150 research outputs found
Evaluating the ability of citizen scientists to identify bumblebee (Bombus) species
Citizen science is an increasingly popular way of engaging volunteers in the collection of scientific data. Despite this, data quality remains a concern and there is little published evidence about the accuracy of records generated by citizen scientists. Here we compare data generated by two British citizen science projects, Blooms for Bees and BeeWatch, to determine the ability of volunteer recorders to identify bumblebee (Bombus) species. We assessed recorders' identification ability in two ways-as recorder accuracy (the proportion of expert-verified records correctly identified by recorders) and recorder success (the proportion of recorder-submitted identifications confirmed correct by verifiers). Recorder identification ability was low (<50% accuracy; <60% success), despite access to project specific bumblebee identification materials. Identification ability varied significantly depending on bumblebee species, with recorders most able to correctly identify species with distinct appearances. Blooms for Bees recorders (largely recruited from the gardening community) were markedly less able to identify bumblebees than BeeWatch recorders (largely individuals with a more specific interest in bumblebees). Within both projects, recorders demonstrated an improvement in identification ability over time. Here we demonstrate and quantify the essential role of expert verification within citizen science projects, and highlight where resources could be strengthened to improve recorder ability
Reducing space-time to binary information
We present a new description of discrete space-time in 1+1 dimensions in terms of a set of elementary geometrical units that represent its independent classical degrees of freedom. This is achieved by means of a binary encoding that is ergodic in the class of space-time manifolds respecting coordinate invariance of general relativity. Space-time fluctuations can be represented in a classical lattice gas model whose Boltzmann weights are constructed with the discretized form of the Einstein–Hilbert action. Within this framework, it is possible to compute basic quantities such as the Ricci curvature tensor and the Einstein equations, and to evaluate the path integral of discrete gravity. The description as a lattice gas model also provides a novel way of quantization and, at the same time, to quantum simulation of fluctuating space-time
Mitigation-driven translocations: are we moving wildlife in the right direction?
Despite rapid growth in the field of reintroduction biology, many lessons learned from scientific research are not being applied to translocations initiated when human land-use conflicts with persistence of a species. Mitigation-driven translocations outnumber and receive better funding than science-based conservation translocations worldwide, yet their conservation benefit is unclear. As mitigation releases are economically motivated, outcomes may diverge greatly from releases designed to serve the biological needs of species. Translocation as a regulatory tool may be ill-fitted to biologically mitigate environmental damage wrought by development. Evidence suggests that many mitigation-driven translocations fail, though application of scientific principles and best-practices could likely increase success. Furthermore, lack of transparency and documentation of outcomes hinder efforts to understand the scope of the problem. If mitigation-driven translocations continue unabated as a part of the growing billion-dollar ecological consulting industry, it is imperative that the scale and effects of these releases are reported and evaluated
Exploring the role of smartphone technology for citizen science in agriculture
Citizen science is the involvement of citizens, such as farmers, in the research process. Citizen science has become increasingly popular recently, supported by the proliferation of mobile communication technologies such as smartphones. However, citizen science methodologies have not yet been widely adopted in agricultural research. Here, we conducted an online survey with 57 British and French farmers in 2014. We investigated (1) farmer ownership and use of smartphone technologies, (2) farmer use of farm-specific management apps, and (3) farmer interest and willingness to participate in agricultural citizen science projects. Our results show that 89 % respondents owned a smartphone, 84 % used it for farm management, and 72 % used it on a daily basis. Fifty-nine percent engaged with farm-specific apps, using on average four apps. Ninety-three percent respondents agreed that citizen science was a useful methodology for data collection, 93 % for real-time monitoring, 83 % for identification of research questions, 72 % for experimental work, and 72 % for wildlife recording. Farmers also showed strong interest to participate in citizen science projects, often willing to commit substantial amounts of time. For example, 54 % of British respondents were willing to participate in farmland wildlife recording once a week or monthly. Although financial support was not always regarded as necessary, experimental work was the most likely activity for which respondents thought financial support would be essential. Overall, this is the first study to quantify and explore farmers' use of smartphones for farm management, and document strong support for farm-based citizen science projects. (Résumé d'auteur
