One dimensional chain of quantum molecule motors as a mathematical physics model for muscle fibre

A quantum chain model of many molecule motors is proposed as a mathematical physics theory on the microscopic modeling of classical force-velocity relation and tension transients of muscle fibre. We proposed quantum many-particle Hamiltonian to predict the force-velocity relation for the slow release of muscle fibre which has no empirical relation yet, it is much more complicate than hyperbolic relation. Using the same Hamiltonian, we predicted the mathematical force-velocity relation when the muscle is stimulated by alternative electric current. The discrepancy between input electric frequency and the muscle oscillation frequency has a physical understanding by Doppler effect in this quantum chain model. Further more, we apply quantum physics phenomena to explore the tension time course of cardiac muscle and insect flight muscle. Most of the experimental tension transients curves found their correspondence in the theoretical output of quantum two-level and three-level model. Mathematically modeling electric stimulus as photons exciting a quantum three-level particle reproduced most tension transient curves of water bug Lethocerus Maximus.Comment: 16 pages, 12 figures, Arguments are adde

Microscopic origin of the mobility enhancement at a spinel/perovskite oxide heterointerface revealed by photoemission spectroscopy

The spinel/perovskite heterointerface $\gamma$-Al$_2$O$_3$/SrTiO$_3$ hosts a two-dimensional electron system (2DES) with electron mobilities exceeding those in its all-perovskite counterpart LaAlO$_3$/SrTiO$_3$ by more than an order of magnitude despite the abundance of oxygen vacancies which act as electron donors as well as scattering sites. By means of resonant soft x-ray photoemission spectroscopy and \textit{ab initio} calculations we reveal the presence of a sharply localized type of oxygen vacancies at the very interface due to the local breaking of the perovskite symmetry. We explain the extraordinarily high mobilities by reduced scattering resulting from the preferential formation of interfacial oxygen vacancies and spatial separation of the resulting 2DES in deeper SrTiO$_3$ layers. Our findings comply with transport studies and pave the way towards defect engineering at interfaces of oxides with different crystal structures.Comment: Accepted as Rapid Communications in Physical Review

HST Observations and Photoionization Modeling of the LINER Galaxy NGC 1052

We present a study of available Hubble Space Telescope (HST) spectroscopic and imaging observations of the low ionization nuclear emission line region (LINER) galaxy NGC 1052. The WFPC2 imagery clearly differentiates extended nebular Halpha emission from that of the compact core. Faint Object Spectrograph (FOS) observations provide a full set of optical and UV data (1200-6800 Angstroms). These spectral data sample the innermost region (0."86 x 0."86 ~ 82pc x 82pc) and exclude the extended Halpha emission seen in the WFPC2 image. The derived emission line fluxes allow a detailed analysis of the physical conditions within the nucleus. The measured flux ratio for Halpha/Hbeta, F{Halpha}/F{Hbeta}=4.53, indicates substantial intrinsic reddening, E(B-V)=0.42, for the nuclear nebular emission. This is the first finding of a large extinction of the nuclear emission line fluxes in NGC 1052. If the central ionizing continuum is assumed to be attenuated by a comparable amount, then the emission line fluxes can be reproduced well by a simple photoionization model using a central power law continuum source with a spectral index of alpha = -1.2 as deduced from the observed flux distribution. A multi-density, dusty gas gives the best fit to the observed emission line spectrum. Our calculations show that the small contribution from a highly ionized gas observed in NGC 1052 can also be reproduced solely by photoionization modeling. The high gas covering factor determined from our model is consistent with the assumption that our line of sight to the central engine is obscured.Comment: 23 pages, 7 Postscript figures, 1 jpeg figure ; uses aaspp4.sty, 11pt to appear in The Astrophysical Journa

Fungi of the Iowa Loess Hills

From 1981 through 1983 biological surveys of the Loess Hills were sponsored by the Iowa State Preserves Advisory Board. Twenty-four sites in 7 counties were visited during the first week in June during these years. Collections were made of all macrofungi producing identifiable fruiting structures or represented by recognizable weathered fruiting structures developed the previous fall. Plane parasitic fungi and corticolous lichens were also recorded. Fungi of the Loess Hills of Iowa had been previously documented primarily by Gilman\u27s and Gilman and Archer\u27s reports of plant parasitic fungi. This report includes 3 species of Oomycetes, 18 species of Myxomycetes, 67 species of Ascomycetes, 75 species of Basidiomycetes, 27 species of Fungi Imperfecti (Deuteromycetes) and 15 species of corticolous lichens

Gate-tunable, normally-on to normally-off memristance transition inpatterned LaAlO3/SrTiO3 interfaces

