Reducing the number of miscreant tasks executions in a multi-use cluster.

Exploiting computational resources within an organisation for more than their primary task offers great benefits – making better use of capital expenditure and provides a pool of computational power. This can be achieved through the deployment of a cycle stealing distributed system, where tasks execute during the idle time on computers. However, if a task has not completed when a computer returns to its primary function the task will be preempted, wasting time (and energy), and is often reallocated to a new resource in an attempt to complete. This becomes exacerbated when tasks are incapable of completing due to excessive execution time or faulty hardware / software, leading to a situation where tasks are perpetually reallocated between computers – wasting time and energy. In this work we investigate techniques to increase the chance of ‘good’ tasks completing whilst curtailing the execution of ‘bad’ tasks. We demonstrate, through simulation, that we could have reduce the energy consumption of our cycle stealing system by approximately 50%

Two complete syntheses of (S)-aspartate semi-aldehyde and demonstration that Delta(2)-tetrahydroisophthalic acid is a non-competitive inhibitor of dihydrodipicolinate synthase

The document attached has been archived with permission from the publisher.We report, in full, two 3-step syntheses of (S)-aspartate semi-aldehyde, an important synthetic and biosynthetic precursor, from diprotected aspartic acid. The first synthesis proceeds via a thioester, the second via a Weinreb amide. Each route yields pure (S)-aspartate semi-aldehyde in excellent yield. The utility of (S)-aspartate semi-aldehyde prepared in this manner was demonstrated with an inhibition study of dihydrodipicolinate synthase, wherein Δ2- tetrahydroisophthalic acid is shown to be a non-competitive inhibitor with respect to both substrates.Sarah J. Roberts, Jonathan C. Morris, Renwick C.J. Dobson, Chris L. Baxter, and Juliet A. Gerrar

Styrene degradation in perlite biofilter: the overall performance characteristics and dynamic response

[Abstract] Styrene’s degradation in a perlite biofilter including the long-term operation, dynamic response to step-changes in inlet concentration and non-use periods were tested. The study was performed in a bench-scale biofilter with ID 100 mm and a bed height of 1 m. Perlite with a particle size of 2 – 4 mm was used as a packing material. An enrichment mixed culture was immobilized on the packing. The inoculum was obtained from a styrene biofilter. Two different loading conditions were tested: (1) Loading with a high inlet concentration and a high residence time. (2) Loading with a low inlet concentration and the low residence time. Both conditions are common in industrial practice. The dynamic response to a repeated step-change in the inlet concentration (from 50 to 200 mg.m-3) was tested. The dynamic behaviour of the restarting period after varying periods of non-use was also investigated. The results demonstrate a high biofilter stability under extreme loading conditions and also during the step-changes of the inlet concentration. The non-use periods tested had almost no effect on the biofilter performance. The maximum outlet concentration after the restarting of the load was 4 mg.m-3, when a 95 hours idle period was used. After shorter idle periods, the outlet styrene concentrations did not exceed 0.6 mg.m-3

Mimicking the impact of infant tongue peristalsis on behaviour of solid oral dosage forms administered during breastfeeding

An in vitro simulation system was developed to study the effect of an infant’s peristaltic tongue motion during breastfeeding on oral rapidly disintegrating tablets in the mouth, for use in rapid product candidate screening. These tablets are being designed for use inside a modified nipple shield worn by a mother during breastfeeding, a proposed novel platform technology to administer drugs and nutrients to breastfeeding infants. In this study, the release of a model compound, sulforhodamine B, from tablet formulations was studied under physiologically relevant forces induced by compression and rotation of a tongue mimic. The release profiles of the sulforhodamine B in flowing deionised water were found to be statistically different using 2-way ANOVA with matching, when tongue mimic rotation was introduced for two compression levels representing two tongue strengths (P=0.0013 and P<0.0001 for the lower and higher compression settings, respectively). Compression level was found to be a significant factor for increasing model compound release at rotational rates representing non-nutritive breastfeeding (P=0.0162). This novel apparatus is the first to simulate the motion and pressures applied by the tongue, and could be used in future infant oral product development

The triggering of MHD instabilities through photospheric footpoint motions

The results of 3D numerical simulations modelling the twisting of a coronal loop due to photospheric vortex motions are presented. The simulations are carried out using an initial purely axial field and an initial equilibrium configuration with twist, . The non-linear and resistive evolutions of the instability are followed. The magnetic field is twisted by the boundary motions into a loop which initially has boundary layers near the photospheric boundaries as has been suggested by previous work. The boundary motions increase the twist in the loop until it becomes unstable. For both cases the boundary twisting triggers the kink instability. In both cases a helical current structure wraps itself around the kinked central current. This current scales linearly with grid resolution indicating current sheet formation. For the cases studied 35-40% of the free magnetic energy is released. This is sufficient to explain the energy released in a compact loop flare

