THE 23 JULY 1930 EARTHQUAKE (MS=6.7) IN THE SOUTHERN APENNINES (ITALY): GEOLOGICAL AND HYDROLOGICAL EFFECTS

The 23 July 1930 earthquake (MS=6.7) in the Southern Apennines (Italy) was a catastrophic event that produced many effects such as surface faulting, fractures, landslides, settlements, hydrological changes, variations in chemical/ physical activity related to the volcanic and/or thermal zones and also acoustic and optical phenomena. It is the first great earthquake of the twentieth century that was studied, thanks to the hydrological monitoring network of the Italian Hydrographic Survey (IHS) set up from 1925 to 1929. For this earthquake we analysed the initial IHS hydrometric and pluviometric data, looking for significant anomalies in springs, water wells and mountain streams. Hydrological data relative to rivers, springs and water wells indicate that some changes can be correlated with the earthquake: a post-seismic excess discharge in some streams, pre- and co-seismic decreases in stream flows and water levels in wells, pre- and post-seismic increases in discharges. The pre- and co-seismic stresses and the tectonic deformations were studied in order to find a possible model of interaction between stress state and hydrological variations. The anomalies found in this work can be considered “rebound anomalies”, which are the most common precursor reported by several authors and related to increases in porosity and permeability caused by the fracturing that precedes an earthquake. An estimation of the total excess discharge (0.035 km3) caused by the Ms=6.7 Irpinia earthquake is consistent with the excess discharge of about 0.01 km3 determined for the Mw=6.9 Loma Prieta earthquake. To define the normal hydrodynamic behaviour of the considered aquifers, an analysis of the correlation between rainfalls and water levels and flow rates has been carried out. The delay of significant peaks in the correlograms of figure 7 with respect to the start of the hydrological anomaly and/or its duration, can define the space-time limits of the changes correlated with earthquake

Hydrological anomalies connected to earthquakes in southern Apennines (Italy)

The study of hydrological variations in the watersheds of seismic areas can be useful in order to acquire a new knowledge of the mechanisms by which earthquakes can produce hydrological anomalies. Italy has the availability of many long historical series both of hydrological parameters and of seismological data, and is an ideal laboratory to verify the validity of theoretical models proposed by various authors. In this work we analyse the hydrological anomalies associated with some of the big earthquakes that occurred in the last century in the southern Apennines: 1930, 1980 and 1984. For these earthquakes we analysed hydrometric and pluviometric data looking for significant anomalies in springs, water wells and mountain streams. The influence of rainfalls on the normal flows of rivers, springs and wells has been ascertained. Also, the earthquake of 1805, for which a lot of hydrological perturbations have been reported, is considered in order to point out effects imputable to this earthquake that can be similar to the effects of the other big earthquakes. The considered seismic events exhibit different modes of energy release, different focal mechanisms and different propagation of effects on the invested areas. Furthermore, even if their epicentres were not localised in contiguous seismogenetic areas, it seems that the hydrological effects imputable to them took place in the same areas. Such phenomena have been compared with macroseismic fields and transformed in parameters, in order to derive empirical relationships between the dimensions of the event and the characteristics of the hydrological variations. The results of this work point to a close dependence among hydrological anomalies, regional structures and fault mechanisms, and indicate that many clear anomalies have been forerunners of earthquakes. In 1993, the Naples Bureau of the Hydrographic National Service started the continuous monitoring of hydrologic parameters by a network of automatic stations and transmission in real time; presently 7 acquifers are under control in which also pH, <i>T</i> , salinity, electrical conductivity, dissolved oxygen are measured. We envisage to increase the number of monitoring sites and controlled parameters

Geochemical monitoring integrated in a real time hydrological network

Hydrological data relative to springs and water wells collected by the Hydrografic National Service in Naples indicate that some anomalies can be correlated with the seismic activity in Southern Apennines. In this paper we report some hydrological anomalies for the November 23, 1980 earthquake and suggest that an improvement of the hydrometeorological network of the Hydrographic National Service can reveal geochemical and hydrological anomalies before the earthquakes

A feasibility study for the provision of electronic healthcare tools and services in areas of Greece, Cyprus and Italy

