Human Arm simulation for interactive constrained environment design

During the conceptual and prototype design stage of an industrial product, it is crucial to take assembly/disassembly and maintenance operations in advance. A well-designed system should enable relatively easy access of operating manipulators in the constrained environment and reduce musculoskeletal disorder risks for those manual handling operations. Trajectory planning comes up as an important issue for those assembly and maintenance operations under a constrained environment, since it determines the accessibility and the other ergonomics issues, such as muscle effort and its related fatigue. In this paper, a customer-oriented interactive approach is proposed to partially solve ergonomic related issues encountered during the design stage under a constrained system for the operator's convenience. Based on a single objective optimization method, trajectory planning for different operators could be generated automatically. Meanwhile, a motion capture based method assists the operator to guide the trajectory planning interactively when either a local minimum is encountered within the single objective optimization or the operator prefers guiding the virtual human manually. Besides that, a physical engine is integrated into this approach to provide physically realistic simulation in real time manner, so that collision free path and related dynamic information could be computed to determine further muscle fatigue and accessibility of a product designComment: International Journal on Interactive Design and Manufacturing (IJIDeM) (2012) 1-12. arXiv admin note: substantial text overlap with arXiv:1012.432

Inclusive Jet Production, Parton Distributions, and the Search for New Physics

Jet production at the Tevatron probes some of the smallest distance scales currently accessible. A gluon distribution that is enhanced at large x compared to previous determinations provides a better description of the Run 1b jet data from both CDF and D0. However, considerable uncertainty still remains regarding the gluon distribution at high x. In this paper, we examine the effects of this uncertainty, and of the remaining uncertainties in the NLO QCD theory, on jet cross section comparisons to Run 1b data. We also calculate the range of contributions still possible from any new physics. Predictions are also made for the expanded kinematic range expected for the ongoing Run 2 at the Tevatron and for the LHC.Comment: 50 pages, 31 figures, RevTe

Modeling transport through single-molecule junctions

Non-equilibrium Green's functions (NEGF) formalism combined with extended Huckel (EHT) and charging model are used to study electrical conduction through single-molecule junctions. Analyzed molecular complex is composed of asymmetric 1,4-Bis((2'-para-mercaptophenyl)-ethinyl)-2-acetyl-amino-5-nitro-benzene molecule symmetrically coupled to two gold electrodes [Reichert et al., Phys. Rev. Lett. Vol.88 (2002), pp. 176804]. Owing to this model, the accurate values of the current flowing through such junction can be obtained by utilizing basic fundamentals and coherently deriving model parameters. Furthermore, the influence of the charging effect on the transport characteristics is emphasized. In particular, charging-induced reduction of conductance gap, charging-induced rectification effect and charging-generated negative value of the second derivative of the current with respect to voltage are observed and examined for molecular complex.Comment: 8 pages, 3 figure

Muon anomalous magnetic moment in the standard model with two Higgs doublets

The muon anomalous magnetic moment is investigated in the standard model with two Higgs doublets (S2HDM) motivated from spontaneous CP violation. Thus all the effective Yukawa couplings become complex. As a consequence of the non-zero phase in the couplings, the one loop contribution from the neutral scalar bosons could be positive and negative relying on the CP phases. The interference between one and two loop diagrams can be constructive in a large parameter space of CP-phases. This will result in a significant contribution to muon anomalous magnetic moment even in the flavor conserving process with a heavy neutral scalar boson ($m_h \sim$ 200 GeV) once the effective muon Yukawa coupling is large ($|\xi_\mu|\sim 50$). In general, the one loop contributions from lepton flavor changing scalar interactions become more important. In particular, when all contributions are positive in a reasonable parameter space of CP phases, the recently reported 2.6 sigma experiment vs. theory deviation can be easily explained even for a heavy scalar boson with a relative small Yukawa coupling in the S2HDM.Comment: 8 pages, RevTex file, 5 figures, published version Phys. Rev. D 54 (2001) 11501

Epidemiologic Features and Environmental Risk Factors of Severe Fever with Thrombocytopenia Syndrome, Xinyang, China

Background:Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in rural areas of Central China in 2009, caused by a novel bunyavirus, SFT

Doing synthetic biology with photosynthetic microorganisms

The use of photosynthetic microbes as synthetic biology hosts for the sustainable production of commodity chemicals and even fuels has received increasing attention over the last decade. The number of studies published, tools implemented, and resources made available for microalgae have increased beyond expectations during the last few years. However, the tools available for genetic engineering in these organisms still lag those available for the more commonly used heterotrophic host organisms. In this mini-review, we provide an overview of the photosynthetic microbes most commonly used in synthetic biology studies, namely cyanobacteria, chlorophytes, eustigmatophytes and diatoms. We provide basic information on the techniques and tools available for each model group of organisms, we outline the state-of-the-art, and we list the synthetic biology tools that have been successfully used. We specifically focus on the latest CRISPR developments, as we believe that precision editing and advanced genetic engineering tools will be pivotal to the advancement of the field. Finally, we discuss the relative strengths and weaknesses of each group of organisms and examine the challenges that need to be overcome to achieve their synthetic biology potential.Peer reviewe