26 research outputs found
Acute increase of alpha-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation
- Author
- Abeliovich A
- Andersson F
- Bendor JT
- Boassa D
- Bolte S
- Brodin L
- Brodin L
- Buchanan JT
- Buckley K
- Burre J
- Burre J
- Busch DJ
- Bussell R
- Chandra S
- Chandra S
- Chiba-Falek O
- Clayton EL
- Clayton EL
- Cousin MA
- David J. Busch
- Davidson WS
- Dawson TM
- Di Paolo G
- Di Prisco GV
- Dubuc R
- Dumitriu A
- Dunn KW
- Eliezer D
- Fiala JC
- Ford MG
- Fortin DL
- Gaugler MN
- George JM
- Granseth B
- Greten-Harrison B
- Heerssen H
- Heuser JE
- Jennifer R. Morgan
- Julia M. George
- Kramer ML
- Kruger R
- Larsen KE
- Lau BY
- Lee VM
- Lundblad M
- Maroteaux L
- Morgan JR
- Morgan JR
- Morgan JR
- Morgan JR
- Murphy DD
- Nakamura K
- Nemani VM
- Oliphint PA
- Paul A. Oliphint
- Perrin RJ
- Pieribone VA
- Polymeropoulos MH
- Ringstad N
- Rovainen CM
- Rylie B. Walsh
- Saheki Y
- Sandra Lemmon
- Schweizer FE
- Scott D
- Scott DA
- Senior SL
- Shupliakov O
- Singleton AB
- Slepnev VI
- Spillantini MG
- Spinelli KJ
- Sun Z
- Surguchov A
- Susan M. L. Banks
- Ulmer TS
- Ulmer TS
- Vargas KJ
- Volpicelli-Daley LA
- von Kleist L
- Wendy S. Woods
- Wenzel EM
- Westphal CH
- Wickelgren WO
- Zarranz JJ
- Publication venue
- 'American Society for Cell Biology (ASCB)'
- Publication date
- 01/10/2014
- Field of study
This work was supported by grants from the NIH/National Institute
of Neurological Disorder and Stroke RO1 NS078165 (to J.R.M.),
the Morton Cure Paralysis Fund (to J.R.M.), and the Branfman Family
Foundation (to J.M.G.) and by a Dorothea Bennett graduate
fellowship (to D.J.B.)
Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study
- Author
- Aba M
- Abdellatif M
- Abdelmahmoud S
- Abu Hassan F
- Acil C
- Adarkwah P
- Adarraga J
- Adderley O
- Adefolaju A
- Afzal A
- Afzal Z
- Agarwal H
- Agnes A
- Agostinelli L
- Ahari D
- Ahmad H
- Ahmad R
- Ahmad S
- Ahmed N
- Ahmed N
- Ahmed WUR
- Ahmed WUR
- Akhbari M
- Akintunde A
- Akkaya YM
- Akram J
- Aktas MK
- Aktas MK
- Aktas MK
- Aktaş A
- Akula Y
- Al Nassrallah M
- Al-Habsi R
- Alam F
- Albino V
- Alfadhel S
- Ali T
- Alicata F
- Aljić A
- Allison W
- Almeida T
- Alonso Batanero E
- Alonso Batanero E
- Alsaif A
- Alsusa H
- Altaf R
- Altay L
- Altinel Y
- Altiner S
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- Altomare DF
- Altunsu S
- Alvarez-Gallego M
- Amendola A
- Amjad T
- Amjad T
- Anabitarte Bautista O
- Anastasi A
- Anderson K
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- Atzeni J
- Augestad KM
- Aulicino M
- Aung MT
- Auterson L
- Aversano A
- Axmarker T
- Aydin R
- Azizan N
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- Özbalcı GS
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- Öztürk OU
- Čustović S
- Štefanová H
- Ευσταθίου Η
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- Chandrakumar C
- Chang K
- Chang Ky
- Chapman A
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- Charles A
- Cheah Aez
- Chen Cy
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- Chong Cl
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- De Franciscis S
- De Freitas AVC
- De La Medina AR
- de Leó
- De Leon MZP
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- de Lima CVB
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- Debrah S
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- Deichsel F
- Del Basso C
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- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
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- Despotidis V
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- Deutschmann P
- Devadasar Gh
- Dharamshi Ha
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- Di Martino N
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- Diab A
- Diaconescu B
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- Dias S
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- Din F
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- Dissanayake T
- Djivoh F
- Domini E
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- Donoghue D
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- Drungilas M
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- El Hamid NA
- El Jamassi A
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- El Mesery S
- El Salam YA
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- El Sayed IM
- El Shoura Y
- El Slam MA
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- El-Din Ra
- El-Din Sa
- El-Gizawy E
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- El-Kashef H
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- El-Sagheer N
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- Elashmawy M
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- Elbatahgy A
- Elbe P
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- Eldafrawy M
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- Eldeeb Az
- Eldeen Ea
- Eldin Mab
- Elebute O
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- Elena G
- Elfarargy A
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- Elgendy Fi
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- Elkelany A
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- Elkholy A
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- Elkorashy Am
- Ellison Q
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- Elnajjar Ma
- Elnemr Ae
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- Elsabbagh N
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- Elsherif Fa
- Elshobary M
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- Elzayat I
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- Elzowawi F
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- Eng C
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- Escobar Eg.