The authors gratefully acknowledge the support from the state of Bavaria as well as from the Deutsche Forschungsgemeinschaft (FOR1162 and SFB1170).We report gate-tunable memristive switching in patterned LaAlO3/SrTiO3 interfaces at cryogenic temperatures. The application of voltages in the order of a few volts to the back gate of the device allows controlling and switching on and -off the inherent memory functionality (memristance). For large and small gate voltages a simple non-linear resistance characteristic is observed while a pinched hysteresis loop and memristive switching occurs in an intermediate voltage range. The memristance is further controlled by the density of oxygen vacancies, which is tuned by annealing the sample at 300 °C in nitrogen atmosphere. Depending on the annealing time the memristance at zero gate voltage can be switched on and off leading to normally-on and normally-off memristors. The presented device offers reversible and irreversible control of memristive characteristics by gate voltages and annealing, respectively, which may allow to compensate fabrication variabilities of memristors that complicate the realization of large memristor-based neural networks.PostprintPeer reviewe

Plan, formulate, discuss and correlate a NASTRAN finite element vibrations model of the Boeing Model 360 helicopter airframe

Boeing Helicopter, together with other United States helicopter manufacturers, participated in a finite element applications program to emplace in the United States a superior capability to utilize finite element analysis models in support of helicopter airframe design. The activities relating to planning and creating a finite element vibrations model of the Boeing Model 36-0 composite airframe are summarized, along with the subsequent analytical correlation with ground shake test data

The transition of people’s preferences for the intervention of the government in the economy of re-unified Germany

Covering the first fifteen years immediately after German re- unification, this paper analyzes the people’s support to the transition. The focus is on individuals’ preferences for the intervention of the government in the economy and on the opinion about competition per se. Eastern German data are compared with Western German data. Using suitable data that allow for interpersonal comparisons, the paper shows that Eastern Germans have always preferred an intervention of the public hand in the economy deeper than Western Germans; these different positions have hardly converged during the examined period of time. However there are no significant differences with respect to how Germans perceive competition per se: it is considered as a good by the people living in both parts of the country.info:eu-repo/semantics/publishedVersio

Molecular gas in NUclei of GAlaxies (NUGA) VII. NGC4569, a large scale bar funnelling gas into the nuclear region

This work is part of the NUGA survey of CO emission in nearby active galaxies. We present observations of NGC4569, a member of the Virgo Cluster. We analyse the molecular gas distribution and kinematics in the central region and we investigate a possible link to the strong starburst present at the nucleus. 70% of the 1.1x10^9 Msolar of molecular gas detected in the inner 20" is found to be concentrated within the inner 800 pc and is distributed along the large scale stellar bar seen in near-infrared observations. A hole in the CO distribution coincides with the nucleus where most of the Halpha emission and blue light are emitted. The kinematics are modelled in three different ways, ranging from the purely geometrical to the most physical. This approach allows us to constrain progressively the physical properties of the galaxy and eventually to emerge with a reasonable fit to an analytical model of orbits in a barred potential. Fitting an axisymmetric model shows that the non-circular motions must be comparable in amplitude to the circular motions (120 km/s). Fitting a model based on elliptical orbits allows us to identify with confidence the single inner Lindblad resonance (ILR) of the large scale bar. Finally, a model based on analytical solutions for the gas particle orbits in a weakly barred potential constrained by the ILR radius reproduces the observations well. The mass inflow rate is then estimated and discussed based on the best fit model solution. The gravitational torques implied by this model are able to efficiently funnel the gas inside the ILR down to 300 pc, although another mechanism must take over to fuel the nuclear starburst inside 100 pc.Comment: accepted for publication in A&

A Structurally Simple Vaccine Candidate Reduces Progression and Dissemination of Triple-Negative Breast Cancer

The Tn antigen is a well-known tumor-associated carbohydrate determinant, often incorporated in glycopeptides to develop cancer vaccines. Herein, four copies of a conformationally constrained mimetic of the antigen TnThr (GalNAc-Thr) were conjugated to the adjuvant CRM197, a protein licensed for human use. The resulting vaccine candidate, mime[4]CRM elicited a robust immune response in a triple-negative breast cancer mouse model, correlated with high frequency of CD4+ T cells and low frequency of M2-type macrophages, which reduces tumor progression and lung metastasis growth. Mime[4]CRM-mediated activation of human dendritic cells is reported, and the proliferation of mime[4]CRM-specific T cells, in cancer tissue and peripheral blood of patients with breast cancer, is demonstrated. The locked conformation of the TnThr mimetic and a proper presentation on the surface of CRM197 may explain the binding of the conjugate to the anti-Tn antibody Tn218 and its efficacy to fight cancer cells in mice

Laser treatment in diabetic retinopathy

Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries due to macular edema and proliferative diabetic retinopathy (PDR). For both complications laser treatment may offer proven therapy: the Diabetic Retinopathy Study demonstrated that panretinal scatter photocoagulation reduces the risk of severe visual loss by >= 50% in eyes with high-risk characteristics. Pan-retinal scatter coagulation may also be beneficial in other PDR and severe nonproliferative diabetic retinopathy (NPDR) under certain conditions. For clinically significant macular edema the Early Treatment of Diabetic Retinopathy Study could show that immediate focal laser photocoagulation reduces the risk of moderate visual loss by at least 50%. When and how to perform laser treatment is described in detail, offering a proven treatment for many problems associated with diabetic retinopathy based on a high evidence level. Copyright (c) 2007 S. Karger AG, Basel