Análisis de la satisfacción vital del estudiantado universitario a través de factores socioemocionales

This study attempts to provide evidence of the relationship between emotional intelligence and resilience, with optimism vs. pessimism as mediating variables of life satisfaction. The sample included 403 university students. The average age was 20.86 (SD= 2.56). In relation to gender, 84.61% were female and 15.39% were male participants. Information was collected by means of four tools: Wong Law Emotional Intelligence Scale (WLEIS-S), Resilience Scale (RS-14), Life Orientation Test Scale Revised (LOT-R) and Satisfaction with Life Scale (SWLS). Regarding the association between Emotional Intelligence and Resilience, a statistically significant relationship was observed. Besides, positive relationships were found between optimism and satisfaction with life; while a negative association with pessimism was noted. The results indicate that students with a high level of emotional intelligence and resilience have higher scores in optimism and life satisfaction. Moreover, the structural equation model showed that Emotional Intelligence and resilience are able to predict higher life satisfaction directly (β= .19, and β= .26, respectively), but they may also mediate through optimism. This mediation effect did not appear with the pessimism factor. Finally, the practical implications of this study underline the need to promote emotional intelligence and resilience education programmes to improve personal well-being.Este estudio trata de aportar pruebas sobre la relación entre la inteligencia emocional y la resiliencia, con el optimismo frente al pesimismo como variable mediadora sobre la satisfacción vital. La muestra incluyó 403 estudiantes universitarios. La edad media es de 20.86 años (SD= 2.56). En relación con el género, el 84.61% eran mujeres y el 15.39% eran hombres. La información se recogió mediante cuatro instrumentos: Escala de Inteligencia Emocional de Wong Law (WLEIS-S), Escala de Resiliencia (RS-14), Escala de Test de Orientación Vital Revisada (LOT-R) y Escala de Satisfacción con la Vida (SWLS). En cuanto a la asociación entre la Inteligencia Emocional y la Resiliencia, se encontró una relación estadísticamente significativa. Asimismo, se encontraron relaciones positivas entre el optimismo y la satisfacción con la vida; y negativas con el pesimismo. Los resultados indican que los estudiantes con un alto nivel de inteligencia emocional y resiliencia tienen puntuaciones más altas en optimismo y satisfacción con la vida. Además, el modelo de ecuaciones estructurales mostró que la inteligencia emocional y la resiliencia son capaces de predecir una mayor satisfacción con la vida (β= .19, y β= .26, respectivamente), pero, además, también pueden mediar a través del optimismo. Este efecto de mediación no apareció con el factor pesimismo. Finalmente, las implicaciones prácticas de este estudio subrayan la necesidad de promover programas de educación en inteligencia emocional y resiliencia para mejorar el bienestar personal.Research Plan of the University of Granada. Title of the project “Pre-service Teacher professionalisation in social emotional skills in the post-pandemic period” (Grant ID: PPJIA2021-28

Analysis of the Pre-Service Teachers’ Academic Stress Based on Their Self-Concept and Personality

Self-concept is a key factor in any teaching–learning process in pre-service teachers. However, it could be negatively affected by academic stress, which is constituted by stressors, stress symptoms, and coping strategies. The aim of the study was to determine the relationship between academic stress and self-concept in this population. This was a descriptive, correlational, and crosssectional study. The sample consisted of 1020 university students in education degrees. In relation to sex, it was found that 75.78% were women and 24.21% were men. The following instruments were used: Self-concept Form 5 (AF-5), the Big Five Inventory-44 (BFI-44), and the SISCO Inventory of Academic Stress. The results indicated that academic stress increases and self-concept decreases as studies progress; likewise, most of the students perceived high levels of stress. It was concluded that academic stress is inversely related to self-concept in pre-service teachers, a fact that should be taken into account in their initial training. Social-emotional factors and neuroticism have a decisive influence on the future teachers’ academic stress

Rapid test for identification of a highly transmissible Mycobacterium tuberculosis beijing strain of sub-Saharan origin

The development of a rapid test to identify Mycobacterium tuberculosis Beijing isolates and specifically strain GC1237, coming from a sub-Saharan country, is needed due to its alarming wide spread on Gran Canaria Island (Spain). A rapid test that detects IS6110 present between dnaA and dnaN in the Beijing strains and in a specific site for GC1237 (Rv2180c) has been developed. This test would be a useful tool in the surveillance of subsequent cases

GuíaSalud, el organismo del Sistema Nacional de Salud para impulsar la práctica basada en la evidencia

VIII Congreso Iberoamericano de Nutrición. ¿Nutrición basada en la videncia o en la evidencia? ¿Qué es GuíaSalud? GuíaSalud es un organismo del Sistema Nacional de Salud (SNS) creado en el 2002 por iniciativa de la Comunidad Autónoma de Aragón y la Fundación Salud Innovación y Sociedad, y adoptado en 2003 por el Consejo Interterritorial como instrumento para mejorar la calidad de la atención sanitaria en el SNS. A nivel organizativo, consta de un Consejo Ejecutivo en el que participan los Departamentos y Consejerías de Salud de las 17 Comunidades Autónomas y el Ministerio de Sanidad, un Comité Científico conformado por 13 profesionales de reconocido prestigio por su labor científicotécnica en relación con las Guías de Práctica Clínica, la Secretaría ostentada por el Instituto Aragonés de Ciencias de la Salud, y una Red de Colaboradores/as que sirve de apoyo para llevar a cabo las diferentes líneas de actuación. GuíaSalud tiene por misión general potenciar la oferta de recursos, servicios y productos basados en la evidencia científica para apoyar la toma de decisión de los profesionales y de los pacientes en el Sistema Nacional de Salud (SNS), así como impulsar la creación de redes de colaboradores y la cooperación entre entidades relacionadas con las GPC y la Medicina Basada en la Evidencia (MBE). ..

