337 research outputs found
Comercio marítimo. Comparativa entre los puertos de España y Bélgica
Maritime trade represents over 80% of global trade. This increasing trend has led to higher collection, storage, and distribution needs. On occasions, it has caused jamming of goods in some ports. This is the reason why the importance of maritime trade is highlighted. The main objective of this Final Degree Project is to find points of improvement in Spanish ports. For this purpose, a comparative study is made between the main Spanish and Belgian ports. The comparison has been carried out through a SWOT analysis that can contribute to improving the competitiveness of our ports.El comercio marítimo representa más del 80% del comercio mundial. Esta tendencia creciente ha provocado un aumento de las necesidades de recogida, almacenamiento y distribución, provocando en ocasiones atascos de mercancías en algunos puertos. Es por ello que se resalta la importancia del comercio marítimo a nivel mundial. El objetivo principal de este Trabajo de Fin de Grado es encontrar puntos de mejora en los puertos españoles. Para ello, se elabora un estudio comparativo entre los principales puertos españoles y los principales puertos belgas. La comparativa se ha llevado a cabo a través de un análisis DAFO que pueda contribuir a mejorar la competitividad de nuestros puertos.<br /
Los adhesivos empleados en el entelado de carteles modernos. Uso de la Espectrometría de Masas de Ionización/Desorción por Láser asistida por Matriz y analizador de Tiempo de Vuelo (MALDI-TOF-MS) para la identificación de éteres de celulosa
"XVIII Congreso Internacional de Conservación y Restauración de Bienes Culturales - 18th International Meeting on Heritage Conservation", Granada 9 al 11 novembre de 201
Identification of cellulose ethers in cultural heritage by means of MALDI-TOF-MS
Cellulose ethers used as adhesives in heritage conservation treatments have been successfully identified by means of MALDI-TOF-MS, a technique non-previously applied for this purpose in cultural assets. This is of relevant importance for long-term conservation, as discrimination among the diverse types of cellulose ethers that may have been applied to an asset during conservation treatments is essential in order to guarantee stability of artworks. The proposed method also allows discrimination among these adhesives spread on paper-based artworks, where cellulose ethers have been extensively utilized for many years, overcoming interferences usually occurred due to the cellulosic nature of both adhesive and support. Successful results have been obtained from mock-ups and small samples of paper-based original artworks with usual low concentrations of adhesive. FTIR and NMR have been used as complementary analytical techniques
High performance lattice reduction on heterogeneous computing platform
The final publication is available at Springer via http://dx.doi.org/10.1007/s11227-014-1201-2The lattice reduction (LR) technique has become very important in many engineering fields. However, its high complexity makes difficult its use in real-time applications, especially in applications that deal with large matrices. As a solution, the modified block LLL (MB-LLL) algorithm was introduced, where several levels of parallelism were exploited: (a) fine-grained parallelism was achieved through the cost-reduced all-swap LLL (CR-AS-LLL) algorithm introduced together with the MB-LLL by Jzsa et al. (Proceedings of the tenth international symposium on wireless communication systems, 2013) and (b) coarse-grained parallelism was achieved by applying the block-reduction concept presented by Wetzel (Algorithmic number theory. Springer, New York, pp 323-337, 1998). In this paper, we present the cost-reduced MB-LLL (CR-MB-LLL) algorithm, which allows to significantly reduce the computational complexity of the MB-LLL by allowing the relaxation of the first LLL condition while executing the LR of submatrices, resulting in the delay of the Gram-Schmidt coefficients update and by using less costly procedures during the boundary checks. The effects of complexity reduction and implementation details are analyzed and discussed for several architectures. A mapping of the CR-MB-LLL on a heterogeneous platform