Factores que afectan el impacto pesquero sobre peces cartilaginosos en el sureste español (Mediterráneo Suroccidental)

We propose a global index of impact based on the relative vulnerability of the local population of every species and the further application of regression trees globally optimized with evolutionary algorithms to study the fishing impact on the cartilaginous fish in southeastern Spain. The fishing impact is much higher in areas of less than 40 m depth within 11 km of the Cape Palos marine reserve. The impact also depends on the state of the sea and the kind of habitat. Deep-sea habitats associated with hard substrata and sandy beds show the highest impact, and sublittoral muds and habitats associated with circa littoral rocks with moderate energy show the lowest impact. The fishing impact changes throughout the moon cycle, showing different day-scale patterns associated with different habitats and different species compositions. Finally, we show that the global optimization of the regression trees can be essential to find some important patterns and that these trees are a useful tool for determining which areas are considered to be more important in terms of protection, taking into account specifically the vulnerability of the local populations.Proponemos un índice global de impacto basado en la vulnerabilidad relativa de las poblaciones locales de cada una de las especies y la posterior aplicación de árboles de regresión globalmente optimizados con algoritmos evolutivos, para estudiar el impacto de la pesca en los peces cartilaginosos del sureste español. El impacto de la pesca es mucho mayor, dentro de los 11 km de la reserva marina de Cabo de Palos, en aquellas zonas de menos de 40 m de profundidad. El impacto también depende del estado de la mar y el tipo de hábitat. Los hábitats de aguas profundas asociados a sustrato duro y fondo arenoso muestran los máximos impactos, mientras que, tanto los fondos fangosos sublitorales como los hábitats rocosos circalitorales con moderada energía de las corrientes, muestran un menor impacto. Además, se dan cambios a lo largo del ciclo lunar en el impacto de la pesca, lo que significa que existen diferentes patrones diarios, asociados a distintos hábitats, con distinta composición específica. Finalmente, mostramos que la optimización global de los árboles de regresión es esencial para revelar patrones importantes y son una herramienta útil para determinar aquellas áreas mas importantes en términos de protección, teniendo en cuenta, concretamente, la vulnerabilidad de las poblaciones locales

Hearing regeneration and regenerative medicine: present and future approaches

More than 5% of the world population lives with a hearing impairment. The main factors responsible for hearing degeneration are ototoxic drugs, aging, continued exposure to excessive noise and infections. The pool of adult stem cells in the inner ear drops dramatically after birth, and therefore an endogenous cellular source for regeneration is absent. Hearing loss can emerge after the degeneration of different cochlear components, so there are multiple targets to be reached, such as hair cells (HCs), spiral ganglion neurons (SGNs), supporting cells (SCs) and ribbon synapses. Important discoveries in the hearing regeneration field have been reported regarding stem cell transplantation, migration and survival; genetic systems for cell fate monitoring; and stem cell differentiation to HCs, SGNs and SCs using adult stem cells, embryonic stem cells and induced pluripotent stem cells. Moreover, some molecular mediators that affect the establishment of functional synapses have been identified. In this review, we will focus on reporting the state of the art in the regenerative medicine field for hearing recovery. Stem cell research has enabled remarkable advances in regeneration, particularly in neuronal cells and synapses. Despite the progress achieved, there are certain issues that need a deeper development to improve the results already obtained, or to develop new approaches aiming for the clinical application.Ministry of Economy and Competitiveness (Project CTQ2014-56611-R)Regional Government of Andalusia (Project P11-CTS-7651)Ramón Areces Foundation (Madrid, Spain

Blackspot seabream early life stages dispersal by hydrodynamic modelling (Strait of Gibraltar - Alboran Sea)

