Initial teaching experience. A case study in the subject «New technologies applied to education»

En numerosas ocasiones no prestamos la atención que merece al proceso que una persona experimenta al iniciarse en el complejo mundo de la docencia. Cada etapa educativa tiene unas características bien definidas que condicionarán el trabajo y la adaptación del docente novel, en un proceso que no siempre es fácil. El presente artículo analiza la incorporación a la enseñanza de un profesor novel en la asignatura de Nuevas Tecnologías Aplicadas a la Educación (NNTT), en la Facultad de Educación y Trabajo Social de la Universidad de Valladolid (UVa). Para ello, hemos puesto en práctica un proceso de investigación interpretativo, siguiendo los principios del análisis cualitativo con estudio de casos (Stake, 1998) durante el curso académico 2007-2008. Las distintas peculiaridades teórico-prácticas del diseño de la asignatura se asientan en los principios establecidos dentro del campo del Computer Supported Collaborative Learning (CSCL) (Koschman, 1996) como mediador de procesos de enseñanza-aprendizaje, que a su vez, se apoyan en una metodología participativa basada en el Inquiry based Learning (IBL) (Bruce, 2000). Ante este diseño innovador, compartido a su vez por otros tres docentes en el seno de una comunidad de práctica educativa, hemos analizado el proceso de formación tecnológico-educativo llevado a cabo por este docente. A su vez, el análisis de esta experiencia nos ha ayudado a profundizar en la comprensión del tipo de competencias que los docentes noveles necesitan en diseños educativos como éste, en el proceso de convergencia propuesto por el Espacio Europeo de Educación Superior (EEES).Sometimes, we do not pay enough attention to the process experienced by a novice teacher when he plunges into the complex world of teaching. Each educational stage possesses some well-defined features which would influence the work and the adaptation of the novice teacher, everything immersed in a process which is not always easy. This paper analyzes the incorporation of a novice teacher into the teaching of an undergraduate course on Information and Communication Technologies to preservice teachers at the Faculty of Education and Social Work of the University of Valladolid. For that purpose, we have established an interpretative research process, following a Case Study approach (Stake, 1998) during the current academic year (2007-2008). The different theoretical and practical foundations of the curricular design of the course are based on the principles of the Computer Supported Collaborative Learning field (CSCL) (Koschman, 1996). As a well as in the ones promoted by Inquiry based Learning approach (IBL) (Bruce, 2000).Collaboration and technology are understood as mediators between teaching and learning processes. Through this innovative design— shared by a community of practice formed by other three teachers as well—, we have analysed both the technological and educative training process performed by this novice teacher. Moreover, the analysis of this experience has helped us to deepen in the understanding of the kind of competences which novice teachers require in curricular designs similar to this one within the European Convergence Process proposed by the European Space of Higher Education (ESHE)

Innovating in a 4th course of Chemical Engineering: A Bolognese Recipe

In this article we analyze a case study conducted within a pilot innovation experience in an undergraduate course on Chemical Engineering. The study was developed during three years, 2005/06, 2006/07 y 2007/08, at the University of Valladolid (Spain). The main goal of this work is to show evidence to better understand the methodological changes promoted by the aforementioned pilot experience, as well as to reflect on whether or not this sort of innovations help to reach EHEA thorny demands. The methodological innovation carried out in the course was based on active learning methods, such as Project-based Learning, and the study of real cases from multiple perspectives and subjects

Advantages and disadvantages of a interdisciplinary group in the face of European Space for Higher Education. Contributions to the processes of innovation and integration of ICT

