss for Coulomb Scattered Particles from Low Energy up to Relativistic Regime in Space Radiation Environment

In the space environment, instruments onboard of spacecrafts can be affected by displacement damage due to radiation. The differential scattering cross section for screened nucleus--nucleus interactions - i.e., including the effects due to screened Coulomb nuclear fields -, nuclear stopping powers and non-ionization energy losses are treated from about 50 keV/nucleon up to relativistic energies.Comment: Accepted for publication in the Proceedings of the ICATPP Conference on Cosmic Rays for Particle and Astroparticle Physics, Villa Olmo (Como, Italy), 7--8 October, 2010, to be published by World Scientifi

The source and the age of the soil organic matter of Anthrosols in SW Norway

Recent investigations showed that humus‑rich topsoil’s around the Baltic Sea have been formed by the application of pyrogenic organic matter (Acksel et al., 2016, Geoderma Reg. 7, 187–200) and organic materials (e.g. animal manure, organic waste) linked with human activity and, consequently, these soils were classified as Anthrosols (Acksel et al., 2017 (submitted)). Such humus‑rich topsoil’s, which were strongly influenced by anthropogenic activities and classified as plaggic Anthrosols, were described in SW Norway (Schnepel et al., 2014, J. Plant Nutr. Soil Sci., 177 (4), 638–645.). However, the source and the formation time of the Anthrosols in Norway have not been investigated in detail. Therefore, we characterized the soil organic matter composition by pyrolysis-field ionisation-mass spectrometry (Py-FIMS), benzene polycarboxylic acids (BPCA) determination, examined the source of the SOM by isotopic signatures (d34S) and estimated the age of the SOM by 14C AMS dating in order to find out the beginning of Anthrosol formation. Py-FIMS revealed high portions of sterols and fatty acids, indicating inputs of manure, similar to plaggic Anthrosols in NW Germany. The BC portions (≈ 19 % BC of Corg) were similar to various Anthrosols (≈ 25 % BC of Corg) and Chernozems (≈ 13 % BC of Corg) worldwide and indicated an input of combustion residues to soils by early fire events. The d34S isotope signature of the SOM ranged from 10 to 13.4 ‰ at the islands and 10.6 to 15.2 in the Jaeren region of SW Norway, corresponded to the Anthrosols in the Baltic Sea region (Median: d34S = 11.5 ‰) and indicated an input of marine biomass (d34S of seaweed = 20 ‰). All these results complemented the study of Schnepel et al. (2014) and provided strong evidence that these soils were formed by human activities. Ongoing analyses of 14C ages from these soils enable to estimate the timing of the soil formation and link it to settlement history

UM ROLE PLAYING GAME PARA O ENSINO DE ELICITAÇÃO E ANÁLISE DE REQUISITOS

A engenharia de requisitos objetiva estabelecer o entendimento do problema e as necessidades do cliente. No entanto, o processo de ensino desta competência nem sempre é satisfatório, por ser um conteúdo teórico, muitos professores utilizam somente aulas expositivas, onde acaba limitando o aprendizado dos alunos. Assim, surge a necessidade de explorar novos métodos de ensino, como os jogos educacionais, de modo a criar um ambiente que desperte o interesse dos alunos. O objetivo deste trabalho é desenvolver e avaliar um jogo educacional do tipo RPG no qual o jogador atuará como um engenheiro de requisitos coletando e priorizando os requisitos em um cenário simulado. Uma avaliação sistemática realizada aponta resultados satisfatórios quanto a motivação, experiência do usuário e aprendizagem dos alunos

Lumbar epidural fentanyl: segmental spread and effect on temporal summation and muscle pain

