Atalanta y Meleagros. Un nuevo mosaico romano-oriental

Presentació i estudi d'un mosaic roma de paviment inedit d'una col.lecció particular. L'analisi permet proposar la seva procedencia de les províncies orientals de I'lmperi i una cronologia entre els segles III i IV d.J.C. El mosaic, figurat, s'afegeix al curt cataleg dels que representen a Meleagros i Atalanta (identificats per una inscripció en grec) en la interpretació erotica que s'origina al segle Ve a.J.C. S'analitza la seva relació dins el context iconografic, a la musivaria i altres medis, de I'art.Study of a previously unknown example of Roman mosaic pavement from a private collection. The analysis allows us to suggest that it comes from the Eastern provinces of the Roman Empire and that it dates from the third or fourth centuries A.D. The mosaic represents the figures of Meleagros and Athalante (identified by an inscription in greek) as an erotic couple, in accordance with the interpretation that originates from Greece in the fifth century B.C. Thesubject, rare in mosaic, ¡S analysed in connection with other roman works of art

Les recerques i les publicacions de Josep Gudiol i Cunill en el context científic i cultural català

La recent publicació d’un text inèdit de Josep Gudiol i Cunill enceta el debat sobre la seva figura i les seves aportacions científiques –moltes inèdites– en el context cultural de la Catalunya del seu temps. Les relacions de Gudiol amb les institucions culturals, la publicació –o no– dels seus estudis i, en particular, el seu paper en les primeres sistematitzacions sobre l’arquitectura romànica catalana són les qüestions que ací es plantegen

Calidad en las empresas del sector manufactura en Lima Metropolitana, 2014

Debido a la carencia de investigaciones en el sector sobre el nivel de calidad que existe en las empresas manufactureras de Lima Metropolitana se ha elaborado esta tesis, el cual tiene como objetivo identificar el nivel de cumplimiento de la Administración de la Calidad Total (TQM) en las empresas del sector manufactura de Lima Metropolitana. Benzaquen (2013) diseño los nueve factores que cubren a toda la organización: (a) alta gerencia, (b) planeamiento de la calidad, (c) auditoría y evaluación de la calidad, (d) diseño del producto, (e) gestión de la calidad del proveedor, (f) control y mejoramiento de procesos, (g) educación y entrenamiento, (h) círculos de calidad e (i) enfoque hacia la satisfacción del cliente. En dicho estudio, el autor suministró las pautas para enfocar y analizar de manera detallada los nueve factores del TQM. En el presente trabajo de investigación se identifica, describe y analiza las diferencias significativas que existen en el nivel del cumplimiento de los factores del TQM entre las empresas del sector manufactura de Lima Metropolitana que cuentan con un Sistema de Gestión de la Calidad (SGC) con aquellos que no cuentan con un SGC. Los datos se obtuvieron mediante las encuestas sobre el nivel de cumplimiento de los nueve factores del TQM de 191 empresas manufactureras, en un instante de tiempo, de las cuales el 51% tiene implementado un SGC. La investigación muestra la existencia de diferencias significativas en el nivel de cumplimiento del TQM entre las empresas que cuentan con un SGC con las empresas que no cuentan con un SGC.Due to the lack of research in the sector about the level of quality that exists in the manufacturing companies of Metropolitan Lima we have developed this thesis, which has as goal identify the level of compliance with Total Quality Management (TQM) in the manufacturing companies of Metropolitan Lima sector. Benzaquen (2013) designed the nine factors that cover the entire organization: (a) senior management, (b) quality planning, (c) audit and quality assessment, (d) product design, (e) management quality supplier, (f) control and process improvement, (g) education and training, (h) and quality circles (i) focus on customer satisfaction. In this study, the author provided the guidelines to focus and analyze in detail the nine factors of TQM. In this present research identifies, describes and analyzes the significant differences in the level of compliance of the factors of TQM among companies in the manufacturing sector in Metropolitan Lima who have a quality management system (QMS) with those who do not have a QMS. The data were obtained by surveying the level of compliance of the nine factors of TQM of 191 manufacturing companies, in an instant of time, of which 51% has implemented a QMS. Research shows that there are significant differences in the level of enforcement TQM among companies with a QMS with companies that do not have a QMS.Tesi

Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

Histone H4 acetylation at Lysine 16 (H4K16ac) is a key epigenetic mark involved in gene regulation, DNA repair and chromatin remodeling, and though it is known to be essential for embryonic development, its role during adult life is still poorly understood. Here we show that this lysine is massively hyperacetylated in peripheral neutrophils. Genome-wide mapping of H4K16ac in terminally differentiated blood cells, along with functional experiments, supported a role for this histone post-translational modification in the regulation of cell differentiation and apoptosis in the hematopoietic system. Furthermore, in neutrophils, H4K16ac was enriched at specific DNA repeats. These DNA regions presented an accessible chromatin conformation and were associated with the cleavage sites that generate the 50 kb DNA fragments during the first stages of programmed cell death. Our results thus suggest that H4K16ac plays a dual role in myeloid cells as it not only regulates differentiation and apoptosis, but it also exhibits a non-canonical structural role in poising chromatin for cleavage at an early stage of neutrophil cell death