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- Espinoza F
- Espinoza Kt
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- Estupinian S
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- Etienne S
- Etman M
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- Evans D
- Evans E
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- Ezzat T
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- Farhangmehr N
- Farinella E
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- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
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- Fermani C
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- Fitzgerald Je
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- Fourcade L
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- Frade F
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- Fujii F
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- Gala T
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- Gudal A
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- Guevara R
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- Gulielmi A
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- Ibrahem Aa
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- Ibrahim A
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- Lim Pj
- Lim Sj
- Lim Sj
- Lim Sy
- Limache S
- Limaye N
- Limoges B
- Lintin L
- Lipnickas V
- Litvin A
- Liu Q
- Liu Q
- Livesey A
- Livingston M
- Ljuhar D
- Lo Conte A
- Loaloa Mr
- Lockey J
- Lohse Has
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- Loizides S
- Lokman Maa
- Longstaff L
- Lopez Ce
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- Lopez M
- Lopez M
- Lopez-Arevalo C
- Lorenzon L
- Lossius Wj
- Loughran D
- Low X
- Luc Ar
- Luck J
- Luck J
- Luck J
- Luglio G
- Lund J
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- Lundgren Po
- Luque Gb
- Luque L
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- Lytras D
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- Má
- Mé
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- Mañ
- Ma J
- Mabitsela Me
- Mabrouk M
- Macchiavello R
- Macchitella Y
- Macchitella Y
- Macdermid E
- Macdonald A
- Macdonald E
- Macdonald L
- Maceviciute K
- Macfarlane A
- Machaca M
- Maciejec L
- Madiba T
- Madkor Mh
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
- Magdy E
- Magdy H
- Magdy M
- Magdy S
- Magee C
- Maghrabi A
- Maghrabi Aa
- Magri D
- Mahamood Ab
- Mahanty S
- Maharaj G
- Mahdi A
- Mahdi S
- Mahdi S
- Maher Me
- Mahmoud B
- Mahmoud H
- Mahmoud M
- Mahmoud Ma
- Mahmoud Mi
- Mahmoud S
- Mahmoud Sme
- Mahmud K
- Maillot B
- Maimbo M
- Maimbo M
- Mairs Ng
- Maison K
- Maistry N
- Majauskyté
- Majbar A
- Majid Ahha
- Majid K
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- Major P
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- Mak T
- Makama J
- Makinde M
- Makupe A
- Malavenda M
- Malik K
- Malik P
- Malik Ta
- Mamdouh E
- Mamdouh R
- Manatakis Dk
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal Ce
- Maniscalco A
- Mann T
- Mannu Gs
- Manriquez-Reyes M
- Mansor Ey
- Mansour B
- Mansour S
- Mansuri A
- Mao P
- Mapasse D
- Maple N
- Maraie N
- Marey A
- Marey As
- Margaritis M
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
- Mas R
- Mason C
- Mata Lps
- Matheu A
- Mathew Sw
- Matos-Puig R
- Matta Jjh
- Mattar O
- Matter Sm
- Mauro L
- Mayasari M
- Mazelyte R
- Mazrimas P
- Mazzella A
- Mcaleer E
- Mcaleer S
- Mccarthy K
- Mccarthy M
- Mccarthy M
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- Mcdonald R
- McGarvie S
- Mcguigan A
- McIntosh K
- Mcintosh R
- Mcintyre Cj
- Mcintyre N
- Mcintyre R
- Mckechnie D
- Mclachlan G
- Mclean Al
- Mclean K
- McMorran D
- Mcnish D
- Mcphee A
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- Mehdi A
- Mehrez S
- Mejia Agv
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- Melo R
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- Mendizabal Caa
- Mendoza I
- Menegussi J
- Mensah E
- Menshawy A
- Mentula P
- Meqbil J
- Mericliler M
- Merlini D
- Merlini D
- Merlo Ms
- Mesbah N
- Meshref A
- Metwally Mm
- Migliore M
- Miguel Gps
- Mihaljevic Al
- Mihanovic J
- Mihanovic J
- Mijuskovic B
- Mikalauskas S
- Mikalauskas S
- Mikuckyte D
- Mikwar Z
- Milligan W
- Milligan W
- Mingrone P
- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu As
- Mironescu As
- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
