First and second language interference on third language learning: Historical development of concepts from a psycholinguistic perspective

This research aims to provide a comprehensive historical overview of the concepts and theories that contribute to the explanation on how first and second language learning might interfere in third language learning from a psycholinguistic perspective. Besides the aforementioned, this paper offers a solid picture of the elements involved in the topic and their respective categorization to lead to substantial conclusions on the field to state clear differences among L1, L2 and L3 learning processes of late-sequential-additive bilingualism in adults, from a psycholinguistic perspective

Spatiotemporal Characteristics of the Largest HIV-1 CRF02_AG Outbreak in Spain: Evidence for Onward Transmissions

Background and Aim: The circulating recombinant form 02_AG (CRF02_AG) is the predominant clade among the human immunodeficiency virus type-1 (HIV-1) non-Bs with a prevalence of 5.97% (95% Confidence Interval-CI: 5.41–6.57%) across Spain. Our aim was to estimate the levels of regional clustering for CRF02_AG and the spatiotemporal characteristics of the largest CRF02_AG subepidemic in Spain.Methods: We studied 396 CRF02_AG sequences obtained from HIV-1 diagnosed patients during 2000–2014 from 10 autonomous communities of Spain. Phylogenetic analysis was performed on the 391 CRF02_AG sequences along with all globally sampled CRF02_AG sequences (N = 3,302) as references. Phylodynamic and phylogeographic analysis was performed to the largest CRF02_AG monophyletic cluster by a Bayesian method in BEAST v1.8.0 and by reconstructing ancestral states using the criterion of parsimony in Mesquite v3.4, respectively.Results: The HIV-1 CRF02_AG prevalence differed across Spanish autonomous communities we sampled from (p < 0.001). Phylogenetic analysis revealed that 52.7% of the CRF02_AG sequences formed 56 monophyletic clusters, with a range of 2–79 sequences. The CRF02_AG regional dispersal differed across Spain (p = 0.003), as suggested by monophyletic clustering. For the largest monophyletic cluster (subepidemic) (N = 79), 49.4% of the clustered sequences originated from Madrid, while most sequences (51.9%) had been obtained from men having sex with men (MSM). Molecular clock analysis suggested that the origin (tMRCA) of the CRF02_AG subepidemic was in 2002 (median estimate; 95% Highest Posterior Density-HPD interval: 1999–2004). Additionally, we found significant clustering within the CRF02_AG subepidemic according to the ethnic origin.Conclusion: CRF02_AG has been introduced as a result of multiple introductions in Spain, following regional dispersal in several cases. We showed that CRF02_AG transmissions were mostly due to regional dispersal in Spain. The hot-spot for the largest CRF02_AG regional subepidemic in Spain was in Madrid associated with MSM transmission risk group. The existence of subepidemics suggest that several spillovers occurred from Madrid to other areas. CRF02_AG sequences from Hispanics were clustered in a separate subclade suggesting no linkage between the local and Hispanic subepidemics

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Respuesta del cultivo de la menta (Mentha spicata L.) a la fertilización química y orgánica

