478 research outputs found
Auxin regulates SCFTIR1-dependent degradation of AUX/IAA proteins
The plant hormone auxin is central in many aspects of plant development. Previous studies have implicated the ubiquitin-ligase SCFTIR1 and the AUX/IAA proteins in auxin response. Dominant mutations in several AUX/IAA genes confer pleiotropic auxin-related phenotypes, whereas recessive mutations affecting the function of SCFTIR1 decrease auxin response. Here we show that SCFTIR1 is required for AUX/IAA degradation. We demonstrate that SCFTIR1 interacts with AXR2/IAA7 and AXR3/IAA17, and that domain II of these proteins is necessary and sufficient for this interaction. Further, auxin stimulates binding of SCFTIR1 to the AUX/IAA proteins, and their degradation. Because domain II is conserved in nearly all AUX/IAA proteins in Arabidopsis, we propose that auxin promotes the degradation of this large family of transcriptional regulators, leading to diverse downstream effects
The Facilitation of Learning Groups: A Study of a Dairy Discussion Group Facilitator
Farm Management,
Dynamical mean-field theory of spiking neuron ensembles: response to a single spike with independent noises
Dynamics of an ensemble of -unit FitzHugh-Nagumo (FN) neurons subject to
white noises has been studied by using a semi-analytical dynamical mean-field
(DMF) theory in which the original -dimensional {\it stochastic}
differential equations are replaced by 8-dimensional {\it deterministic}
differential equations expressed in terms of moments of local and global
variables. Our DMF theory, which assumes weak noises and the Gaussian
distribution of state variables, goes beyond weak couplings among constituent
neurons. By using the expression for the firing probability due to an applied
single spike, we have discussed effects of noises, synaptic couplings and the
size of the ensemble on the spike timing precision, which is shown to be
improved by increasing the size of the neuron ensemble, even when there are no
couplings among neurons. When the coupling is introduced, neurons in ensembles
respond to an input spike with a partial synchronization. DMF theory is
extended to a large cluster which can be divided into multiple sub-clusters
according to their functions. A model calculation has shown that when the noise
intensity is moderate, the spike propagation with a fairly precise timing is
possible among noisy sub-clusters with feed-forward couplings, as in the
synfire chain. Results calculated by our DMF theory are nicely compared to
those obtained by direct simulations. A comparison of DMF theory with the
conventional moment method is also discussed.Comment: 29 pages, 2 figures; augmented the text and added Appendice
Meson screening masses from lattice QCD with two light and the strange quark
We present results for screening masses of mesons built from light and
strange quarks in the temperature range of approximately between 140 MeV to 800
MeV. The lattice computations were performed with 2+1 dynamical light and
strange flavors of improved (p4) staggered fermions along a line of constant
physics defined by a pion mass of about 220 MeV and a kaon mass of 500 MeV. The
lattices had temporal extents Nt = 4, 6 and 8 and aspect ratios of Ns / Nt \geq
4. At least up to a temperature of 140 MeV the pseudo-scalar screening mass
remains almost equal to the corresponding zero temperature pseudo-scalar (pole)
mass. At temperatures around 3Tc (Tc being the transition temperature) the
continuum extrapolated pseudo-scalar screening mass approaches very close to
the free continuum result of 2 \pi T from below. On the other hand, at high
temperatures the vector screening mass turns out to be larger than the free
continuum value of 2 \pi T. The pseudo-scalar and the vector screening masses
do not become degenerate even for a temperature as high as 4Tc. Using these
mesonic spatial correlation functions we have also investigated the restoration
of chiral symmetry and the effective restoration of the axial symmetry. We have
found that the vector and the axial-vector screening correlators become
degenerate, indicating chiral symmetry restoration, at a temperature which is
consistent with the QCD transition temperature obtained in previous studies. On
the other hand, the pseudo-scalar and the scalar screening correlators become
degenerate only at temperatures larger than 1.3Tc, indicating that the
effective restoration of the axial symmetry takes place at a temperature larger
than the QCD transition temperature.Comment: Published versio
News from the Muon (g-2) Experiment at BNL
The magnetic moment anomaly a_mu = (g_mu - 2) / 2 of the positive muon has
been measured at the Brookhaven Alternating Gradient Synchrotron with an
uncertainty of 0.7 ppm. The new result, based on data taken in 2000, agrees
well with previous measurements. Standard Model evaluations currently differ
from the experimental result by 1.6 to 3.0 standard deviations.Comment: Talk presented at RADCOR - Loops and Legs 2002, Kloster Banz,
Germany, September 8-13 2002, to be published in Nuclear Physics B (Proc.