is proposed and it is compared with implementations running on a dynamic parallelism enabled GPU and a multi-core CPU. The mapping on the architecture proposed allows a dynamic scheduling of kernels where the overhead introduced is hidden by the use of several CUDA streams. Results show that the execution time of the CR-MB-LLL algorithm on the heterogeneous platform outperforms the multi-core CPU and it is more efficient than the CR-AS-LLL algorithm in case of large matrices.Financial support for this study was provided by grants TAMOP-4.2.1./B-11/2/KMR-2011-0002, TAMOP-4.2.2/B-10/1-2010-0014 from the Pazmany Peter Catholic University, European Union ERDF, Spanish Government through TEC2012-38142-C04-01 project and Generalitat Valenciana through PROMETEO/2009/013 project.Jozsa, CM.; Domene Oltra, F.; Vidal Maciá, AM.; Piñero Sipán, MG.; González Salvador, A. (2014). High performance lattice reduction on heterogeneous computing platform. Journal of Supercomputing. 70(2):772-785. https://doi.org/10.1007/s11227-014-1201-2S772785702Józsa CM, Domene F, Piñero G, González A, Vidal AM (2013) Efficient GPU implementation of lattice-reduction-aided multiuser precoding. In: Proceedings of the tenth international symposium on wireless communication systems (ISWCS 2013)Wetzel S (1998) An efficient parallel block-reduction algorithm. In: Buhler JP (ed) Algorithmic number theory. Lecture notes in computer science, vol 1423. Springer, Berlin, Heidelberg, pp 323–337Wubben D, Seethaler D, Jaldén J, Matz G (2011) Lattice reduction. Signal Process Mag IEEE 28(3):70–91Lenstra AK, Lenstra HW, Lovász L (1982) Factoring polynomials with rational coefficients. Math Ann 261(4):515–534Bremner MR (2012) Lattice basis reduction: an introduction to the LLL algorithm and its applications. CRC Press, USAWu D, Eilert J, Liu D (2008) A programmable lattice-reduction aided detector for MIMO-OFDMA. In: 4th IEEE international conference on circuits and systems for communications (ICCSC 2008), pp 293–297Barbero LG, Milliner DL, Ratnarajah T, Barry JR, Cowan C (2009) Rapid prototyping of Clarkson’s lattice reduction for MIMO detection. In: IEEE international conference on communications (ICC’09), pp 1–5Gestner B, Zhang W, Ma X, Anderson D (2011) Lattice reduction for MIMO detection: from theoretical analysis to hardware realization. IEEE Trans Circ Syst I Regul Pap 58(4):813–826Shabany M, Youssef A, Gulak G (2013) High-throughput 0.13- \upmu μ m CMOS lattice reduction core supporting 880 Mb/s detection. IEEE Trans Very Large Scale Integr (VLSI) Syst 21(5):848–861Luo Y, Qiao S (2011) A parallel LLL algorithm. In: Proceedings of the fourth international C* conference on computer science and software engineering, pp 93–101Backes W, Wetzel S (2011) Parallel lattice basis reduction—the road to many-core. In: IEEE 13th international conference on high performance computing and communications (HPCC)Ahmad U, Amin A, Li M, Pollin S, Van der Perre L, Catthoor F (2011) Scalable block-based parallel lattice reduction algorithm for an SDR baseband processor. In: 2011 IEEE international conference on communications (ICC)Villard G (1992) Parallel lattice basis reduction. In: Papers from the international symposium on symbolic and algebraic computation (ISSAC’92). ACM, New YorkDomene F, Józsa CM, Vidal AM, Piñero G, Gonzalez A (2013) Performance analysis of a parallel lattice reduction algorithm on many-core architectures. In: Proceedings of the 13th international conference on computational and mathematical methods in science and engineeringGestner B, Zhang W, Ma X, Anderson DV (2008) VLSI implementation of a lattice reduction algorithm for low-complexity equalization. In: 4th IEEE international conference on circuits and systems for communications (ICCSC 2008), pp 643–647Burg A, Seethaler D, Matz G (2007) VLSI implementation of a lattice-reduction algorithm for multi-antenna broadcast precoding. In: IEEE international symposium on circuits and systems (ISCAS 2007), pp 673–676Bruderer L, Studer C, Wenk M, Seethaler D, Burg A (2010) VLSI implementation of a low-complexity LLL lattice reduction algorithm for MIMO detection. In: Proceedings of 2010 IEEE international symposium on circuits and systems (ISCAS
Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis.