With the purpose to define the appropriate doses in the production of mint cultivation, this research was conducted in three locations (Gibraltar, Arboleda and Aguacatal) of the municipality of Jardín, Antioquia. The soils of these localities are andisols, with medium contents of organic matter, low in interchangeable bases, low in phosphorus and boron, with characteristics of low fertility. For this research, Mentha spicata L. (mint) was seeded at a distance of 0.3x0.3 m, in an experimental design of randomized complete blocks with four repetitions, with five increasing doses of compound fertilizer (10-30-10) (0, 60, 120, 180, and 240 kg ha-1), in combination of five increasing doses of organic fertilizer (0, 1.8, 3.6, 5.4, and 7 t ha-1), and one control with a biological fertilizer. In five foliage harvests, the highest dry matter (DM) yields were achieved with the application of 180 and 120 kg ha-1 of 10-30-10, with yields of 156 and 158 g of DM per square meter, respectively.Con el propósito de definir las dosis apropiadas en la producción del cultivo de menta, se realizó la presente investigación en tres veredas (Gibraltar, Arboleda y Aguacatal) del municipio de Jardín, Antioquia. Los suelos de estas localidades son andisoles, con contenidos medios de materia orgánica, bajos en bases intercambiables, bajos en fósforo y boro, con características de baja fertilidad. Para esta investigación se sembró Mentha spicata L. (menta) a una distancia de 0,3x0,3 m, en un diseño experimental de bloques completos al azar con cuatro repeticiones, con cinco dosis crecientes de fertilizante compuesto (10-30-10) (0, 60, 120, 180 y 240 kg ha-1), en combinación con cinco dosis crecientes de fertilizante orgánico (0, 1.8, 3.6, 5.4 y 7 t ha-1), y un testigo con fertilizante biológico. En cinco cosechas de follaje, los mayores rendimientos de materia seca (MS) se lograron con la aplicación de 180 y 120 kg ha-1 de 10-30-10, con producciones de 156 y 158 g de MS por metro cuadrado, respectivamente

Efecto de la compatibilidad portainjerto/copa en los componentes de rendimiento del aguacate cv. Hass en tres localidades en Colombia

This work aimed to evaluate the effects of stem morphological alterations resulting from grafting, defined as compatibility and incompatibility between the rootstock and scion, on fruit yield and quality of avocado cv. Hass in three producing areas in Colombia (Rionegro, El Peñol and Anserma) over two consecutive years. Avocado orchards were established by seedlings obtained by grafting Hass scions upon creole rootstock seedlings. Avocado grafted plants were propagated with tip grafting, with a scion bud of cv. Hass (standard procedure). A split-plot design with a blocking factor per locality was used. Main plot corresponded to the harvest season, and subplots to rootstock/scion degree of compatibility. Results showed that compatibility treatments did not significantly affect yield (kg/tree) and fruit number per tree. In 2020, main harvest presented the highest yield (48.05 kg/tree) and fruit number (321 fruits/tree), while in 2021, secondary harvest presented the lowest yield (7.31 kg/tree) and the fruit number (52 fruits/tree). Main harvests contributed with 71.4% for total average production of each year, while secondary harvests completed the fruit yield with 28.6%. Finally, rootstock/scion compatibility did not affect fruit number, fruit caliber distribution, and yield per tree, while yield was affected solely by harvest season.El presente estudio tuvo como objetivo evaluar el efecto de las alteraciones morfológicas del tallo, definidas como compatibles e incompatibles entre portainjerto e injerto, sobre la producción y calidad de fruto de aguacate cv. Hass en tres zonas productoras de Colombia (Rionegro y El Peñol en Antioquia y Anserma en Caldas). Los huertos de aguacate se establecieron a partir de plántulas injertadas sobre patrones criollo provenientes de semilla. Las plantas injertadas de aguacate se propagaron mediante injerto de punta, con una vareta del cv. Hass (procedimiento estándar). Se utilizó un diseño de parcelas divididas con factor de bloqueo por localidad. La parcela principal correspondió a la época de cosecha y las subparcelas a la compatibilidad patrón/copa. El tratamiento de compatibilidad no afectó significativamente el rendimiento (kg/árbol) ni el número de frutos por árbol. La cosecha principal 2020M presentó los mayores rendimientos (48,05 kg/árbol) y número de frutos (321 frutos/árbol). La cosecha traviesa 2021SM tuvo los rendimientos más bajos (7,31 kg/árbol) y el menor número de frutos (52 frutos/árbol). Las cosechas 2020M y 2021M aportaron el 71,4% de la producción media de cada año, y las cosechas 2020SM y 2021SM completaron la producción de frutos con el 28,6% de la producción media anual. La compatibilidad de los árboles no afectó el número de frutos, la distribución del tamaño de los frutos ni el rendimiento por árbol. El rendimiento se vio afectado por el tiempo de cosecha

Ciencia y persuasión social en la medicalización de la infancia en España, siglos XIX-XX Science and social persuasion in the medicalization of childhood in 19th- and 20th-century Spain