Background. Despite extensive use, different aspects of the pharmacological action of epidural fentanyl have not been clarified. We applied a multi‐modal sensory test procedure to investigate the effect of epidural fentanyl on segmental spread, temporal summation (as a measure for short‐lasting central hyperexcitability) and muscle pain. Methods. Thirty patients received either placebo, 50 or 100 µg single dose of fentanyl epidurally (L2-3), in a randomized, double‐blind fashion. Heat pain tolerance thresholds at eight dermatomes from S1 to fifth cranial nerve (assessment of segmental spread), pain threshold to transcutaneous repeated electrical stimulation of the sural nerve (assessment of temporal summation) and pain intensity after injection of hypertonic saline into the tibialis anterior muscle (assessment of muscle pain) were recorded. Results. Fentanyl 100 µg, but not 50 µg, produced analgesia to heat stimulation only at L2. Surprisingly, no effect at S1 was detected. Both fentanyl doses significantly increased temporal summation threshold and decreased muscle pain intensity. Conclusions. The findings suggest that a single lumbar epidural dose of fentanyl should be injected at the spinal interspace corresponding to the dermatomal site of pain. Increased effect on L2 compared with S1 suggests that drug effect on spinal nerve roots and binding to opioid receptors on the dorsal root ganglia may be more important than traditionally believed for the segmental effect of epidurally injected fentanyl. Epidural fentanyl increases temporal summation threshold and could therefore contribute to prevention and treatment of central hypersensitivity states. I.M. injection of hypertonic saline is a sensitive technique for detecting the analgesic action of epidural opioids. Br J Anaesth 2003; 90: 467-7

Guidelines for the study of subsidence triggered by hydrocarbon production

This study was carried out by the SEADOG Research Center at Politecnico di Torino (Italy). The purpose of this work was to evaluate which complexity degree would be required to reliably approach a subsidence study for different scenarios. The study was based on sensitivity analyses which were performed using a series of 3D synthetic numerical models of which the structural characteristics and geological and mechanical properties were based on available public data of onshore and offshore hydrocarbon fields in Italy. An array of simulations, both one-way and two-way coupled, were carried out to assess the magnitude and extension of subsidence potentially induced by hydrocarbon production. The results allowed the calculation of subsidence indices defined as the rate of compaction propagation (i.e., the ratio between the maximum surface displacement and the maximum reservoir compaction) and as the rate of volume loss (i.e. the ratio between the volume of the subsidence bowl or cone and the volume variation of the reservoir). These indices together with the degree of the underground systems’ heterogeneity led to the definition of the Intact Rock Qualitative Subsidence Index (IRQSI), upon which the needed complexity degree of a subsidence study can be discerned

GIANO-TNG spectroscopy of red supergiants in the young star cluster RSGC3

The Scutum complex in the inner disk of the Galaxy has a number of young star clusters dominated by red supergiants that are heavily obscured by dust extinction and observable only at infrared wavelengths. These clusters are important tracers of the recent star formation and chemical enrichment history in the inner Galaxy. During the technical commissioning and as a first science verification of the GIANO spectrograph at the Telescopio Nazionale Galileo, we secured high-resolution (R=50,000) near-infrared spectra of five red supergiants in the young Scutum cluster RSGC3. Taking advantage of the full YJHK spectral coverage of GIANO in a single exposure, we were able to measure several tens of atomic and molecular lines that were suitable for determining chemical abundances. By means of spectral synthesis and line equivalent width measurements, we obtained abundances of Fe and iron-peak elements such as Ni, Cr, and Cu, alpha (O, Mg, Si, Ca, Ti), other light elements (C, N, F, Na, Al, and Sc), and some s-process elements (Y, Sr). We found average half-solar iron abundances and solar-scaled [X/Fe] abundance patterns for most of the elements, consistent with a thin-disk chemistry. We found depletion of [C/Fe] and enhancement of [N/Fe], consistent with standard CN burning, and low 12C/13C abundance ratios (between 9 and 11), which require extra-mixing processes in the stellar interiors during the post-main sequence evolution. We also found local standard of rest V(LSR)=106 km/s and heliocentric V(HEL)=90 km/s radial velocities with a dispersion of 2.3 km/s. The inferred radial velocities, abundances, and abundance patterns of RSGC3 are very similar to those previously measured in the other two young clusters of the Scutum complex, RSGC1 and RSGC2, suggesting a common kinematics and chemistry within the Scutum complex

Rapid detection of intestinal carriage of Klebsiella pneumoniae producing KPC carbapenemase during an outbreak

n/