875 research outputs found
TCT-255 Effectiveness Of Preprocedural Statin Administration In Reducing ContrastâInduced Acute Kidney Injury: A MetaâAnalysis Of Randomized Controlled Trials
Muons tomography applied to geosciences and volcanology
Imaging the inner part of large geological targets is an important issue in
geosciences with various applications. Dif- ferent approaches already exist
(e.g. gravimetry, electrical tomography) that give access to a wide range of
informations but with identified limitations or drawbacks (e.g. intrinsic
ambiguity of the inverse problem, time consuming deployment of sensors over
large distances). Here we present an alternative and complementary tomography
method based on the measurement of the cosmic muons flux attenuation through
the geological structures. We detail the basics of this muon tomography with a
special emphasis on the photo-active detectors.Comment: Invited talk at the 6th conference on New Developments In
Photodetection (NDIP'11), Lyon-France, July 4-8, 2011; Nuclear Instruments
and Methods in Physics Research Section A, 201
Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids
Traumatic spinal cord injury (SCI) represents one of the most disabling injuries of the human body causing temporary or permanent sensory and/or motor system deficit, particularly hind limb locomotor function impairment. At present, steroidal inflammatory drugs, in particular methylprednisolone sodium succinate (MPSS) are the first line choice treatment of acute SCI. Despite progress in pharmacological, surgical and rehabilitative treatment approaches, SCI still remains a very complex medical and psychological challenge, with no curative therapy available. The aim of the present study was to compare the efficacy of MPSS in respect to other GCs such as dexamethasone (Dex) and mometasone furoate (MF) in an in vitro suitable model of LPS-induced inflammation in J774 cells as well as in an in vivo experimental mouse SCI (compression model). In both the in vitro and in vivo experiments, MF resulted surprisingly more potent than Dex and MPSS. In detail, mice sacrificed seven days after induction of SCI trauma resulted not only in tissue damage, cellular infiltration, fibrosis, astrocyte activation, iNOS expression, extracellular signal regulated kinase 1/2 phosphorylation in injured tissue, poly (ADP-ribose) polymerase 1 (PARP-1) activation but also apoptosis (Bax and Bcl-2 expression). All three GCs demonstrated the ability to modulate inflammatory, oxidative as well as apoptotic pathways, but MF demonstrated the best efficacy, while Dex and MPSS showed alternative potency with a different degree of protection. Therefore, we can conclude that MF is the best candidate for post-traumatic chronic treatment, since it ameliorates different molecular pathways involved in the damage's propagation to the surrounding areas of the injured spinal cord
Neutron-skin thickness of Pb, and symmetry-energy constraints from the study of the anti-analog giant dipole resonance
The Pb(,) Pb reaction at a beam energy of
30 MeV has been used to excite the anti-analog of the giant dipole resonance
(AGDR) and to measure its -decay to the isobaric analog state in
coincidence with proton decay of IAS. The energy of the transition has also
been calculated with the self-consistent relativistic random-phase
approximation (RRPA), and found to be linearly correlated to the predicted
value of the neutron-skin thickness (). By comparing the
theoretical results with the measured transition energy, the value of 0.190
0.028 fm has been determined for of Pb, in
agreement with previous experimental results. The AGDR excitation energy has
also been used to calculate the symmetry energy at saturation (
MeV) and the slope of the symmetry energy ( MeV), resulting in
more stringent constraints than most of the previous studies.Comment: 6 pages, 5 figures. arXiv admin note: text overlap with
arXiv:1205.232
Past, present and future of radioactive ion beams produced In-Flight at LNS
The FRIBs@LNS facility produces Radioactive Ion Beams (RIBs)
at intermediate energies, by projectile fragmentation. The possibility of using the produced RIBs as secondary beams in nuclear physics experiments by applying the tagging technique, i.e. the identification, event-by-event, in charge, mass and energy of each ion of the RIBs cocktail selected by the fragment separator, before it interacts with the secondary target, has been demonstrated. In 2010 an upgrade of the facility has been performed. Status and perspectives of the FRIBs@LNS facility are discussed
Scissors resonance in the quasi-continuum of Th, Pa and U isotopes
The gamma-ray strength function in the quasi-continuum has been measured for
231-233Th, 232,233Pa and 237-239U using the Oslo method. All eight nuclei show
a pronounced increase in gamma strength at omega_SR approx 2.4 MeV, which is
interpreted as the low-energy M1 scissors resonance (SR). The total strength is
found to be B_SR = 9-11 mu_N^2 when integrated over the 1 - 4 MeV gamma-energy
region. The SR displays a double-hump structure that is theoretically not
understood. Our results are compared with data from (gamma, gamma') experiments
and theoretical sum-rule estimates for a nuclear rigid-body moment of inertia.Comment: 11 pages, 9 figure
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