Testbeam performance of a shashlik calorimeter with fine-grained longitudinal segmentation

An iron- plastic-scintillator shashlik calorimeter with a 4.3 X0 longitudinal segmentation was tested in November 2016 at the CERN East Area facility with charged particles up to 5 GeV . The performance of this detector in terms of electron energy resolution, linearity, response to muons and hadron showers are presented in this paper and compared with simulation. Such a fine-grained longitudinal segmentation is achieved using a very compact light readout system developed by the SCENTT and ENUBET Collaborations, which is based on fiber-SiPM coupling boards embedded in the bulk of the detector. We demonstrate that this system fulfills the requirements for neutrino physics applications and discuss performance and additional improvements

Utility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studies

Turmeric or Curcuma longa is a natural product, whose medicinal properties have been extensively studied and a wide variety of therapeutic effects on several diseases such as neurodegenerative, hepatic and renal damage, cancer, and diabetes have been mainly attributed to its curcuminoid content. In the last decades, diabetes mellitus has become an alarming worldwide health issue, because of the increasing number of people suffering from the disease, as well as the devastating consequences for them. In this paper, we review the current basic and clinical evidence about the potential of curcumin/curcuminoids for the treatment of diabetes mellitus, mainly by its hypoglycemic, antioxidant, and anti-inflammatory properties. The activity of curcumin (or curcuminoids) as a hypoglycemic agent or just as an adjuvant to improve the metabolic profile and to ameliorate the associated complications of diabetes mellitus, such as diabetic nephropathy and cardiopathy is discussed. The interactions between curcumin and conventional antidiabetic drugs might be explored for the therapeutic management of diabetes mellitus. Keywords: Diabetes mellitus, Curcumin, Glucose, Lipid