666 research outputs found
A new regularization method for solving a time-fractional inverse diffusion problem
AbstractIn this paper, we consider an inverse problem for a time-fractional diffusion equation in a one-dimensional semi-infinite domain. The temperature and heat flux are sought from a measured temperature history at a fixed location inside the body. We show that such problem is severely ill-posed and further apply a new regularization method to solve it based on the solution given by the Fourier method. Convergence estimates are presented under the a priori bound assumptions for the exact solution. Finally, numerical examples are given to show that the proposed numerical method is effective
Identification of rice chromosome segment substitution line Z322-1-10 and mapping QTLs for agronomic traits from the F<sub>3</sub> population
Chromosome segment substitution lines (CSSLs) are powerful tools to combine naturally occurring genetic variants with favorable alleles in the same genetic backgrounds of elite cultivars. An elite CSSL Z322-1-10 was identified from advanced backcrosses between a japonica cultivar Nipponbare and an elite indica restorer Xihui 18 by SSR marker-assisted selection (MAS). The Z322-1-10 line carries five substitution segments distributed on chromosomes 1, 2, 5, 6 and 10 with an average length of 4.80 Mb. Spikilets per panicle, 1000-grain weight, grain length in the Z322-1-10 line are significantly higher than those in Nipponbare. Quantitative trait loci (QTLs) were identified and mapped for nine agronomic traits in an F3 population derived from the cross between Nipponbare and Z322-1-10 using the restricted maximum likelihood (REML) method in the HPMIXED procedure of SAS. We detected 13 QTLs whose effect ranging from 2.45% to 44.17% in terms of phenotypic variance explained. Of the 13 loci detected, three are major QTL (qGL1, qGW5-1 and qRLW5-1) and they explain 34.68%, 44.17% and 33.05% of the phenotypic variance. The qGL1 locus controls grain length with a typical Mendelian dominance inheritance of 3:1 ratio for long grain to short grain. The already cloned QTL qGW5-1 is linked with a minor QTL for grain width qGW5-2 (13.01%) in the same substitution segment. Similarly, the previously reported qRLW5-1 is also linked with a minor QTL qRLW5-2. Not only the study is important for fine mapping and cloning of the gene qGL1, but also has a great potential for molecular breeding
Expression of anion exchanger 2 in human gastric cancer
Anion exchanger 2 (AE2), which mediates exchange of Cl-/HCO3- across the plasma membrane, is widely expressed in body tissues. It is most abundantly expressed in stomach and is responsible for the uptake of Cl- ions that are destined to become HCl molecules. Aim: To determine whether AE2 expression was altered in gastric tumors. Methods: We have studied AE2 expression in normal human gastric tissues (n =16) and in gastric tumors (n = 33) using immunohistochemistry and immunofluorescent labeling. Results: In normal gastric tissue positive staining was observed in gastric fundus gland, suggesting parietal cell-related expression of AE2, and AE2 expression was localized in the nuclear membrane and even in cell nuclei. For assay of cancerous gastric tissues, specimens of human gastric cancer arising from the region of the fundus (2 cases), the body (14 cases) and the antrum (17 cases) were randomly selected. Immunohistochemical staining has showed that AE2 was down-regulated in all 14 cancerous gastric body specimens, whereas staining for AE2 in cancerous antrum was less intense and had a diffuse profile. Conclusions: The data suggest that AE2 might be associated with gastric carcinogenesis and the achlorhydria experienced by gastric cancer patients.Анионный обменник 2 (АЕ2), который опосредует перенос Cl-
/HCO3
-
через плазматическую мембрану, экспрессируется
клетками разных тканей. Самый высокий уровень экспрессии АЕ2 в желудке, поскольку этот белок отвечает за поглощение
ионов Cl-
, которые впоследствии используются для секреции HCl. Цель: Изучить изменения в экспрессии АЕ2 при раке
желудка. Методы: исследована экспрессия АЕ2 в нормальных тканях (n = 16) и опухолях желудка (n = 33) с применением
методов иммуногистохимии и иммунофлуоресценции. Результаты: в нетрансформированной ткани желудка в фундальной
железе выявляли сильную положительную реакцию, что свидетельствует об экспрессии АЕ2 париетальными клетками,
причем экспрессия АЕ2 была локализирована в ядерной мембране и в ядре. В опухолях желудка (фундального отдела (n =
2), тела (n = 14) и антрального отдела (n = 17)), отобранных случайным образом, был проведен анализ экспрессии АЕ2.