La formación universitaria está viviendo uno de esos momentos donde el cambio se institucionaliza y hay que afrontar nuevos retos, básicamente impuestos. En ellos los docentes tendremos que asumir una modificación de nuestras percepciones y estar unidos para trabajar y converger en la universidad del Siglo XXI. Entendemos que es necesario el cambio, siempre y cuando lleve consigo un nuevo modelo de formación en el que el alumnado sea el protagonista de sus aprendizajes y el profesorado se convierta en facilitador de esos procesos. Para ello, deberá introducir nuevas formas de trabajo, tutoría, evaluación y seguimiento en las clases, bien empleando las Tecnologías de la Información y las Comunicaciones (TIC) como apoyo al proceso de enseñanza-aprendizaje, o incorporando nuevos materiales didácticos que favorezcan el aprendizaje autónomo del alumno y el desarrollo de competencias genéricas y específicas para su futuro profesional. En este artículo expondremos desde la perspectiva transversal de los participantes, las principales conclusiones extraídas del proyecto: Análisis y Estudio de Experiencias Colaborativas Apoyadas en E-Learning para el Espacio Europeo de Enseñanza Superior en la Universidad de Valladolid. (Curso 2007-2008). A lo largo del artículo analizaremos los puntos fuertes y débiles, los aciertos, los problemas y las soluciones comunes en relación con el uso de las TIC respecto a las distintas experiencias evaluadas. Todo ello, con la intención de promover sugerencias a un planteamiento común en su integración de cara a mejorar y facilitar el proceso formativo y adaptación a los criterios propuestos desde el EEES.In this moment, European Universities are experiencing one of those moments where change is institutionalized and they must face new challenges which are primarily imposing. Like teachers, we will have to assume a change in our perceptions working together to converge at the new universitary concept. For these reasons, we think change is necessary, but there is to build a new training model in which the students are the principle protagonists of their learning processes and teachers have to define the skills. At the same time, teachers must apply new methodologies, as well as mentoring and monitoring processes in their courses. In order to do this, they could use the Information and Communication Technologies (ICT) resources or other new sources which promote learning autonomous student and the development of generic and specific skills. In this article, we are going to present one of the project parts “Analysis and Study of collaborative experiences supported by E-Learning for the European Higher Education Area (EHEA) at the University of Valladolid”, which has taken place in 2007-2008. In this case, we have analysed some strength and weaknesses, as well as successes, problems and some possible solutions regarding the ICT use. One of our aims is to improve and facilitate these adaptation processes to the EHE

Effect of Intracrystalline Silanol Defects on the Diffusivity of Benzene in Silicalite Zeolite

[EN] Intracrystalline zeolite silanol defect groups (& EQUIV;SiOH) were modelled in silicalite (silica ZSM-5, MFI) using experimental data. We make a molecular dynamics study on the self-diffusivity of benzene in silicalite with defects. The simulations at three different loadings (1, 3 and 5 benzene per unit cell) and temperatures (298, 348 and 398 K) allow to calculate self-diffusivity, adsorption energy and the activation energy. The results show that benzene self-diffusivity in silicalite is increased by the presence of silanol defects. Previous experimental results support this claim.This work was supported by Generalitat Valenciana predoctoral fellowship GRISOLIAP/2019/084. We also thank Generalitat Valenciana for funding through PROMETEO/2021/077 project and CESGA for the use of computational facilities. Financial support by the Ministry of Science and Innovation (MICINN) of Spain through project CEX2021-001230-S (10.13039/501100011033) is gratefully acknowledged.Misturini, A.; Altundal, ÖF.; García-Aznar, P.; Kariminasab, S.; Sastre Navarro, GI. (2023). Effect of Intracrystalline Silanol Defects on the Diffusivity of Benzene in Silicalite Zeolite. Chemie Ingenieur Technik. 95(11):1768-1776. https://doi.org/10.1002/cite.20230000817681776951

Impact of the laser scanning strategy on the quality of 17-4PH stainless steel parts manufactured by selective laser melting

[EN] A significant correlation between scanning strategies and the quality of parts manufactured additively with Selective Laser Melting (SLM) technology is shown. Therefore, a in deep study of the influence of scanning strategy is of great value for the manufacturing process in order to promote SLM technology in applications with high service requirements. In particular, this research is carried out on 17-4PH stainless steel parts, which is an alloy widely used in sectors such as aerospace or automotive for its excellent mechanical properties. This research proposes to evaluate the properties of 17-4PH parts manufactured using three usual scanning strategies (normal, concentric and hexagonal) in order to optimize the SLM process depending on the final part application. According to the obtained results, the following general conclusions have been drawn. Hexagonal strategy can be considered the most appropriate in terms of porosity. Both hexagonal and normal strategy have good mechanical properties, as well as geometrical and dimensional quality. Regarding surface finish of top face (where the used scanning pattern is visible), normal strategy is the most appropriate. In general, concentric strategy presents different results from the others: larger and irregular pores, ductile tensile behaviour, low roughness on lateral faces, and high geometrical errors in samples with large scanning vectors. As a future work, it is proposed to manufacture SLM parts combining these strategies in order to improve their properties. In addition, it is proposed to evaluate the influence of different post-process operations on the quality of parts printed by SLM using different strategies.S