Background: Through this paper, we present the initial steps for the creation of an integrated platform for the provision of a series of eHealth tools and services to both citizens and travelers in isolated areas of thesoutheast Mediterranean, and on board ships travelling across it. The platform was created through an INTERREG IIIB ARCHIMED project called INTERMED. Methods: The support of primary healthcare, home care and the continuous education of physicians are the three major issues that the proposed platform is trying to facilitate. The proposed system is based on state-of-the-art telemedicine systems and is able to provide the following healthcare services: i) Telecollaboration and teleconsultation services between remotely located healthcare providers, ii) telemedicine services in emergencies, iii) home telecare services for "at risk" citizens such as the elderly and patients with chronic diseases, and iv) eLearning services for the continuous training through seminars of both healthcare personnel (physicians, nurses etc) and persons supporting "at risk" citizens. These systems support data transmission over simple phone lines, internet connections, integrated services digital network/digital subscriber lines, satellite links, mobile networks (GPRS/3G), and wireless local area networks. The data corresponds, among others, to voice, vital biosignals, still medical images, video, and data used by eLearning applications. The proposed platform comprises several systems, each supporting different services. These were integrated using a common data storage and exchange scheme in order to achieve system interoperability in terms of software, language and national characteristics. Results: The platform has been installed and evaluated in different rural and urban sites in Greece, Cyprus and Italy. The evaluation was mainly related to technical issues and user satisfaction. The selected sites are, among others, rural health centers, ambulances, homes of "at-risk" citizens, and a ferry. Conclusions: The results proved the functionality and utilization of the platform in various rural places in Greece, Cyprus and Italy. However, further actions are needed to enable the local healthcare systems and the different population groups to be familiarized with, and use in their everyday lives, mature technological solutions for the provision of healthcare services

Seismically induced ground effects of the 1805, 1930 and 1980 earthquakes in the Southern Apennines (Italy

Seismically induced environmental effects (in particular, surfacefaults, ground cracks, slope failures, liquefaction, soil compaction, hydrological changes, tsunamis) are assumed to provide fundamentalinformation on the earthquake size and its intensity field, crucial for a more efficient seismic hazard assessment. Accordingly, this study is aimed at substantiating this assumption by showing that the knowledge about ground effects acquired in recent earthquakes, when combined with that illustrated in historical documents, allows to buildan improved picture of historic seismic events, with respect to that usually provided by the solely damage-based macroseismic scales. In this perspective, the environmental effects are analysed and cataloguedof three of the most ruinous earthquakes in Southern Italy of the last two centuries: the July 26,1805, Molise event (XI MCS, M 6.8), the July 23, 1930, Irpinia event (X MCS, M 6.7), and the November 23, 1980 Campania-Basilicata event (X MSK, Ms 6.9). The distribution of the earthquake environmental effects, in particular their distance from the known or supposed causative fault, has been investigated to obtain a more detailed and comprehensive picture of the macroseismic field, a key parameter in seismic hazard assessment and seismic zonation. KEY WORDS: historical seismicity, intensity, ground effects, earthquak

Ground effects and hydrological changes in the Southern Apennines (Italy) in response to the 23 July 1930 earthquake (<i>M_S</i>=6.7)

The 23 July 1930 earthquake (MS=6.7) in the Southern Apennines (Italy) was a catastrophic event that produced many effects such as surface faulting, fractures, landslides, settlements, hydrological changes, variations in chemical/physical activity related to the volcanic and/or thermal zones and also acoustic and optical phenomena. It is the first great earthquake of the twentieth century that was studied, thanks to the hydrological monitoring network of the Italian Hydrographic Survey (IHS) set up from 1925 to 1929. For this earthquake we analysed the initial IHS hydrometric and pluviometric data, looking for significant anomalies in springs, water wells and mountain streams. Hydrological data relative to rivers, springs and water wells indicate that some changes can be correlated with the earthquake: a post-seismic excess discharge in some streams, pre- and co-seismic decreases in stream flows and water levels in wells, pre- and post-seismic increases in discharges. The pre- and co-seismic stresses and the tectonic deformations were studied in order to find a possible model of interaction between stress state and hydrological variations. The anomalies found in this work can be considered "rebound anomalies", which are the most common precursor reported by many authors and related to increases in porosity and permeability caused by the fracturing that precedes an earthquake. An estimation of the total excess discharge (0.035 km3) caused by the MS=6.7 Irpinia earthquake is consistent with the excess discharge of about 0.01 km3 determined for the Mw=6.9 Loma Prieta earthquake

Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases

<p>Abstract</p> <p>Objective</p> <p>Parosteal osteosarcoma is a well-differentiated variant of osteosarcoma that affects the surface of the bone. The imaging pattern is very typical. We report two cases mimicking an osteochondroma, radiologically and histologically and propose an explanation.</p> <p>Material</p> <p>The review of 86 parosteal osteosarcomas of bone revealed this atypical pattern only once. A consultation case was received in the same time, and added to ours. Patients were 28 years old and 56 years old females. Imaging studies included two radiographs, two CTscans, one MRI examination and one bone scan and the results were compared to histology.</p> <p>Results</p> <p>On imaging, both lesions presented as ossified lobulated masses attached with a broad base to the underlying cortex. No radiolucent cleft separated the masses and the host bone and cortex continuity between the mass and the femur was seen, with medullary communication. The marrow of the mass had a different density and intensity compared to normal marrow. So, there were features of an osteochondroma (cortex and medullary continuity) and of a parosteal osteosarcoma (ossified marrow). Pathological assessment on the final specimen confirmed the presence of low-grade parosteal osteosarcomas, after an erroneous diagnosis of osteochondroma on the initial biopsy.</p> <p>Conclusions</p> <p>Parosteal osteosarcoma can be rarely confused with osteochondroma. A radiologic-pathologic correlation is essential. Cortex continuity is the most misleading imaging feature that may occur in parosteal osteosarcomas. A knowledge of this misleading pattern will help diagnose the lesion from the beginning.</p