Transverse Shifts in Paraxial Spinoptics

The paraxial approximation of a classical spinning photon is shown to yield an "exotic particle" in the plane transverse to the propagation. The previously proposed and observed position shift between media with different refractive indices is modified when the interface is curved, and there also appears a novel, momentum [direction] shift. The laws of thin lenses are modified accordingly.Comment: 3 pages, no figures. One detail clarified, some misprints corrected and references adde

Simulations of a lattice model of two-headed linear amphiphiles: influence of amphiphile asymmetry

Using a 2D lattice model, we conduct Monte Carlo simulations of micellar aggregation of linear-chain amphiphiles having two solvophilic head groups. In the context of this simple model, we quantify how the amphiphile architecture influences the critical micelle concentration (CMC), with a particular focus on the role of the asymmetry of the amphiphile structure. Accordingly, we study all possible arrangements of the head groups along amphiphile chains of fixed length $N=12$ and 16 molecular units. This set of idealized amphiphile architectures approximates many cases of symmetric and asymmetric gemini surfactants, double-headed surfactants and boloform surfactants. Consistent with earlier results, we find that the number of spacer units $s$ separating the heads has a significant influence on the CMC, with the CMC increasing with $s$ for $s<N/2$. In comparison, the influence of the asymmetry of the chain architecture on the CMC is much weaker, as is also found experimentally.Comment: 30 pages, 17 fgure

Numerical simulations of kink instability in line-tied coronal loops

The results from numerical simulations carried out using a new shock-capturing, Lagrangian-remap, 3D MHD code, Lare3d are presented. We study the evolution of the m=1 kink mode instability in a photospherically line-tied coronal loop that has no net axial current. During the non-linear evolution of the kink instability, large current concentrations develop in the neighbourhood of the infinite length mode rational surface. We investigate whether this strong current saturates at a finite value or whether scaling indicates current sheet formation. In particular, we consider the effect of the shear, defined by where is the fieldline twist of the loop, on the current concentration. We also include a non-uniform resistivity in the simulations and observe the amount of free magnetic energy released by magnetic reconnection

Development of low-cost multi-wavelength imager system for studies of aurora and airglow

This paper introduces a new system that can monitor aurora and atmospheric airglow using a low-cost Watec monochromatic imager (WMI) equipped with a sensitive camera, a filter with high transmittance, and the non-telecentric optics. The WMI system with 486-nm, 558-nm, and 630-nm band-pass filters has observable luminosity of about ~200–4000 Rayleigh for 1.07-sec exposure time and about ~40–1200 Rayleigh for 4.27-sec exposure time, for example. It is demonstrated that the WMI system is capable of detecting 428-nm auroral intensities properly, through comparison with those measured with a collocated electron-multiplying charge-coupled device (EMCCD) imager system with narrower band-pass filter. The WMI system has two distinct advantages over the existing system: One makes it possible to reduce overall costs, and the other is that it enables the continuous observation even under twilight and moonlight conditions. Since 2013 a set of multi-wavelength WMIs has been operating in northern Scandinavia, Svalbard, and Antarctica to study meso- and large-scale aurora and airglow phenomena. Future development of the low-cost WMI system is expected to provide a great opportunity for constructing a global network for multi-wavelength aurora and airglow monitoring

Nitrogen recycling from the xylem in rice leaves: dependence upon metabolism and associated changes in xylem hydraulics

Measurements of amino acids in the guttation fluid and in the xylem exudates of cut leaves from intact plants provide evidence of the remarkable efficiency with which these nitrogenous compounds are reabsorbed from the xylem sap. This could be achieved by mechanisms involving intercellular transport and/or metabolism. Developmental changes in transcripts and protein showed that transcripts for phosphoenolpyruvate carboxykinase (PEPCK) increased from the base to the leaf tip, and were markedly increased by supplying asparagine. Supplying amino acids also increased the amounts of protein of PEPCK and, to a lesser extent, of pyruvate, Pi dikinase. PEPCK is present in the hydathodes, stomata and vascular parenchyma of rice leaves. Evidence for the role of PEPCK was obtained by using 3-mercaptopicolinic acid (MPA), a specific inhibitor of PEPCK, and by using an activation-tagged rice line that had an increase in PEPCK activity, to show that activation of PEPCK resulted in a decrease in N in the guttation fluid and that treatment by MPA resulted in an increase in amino acids in the guttation fluid and xylem sap towards the leaf tip. Furthermore, increasing PEPCK activity decreased the amount of guttation fluid, whereas decreasing PEPCK activity increased the amount of xylem sap or guttation fluid towards the leaf tip. The findings suggest the following hypotheses: (i) both metabolism and transport are involved in xylem recycling and (ii) excess N is the signal involved in modulating xylem hydraulics, perhaps via nutrient regulation of water-transporting aquaporins. Water relations and vascular metabolism and transport are thus intimately linked