Иммуногистохимическое исследование показало снижение экспрессии АЕ2 во всех 14 случаях рака тела желудка. Окрашивание
АЕ2 в образцах рака антрального отдела желудка было менее интенсивным и диффузным. Выводы: полученные
данные позволяют предположить наличие связи между экспрессией АЕ2 и развитием рака желудка, а также ахлоргидрией,
отмечаемой у больных раком желудка
Large-space shell-model calculations for light nuclei
An effective two-body interaction is constructed from a new Reid-like
potential for a large no-core space consisting of six major shells and is used
to generate the shell-model properties for light nuclei from =2 to 6. (For
practical reasons, the model space is partially truncated for =6.) Binding
energies and other physical observables are calculated and compare favorably
with experiment.Comment: prepared using LaTex, 21 manuscript pages, no figure
Analysis of community structure of a microbial consortium capable of degrading benzo(a)pyrene by DGGE
A microbial consortium was obtained by enrichment culture of sea water samples collected from Botan oil port in Xiamen, China, using the persistent high concentration of a mixture of polycyclic aromatic hydrocarbons enrichment strategy. Denaturing gradient gel electrophoresis (DGGE) was used to investigate the bacterial composition and community dynamic changes based on PCR amplification of 16S rRNA genes during batch culture enrichment. Using the spray-plate method, three bacteria, designated as BL01, BL02 and BL03, which corresponded to the dominant bands in the DGGE profiles, were isolated from the consortium. Sequence analysis showed that BL01, BL02 and BL03 were phylogenetically close to Ochrobactrum sp., Stenotrophomonas maltophilia and Pseudomonas fluorescens, respectively. The degradation of benzo(a)pyrene (BaP), a model high-molecular-weight polycyclic aromatic hydrocarbon (HMW PAH) compound was investigated using individual isolates, a mixture of the three isolates, and the microbial consortium (BL) originally isolated from the oil port sea water. Results showed that the order of degradative ability was BL > the mixture of the three isolates > individual isolates. BL degraded 44.07% of the 10 ppm BaP after 14 days incubation, which showed the highest capability for HMW PAH compound degradation. Our results revealed that this high selective pressure strategy was feasible and effective in enriching the HMW PAH-degraders from the original sea water samples. (C) 2009 Elsevier Ltd. All rights reserved
Scaling of anisotropy flows in intermediate energy heavy ion collisions
Anisotropic flows (, and ) of light nuclear clusters are
studied by a nucleonic transport model in intermediate energy heavy ion
collisions. The number-of-nucleon scalings of the directed flow () and
elliptic flow () are demonstrated for light nuclear clusters. Moreover,
the ratios of of nuclear clusters show a constant value of 1/2
regardless of the transverse momentum. The above phenomena can be understood by
the coalescence mechanism in nucleonic level and are worthy to be explored in
experiments.Comment: Invited talk at "IX International Conference on Nucleus-Nucleus
Collisions", Rio de Janeiro, Aug 28- Sept 1, 2006; to appear on the
proceeding issue in Nuclear Physics
Azimuthal asymmetry of direct photons in intermediate energy heavy-ion collisions
Hard photon emitted from energetic heavy ion collisions is of very
interesting since it does not experience the late-stage nuclear interaction,
therefore it is useful to explore the early-stage information of matter phase.
In this work, we have presented a first calculation of azimuthal asymmetry,
characterized by directed transverse flow parameter and elliptic asymmetry
coefficient , for proton-neutron bremsstrahlung hard photons in
intermediate energy heavy-ion collisions. The positive and negative
of direct photons are illustrated and they seem to be anti-correlated to the
corresponding free proton's flow.Comment: 7 pages, 4 figures; accepted by Physics Letters
The effect of oxygen stoichiometry on electrical transport and magnetic properties of La0.9Te0.1MnOy
The effect of the variation of oxygen content on structural, magnetic and
transport properties in the electron-doped manganites La0.9Te0.1MnOy has been
investigated. All samples show a rhombohedral structure with the space group .
The Curie temperature decreases and the paramagnetic-ferromagnetic (PM-FM)
transition becomes broader with the reduction of oxygen content. The
resistivity of the annealed samples increases slightly with a small reduction
of oxygen content. Further reduction in the oxygen content, the resistivity
maximum increases by six orders of magnitude compared with that of the
as-prepared sample, and the r(T) curves of samples with y = 2.86 and y = 2.83
display the semiconducting behavior () in both high-temperature PM phase and
low-temperature FM phase, which is considered to be related to the appearance
of superexchange ferromagnetism (SFM) and the localization of carriers. The
results are discussed in terms of the combined effects of the increase in the
Mn2+/(Mn2++Mn3+) ratio, the partial destruction of double exchange (DE)
interaction, and the localization of carriers due to the introduction of oxygen
vacancies in the Mn-O-Mn network.Comment: 20 pages, 8 figure
Electronic Structures of Cu/S Co-doped/Anatase TiO 2 by First-principles
ABSTRACT The structural parameters, band structures and density of states of anatase TiO2 co-doped with Cu and S were calculated by first-principles based on the density functional theory. The results indicate that the volumes of the co-doped TiO2 increase due to the lattice distortion. The calculated X-ray diffraction pattern shows that the crystal phase of TiO2 is still kept as anatase after Cu and S co-doping. The band gap of TiO2 broadened when S substitutes for Ti or O along with Cu substitutes for Ti. The calculated partial density of states shows that the impurity energy levels mainly come from the Cu 3d and S 3p orbital. The calculated results may provide some theoretical foundations for the photocatalytic activity enhancement of TiO2 co-doped with Cu and S
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