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- Mittal A
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- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo Mm
- Modolo Mm
- Modolo Mm
- Moe Tt
- Mogan Yp
- Moghazy Me
- Mohamed A
- Mohamed A
- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed Ae
- Mohammed Ar
- Mohammed H
- Mohammed Mm
- Mohammed Mmh
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok Yt
- Mokhtar A
- Molina G
- Mollo Mc
- Monaghan E
- Monaghan E
- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora Jjv
- Morais Pab
- Morales C
- Moran Aer
- Morandi E
- Moreira G
- Moreno Sc
- Morgan C
- Morgan C
- Morshedy Em
- Morsi A
- Morsi M
- Morton D
- Morton D
- Morton R
- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
- Msosa V
- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
- Muller C
- Munera A
- Munhoz Mm
- Munipalle Pc
- Muntean L
- Muntean Li
- Muralha N
- Murphy J
- Murray A
- Murutoglu B
- Musa Aek
- Musleh A
- Musowoya J
- Mussad A
- Mustafa M
- Mustafa M
- Mustafa Ma
- Musyoka Ck
- Mutabazi Az
- Mutabazi Az
- Mutlu D
- Mutlu V
- Muzio E
- Myers J
- Mykoniatis I
- Næ
- Nabawi A
- Nada F
- Nadeem N
- Nadkarni S
- Nagy Gs
- Nahar Sn
- Nair H
- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
- Naqvi T
- Naranjo Aristizã
- Narayanan R
- Narayanan R
- Narvestad Jk
- Nashaat A
- Nashat M
- Nasher O
- Nashidengo P
- Nasir A
- Nasir Aa
- Nasr A
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- Nasr M
- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
- Nawawi A
- Nawawi A
- Nayel Ar
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu Sr
- Ndwambi P
- Ne&apos
- Negida A
- Negoi I
- Nel D
- Nemeth K
- Neo Yn
- Neo Yt
- Neophytou C
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nepogodiev D
- Nesaratnam A
- Nessa A
- Nestorovic M
- Nevieraite V
- Newton T
- Ng S
- Ng Yk
- Ng Zh
- Ngayu N
- Ngwa Te
- Niazi Ak
- Nicholson L
- Nighat B
- Nigo S
- Nikberg M
- Nikoloudis N
- Nikoloudis N
- Niragire A
- Niranjan N
- Nirumal Mk
- Niska K
- Nita Ge
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- Niyirera E
- Njokanma I
- Nnajiuba H
- Nocito A
- Nocito A
- Nofal E
- Noor F
- Normile C
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- North As
- Notarnicola M
- Notarnicola M
- Nouh T
- Nouh T
- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
- Nsengiyumva C
- Ntirenganya F
- Nur&apos
- Nurqistan Hd
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
- Nymo L
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- O&apos
- Obute Rd
- Occhionorelli S
- Odeyemi B
- Odeyemi B
- Odutola O
- Ogunsua O
- Ogunyemi A
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- Oh J
- Ohene-Yeboah M
- Ojeda Rrb
- Okenabirhie O
- Olajide To
- Olaolorun A
- Olivier J
- Olori S
- Olori S
- Oludara M
- Oludara M
- Olugbemi M
- Omar Aa
- Omar Me
- Omar Mfw
- Omara S
- Omer Oa
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- Onuoha C
- Oosterkamp A
- Opoku-Agyeman R
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- Orbegozo Pat
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- Ortega-Vazquez I
- Ortiz N
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- Osei-Nketiah S
- Oshati O
- Oshodi O
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- Osman O
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- Oswald D
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- Othman M
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- Oumer R
- Owen C
- Owusu F
- Owusu F
- Ozben V
- Ozkan Bb
- Ozkan Bb
- Ozkan Bb
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- Paž
- Pabla G
- Pacheco Rda
- Padmore G
- Pagano G
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- Pagnozzi J
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- Palkhi Eya
- Palliyil M
- Palliyil Mm
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- Palma Af
- Paludi Ma
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- Panez Wr
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- Panteli C
- Papageorgiou D
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- Papandrea M
- Papaskarlatos Ia
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- Parmentier B
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- Parseliunas A
- Parthiban S
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- Pascale Mm
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- Pasquali S
- Pastora J
- Pata D
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- Pata F
- Pata F
- Pata F