BACKGROUND: Lipids are an important and highly diverse class of molecules having structural, energy storage and signaling roles. Modern analytical technologies afford screening of many lipid molecular species in parallel. One of the biggest challenges of lipidomics is elucidation of important pathobiological phenomena from the integration of the large amounts of new data becoming available. RESULTS: We present computational and informatics approaches to study lipid molecular profiles in the context of known metabolic pathways and established pathophysiological responses, utilizing information obtained from modern analytical technologies. In order to facilitate identification of lipids, we compute the scaffold of theoretically possible lipids based on known lipid building blocks such as polar head groups and fatty acids. Each compound entry is linked to the available information on lipid pathways and contains the information that can be utilized for its automated identification from high-throughput UPLC/MS-based lipidomics experiments. The utility of our approach is demonstrated by its application to the lipidomic characterization of the fatty liver of the genetically obese insulin resistant ob/ob mouse model. We investigate the changes of correlation structure of the lipidome using multivariate analysis, as well as reconstruct the pathways for specific molecular species of interest using available lipidomic and gene expression data. CONCLUSION: The methodology presented herein facilitates identification and interpretation of high-throughput lipidomics data. In the context of the ob/ob mouse liver profiling, we have identified the parallel associations between the elevated triacylglycerol levels and the ceramides, as well as the putative activated ceramide-synthesis pathways.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
Fast block QR update in digital signal processing
[EN] The processing of digital sound signals often requires the computation of the QR factorization of a rectangular system matrix. However, sometimes, only a given (and probably small) part of the system matrix varies from the current sample to the next one. We exploit this fact to reuse some computations carried out to process the former sample in order to save execution time in the processing of the current sample. These savings can be critical for real-time applications running on low power consumption devices with high mobility. In addition, we propose a simple out-of-order task-parallel algorithm for the QR factorization using OpenMP that exploits the multicore capability of modern processors. Furthermore, in the presence of a Graphics Processing Unit (GPU) in the system, our algorithm is able to off-load some tasks to the GPU to accelerate the computation on these hardware devices.This work was supported by the Spanish Ministry of Economy and Competitiveness under MINECO and FEDER projects TEC2015-67387-C4-1-R and TIN2014-53495-R; and the Generalitat Valenciana PROMETEOII/2014/003Alventosa, FJ.; Alonso-Jordá, P.; Vidal Maciá, AM.; Piñero, G.; Quintana-Ortí, ES. (2019). Fast block QR update in digital signal processing. The Journal of Supercomputing. 75(3):1051-1064. https://doi.org/10.1007/s11227-018-2298-5S10511064753Augonnet C, Thibault S, Namyst R (2010) StarPU: a runtime system for scheduling tasks over accelerator-based multicore machines. Research Report RR-7240, INRIAButtari A, Langou J, Kurzak J, Dongarra J (2008) Parallel tiled QR factorization for multicore architectures. Concurr Comput Pract Exp 20(13):1573–1590Buttari A, Langou J, Kurzak J, Dongarra J (2009) A class of parallel tiled linear algebra algorithms for multicore architectures. Parallel Comput 35(1):38–53Chan E, Quintana-Ortí ES, Quintana-Ortí G, van de Geijn R (2007) Supermatrix out-of-order scheduling of matrix operations for smp and multi-core architectures. In: Proceedings of the Nineteenth Annual ACM Symposium on Parallel Algorithms and Architectures, SPAA ’07. ACM, New York, pp 116–125Chan E, Van Zee FG, Quintana-Ortí ES, Quintana-Ortí G, De Van Geijn R (2007) Satisfying your dependencies with supermatrix. In: Proceedings—2007 IEEE International Conference on Cluster Computing, CLUSTER 2007. pp 91–99Chan E, Van Zee FG, Bientinesi P, Quintana-Ortí ES, Quintana-Ortí G, van de Geijn RA (2008) Supermatrix: a multithreaded runtime