Prevalence of interstitial pneumonia suggestive of COVID-19 at 18F-FDG PET/CT in oncological asymptomatic patients in a high prevalence country during pandemic period: a national multi-centric retrospective study

Purpose: To assess the presence and pattern of incidental interstitial lung alterations suspicious of COVID-19 on fluorine-18-fluorodeoxyglucose positron emission tomography (PET)/computed tomography (CT) ([18F]FDG PET/CT) in asymptomatic oncological patients during the period of active COVID-19 in a country with high prevalence of the virus. Methods: This is a multi-center retrospective observational study involving 59 Italian centers. We retrospectively reviewed the prevalence of interstitial pneumonia detected during the COVID period (between March 16 and 27, 2020) and compared to a pre-COVID period (January\u2013February 2020) and a control time (in 2019). The diagnosis of interstitial pneumonia was done considering lung alterations of CT of PET. Results: Overall, [18F]FDG PET/CT was performed on 4008 patients in the COVID period, 19,267 in the pre-COVID period, and 5513 in the control period. The rate of interstitial pneumonia suspicious for COVID-19 was significantly higher during the COVID period (7.1%) compared with that found in the pre-COVID (5.35%) and control periods (5.15%) (p&nbsp;&lt; 0.001). Instead, no significant difference among pre-COVID and control periods was present. The prevalence of interstitial pneumonia detected at PET/CT was directly associated with geographic virus diffusion, with the higher rate in Northern Italy. Among 284 interstitial pneumonia detected during COVID period, 169 (59%) were FDG-avid (average SUVmax of 4.1). Conclusions: A significant increase of interstitial pneumonia incidentally detected with [18F]FDG PET/CT has been demonstrated during the COVID-19 pandemic. A majority of interstitial pneumonia were FDG-avid. Our results underlined the importance of paying attention to incidental CT findings of pneumonia detected at PET/CT, and these reports might help to recognize early COVID-19 cases guiding the subsequent management

Open-label add-on treatment trial of minocycline in fragile X syndrome

<p>Abstract</p> <p>Background</p> <p>Fragile X syndrome (FXS) is a disorder characterized by a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socio-emotional problems. It is hypothesized that the absence of the fragile X mental retardation protein (FMRP) leads to higher levels of matrix metallo-proteinase-9 activity (MMP-9) in the brain. Minocycline inhibits MMP-9 activity, and alleviates behavioural and synapse abnormalities in <it>fmr1 </it>knockout mice, an established model for FXS. This open-label add-on pilot trial was conducted to evaluate safety and efficacy of minocycline in treating behavioural abnormalities that occur in humans with FXS.</p> <p>Methods</p> <p>Twenty individuals with FXS, ages 13-32, were randomly assigned to receive 100 mg or 200 mg of minocycline daily. Behavioural evaluations were made prior to treatment (baseline) and again 8 weeks after daily minocycline treatment. The primary outcome measure was the Aberrant Behaviour Checklist-Community Edition (ABC-C) Irritability Subscale, and the secondary outcome measures were the other ABC-C subscales, clinical global improvement scale (CGI), and the visual analog scale for behaviour (VAS). Side effects were assessed using an adverse events checklist, a complete blood count (CBC), hepatic and renal function tests, and antinuclear antibody screen (ANA), done at baseline and at 8 weeks.</p> <p>Results</p> <p>The ABC-C Irritability Subscale scores showed significant improvement (p < 0.001), as did the VAS (p = 0.003) and the CGI (p < 0.001). The only significant treatment-related side effects were minor diarrhea (n = 3) and seroconversion to a positive ANA (n = 2).</p> <p>Conclusions</p> <p>Results from this study demonstrate that minocycline provides significant functional benefits to FXS patients and that it is well-tolerated. These findings are consistent with the <it>fmr1 </it>knockout mouse model results, suggesting that minocycline modifies underlying neural defects that account for behavioural abnormalities. A placebo-controlled trial of minocycline in FXS is warranted.</p> <p>Trial registration</p> <p>ClinicalTrials.gov Open-Label Trial NCT00858689.</p