Irreducible Multiplets of Three-Quark Operators on the Lattice: Controlling Mixing under Renormalization

High luminosity accelerators have greatly increased the interest in semi-exclusive and exclusive reactions involving nucleons. The relevant theoretical information is contained in the nucleon wavefunction and can be parametrized by moments of the nucleon distribution amplitudes, which in turn are linked to matrix elements of three-quark operators. These can be calculated from first principles in lattice QCD. However, on the lattice the problems of operator mixing under renormalization are rather involved. In a systematic approach we investigate this issue in depth. Using the spinorial symmetry group of the hypercubic lattice we derive irreducibly transforming three-quark operators, which allow us to control the mixing pattern.Comment: 13 page

Eksperimentalna infektivna pneumokonioza

Quartz and coal-mine dusts were introduced into the lungs of rats by inhalation, in a high concentration, for four months, and then groups of these dusted animals were infected with a virulent strain of human tubercle bacillus (37 Rv). Dusting was continued for a further period of ten months in the case of coal-mine dust. No variation in lung pathology was seen in the quartz groups, although both produced classical silicotic nodules. In the coal-mine dust the infective group showed slightly more fibrosis, diffuse in nature, than either the noninfected or the tuberculous control group. These are preliminary experiments, and the results must be considered as both tentative and not very conclusive. Work is being continued.Prašina kvarca i ugljenokopna prašina bile su unesene inhalacijom u pluća štakora. Koncentracija je bila visoka, a ekspozicija je trajala 4 mjeseca Nakon toga su grupe zaprašenih životinja bile inficirane virulentnim sojom humanog tuberkuloznog bacila (H 37 Rv). Kod grupe životinja, koje su bile izvrgnute djelovanju ugljenokopne prašine, nastavljeno je zaprašivanje daljih 10 mjeseci. U kvarcnim grupama nije bilo razlike s obzirom na patologiju pluća, iako je u obje grupe došlo do stvaranja klasičnih silikotičnih čvorova. U grupi životinja, koje su bile izvrgnute ugljenokopnoj prašini, nađeno je nešto više fibroze, koja je bila difuzna, nego bilo u neinficiranoj ili tuberkuloznoj kontrolnoj grupi. Ti eksperimenti su preliminarni i ne treba ih smatrati previše konkluzivnima. Rad se nastavlja

Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice

AbstractGene targeting was used to delete exon 2 of mouse DOR-1, which encodes the δ opioid receptor. Essentially all 3H-[D-Pen2,D-Pen5]enkephalin (3H-DPDPE) and 3H-[D-Ala2,D-Glu4]deltorphin (3H-deltorphin-2) binding is absent from mutant mice, demonstrating that DOR-1 encodes both δ1 and δ2 receptor subtypes. Homozygous mutant mice display markedly reduced spinal δ analgesia, but peptide δ agonists retain supraspinal analgesic potency that is only partially antagonized by naltrindole. Retained DPDPE analgesia is also demonstrated upon formalin testing, while the nonpeptide δ agonist BW373U69 exhibits enhanced activity in DOR-1 mutant mice. Together, these findings suggest the existence of a second delta-like analgesic system. FinallyDOR-1 mutant mice do not develop analgesic tolerance to morphine, genetically demonstrating a central role for DOR-1 in this process

Baryon Distribution Amplitudes in QCD

We develop a new theoretical framework for the description of leading twist light-cone baryon distribution amplitudes which is based on integrability of the helicity $\lambda=3/2$ evolution equation to leading logarithmic accuracy. A physical interpretation is that one can identify a new `hidden' quantum number which distinguishes components in the $\lambda=3/2$ distribution amplitudes with different scale dependence. The solution of the corresponding evolution equation is reduced to a simple three-term recurrence relation. The exact analytic solution is found for the component with the lowest anomalous dimension for all moments $N$, and the WKB-type expansion is constructed for other levels, which becomes asymptotically exact at large $N$. Evolution equations for the $\lambda=1/2$ distribution amplitudes (e.g. for the nucleon) are studied as well. We find that the two lowest anomalous dimensions for the $\lambda=1/2$ operators (one for each parity) are separated from the rest of the spectrum by a finite `mass gap'. These special states can be interpreted as scalar diquarks.Comment: 75 pages, LaTeX style, 18 figures embedded with epsf.st

Advances in ab-initio theory of Multiferroics. Materials and mechanisms: modelling and understanding

Within the broad class of multiferroics (compounds showing a coexistence of magnetism and ferroelectricity), we focus on the subclass of "improper electronic ferroelectrics", i.e. correlated materials where electronic degrees of freedom (such as spin, charge or orbital) drive ferroelectricity. In particular, in spin-induced ferroelectrics, there is not only a {\em coexistence} of the two intriguing magnetic and dipolar orders; rather, there is such an intimate link that one drives the other, suggesting a giant magnetoelectric coupling. Via first-principles approaches based on density functional theory, we review the microscopic mechanisms at the basis of multiferroicity in several compounds, ranging from transition metal oxides to organic multiferroics (MFs) to organic-inorganic hybrids (i.e. metal-organic frameworks, MOFs)Comment: 22 pages, 9 figure

Coherent QCD phenomena in the Coherent Pion-Nucleon and Pion-Nucleus Production of Two Jets at High Relative Momenta