The CentriMag Centrifugal Blood Pump as a Benchmark for In Vitro Testing of Hemocompatibility in Implantable Ventricular Assist Devices
Abstract: Implantable ventricular assist devices (VADs) have proven efficient in advanced heart failure patients as a bridge-to-transplant or destination therapy. However, VAD usage often leads to infection, bleeding, and throm-bosis, side effects attributable to the damage to blood cells and plasma proteins. Measuring hemolysis alone does not provide sufficient information to understand total blood damage, and research exploring the impact of cur-rently available pumps on a wider range of blood cell types and plasma proteins such as von Willebrand factor (vWF) is required to further our understanding of safer pump design. The extracorporeal CentriMag (Thoratec Corporation, Pleasanton, CA, USA) has a hemolysis profile within published standards of normalized index of hemolysis levels of less than 0.01 g/100 L at 100 mm Hg bu
Genomic diversity of Escherichia coli isolates from non-human primates in the Gambia
Increasing contact between humans and non-human primates provides an opportunity for the transfer of potential pathogens or antimicrobial resistance between host species. We have investigated genomic diversity and antimicrobial resistance in Escherichia coli isolates from four species of non-human primates in the Gambia: Papio papio (n=22), Chlorocebus sabaeus (n=14), Piliocolobus badius (n=6) and Erythrocebus patas (n=1). We performed Illumina whole-genome sequencing on 101 isolates from 43 stools, followed by nanopore long-read sequencing on 11 isolates. We identified 43 sequence types (STs) by the Achtman scheme (ten of which are novel), spanning five of the eight known phylogroups of E. coli. The majority of simian isolates belong to phylogroup B2 - characterized by strains that cause human extraintestinal infections - and encode factors associated with extraintestinal disease. A subset of the B2 strains (ST73, ST681 and ST127) carry the pks genomic island, which encodes colibactin, a genotoxin associated with colorectal cancer. We found little antimicrobial resistance and only one example of multi-drug resistance among the simian isolates. Hierarchical clustering showed that simian isolates from ST442 and ST349 are closely related to isolates recovered from human clinical cases (differences in 50 and 7 alleles, respectively), suggesting recent exchange between the two host species. Conversely, simian isolates from ST73, ST681 and ST127 were distinct from human isolates, while five simian isolates belong to unique core-genome ST complexes - indicating novel diversity specific to the primate niche. Our results are of planetary health importance, considering the increasing contact between humans and wild non-human primates
An assessment of bumblebee (Bombus spp) land use and floral preference in UK gardens and allotments cultivated for food
An outbreak of pneumococcal meningitis among older children (≥5 years) and adults after the implementation of an infant vaccination programme with the 13-valent pneumococcal conjugate vaccine in Ghana.
BACKGROUND: An outbreak of pneumococcal meningitis among non-infant children and adults occurred in the Brong-Ahafo region of Ghana between December 2015 and April 2016 despite the recent nationwide implementation of a vaccination programme for infants with the 13-valent pneumococcal conjugate vaccine (PCV13). METHODS: Cerebrospinal fluid (CSF) specimens were collected from patients with suspected meningitis in the Brong-Ahafo region. CSF specimens were subjected to Gram staining, culture and rapid antigen testing. Quantitative PCR was performed to identify pneumococcus, meningococcus and Haemophilus influenzae. Latex agglutination and molecular serotyping were performed on samples. Antibiogram and whole genome sequencing were performed on pneumococcal isolates. RESULTS: Eight hundred eighty six patients were reported with suspected meningitis in the Brong-Ahafo region during the period of the outbreak. In the epicenter district, the prevalence was as high as 363 suspected cases per 100,000 people. Over 95Â % of suspected cases occurred in non-infant children and adults, with a median age of 20Â years. Bacterial meningitis was confirmed in just under a quarter of CSF specimens tested. Pneumococcus, meningococcus and Group B Streptococcus accounted for 77Â %, 22Â % and 1Â % of confirmed cases respectively. The vast majority of serotyped pneumococci (80Â %) belonged to serotype 1. Most of the pneumococcal isolates tested were susceptible to a broad range of antibiotics, with the exception of two pneumococcal serotype 1 strains that were resistant to both penicillin and trimethoprim-sulfamethoxazole. All sequenced pneumococcal serotype 1 strains belong to Sequence Type (ST) 303 in the hypervirulent ST217 clonal complex. CONCLUSION: The occurrence of a pneumococcal serotype 1 meningitis outbreak three years after the introduction of PCV13 is alarming and calls for strengthening of meningitis surveillance and a re-evaluation of the current vaccination programme in high risk countries
Belimumab in kidney transplantation:an experimental medicine, randomised, placebo-controlled phase 2 trial
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