Este trabajo indaga la conversión en rutinaria de la visita del médico de niños en España. Estudia la sustitución de modelos de atención al embarazo, parto y crianza, tradicionalmente opacos para varones y objeto de cuidados mediante agentes populares, por otros accesibles a la medicina académica. A partir de la situación existente a nivel popular en el último tercio del siglo XIX, exploramos la repercusión de campañas de divulgación científica - entendidas como crítica sin cuartel a lo que se construyó como cultura popular - y la proliferación de dispositivos asistenciales gratuitos. La oferta de vigilancia sobre la alimentación de lactantes permitió familiarizar a las madres con la asistencia facultativa en la enfermedad, hasta que, en la segunda mitad del siglo XX, la Pediatría se centró preferentemente en las patologías y la Puericultura dejó de ser especialidad médica para convertirse en identidad profesional subalterna.<br>The article explores how childhood visits to doctors first became routine in Spain. The introduction of new models of prenatal care, childbirth, and childrearing required the extension of academic medicine into a terrain traditionally occupied by practitioners of popular medicine. Focusing on the status quo for most of the population in the final third of the nineteenth century, the study examines the repercussion of the era's scientific outreach campaigns (expressions of harsh criticism of what popular culture had constructed) and the spread of free health assistance. In particular, it highlights how attention to the nutritional needs of nursing mothers helped these women gain familiarity with the medical assistance available in the case of illness - so much so that by the second half of the twentieth century, the issues of health education and promotion had been relegated to a secondary plane within the medical profession

How do women living with HIV experience menopause? Menopausal symptoms, anxiety and depression according to reproductive age in a multicenter cohort

CatedresBackground: To estimate the prevalence and severity of menopausal symptoms and anxiety/depression and to assess the differences according to menopausal status among women living with HIV aged 45-60 years from the cohort of Spanish HIV/AIDS Research Network (CoRIS). Methods: Women were interviewed by phone between September 2017 and December 2018 to determine whether they had experienced menopausal symptoms and anxiety/depression. The Menopause Rating Scale was used to evaluate the prevalence and severity of symptoms related to menopause in three subscales: somatic, psychologic and urogenital; and the 4-item Patient Health Questionnaire was used for anxiety/depression. Logistic regression models were used to estimate odds ratios (ORs) of association between menopausal status, and other potential risk factors, the presence and severity of somatic, psychological and urogenital symptoms and of anxiety/depression. Results: Of 251 women included, 137 (54.6%) were post-, 70 (27.9%) peri- and 44 (17.5%) pre-menopausal, respectively. Median age of onset menopause was 48 years (IQR 45-50). The proportions of pre-, peri- and post-menopausal women who had experienced any menopausal symptoms were 45.5%, 60.0% and 66.4%, respectively. Both peri- and post-menopause were associated with a higher likelihood of having somatic symptoms (aOR 3.01; 95% CI 1.38-6.55 and 2.63; 1.44-4.81, respectively), while post-menopause increased the likelihood of having psychological (2.16; 1.13-4.14) and urogenital symptoms (2.54; 1.42-4.85). By other hand, post-menopausal women had a statistically significant five-fold increase in the likelihood of presenting severe urogenital symptoms than pre-menopausal women (4.90; 1.74-13.84). No significant differences by menopausal status were found for anxiety/depression. Joint/muscle problems, exhaustion and sleeping disorders were the most commonly reported symptoms among all women. Differences in the prevalences of vaginal dryness (p = 0.002), joint/muscle complaints (p = 0.032), and sweating/flush (p = 0.032) were found among the three groups. Conclusions: Women living with HIV experienced a wide variety of menopausal symptoms, some of them initiated before women had any menstrual irregularity. We found a higher likelihood of somatic symptoms in peri- and post-menopausal women, while a higher likelihood of psychological and urogenital symptoms was found in post-menopausal women. Most somatic symptoms were of low or moderate severity, probably due to the good clinical and immunological situation of these women