- Pata F
- Pata F
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- Patoulias I
- Paul M
- Paul S
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- Perera J
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- Perino M
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- Perrotta G
- Pesenti G
- Petrikenas S
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- Pezas T
- Pezas T
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- Picardo A
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- Pineñ
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- Pino W
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- Pluke K
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- Poskus T
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- Pozo Dar
- Prabhudesai A
- Pranevicius R
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- Preckailaite E
- Primavesi F
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- Proctor Vk
- Pronin S
- Prudhomme T
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- Psarianos K
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- Puma Cmh
- Punja V
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- Puttick M
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- Qureshi Au
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- Rasoaherinomenjanahary F
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- Raza A
- Raza I
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- Razmdjou S
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- Razzaque J
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- Recinos G
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- Redota Map
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- Sabour Fa
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- Sahel S
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- Samaniego Cs
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- Schivo D
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- Senanayake Kj
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- Septiem Jg
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- Shahbaz Ar
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- Snyder E
- Sobnach S
- Sodde P
- Soeselo Da
- Sokratous A
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- Soldevila-Verdeguer C
- Soley R
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- Srinivasan R
- Sriram A
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- Stefanopoulos A
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- Summerour V
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- Sundstrom Sm
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- Taiwo A
- Taiwo O
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- Tan Yk
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- Tanase A
- Tang A
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- Tansoker I
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- Thorarinsdottir H
- Thorell A
- Thorell A
- Thorsen K
- Thurairaja R
- Ticona Wa
- Tierney G
- Tilston Tw
- Timothy Ok
- Ting Jrs
- To K
- To K
- Todd O
- Toeema Ag
- Tolba H
- Tolg C
- Tolonen M
- Tolotra Tec
- Tori Sa
- Torrance Hd
- Torrance Hd
- Torres Cpg
- Torres Sg
- Toto Ö
- Tou S
- Townsend D
- Tracy J
- Trompetto M
- Tselos A
- Tshisola Sk
- Tugnoli G
- Tugnoli G
- Tun Ak
- Tun M
- Tun M
- Turati L
- Turati L
- Turkustani S
- Turner M
- Tutino R
- Tverskis Z
- Tyler R
- Tyler R
- Tze Rge
- Tze Rge
- Tzikos G
- Uš
- Ubhi Hk
- Ubiali P
- Ugalde P
- Ukwenya Y
- Uluş
- Ulusahin M
- Upadhyaya V
- Upchurch E
- Urbanavicius L
- Urbonas T
- Urbonas T
- Urniež
- Urniezius Z
- Urquizu Mc
- Usaityte A
- Utter M
- Uzabumwana N
- Vaicius A
- Valcarcel-Saldañ
- Valioulis I
- Van Der Naald N
- Van Duren B
- Van Niekerk M
- Van Straten S
- Varcada M
- Vargas M
- Varkalys K
- Vartanoglu T
- Vartic M
- Vartic M
- Vasquez G
- Vasquez I
- Veen T
- Vega Gmm
- Vega Gmm
- Velá
- Velá
- Velasquez R
- Vella-Baldacchino M
- Venclauskas L
- Vendramin E
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venugopal C
- Verbeek A
- Vergara Alc
- Verjee A
- Vermaas M
- Veronese E
- Viš
- Vianna P
- Vicario E
- Vico Td
- Vida Lc
- Vida Lc
- Vilč
- Villa R
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- Villegas Mi
- Vimalachandran D
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- Violi P
- Vivekanantham S
- Vlachogiorgos A
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- Vth Le