We use QCD to compute the cross section for coherent production of a di-jet (treated as a $q\bar q$ moving at high relative transverse momentum,$\kappa_t$). In the target rest frame,the space-time evolution of this reaction is dominated by the process in which the high $\kappa_t$ $q\bar q$ component of the pion wave function is formed before reaching the target. It then interacts through two gluon exchange. In the approximation of keeping the leading order in powers of $\alpha_s$ and all orders in $\alpha_{s}\ln(\kappa_{t}^2/k_{0}^2),$ the amplitudes for other processes are shown to be smaller at least by a power of $\alpha_{s}$. The resulting dominant amplitude is proportional to $z(1-z) \kappa_t^{-4}$ ($z$ is the fraction light-cone(+)momentum carried by the quark in the final state) times the skewed gluon distribution of the target. For the pion scattering by a nuclear target, this means that at fixed $x_{N}= 2\kappa_{t}^2/s$ (but $\kappa_{t}^2\to \infty$) the nuclear process in which there is only a single interaction is the most important one to contribute to the reaction. Thus in this limit color transparency phenomena should occur.These findings are in accord with E971 experiment at FNAL. We also re-examine a potentially important nuclear multiple scattering correction which is positive and $\propto A^{1/3}/\kappa_t^4$. The meaning of the signal obtained from the experimental measurement of pion diffraction into two jets is also critically examined and significant corrections are identified.We show also that for values of $\kappa_t$ achieved at fixed target energies, di-jet production by the e.m. field of the nucleus leads to an insignificant correction which gets more important as $\kappa_t$ increases.Comment: 23 pages, 9 figure

The Uses of Conformal Symmetry in QCD

The Lagrangian of Quantum Chromodynamics is invariant under conformal transformations. Although this symmetry is broken by quantum corrections, it has important consequences for strong interactions at short distances and provides one with powerful tools in practical calculations. In this review we give a short exposition of the relevant ideas, techniques and applications of conformal symmetry to various problems of interest.Comment: 110 pages, invited review for "Prog. Part. Nucl. Phys

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?

This work was supported by National Institute of Biomedical Imaging and Bioengineering Grant No. U54EB020403 (to the ENIGMA consortium)

Implementation of cervical cancer prevention services for HIV-infected women in Zambia: Measuring program effectiveness

Background: Cervical cancer kills more women in low-income nations than any other malignancy. A variety of research and demonstration efforts have proven the efficacy and effectiveness of low-cost cervical cancer prevention methods but none in routine program implementation settings of the developing world, particularly in HIV-infected women. Methods: In our public sector cervical cancer prevention program in Zambia, nurses conduct screening using visual inspection with acetic acid aided by digital cervicography. Women with visible lesions are offered same-visit cryotherapy or referred for histologic evaluation and clinical management. We analyzed clinical outcomes and modeled program effectiveness among HIV-infected women by estimating the total number of cervical cancer deaths prevented through screening and treatment. Results: Between 2006 and 2008, 6572 HIV-infected women were screened, 53.6% (3523) had visible lesions, 58.5% (2062) were eligible for cryotherapy and 41.5% (1461) were referred for histologic evaluation. A total of 75% (1095 out of 1462) of patients who were referred for evaluation complied. Pathology results from 65% (715 out of 1095) of women revealed benign abnormalities in 21% (151), cervical intraepithelial neoplasia (CIN) I in 30% (214), CIN 2/3 in 33% (235) and invasive cervical cancer in 16.1% (115, of which 69% were early stage). Using a conditional probability model, we estimated that our program prevented 142 cervical cancer deaths (high/low range: 238-96) among the 6572 HIV-infected women screened, or one cervical cancer death prevented per 46 (corresponding range: 28-68) HIV-infected women screened. Conclusion: Our prevention efforts using setting-appropriate human resources and technology have reduced morbidity and mortality from cervical cancer among HIV-infected women in Zambia. Financial support for implementing cervical cancer prevention programs integrated within HIV/AIDS care programs is warranted. Our prevention model can serve as the implementation platform for future low-cost HPV-based screening methods, and our results mayprovide the basis for comparison of programmatic effectiveness of future prevention efforts

Light Higgs boson discovery from fermion mixing

We evaluate the LHC discovery potential for a light Higgs boson in t tbar H (-> l nu b bbar b bbar jj) production, within the Standard Model and if a new Q=2/3 quark singlet T with a moderate mass exists. In the latter case, T pair production with decays T Tbar -> W+ b H tbar / H t W- bbar -> W+ b W- bbar H provides an important additional source of Higgs bosons giving the same experimental signature, and other decay modes T Tbar -> H t H tbar -> W+ b W- bbar H H, T Tbar -> Z t H tbar / H t Z tbar -> W+ b W- bbar H Z further enhance this signal. Both analyses are carried out with particle-level simulations of signals and backgrounds, including t tbar plus n=0...5 jets which constitute the main background by far. Our estimate for SM Higgs discovery in t tbar H production, 0.4 sigma significance for M_H = 115 GeV and an integrated luminosity of 30 fb^-1, is similar to the most recent ones by CMS which also include the full t tbar nj background. We show that, if a quark singlet with a mass m_T = 500 GeV exists, the luminosity required for Higgs discovery in this final state is reduced by more than two orders of magnitude, and 5 sigma significance can be achieved already with 8 fb^-1. This new Higgs signal will not be seen unless we look for it: with this aim, a new specific final state reconstruction method is presented. Finally, we consider the sensitivity to search for Q=2/3 singlets. The combination of these three decay modes allows to discover a 500 GeV quark with 7 fb^-1 of luminosity.Comment: LaTeX, 37 pages, 57 PS figures. Many improvements in the analysis. Final version to appear in JHE