Actualización de la batería estándar y batería ampliada de pruebas alérgicas de contacto por el Grupo Español de Investigación en Dermatitis de Contacto y Alergia Cutánea (GEIDAC)

After the meeting held by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC) back in October 2021, changes were suggested to the Spanish Standard Series patch testing. Hydroxyethyl methacrylate (2% pet.), textile dye mixt (6.6% pet.), linalool hydroperoxide (1% pet.), and limonene hydroperoxide (0.3% pet.) were, then, added to the series that agreed upon in 2016. Ethyldiamine and phenoxyethanol were excluded. Methyldibromoglutaronitrile, the mixture of sesquiterpene lactones, and hydroxyisohexyl 3-cyclohexene (Lyral) were also added to the extended Spanish series of 2022. (c) 2024 AEDV. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY -NC -ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Genetic Cross-Interaction between APOE and PRNP in Sporadic Alzheimer's and Creutzfeldt-Jakob Diseases

Alzheimer's disease (AD) and Creutzfeldt-Jakob disease (CJD) represent two distinct clinical entities belonging to a wider group, generically named as conformational disorders that share common pathophysiologic mechanisms. It is well-established that the APOE ε4 allele and homozygosity at polymorphic codon 129 in the PRNP gene are the major genetic risk factors for AD and human prion diseases, respectively. However, the roles of PRNP in AD, and APOE in CJD are controversial. In this work, we investigated for the first time, APOE and PRNP genotypes simultaneously in 474 AD and 175 sporadic CJD (sCJD) patients compared to a common control population of 335 subjects. Differences in genotype distribution between patients and control subjects were studied by logistic regression analysis using age and gender as covariates. The effect size of risk association and synergy factors were calculated using the logistic odds ratio estimates. Our data confirmed that the presence of APOE ε4 allele is associated with a higher risk of developing AD, while homozygosity at PRNP gene constitutes a risk for sCJD. Opposite, we found no association for PRNP with AD, nor for APOE with sCJD. Interestingly, when AD and sCJD patients were stratified according to their respective main risk genes (APOE for AD, and PRNP for sCJD), we found statistically significant associations for the other gene in those strata at higher previous risk. Synergy factor analysis showed a synergistic age-dependent interaction between APOE and PRNP in both AD (SF = 3.59, p = 0.027), and sCJD (SF = 7.26, p = 0.005). We propose that this statistical epistasis can partially explain divergent data from different association studies. Moreover, these results suggest that the genetic interaction between APOE and PRNP may have a biological correlate that is indicative of shared neurodegenerative pathways involved in AD and sCJD

Unsuspected and extensive transmission of a drug-susceptible Mycobacterium tuberculosis strain

<p>Abstract</p> <p>Background</p> <p>A large and unsuspected tuberculosis outbreak involving 18.7% of the total of the tuberculosis cases studied, was detected in a population-based molecular epidemiological study performed in Zaragoza (Spain) from 2001 to 2004.</p> <p>Methods</p> <p>The <it>Mycobacterium tuberculosis </it>drug-susceptible strain, named <it>MTZ </it>strain, was genetically characterized by IS<it>6110</it>-RFLP, Spoligotyping and by MIRU-VNTR typing and the genetic patterns obtained were compared with those included in international databases. The characteristics of the affected patients, in an attempt to understand why the <it>MTZ </it>strain was so highly transmitted among the population were also analyzed.</p> <p>Results</p> <p>The genetic profile of the <it>MTZ </it>strain was rare and not widely distributed in our area or elsewhere. The patients affected did not show any notable risk factor for TB.</p> <p>Conclusion</p> <p>The <it>M. tuberculosis </it>strain <it>MTZ</it>, might have particular transmissibility or virulence properties, and we believe that greater focus should be placed on stopping its widespread dissemination.</p

Role of the Cellular Prion Protein in Oligodendrocyte Precursor Cell Proliferation and Differentiation in the Developing and Adult Mouse CNS

There are numerous studies describing the signaling mechanisms that mediate oligodendrocyte precursor cell (OPC) proliferation and differentiation, although the contribution of the cellular prion protein (PrPc) to this process remains unclear. PrPc is a glycosyl-phosphatidylinositol (GPI)-anchored glycoprotein involved in diverse cellular processes during the development and maturation of the mammalian central nervous system (CNS). Here we describe how PrPc influences oligodendrocyte proliferation in the developing and adult CNS. OPCs that lack PrPc proliferate more vigorously at the expense of a delay in differentiation, which correlates with changes in the expression of oligodendrocyte lineage markers. In addition, numerous NG2-positive cells were observed in cortical regions of adult PrPc knockout mice, although no significant changes in myelination can be seen, probably due to the death of surplus cells

Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

11 páginas, 2 figuras, 1 tablaInappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resistance.I. Comas was supported by PID2019-104477RB-I00 from the Spanish Science Ministry and by ERC (CoG 101001038)Peer reviewe