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- Waleed H
- Walker M
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- Waqar M
- Ward Ae
- Ward S
- Warda M
- Warren O
- Warren O
- Warwick Am
- Waterman A
- Watson Nf
- Watts A
- Weber B
- Weber P
- Weber P
- Weinstein Ms
- Werder G
- Wheeler J
- Whewell H
- Whitaker J
- White R
- White T
- Whitehurst K
- Wiborg J
- Widiastini Ta
- Widmer Lw
- Wijayarathna Ls
- Wild Jrl
- Williams E
- Williams G
- Williams O
- Williams O
- Williamson A
- Wilson A
- Wilson L
- Wilson M
- Wilson M
- Wilson Ms
- Wilson Msj
- Wimalge Pmsn
- Winstanley J
- Witherspoon P
- Wogensen F
- Wogensen F
- Wogensen F
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- Wolf B
- Wolf B
- Wondimu S
- Wondoh P
- Wondoh P
- Wong Cs
- Wong Cy
- Wong F
- Wong Hy
- Wood G
- Woodward H
- Worku M
- Worku M
- Worku T
- Wredberg C
- Wright N
- Wright Nj
- Xerri T
- Xerri T
- Yahaya Mt
- Yakubu M
- Yallop L
- Yam Sy
- Yang J
- Yap S
- Yaseen T
- Yaseen Tm
- Yau Jd
- Yavuz Ma
- Ye J
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- Yeo Ls
- Yeung En
- Yeung Mha
- Yifieyeh A
- Yildirim R
- Yip C
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- Yoganathan P
- Yolcu S
- Yong Co
- Yong Gl
- Younis A
- Youssef D
- Youssef H
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- Zachariades Dc
- Zadoroznas A
- Zahran D
- Zakaria E
- Zakaria M
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- Zakir M
- Zalabia Mf
- Zamarin K
- Zammit S
- Zampitis N
- Zani A
- Zani A
- Zani A
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- Zapata F
- Zarb C
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- Zerihun Ab
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- Zidan H
- Zidan H
- Zidan M
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- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zimmermann Ef
- Zohair A
- Zorrilla Cd
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbü
- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Dissolution of quartz, albite, and orthoclase in H2O-saturated haplogranitic melt at 800C and 200 MPa: diffusive transport properties of granitic melts at crustal anatectic conditions.
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 02/02/2006
- Field of study
24 pages, 14 figures, 6 tables.We have conducted experiments on dissolution of quartz, albite, orthoclase, and corundum into H2O-saturated haplogranite melt at
800 C and 200 MPa over a duration of 120–1488 h with the aim of ascertaining the diffusive transport properties of granitic melts at crustal anatectic temperatures. Cylinders of anhydrous starting glass and a single mineral phase (quartz or feldspar) were juxtaposed
along flat and polished surfaces inside gold or platinum capsules with 10 wt % added H2O. Concentration profiles in glass (quenched melt) perpendicular to the mineral–glass interfaces and comparison with relevant phase diagrams suggest that melts at the interface are saturated in the dissolving phases after 384 h, and with longer durations the concentration profiles are controlled only by
diffusion of components in the melt. The evolution of the concentration profiles with time indicates that uncoupled diffusion in the melt takes place along the following four linearly independent directions in oxide composition space: SiO2, Na2O, and K2O axes (Si-, Na-, and K-eigenvectors, respectively), and a direction between the Al2O3, Na2O, and K2O axes (Al-eigenvector), such that the Al/Na molar ratio is equal to that of the bulk melt and the Al/(Na þ K) molar ratio is equal to the equilibrium ASI (¼ mol. Al2O3/[Na2O þ K2O]) of the melt. Experiments in which a glass cylinder was sandwiched between two mineral cylinders—quartz and albite, quartz and K-feldspar, or albite and corundum—tested the validity of the inferred directions of uncoupled diffusion and explored longrange chemical communication in the melt via chemical potential gradients. The application of available solutions to the diffusion equations for the experimental quartz and feldspar dissolution data
provides diffusivities along the directions of the Si-eigenvector and Al-eigenvector of (2 0–2 8) · 10 15 m2/s and (0 6–2 4) ·
10 14 m2/s, respectively. Minimum diffusivities of alkalis
[ (3–9) · 10 11 m2/s] are orders of magnitude greater than
the tetrahedral components of the melt. The information provided here
determines the rate at which crustal anatexis can occur when sufficient