scheduling system for algorithms-by-blocks. In: Chatterjee S, Scott ML (eds) PPOPP. ACM, New york, pp 123–132Golub GH, Van Loan CF (2013) Matrix computations. Johns Hopkins Studies in the Mathematical Sciences. Johns Hopkins University Press, BaltimoreGunter BC, van de Geijn RA (2005) Parallel out-of-core computation and updating the QR factorization. ACM Trans Math Softw 31(1):60–78Joffrain T, Quintana-Ortí ES, van de Geijn RA (2004) Rapid development of high-performance out-of-core solvers. In: Applied Parallel Computing, State of the Art in Scientific Computing, 7th International Workshop, PARA 2004, Lyngby, Denmark, June 20–23, 2004, revised selected papers. pp 413–422NVIDIA. The cuBLAS library. http://docs.nvidia.com/cuda/cublas . Accessed May 2017Openblas. http://www.openblas.net . Accessed May 2017Quintana-Ortí G, Quintana-Ortí ES, Van De Geijn RA, Van Zee FG, Chan E (2009) Programming matrix algorithms-by-blocks for thread-level parallelism. ACM Trans Math Softw 36(3):14:1–14:26The OmpSs Programming Model. https://pm.bsc.es/ompss . Accessed May 2017Wende F, Steinke T, Cordes F (2014) Multi-threaded kernel offloading to gpgpu using hyper-q on kepler architecture. Technical Report 14-19, ZIB, Takustr.7, 14195 Berli
Estudio descriptivo sobre el recuerdo del paciente tras la comunicación del diagnóstico y del pronóstico en oncología
The communication doctor – patient plays a fundamental role in their relationship. Bad communication can imply a negative influence between patient and his family. The aim of this work is to obtain better insight in the process of the information that is contributed by the medical oncologist and to check whether the patients remembers this information after fifteen days. The information we present corresponds with the second phase of the “descriptive study on the process of communicating the diagnosis and the prognosis in oncology”. Cohort consisted in 71 cancer patients, who remembered the initial interview and performed a second one. The results obtained show that data collection is depending on the complexity of the transmitted information as well as of its emotional impact; which means that, the simpler and the more emotional impact, better to remember. Therefore this information supports the idea that communication is an evolutionary and continuing process, and is not limited to certain situations, being able to attend the needs both of the patient and his family, facilitating the patient a better adaptation to the oncological disease.La comunicación juega un papel fundamental en la relación médico-paciente. La mala comunicación así mismo, puede llegar a tener una influencia negativa en el paciente y sus familiares. El objetivo de este trabajo es profundizar en el proceso de información aportada por el médico oncólogo y el recuerdo que mantiene el paciente de dicha información transcurridos quince días. Los datos que presentamos se corresponden con la segunda fase del “estudio descriptivo sobre el proceso de comunicar el diagnóstico y el pronóstico en oncología”. La muestra esta formada por 71 pacientes, todos ellos realizaron una segunda entrevista y recordaban la entrevista inicial. Los resultados obtenidos muestran que el recuerdo está en función de la complejidad de la información transmitida así como del impacto emocional de la misma; es decir, a mayor simplicidad y mayor impacto emocional, mejor recuerdo. Por tanto estos datos apoyan la necesidad de que la comunicación sea un proceso evolutivo, y continuado, y no se reduzca a un momento puntual, atendiéndose a las necesidades tanto del paciente como de sus familiares, facilitándose así una mejor adaptación al proceso oncológico
Diagnóstico de los Estados Financieros del Mantaoro Hotelera Manta S.A.: periodo 2019-2020
El presente trabajo, tiene por finalidad efectuar un diagnóstico sobre la información contenida en los Estados Financieros del Mantaoro Hotelera Manta S.A. Para lo cual, se ha considerado como periodo de evaluación los años 2019 – 2020; sobre los cuales se realiza el análisis de la información financiera. Como parte de la metodología utilizada, se aplica el análisis vertical y horizontal respectivamente a un total de treinta cuentas, contenido en tres grupos, activos, pasivos y patrimonio. De esta manera y mediante la ejecución de ratios financieros, se determinó la liquidez, solvencia y endeudamiento que presenta la empresa al término de los periodos evaluados. Fundamentando que el diagnóstico económico de una empresa se basa en la revisión inicial de la situación financiera de esta, apoyada en el cálculo objetivo de indicadores claves y el equilibrio del progreso de la cuenta, que permiten conocer el buen o mal funcionamiento que esta ha tenido en periodos determinados