Advantages and disadvantages of a interdisciplinary group in the face of European Space for Higher Education. Contributions to the processes of innovation and integration of ICT

La formación universitaria está viviendo uno de esos momentos donde el cambio se institucionaliza y hay que afrontar nuevos retos, básicamente impuestos. En ellos los docentes tendremos que asumir una modificación de nuestras percepciones y estar unidos para trabajar y converger en la universidad del Siglo XXI. Entendemos que es necesario el cambio, siempre y cuando lleve consigo un nuevo modelo de formación en el que el alumnado sea el protagonista de sus aprendizajes y el profesorado se convierta en facilitador de esos procesos. Para ello, deberá introducir nuevas formas de trabajo, tutoría, evaluación y seguimiento en las clases, bien empleando las Tecnologías de la Información y las Comunicaciones (TIC) como apoyo al proceso de enseñanza-aprendizaje, o incorporando nuevos materiales didácticos que favorezcan el aprendizaje autónomo del alumno y el desarrollo de competencias genéricas y específicas para su futuro profesional. En este artículo expondremos desde la perspectiva transversal de los participantes, las principales conclusiones extraídas del proyecto: Análisis y Estudio de Experiencias Colaborativas Apoyadas en E-Learning para el Espacio Europeo de Enseñanza Superior en la Universidad de Valladolid. (Curso 2007-2008). A lo largo del artículo analizaremos los puntos fuertes y débiles, los aciertos, los problemas y las soluciones comunes en relación con el uso de las TIC respecto a las distintas experiencias evaluadas. Todo ello, con la intención de promover sugerencias a un planteamiento común en su integración de cara a mejorar y facilitar el proceso formativo y adaptación a los criterios propuestos desde el EEES.In this moment, European Universities are experiencing one of those moments where change is institutionalized and they must face new challenges which are primarily imposing. Like teachers, we will have to assume a change in our perceptions working together to converge at the new universitary concept. For these reasons, we think change is necessary, but there is to build a new training model in which the students are the principle protagonists of their learning processes and teachers have to define the skills. At the same time, teachers must apply new methodologies, as well as mentoring and monitoring processes in their courses. In order to do this, they could use the Information and Communication Technologies (ICT) resources or other new sources which promote learning autonomous student and the development of generic and specific skills. In this article, we are going to present one of the project parts “Analysis and Study of collaborative experiences supported by E-Learning for the European Higher Education Area (EHEA) at the University of Valladolid”, which has taken place in 2007-2008. In this case, we have analysed some strength and weaknesses, as well as successes, problems and some possible solutions regarding the ICT use. One of our aims is to improve and facilitate these adaptation processes to the EHE

1,7-Bay-Substituted Perylenediimide Derivative with Outstanding Laser Performance

Efficient ASE at wavelengths >620 nm from PS films doped with a bay-substituted perylenediimide (PDI) derivative is reported. The maximum PDI content is around 40 times larger than in prior studies. The ability to introduce large dye amounts into the film without photoluminescence (PL) quenching allows very high PL and ASE efficiencies with low thresholds. A distributed feedback (DFB) laser device using one of the best-performing films is fabricated and characterized.We thank support from the Spanish Government (MINECO), the European Community (FEDER) and the Generalitat Valenciana through MAT-2011–28167-C02, CTQ2011–26455, PROMETEO 2012/010 and ISIC/2012/008, as well as to the University of Alicante and the University Miguel Hernández de Elche

LAMP2 deficiency attenuates the neurodegeneration markers induced by HSV-1 infection