heat is supplied and diffusion is the only mass transport (mixing) process in the melt. The calculated diffusivities imply that a quartzo-feldspathic source rock with initial grain size of 2–3 mm undergoing hydrostatic, H2O-saturated melting at 800 C (infinite heat supply) could produce 20–30 vol. % of
homogeneous melt in less than 1–10 years. Slower diffusion in H2O-undersaturated melts will increase this time frame.Support for this research was provided by National Science Foundation grants EAR-990165, INT-9603199, EAR-9618867, EAR-9625517, EAR-9404658, and a postdoctoral grant to A.A.V. from the Universidad de
Granada, Spain. The Electron Microprobe Laboratory at the University of Oklahoma was created with US DOE grant DE-FG22-87FE1146 and upgraded with NSF grant EAR-9404658 and support from the University of Oklahoma Office of Research Administration. We thank
Don Baker, Alberto Patin˜o Douce, Dennis Geist and an anonymous referee for thorough reviews that improved greatly the consistency and clarity of the manuscript.Peer reviewe
The Allies During the First World War and Paris Peace Conference
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- A Adamthwaite
- A Clark
- A Lentin
- A Sharp
- A Walworth
- AC Pigou
- AJ Mayer
- B Perkins
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- C Seymour
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- CG Dawes
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- DC Watt
- DL George
- DT Jack
- E Goldstein
- E May
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- EE Cummings
- EH Carr
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- EL Jones
- EL Spears
- EM Coffman
- F Stern
- FH Early
- FW Hirst
- G Groot de
- G Hodgson
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- G Sheffield
- GC Conyne
- GP Gooch
- H Barbusse
- H Brands
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- H Hoover
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- KO Morgan
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- M Alexander
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- P Miquel
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- PDL Rochelle
- PM Taylor
- R Henig
- R Prior
- R Skidelsky
- Roosevelt
- S Secerov
- S Shuker
- Skidelsky
- SM Warman
- T Akami
- VI Lenin
- W Heid
- W Reid
- ZAB Zeman
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- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
What is Frugal, What is Innovation? Towards a Theory of Frugal Innovation
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- A H B Monk
- A H Van De Ven
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- A Nijhof
- A S Weinberg
- A Woolridge
- Adam Smith
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- Bloomberg Businessweek
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- C L�vi-Strauss
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- Dec
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- E Abrahamson
- E J Topol
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- E S Clemens
- E Schoenberger
- E Shaw
- Edmond S Morgan
- G Desa
- G George
- H E Aldrich
- H Hargadon
- H Rao
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- Ian Bayley
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- J Utterback
- J W Meyer
- John L Lastovicka
- John Mill
- Joseph A Schumpeter
- K Green
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- L Soete
- M A Peteraf
- M Anderson
- M Arndt
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- M E Porter
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- M Lamont
- M Lounsbury
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- Merriam Webster Dictionary
- N Fligstein
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- N Fligstein
- Oxford Dictionary
- P Collier
- P Dimaggio
- P Foster
- P Geroski
- P J Dimaggio
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- P K Sarmah
- P Polak
- P Westhead
- Pauline Thomas
- Pavithra K Mehta
- R Amit
- R Drazin
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- T Khanna
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- T M Amabile
- U Haque
- V Govindarajan
- Valerie Mendes
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- Von Hippel
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- W G Astley
- W J Abernathy
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- X Fu
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2012
- Field of study
What's in a Name? Would a Rose by Any Other Name Really Smell as Sweet?
