Efecto de la densidad de alojamiento y la zona del galpón sobre indicadores de bienestar en pollos parrilleros

The aim of this work was to evaluate the effect of decreasing stocking density and shed area on footpad dermatitis, hock burn, and ventral feathers cleanliness of broilers reared in winter. The work was carried out on a commercial farm in the northeast of the Santa Fe province, Argentina. 54,000 broilers were housed in sex-mixed batches, in two darkened sheds, divided into three zones: Panels, Intermediate and Extractors. Two stocking densities were evaluated: 14 and 12 chickens/m2, standard and reduced, respectively. At 41 days feet and hock lesions and cleanliness of ventral feathers was assessed in 120 chickens per area. Significant differences were registered for footpad lesions in Extractors (p = 0.0006), Intermediate (p = 0.0002) and Panels (p <0.0001) zones, with predominance of lesions 1 and 2 in Intermediate and Panels zones with standard density. Non-significant differences were observed for hock lesions in Extractors (p = 0.111) a response not seen in Intermediate (p = 0.024) and Panels (p <0.0001) zones, with more type 2 lesions in both zones under standard density. Feather cleanliness showed significant differences in Extractors (p = 0.014) Intermediate (p = 0.01) and Panels (p <0.0001), with a higher proportion of type 3 plumage dirt with standard density. Welfare indicators behaviour showed the favourable change achieved by reducing stocking density in broilers production.El objetivo de este trabajo fue evaluar el efecto de la disminución de la densidad de alojamiento y de la zona del galpón sobre lesiones en almohadilla plantar, tarso y suciedad de plumas ventrales de pollos de engorde criados en invierno. El trabajo se realizó en una granja comercial en el noreste de la provincia de Santa Fe, Argentina. Se alojaron 54.000 pollos de engorde en lotes mixtos, en dos galpones oscurecidos, divididos en tres zonas: Paneles, Intermedia y Extractores. Se evaluaron dos densidades de alojamiento: 14 y 12 pollos/m2, estándar y reducida, respectivamente. A los 41 días se valoró la presencia de lesiones y suciedad del plumaje ventral en 120 pollos por zona. Las lesiones de almohadilla plantar registraron diferencias significativas en Extractores (p= 0,0006), Intermedia (p= 0,0002) y Paneles (p< 0,0001), con mayoría de lesiones 1 y 2 en Intermedia y Paneles con densidad estándar. Las lesiones de tarso no fueron significativas en Extractores (p= 0,1107), sí en Intermedia (p= 0,0235) y Paneles (p< 0,0001), ambas, con más lesiones tipo 2 en la densidad estándar. En suciedad de plumas hubo diferencias significativas en Extractores (p= 0,014), Intermedia (p= 0,01) y Paneles (p< 0,0001), con mayor proporción de plumaje tipo 3 en la densidad estándar. Las variables evaluadas dan cuenta del cambio favorable en la situación de bienestar alcanzada mediante la reducción de la densidad de alojamiento en pollos de engorde

Heterogeneity assessment of functional T cell avidity.

The potency of cellular immune responses strongly depends on T cell avidity to antigen. Yet, functional avidity measurements are rarely performed in patients, mainly due to the technical challenges of characterizing heterogeneous T cells. The mean functional T cell avidity can be determined by the IFN-γ Elispot assay, with titrated amounts of peptide. Using this assay, we developed a method revealing the heterogeneity of functional avidity, represented by the steepness/hillslope of the peptide titration curve, documented by proof of principle experiments and mathematical modeling. Our data show that not only natural polyclonal CD8 T cell populations from cancer patients, but also monoclonal T cells differ strongly in their heterogeneity of functional avidity. Interestingly, clones and polyclonal cells displayed comparable ranges of heterogeneity. We conclude that besides the mean functional avidity, it is feasible and useful to determine its heterogeneity (hillslope) for characterizing T cell responses in basic research and patient investigation

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.

BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700

Women from the Middle East and North Africa in Europe: Understanding their marriage and family dynamics

The aim of this article is to assist the understanding of social workers in Europe of marriage and family dynamics among women from Middle East and North African countries who have moved to Europe. The focus of this article is on husband selection processes and family dynamics after marriage in Egypt, which is used as a case study reflecting culture and norms surrounding marriage in this region. This article reports on the findings of doctoral studies which examined marriage patterns and family dynamics in North Africa and in particular in Egypt where more in-depth data were available. The authors reflect issues surrounding values and process of marriage not only in terms of the implications for practice with social work clients or service users, but also in relation to the potential of women from this region who may join the social care workforce

Design and testing of a composite bird strike resistant leading edge

The paper describes several innovative designs for a bird strike resistant composite leading edge for a Horizontal Tail Plane of an aircraft. These designs were based on a novel application of composites with high energy-absorbing characteristics: the tensor-skin concept. This paper describes the development of this energy-absorbing concept and its application to an impact resistant aircraft structure. The design philosophy, the fabrication and test of the first prototypes are discussed. Three improved leading edge structures with different energy-absorbing tensor concepts were manufactured. Bird-strike tests on these leading edges with a 4 lb synthetic bird at impact velocities around 100 m/s were performed. FE models were developed to simulate the unfolding of the tensor ply. Before each test was carried out, pre-test bird impact simulations were used to determine the impact test parameters and to predict the dynamic behaviour and failure mode of the structure

Predicting of ultrafiltration performances by advanced data analysis

International audienc

Impact of pretreatment conditions and chemical ageing on ultrafiltration membrane performances. Diagnostic of a coagulation/adsorption/filtration process

International audience5-year-old membranes autopsy revealed the absence of PVP inside the polymer.•5-year-old membranes were found much more sensitive to fouling than virgin membrane.•Fouling is strongly related to the degradation of PVP due to chlorine oxidation