Mounting evidence suggests a major role of infectious agents in the pathogenesis of sporadic Alzheimer's disease (AD). Among them, herpes simplex virus type 1 (HSV-1) infection has emerged as a major factor in the etiology of AD. HSV-1 is able to induce some of the main alterations of the disease such as hyperphosphorylation of tau protein and accumulation of amyloid-β peptide. Functional genomic analysis of a cell model of HSV-1 infection and oxidative stress developed in our laboratory revealed lysosomal system to be the main pathway altered, and the lysosome-associated membrane protein 2 (LAMP2) gene one of the most strongly modulated genes. The aim of this work is to study LAMP2 as an AD candidate gene and to investigate its role in the neurodegeneration induced by HSV-1 using a LAMP2 knockdown cell model. LAMP2 deficiency led to a significant reduction of viral DNA replication and formation of infectious particles. In addition, tau hyperphosphorylation and inhibition of Aβ secretion induced by the virus were attenuated by the absence of LAMP2. Finally, genetic association studies revealed LAMP2 genetic variants to be associated with AD risk. In summary, our data indicate that LAMP2 could be a suitable candidate to mediate the AD-like phenotype caused by HSV-1.This work was supported by the Spanish Ministerio de Ciencia e Innovación (SAF 2017-85747-R); and the Ramon Areces Foundatio

Effect of Different Substitutions at the 1,7-Bay Positions of Perylenediimide Dyes on Their Optical and Laser Properties

Perylenediimide (PDI) compounds are widely used as the active units of thin-film organic lasers. Lately, PDIs bearing two sterically hindering diphenylphenoxy groups at the 1,7-bay positions have received attention because they provide a way to red-shift the emission with respect to bay-unsubstituted PDIs, while maintaining a good amplified spontaneous emission (ASE) performance at high doping rates. Here, we report the synthesis of a series of six PDI derivatives with different aryloxy groups (PDI 6 to PDI 10) or ethoxy groups (PDI 11) at the 1,7 positions of the PDI core, together with a complete characterization of their optical properties, including absorption, photoluminescence, and ASE. We aim to stablish structure-property relationships that help designing compounds with optimized ASE performance. Film experiments were accomplished at low PDI concentrations in the film, to resemble the isolated molecule behaviour, and at a range of increasing doping rates, to investigate concentration quenching effects. Compounds PDI 10 and PDI 7, bearing substituents in the 2′ positions of the benzene ring (the one contiguous to the linking oxygen atom) attached to the 1,7 positions of the PDI core, have shown a better threshold performance, which is attributed to conformational (steric) effects. Films containing PDI 11 show dual ASE.The research performed at the University of Alicante was funded by the “Ministerio de Ciencia e Innovación” (MCIN) of Spain and the European Regional Development Fund (grant No. PID2020-119124RB-I00) and from the Generalitat Valenciana through grant No. AICO/2021/093. This study is part of the Advanced Materials program supported by the Spanish MCIN with funding from European Union NextGenerationEU and by Generalitat Valenciana (grant no. MFA/2022/045). The research performed at Universidad Miguel Hernández de Elche was funded by the European Regional Development Fund “A way to make Europe” and the Spanish Ministerio de Ciencia e Innovación/Agencia Estatal de Investigación (project PID2019-109200GB-I00)

Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma Tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion.

Glioblastoma (GBM) is the most aggressive and frequent primary brain tumor in adults with a median overall survival of 15 months. Tumor recurrence and poor prognosis are related to cancer stem cells (CSCs), which drive resistance to therapies. A common characteristic in GBM is CDKN2A gene loss, located close to the cluster of type I IFN genes at Ch9p21. Newcastle disease virus (NDV) is an avian paramyxovirus with oncolytic and immunostimulatory properties that has been proposed for the treatment of GBM. We have analyzed the CDKN2A-IFN I gene cluster in 1018 glioma tumors and evaluated the NDV oncolytic e ect in six GBM CSCs ex vivo and in a mouse model. Our results indicate that more than 50% of GBM patients have some IFN deletion. Moreover, GBM susceptibility to NDV is dependent on the loss of the type I IFN. Infection of GBM with an NDV-expressing influenza virus NS1 protein can overcome the resistance to oncolysis by NDV of type I-competent cells. These results highlight the potential of using NDV vectors in antitumor therapies.post-print3309 K