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- A Ava
- A Barry
- A Benjamin
- A Frank
- A G Harmon
- A Marcilynn
- A Margaret
- A Oliver
- A Stanley
- Aaron Schwabach
- Adam M Smith
- Adam W Poff
- Alice Riener
- Alicia D Kisling
- Alireza Gharagozlou
- Allison S Woolston
- Amy Christian Mccormick &
- Amy E Black &
- Andrea Monroe
- Andreas F Lowenfield
- Andrew Thornley
- Anita Silvers
- Ann M Markey
- Anne C Levy
- Antoni Vaquer
- Arturo Gandara
- Ashton Hawkins
- B
- B
- B
- B Dr
- B Oliver
- B Snow
- Barry E Adler
- Ben Sones
- Bernard Schwartz
- Blevit Stephen Darren
- Brian Calandra
- Brian Partridge
- C Benne
- C Christopher
- C Christopher
- C Mark
- C Ruth
- C. The Cheshire Cat
- Carol C Brown
- Carol S Steiker
- Carrie Menkel-Meadows
- Carter G Bishop
- Cass R Sunstein
- Cassidy M Flake
- Catherine H Lee
- Chad Brandon
- Charles L Siemon
- Charles S Saphos
- Cheryl A Kettler
- Christina G Dudley
- Christopher J Borgen
- Christopher J Petri
- Christopher T Frederickson
- Cinderella
- Cindy E Faulkner
- Claire Moore Dickerson
- Clark L Lewis
- Clayton R Portell
- Clint Bolick
- Conrad F Meis
- Courtney P Fain
- Current Shabtai Rosenne
- Cynthia A Williams
- D Spencer
- Dan Herber
- Daniel B Rodrigues
- Daniel E Blegen
- Daniel I Smulow
- Daniel J Morrissey
- Daniel S Kleinberger
- David A Elder
- David E Pierce
- David F Bradford
- David Gluck
- David H Taylor
- David L Faigman
- David L Naumann
- David L Wiley
- David M Smolin
- David Ma
- David Manspeizer
- David Rossman
- Debora L Spar
- Dena S Davis
- Denise E Farris
- Devon A
- Donna M Lieutenant Colonel
- Dora W Klein
- Doris Estelle Long
- E Happily
- E S Bradley
- Edward J Mccaffery
- Eliot Walker
- Elizabeth Chamblee Burch
- Elizabeth Garvin &
- Emily Kathryn Tyler
- Eric Engle
- Eric Steiger
- Eric Tucker
- Eric V Hull
- Eugene Cerruti
- F
- F
- Fordham Int
- Fred Eaton
- Fred H Miller
- G
- G Jack
- G Matthew
- Gabrielle Russell
- Gail Sasnett-Stauffer
- Gary Lawson
- Gary Pulsinelli
- Geoffrey L Harrison
- George P Smith
- George W Dent
- Gerald Benjamin
- Gregory E Perry
- H
- H Benjamin
- H Jack
- H Matthew
- H Warren
- Hadley Arkes
- Henderson Harris Weems
- Herald Price Fahringer
- Holger Sch�er
- Hugh Brown
- I Sutton
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- J B James Salzman
- J Dale
- J Dennis
- J Depaul
- J Herwig
- J Mark
- J Steven
- Jack R Tuholske
- Jacqueline St
- James J Tomkovicz
- James K Winn
- Jarod S Gonzalez
- Jason P Luther
- Jay Cherwin
- Jeffrey P Gleason
- Jeffrey W Spaulding
- Jennifer M Lee
- Jennifer Sheppard
- Joan Macleod Heminway
- Joanna K Weinberg
- John F Vargo
- John Stick
- Jose Roberto Juarez
- Joseph T Gasper
- Josephine Liu
- Joshua Ruby
- Judith A Winston
- Julie D Cromer
- Jun-Shik Hwang
- Justin Daraie
- Justin M Lugar
- Kara S Suffredini
- Karen C Burke &
- Karen H Rothenberg
- Karen M Kramer
- Katerina P Weinbuk
- Katherine I Vaughns
- Kathleen L Disanto
- Kevin Brown
- Kevin M O&apos
- Kristin Brandser
- Kyle Friedman
- Kyle S Conway
- L Baylor
- L Camrin
- L Collette
- L Cornell
- L Drake
- L Edward
- L Emory
- L Fordham
- L Hastings
- L Hastings
- L Hastings
- L Hofstra
- L J Emory
- L J Hastings
- L J Hastings
- L J Yale
- L Liesa
- L Mercer
- L Natalie
- L Rutgers
- L Stephen
- L Vsevolod
- L Wayne
- L Willamette
- Laurie A Morin
- Lee Ann Rabe
- Lesley K Mcallister
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- Lisa A Sciallo
- Louise G Trubek
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- M Earl
- M Frank
- M Mears
- M Steven
- Major Daniel
- Marc Mauer
- Marc R Piorier
- Marci Canton Campbell &
- Marcia C Royle
- Margaret F Brinig
- Margaret R Mclean
- Margit Livingston
- Marianne Dellinger
- Marianne M Ibrahim
- Mark E Wojcik