Suppl.); 5 pages, 3 figure
Primordialists and Constructionists: a typology of theories of religion
This article adopts categories from nationalism theory to classify theories of religion. Primordialist explanations are grounded in evolutionary psychology and emphasize the innate human demand for religion. Primordialists predict that religion does not decline in the modern era but will endure in perpetuity. Constructionist theories argue that religious demand is a human construct. Modernity initially energizes religion, but subsequently undermines it. Unpacking these ideal types is necessary in order to describe actual theorists of religion. Three distinctions within primordialism and constructionism are relevant. Namely those distinguishing: a) materialist from symbolist forms of constructionism; b) theories of origins from those pertaining to the reproduction of religion; and c) within reproduction, between theories of religious persistence and secularization. This typology helps to make sense of theories of religion by classifying them on the basis of their causal mechanisms, chronology and effects. In so doing, it opens up new sightlines for theory and research
Talented suppliers? Strategic change and innovation in the UK aerospace industry
The 1990s marked the start of extensive re-structuring in the aerospace industry throughout the world. While the ensuing consolidation among prime contractors has been widely researched, the changes affecting the aerospace supply chain have received less attention. This study focuses on the re-structuring taking place within the supply chain of the UK aerospace industry. The findings point to extensive re-structuring. Unlike most earlier studies the lean supply model was found to be a powerful influence, with suppliers moving away from subcontractor status and instead taking on the mantle of âtalentedâ suppliers. While some of the implications of lean supply, in terms of the dynamics of innovation, were not apparent, there were modest signs of increased process innovation on the part of some suppliers
Observation of a Narrow Resonance of Mass 2.46 GeV/c^2 Decaying to D_s^*+ pi^0 and Confirmation of the D_sJ^* (2317) State
Using 13.5 inverse fb of e+e- annihilation data collected with the CLEO II
detector we have observed a narrow resonance in the Ds*+pi0 final state, with a
mass near 2.46 GeV. The search for such a state was motivated by the recent
discovery by the BaBar Collaboration of a narrow state at 2.32 GeV, the
DsJ*(2317)+ that decays to Ds+pi0. Reconstructing the Ds+pi0 and Ds*+pi0 final
states in CLEO data, we observe peaks in both of the corresponding
reconstructed mass difference distributions, dM(Dspi0)=M(Dspi0)-M(Ds) and
dM(Ds*pi0)=M(Ds*pi0)-M(Ds*), both of them at values near 350 MeV. We interpret
these peaks as signatures of two distinct states, the DsJ*(2317)+ plus a new
state, designated as the DsJ(2463)+. Because of the similar dM values, each of
these states represents a source of background for the other if photons are
lost, ignored or added. A quantitative accounting of these reflections confirms
that both states exist. We have measured the mean mass differences
= 350.0 +/- 1.2 [stat] +/- 1.0 [syst] MeV for the DsJ*(2317) state, and
= 351.2 +/- 1.7 [stat] +/- 1.0 [syst] MeV for the new DsJ(2463)+
state. We have also searched, but find no evidence, for decays of the two
states via the channels Ds*+gamma, Ds+gamma, and Ds+pi+pi-. The observations of
the two states at 2.32 and 2.46 GeV, in the Ds+pi0 and Ds*+pi0 decay channels
respectively, are consistent with their interpretations as (c anti-strange)
mesons with orbital angular momentum L=1, and spin-parities of 0+ and 1+.Comment: 16 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLNS, version to be published in Physical
Review D; minor modifications and fixes to typographical errors, plus an
added section on production properties. The main results are unchanged; they
supersede those reported in hep-ex/030501
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