The Blackspot seabream (Pagellus bogaraveo) is a commercially appreciated demersal fish, widespread in the north-eastern Atlantic and middle-western Mediterranean. The Strait of Gibraltar (SoG) is an important fishing area where artisanal fleets from Spain and Morocco target this species using special longline gears known as “voracera”. Different studies on the health status of this species claim an overexploitation of the resource without any kind of objective management measures implemented yet by the associated countries. Improving the knowledge of the population dynamics, and particularly during the spawning window, is crucial for a better management of the fishing effort for this species. There is an agreement in literature in considering the SoG as an especially energetic and dispersive spawning zone for this species. Once spawned, eggs and larvae (ELS) are assumed to be scattered by the currents towards both sides of the SoG, mostly to the eastwards Alboran basin, where high concentrations of juveniles occur. A high resolution hydrodynamic model coupled to a Lagrangian particle tracking system is employed to assess the potential dispersal pathways of blackspot seabream ELS spawned in the SoG. Recursive releases of passive tracers in different virtual spawning spots and depths within the SoG region are tracked under different tidal conditions in order to obtain an overall characterization of the spatial dispersion patterns of the studied species. Semidiurnal tidal currents emerge as the primary factor in determining the horizontal dispersion and pathway of the spawning products, although the spring-neap tidal cycle and the spawning depth can be also important variables depending on the region considered as well as the arrival zone for the ELS dispersal paths over the Alboran SeaUniversidad de Málaga. Campus de Excelencia Internacional CEIMA

Live lecture screencast recording: a proposal to simplify the tasks associated with content production for video-teaching

Se trata de un resumen (Abstract) de la contribución. El acuerdo de transferencia de copyright del trabajo completo es incompatible con el depósito del mismo en RIUMA.Se describe la implementación inicial de un método simplificado de grabación en directo de sesiones de clase en asignaturas de las Escuelas de Ingeniería de la Universidad de Málaga. La simplificación se logra al incorporar en la actividad diaria del aula ciertas características típicas de la grabación en diferido de mini videos docentes. En una configuración mínima se graba únicamente el audio y el video en pantalla de la clase, evitando los desafíos técnicos y las dificultades que implica la grabación de otros elementos como la pizarra. Esto implica el uso de anotaciones en pantalla en tiempo real para reemplazar completamente las anotaciones en la pizarra.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. I Plan Propio Integral de Docencia. Universidad de Málaga. Universidad de Málaga. Vicerectorado de Personal Docente e Investigador, Proyectos de Innovación Educativa (PIE 17-018

Time-varying effective connectivity during visual object naming as a function of semantic demands

Accumulating evidence suggests that visual object understanding involves a rapid feedforward sweep, after which subsequent recurrent interactions are necessary. The extent to which recurrence plays a critical role in object processing remains to be determined. Recent studies have demonstrated that recurrent processing is modulated by increasing semantic demands. Differentially from previous studies, we used dynamic causal modeling to model neural activity recorded with magnetoencephalography while 14 healthy humans named two sets of visual objects that differed in the degree of semantic accessing demands, operationalized in terms of the values of basic psycholinguistic variables associated with the presented objects (age of acquisition, frequency, and familiarity). This approach allowed us to estimate the directionality of the causal interactions among brain regions and their associated connectivity strengths. Furthermore, to understand the dynamic nature of connectivity (i.e., the chronnectome; Calhoun et al., 2014) we explored the time-dependent changes of effective connectivity during a period (200–400 ms) where adding semantic-feature information improves modeling and classifying visual objects, at 50 ms increments. First, we observed a graded involvement of backward connections, that became active beyond 200 ms. Second, we found that semantic demands caused a suppressive effect in the backward connection from inferior frontal cortex (IFC) to occipitotemporal cortex over time. These results complement those from previous studies underscoring the role of IFC as a common source of top-down modulation, which drives recurrent interactions with more posterior regions during visual object recognition. Crucially, our study revealed the inhibitory modulation of this interaction in situations that place greater demands on the conceptual system

Green Marketing: Drivers in the Process of Buying Green Products—The Role of Green Satisfaction, Green Trust, Green WOM and Green Perceived Value

Green marketing is currently one of the most powerful strategies in the corporate world as it responds to a growing demand for green products. Therefore, this study aims to analyse the influence of green perceived value on green trust and green satisfaction, study how both variables impact green word of mouth in turn and, at the same time, how the three variables influence green purchase intention. Data collection was carried out through a digital survey of buyers of green products. The hypotheses posed were solved with a PLS-SEM model through the Smart-PLS software. The results showed that green perceived value positively affects green trust and green satisfaction. Furthermore, green satisfaction was found to influence green trust and green WOM. Green trust also influences green WOM. Regarding the antecedents of green purchase intention, only green satisfaction and green trust showed a positive relationship. In contrast, green WOM did not show a relationship with green purchase intention. The article shows the importance of green satisfaction for green companies in achieving green purchase intention, green WOM and green trust. Green perceived value is also an important variable, as it is the trigger for the process that leads to green purchase intention