- Martin D Begleiter
- Mary J Dent
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- Maryanne Ryan
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- Minn
- Misha Isaak
- Mitchell Nathanson
- Monica L Mcham
- Morgan Lewis
- Myrna S Raeder
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- Natalia May
- Nathan A Busch
- Neil Batavia
- Neil J Kinkopf
- Nicholas Benson
- Nicole D Mignone
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- P Michel
- Pamela C Chalk
- Patricia A Morse
- Patricia E Dilley
- Patricia E Dilley
- Patrick J Cunningham
- Patrick Mcfadden
- Paul G Mahoney
- Paul L Regan
- Philip G Schrag
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- Phillip E Johnson
- Phyliss Craig-Taylor
- Puja Vadodaria
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- Rachel M White
- Randy S Kravis
- Raymond G Truitt
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- Rhona Lyons
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- Rosanna Cavallaro
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- Sandra Zellmer
- Sarah J Hastings
- Scott Hershovitz
- Seth Gillen
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- Sharon K Sandeen
- Sheila B Scheuerman
- Sherri Lee Keene
- Sidney F Ansbacher
- Sophie Dr
- Staci M Buss
- Stephanie A Gore
- Stephanie J Willbanks
- Stephanie J. Willbanks
- Stephen Daniels
- Stephen Kanter
- Steven Ferrey
- Stuart Lazar
- Sunny Woan
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2013
- Field of study
Causal Inference Regarding Infectious Aetiology of Chronic Conditions: A Systematic Review
- Author
- A Agarwal
- A Bansal
- A Bayram
- A Bostrom
- A Danso-Appiah
- A Geelhaar
- A Kocabas
- A Lazarus
- A Ozdemir
- A Zullo
- AA Akhund
- AB Ryerson
- AC Anand
- AJ Littman
- AJ Littman
- AM Lowe
- AR Berliner
- AS Penrose
- AV Nersesov
- B Bodaghi
- B Peters
- B Sharifi-Mood
- BJ Ferguson
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- C Kurihara
- C Romano Carratelli
- C Saltini
- CA Kiire
- CC Lee
- CG Mabanta
- CH King
- CM Bruno
- CY Tong
- D Sorrentino
- D Totin
- DL Costa
- E Aygenc
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- E Dosa
- E Fassio
- E Mahler
- EB Norton
- Emma Medin
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- F Fabrizi
- FA Botoni
- FJ Monteon
- G Passarino
- G Salles
- G Zeng
- GE Miller
- GE Thwaites
- GV Papatheodoridis
- H Nakamura
- H Ohata
- H Schunemann
- HC Jha
- I Adetifa
- I Ahmed
- I Soerjomataram
- IH Galadari
- J George
- J Koshiol
- J Rupp
- J Sellner
- JA Ake
- JA Marin-Neto
- JA Rassi
- Jan C. Semenza
- JC Semenza
- JCH Van Der Hilst
- JD Carter
- JK Louie
- JN Krieger
- K Crothers
- K Kulthanan
- K Thakkar
- L Li
- L Rambout
- LA Sechi
- LR Medeiros
- LY Chang
- M Abello
- M Haubitz
- M Ramos-Casals
- M Sakurane
- M Yariktas
- MA Salome
- MB Zonta
- MC Savas
- ME Colpan
- MH Lee
- Michael Bouchard
- MP Toscano
- MSP Ladeira
- N Bozbuga
- N Jindal
- N Mehdi
- N Mete
- N Muhlberger
- N Unsworth
- N Yilmaz
- ND Gross
- ND Madala
- NHN Hazlina
- NR Rosenberg
- O Bestard
- P Gaig
- PB Boulos
- PC Chan
- PK Ramdial
- PPA Reyes
- PV Wackermann
- R Mahnel
- R Perez-Fuentes
- RA Ferrand
- RD Serano
- RJ Martin
- RM Granich
- RM Wadowsky
- S Adinarayanan
- S Dissanayake
- S ElSaadany
- S Georgala
- S Handa
- S Hellmig
- S Jeansson
- S Karande
- S Kiechl
- S Kuk
- S Leconte
- S Maqsood
- S Pandya
- S Vong
- SL Knobler
- Sofia Orrskog
- SS Signorelli
- ST Donta
- ST Donta
- Svetla Tsolova
- T Inaba
- T Merlin
- T Rekand
- T Suzuki
- T Uscategui
- TAD Theodoropoulos
- TH Jaing
- TM Welzel
- TR Morgan
- V Chieux
- V Skerk
- VH Chu
- VI Reshetnyak
- W Rudnicka
- Y Nagao
- YF Wang
- YH Ni
- YQ Feng
- Z Li
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study