Monitoring of Schmallenberg virus in Spanish wild artiodactyls, 2006-2015
Schmallenberg disease is an emerging disease that affects domestic and wild ruminants in Europe. An epidemiological survey was carried out to assess exposure to Schmallenberg virus (SBV) in wild artiodactyls in Spain between 2006 and 2015. A total of 1751 sera from wild artiodactyls, including 1066 red deer, 304 fallow deer, 192 mouflon, 109 wild boar, 49 roe deer and 31 Spanish ibex were tested for antibodies against SBV by ELISA and confirmed by virus neutralization test. SBV was not detected between the 2006/2007 and the 2010/2011 hunting seasons. Overall seroprevalence (including samples collected between the 2011/2012 and 2014/2015 hunting seasons) was 14.6% (160/1099; 95%CI: 12.7-16.6). Mean SBV seroprevalence was 13.3±2.6% in red deer, 23.9±4.2% in fallow deer, 16.4±6.1% in mouflon and 2.8±3.1% in wild boar. No antibodies against SBV were found in roe deer or Spanish ibex. The presence of SBV RNA was confirmed in three of 255 (1.2%) spleen samples from wild ruminants analysed by rRT-PCR. In a multivariate mixed-effects logistic regression model, the main risk factors associated with SBV seroprevalence were: species (fallow deer, red deer and mouflon), age (adults) and interactions between hunting areas of more than 1000 hectares and hunting season (2012/2013, 2013/2014 and 2014/2015). The hypothesis of endemic circulation of SBV in the last few years is supported by the detection of SBV RNA in animals sampled in 2011 and 2015, as well as antibodies detected at low level in juveniles in 2012, 2013 and 2014. The results indicate that SBV circulated in wild ruminant populations in Spain during the same period when the virus was first reported in northern Europe, and at least five months before the first case was officially reported in livestock in Spain
Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass.
BACKGROUND: The progression towards type 2 diabetes depends on the allostatic response of pancreatic beta cells to synthesise and secrete enough insulin to compensate for insulin resistance. The endocrine pancreas is a plastic tissue able to expand or regress in response to the requirements imposed by physiological and pathophysiological states associated to insulin resistance such as pregnancy, obesity or ageing, but the mechanisms mediating beta cell mass expansion in these scenarios are not well defined. We have recently shown that ob/ob mice with genetic ablation of PPARγ2, a mouse model known as the POKO mouse failed to expand its beta cell mass. This phenotype contrasted with the appropriate expansion of the beta cell mass observed in their obese littermate ob/ob mice. Thus, comparison of these models islets particularly at early ages could provide some new insights on early PPARγ dependent transcriptional responses involved in the process of beta cell mass expansion RESULTS: Here we have investigated PPARγ dependent transcriptional responses occurring during the early stages of beta cell adaptation to insulin resistance in wild type, ob/ob, PPARγ2 KO and POKO mice. We have identified genes known to regulate both the rate of proliferation and the survival signals of beta cells. Moreover we have also identified new pathways induced in ob/ob islets that remained unchanged in POKO islets, suggesting an important role for PPARγ in maintenance/activation of mechanisms essential for the continued function of the beta cell. CONCLUSIONS: Our data suggest that the expansion of beta cell mass observed in ob/ob islets is associated with the activation of an immune response that fails to occur in POKO islets. We have also indentified other PPARγ dependent differentially regulated pathways including cholesterol biosynthesis, apoptosis through TGF-β signaling and decreased oxidative phosphorylation.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
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