How to Reach Green Word of Mouth through Green Trust, Green Perceived Value and Green Satisfaction

The production and consumption of green food products have become hot topics in marketing. Companies are implementing marketing strategies such as green perceived value, green trust, and green satisfaction to guarantee green word of mouth. An online questionnaire distributed through social media was used to collect the data. The sample consists of 297 people. The 297 responses were coded and analysed with the Software Smart-PLS. The data described include the sample sociodemographic profile, the descriptive analysis of all items, the reliability and validity of the measures of the reflective model and the evaluation of the results of the structural model. Four hypotheses included in the PLS-SEM proposed were validated for a p-value of 0.001. The results confirmed the influence of green perceived value on green trust and green satisfaction. Moreover, the results highlight that green satisfaction and green trust influence green word of mouth

Uso tutelado de la tomografía por emisión de positrones (PET) con 18FDG

El objetivo del UT de la 18FDG-PET es conocer la eficacia y efectividad de esta tecnología respecto a los procedimientos diagnósticos habituales

Comparison of three assays for total and free PSA using hybritech and WHO calibrations

Publisher Copyright: © 2021 International Institute of Anticancer Research. All rights reserved.Background/Aim: Lack of interchangeability between prostate-specific antigen (PSA) assays could have a clinical impact. We compared PSA assays from different manufacturers and calibrations. Patients and Methods: A total of 233 men who underwent prostate biopsy (PSA: 2-10 ng/ml; Beckman Coulter Access® Hybritech® as reference) were enrolled. Total (tPSA) and free PSA (fPSA) were also measured using the Roche cobas® and the Abbott Architect® methods. Results: Roche tPSA values were ≈ 1% higher than Beckman, while Abbott values were ~5% lower. Roche had the highest diagnostic sensitivity (92%) compared to Beckman Coulter (87%) and Abbott (85%). Roche fPSA was ≈3% lower and Abbott ≈17% higher than that of Beckman. For the percentage of fPSA, Roche had the highest sensitivity (98%). Conclusion: Roche cobas® and Beckman Coulter Access® Hybritech® tPSA were almost interchangeable. While the agreement was acceptable for tPSA, this did not happen with fPSA and greater efforts for harmonization are required.publishersversionpublishe

Hydrodinamic connectivity and dispersal patterns in the Strait of Gibraltar: implications for a transboundary species

The blackspot seabream is a highly appreciated species that has an important target of the Spanish and Moroccan fisheries in the transcontinental waters of the Strait of Gibraltar area (Gil, 2006). It is also one of the most exploited resources of the region, which has led to a notable drop of catches over the years, arriving to a vulnerable status nowadays. Consequently, a reduction of fishing mortality towards sustainability levels was recommended (GFCM, 2021). Improving our knowledge on the interaction of this species with its physical environment is a key issue in the efforts towards rebuilding the fishery target population until its maximum sustainable yield (Cowen et al., 2006). To gain insight into this interaction, a high-resolution circulation model coupled to a lagrangian tracking module has been employed, using eggs and larvae (early-life-stages, ELS) as purely passive particles advected by simulated currents. Several spawning scenarios consisting of different temporal (tidal phase and strength) and spatial (depths and sites) initial conditions have been analyzed to identify the most likely pathways of ELS dispersion. Eastward transport by the Atlantic Jet exiting the Strait of Gibraltar is the most influencing process in that dispersion. Regarding temporal fluctuations, fortnightly tidal modulation appears to be the prevailing factor determining the horizontal paths of ELS, being the spring tide responsible of the greatest scattering of eggs and larvae. Interestingly, the spatial distribution numerically simulated is consistent with results of larvae distribution obtained from samples collected during recent scientific surveys. The results presented in this study can be certainly different attending to the species strategy. The role of other important larval traits not included in this study requires also further research that may help decision-makers to establish biological rest periods that lead to maximize connectivity and sustainability