Cost reduction in the processing department at Pugoda Textile Mill

Includes appendixesThis project has been undertaken to review and study the existing textile finishing process in the Processing Department of the pugoda Textile Mill, and to Propose cost reductive modifications a or new methods of practical importance. The suggestion made here are practicable under the existing set up of processing machinery ,While maintaining and ever . improving the present quality stranded conclude that there are large number of possibilities Of reducing cost by process modification and new method

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I

High-density lipoprotein (HDL) particles are cholesterol and lipid transport containers. Mature HDL particles destined for the liver develop through the formation of intermediate discoidal HDL particles, which are the primary acceptors for cholesterol. Here we present the three-dimensional structure of reconstituted discoidal HDL (rdHDL) particles, using a shortened construct of human apolipoprotein A-I, determined from a combination of nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR) and transmission electron microscopy (TEM) data. The rdHDL particles feature a protein double belt surrounding a lipid bilayer patch in an antiparallel fashion. The integrity of this structure is maintained by up to 28 salt bridges and a zipper-like pattern of cation-π interactions between helices 4 and 6. To accommodate a hydrophobic interior, a gross 'right-to-right' rotation of the helices after lipidation is necessary. The structure reflects the complexity required for a shuttling container to hold a fluid lipid or cholesterol interior at a protein:lipid ratio of 1:50

Genome duplication in a protein rich environment

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