1,808 research outputs found
Métricas para la medición de las competencias generales y especÃficas para el Grado en IngenierÃa Informática
El proceso de elaboración de las memorias de
grado se ha basado en un conjunto de
competencias generales y especÃficas que, en la
mayorÃa de los casos, entrañan un alto nivel de
abstracción y ambigüedad. Por otro lado, la
aparición de las competencias no ha ayudado a los
alumnos a entender mejor en qué medida alcanzan
los objetivos de las diferentes asignaturas, ni a
tomar mejores decisiones sobre los pasos a seguir
en su carrera profesional. En este artÃculo se
pretende mostrar los resultados obtenidos durante
la investigación realizada, que ha tenido como
objetivo desgranar las competencias generales y
especÃficas del Grado en IngenierÃa Informática,
de modo que se ofrezca un acercamiento mucho
más concreto y detallado con las asignaturas y,
consecuentemente, que pueda justificarse
adecuadamente la forma en que las asignaturas
permiten alcanzar parcial o completamente las
competencias para el grado. Este enfoque, y su
orientación a obtener métricas sobre las que
valorar el grado en que se han alcanzado los
objetivos, también permitirá que los alumnos
puedan tomar mejores decisiones a la hora de
seleccionar las diferentes asignaturas del grado y
conocer para qué competencias están mejor
cualificados.SUMMARY -- The process of writing honours theses is based on
a set of general and specific competences which,
in the majority of cases, entail a high level of
abstraction and ambiguity. What is more, the
apparition of these competences has not helped
students towards a better understanding of the
extent to which they attain the objectives of their
various subjects, or to make better decisions as
regards the steps to follow in their professional
careers. The intention of this paper is to show the
results obtained during research whose objective
was to separate the general and specific
competences involved in the Computer
Engineering Degree in order to provide a much
more concrete and detailed approach to the
subjects, which will consequently allow the way
in which the subjects permit the partial or total
attainment of the competences for the degree to be
justified. This approach, and its orientation
towards obtaining metrics with which to evaluate
the degree to which the objectives have been
attained, will also allow students to make better
decisions when selecting various degree subjects
and to discover for which competences they are
best qualified.Peer Reviewe
Induced Force Hovering of Spherical Robot by Under-Actuated Control of Dual Rotor
This chapter discusses the design and modelling of a spherical flying robot. The main objective is to control its hovering and omnidirectional mobility by controlling the air mass differential pressure between two asynchronous coaxial rotors that are aligned collinearly. The spherical robot design has embedded a gyroscopic mechanism of three rings that allow the rotors’ under-actuated mobility with 3DOF. The main objective of this study is to maintain the thrust force with nearly vertical direction. The change in pressure between rotors allows to vary the rotors’ tilt and pitch. The system uses special design propellers to improve the laminar air mass flux. A nonlinear fitting model automatically calibrates the rotors’ angular speed as a function of digital values. This model is the functional form that represents the reference input to control the rotors’ speed, validated by three types controllers: P, PI, and PID. The robot’s thrust and induced forces and flight mechanics are proposed and analysed. The simulation results show the feasibility of the approach
RhoA/ROCK regulation of neuritogenesis via profilin IIa–mediated control of actin stability
Neuritogenesis, the first step of neuronal differentiation, takes place as nascent neurites bud from the immediate postmitotic neuronal soma. Little is known about the mechanisms underlying the dramatic morphological changes that characterize this event. Here, we show that RhoA activity plays a decisive role during neuritogenesis of cultured hippocampal neurons by recruiting and activating its specific kinase ROCK, which, in turn, complexes with profilin IIa. We establish that this previously uncharacterized brain-specific actin-binding protein controls neurite sprouting by modifying actin stability, a function regulated by ROCK-mediated phosphorylation. Furthermore, we determine that this novel cascade is switched on or off by physiological stimuli. We propose that RhoA/ROCK/PIIa-mediated regulation of actin stability, shown to be essential for neuritogenesis, may constitute a central mechanism throughout neuronal differentiation
The African hind's (Cephalopholis taeniops, serranidae) use of artificial reefs off Sal Island (Cape Verde): a preliminary study based on acoustic telemetry
The African hind Cephalopholis taeniops (Valenciennes, 1828) is one of the most important commercial demersal species caught in the Cape Verde archipelago. The species is closely associated with hard substrate and is one of the main attractions for SCUBA divers. In January 2006 a former Soviet fishing vessel - the Kwarcit - was sunk off Santa Maria Bay (Sal Island). Young C. taeniops are commonly observed in this artificial reef (AR). In order to investigate the species' use of the AR, 4 specimens were captured and surgically implanted underwater with Vemco brand acoustic transmitters. The fish were monitored daily with an active telemetry receiver for one week after release. Simultaneously, an array of 3 passive VR2 / VR2W receivers was set for 63 days, registering data that allowed an analysis of spatial, daily and short term temporal activity patterns. The results showed site fidelity to the AR, with no migrations to the nearby natural reef. The method used allowed to register a consistent higher activity during daytime and a preference for the area opposite the dominant current
Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression
Author summary Outbreaks of the picornavirus foot-and-mouth disease virus (FMDV) have significant consequences for animal health and product safety and place a major economic burden on the global livestock industry. Understanding how this notorious animal pathogen suppresses the antiviral type I interferon (IFN-alpha/beta) response may help to develop countermeasures to control FMDV infections. FMDV suppresses the IFN-alpha/beta response through the activity of its Leader protein (L-pro), a protease that can cleave host cell proteins. L(pro)was also shown to have deubiquitinase and deISGylase activity, raising the possibility that L(pro)suppresses IFN-alpha/beta by removing ubiquitin and/or ISG15, two posttranslational modifications that can regulate the activation, interactions and localization of (signaling) proteins. Here, we show that TBK1 and MAVS, two signaling proteins that are important for activation of IFN-alpha/beta gene transcription, are cleaved by L-pro. By generating L(pro)mutants lacking either of these two activities, we demonstrate that L-pro's ability to cleave signaling proteins, but not its deubiquitination/deISGylase activity, correlates with suppression of IFN-beta gene transcription. The type I interferon response is an important innate antiviral pathway. Recognition of viral RNA by RIG-I-like receptors (RLRs) activates a signaling cascade that leads to type I interferon (IFN-alpha/beta) gene transcription. Multiple proteins in this signaling pathway (e.g. RIG-I, MDA5, MAVS, TBK1, IRF3) are regulated by (de)ubiquitination events. Most viruses have evolved mechanisms to counter this antiviral response. The leader protease (L-pro) of foot-and-mouth-disease virus (FMDV) has been recognized to reduce IFN-alpha/beta gene transcription; however, the exact mechanism is unknown. The proteolytic activity of L(pro)is vital for releasing itself from the viral polyprotein and for cleaving and degrading specific host cell proteins, such as eIF4G and NF-kappa B. In addition, L(pro)has been demonstrated to have deubiquitination/deISGylation activity. L-pro's deubiquitination/deISGylation activity and the cleavage/degradation of signaling proteins have both been postulated to be important for reduced IFN-alpha/beta gene transcription. Here, we demonstrate that TBK1, the kinase that phosphorylates and activates the transcription factor IRF3, is cleaved by L(pro)in FMDV-infected cells as well as in cells infected with a recombinant EMCV expressing L-pro.In vitrocleavage experiments revealed that L(pro)cleaves TBK1 at residues 692-694. We also observed cleavage of MAVS in HeLa cells infected with EMCV-L-pro, but only observed decreasing levels of MAVS in FMDV-infected porcine LFPK alpha V beta 6 cells. We set out to dissect L-pro's ability to cleave RLR signaling proteins from its deubiquitination/deISGylation activity, to determine their relative contributions to the reduction of IFN-alpha/beta gene transcription. The introduction of specific mutations, of which several were based on the recently published structure of L(pro)in complex with ISG15, allowed us to identify specific amino acid substitutions that separate the different proteolytic activities of L-pro. Characterization of the effects of these mutations revealed that L-pro's ability to cleave RLR signaling proteins but not its deubiquitination/deISGylation activity correlates with the reduced IFN-beta gene transcription
Métricas para la medición de las Competencias Generales y EspecÃficas para el Grado en IngenierÃa Informática
El proceso de elaboración de las memorias de grado se ha basado en un conjunto de competencias generales y especÃficas que, en la mayorÃa de los casos, entrañan un alto nivel de abstracción y ambigüedad. Por otro lado, la aparición de las competencias no ha ayudado a los alumnos a entender mejor en qué medida alcanzan los objetivos de las diferentes asignaturas, ni a tomar mejores decisiones sobre los pasos a seguir en su carrera profesional. En este artÃculo se pretende mostrar los resultados obtenidos durante la investigación realizada, que ha tenido como objetivo desgranar las competencias generales y especÃficas del Grado en IngenierÃa Informática, de modo que se ofrezca un acercamiento mucho más concreto y detallado con las asignaturas y, consecuentemente, que pueda justificarse adecuadamente la forma en que las asignaturas permiten alcanzar parcial o completamente las competencias para el grado. Este enfoque, y su orientación a obtener métricas sobre las que valorar el grado en que se han alcanzado los objetivos, también permitirá que los alumnos puedan tomar mejores decisiones a la hora de seleccionar las diferentes asignaturas del grado y conocer para qué competencias están mejor cualificados.The process of writing honours theses is based on a set of general and specific competences which, in the majority of cases, entail a high level of abstraction and ambiguity. What is more, the apparition of these competences has not helped students towards a better understanding of the extent to which they attain the objectives of their various subjects, or to make better decisions as regards the steps to follow in their professional careers. The intention of this paper is to show the results obtained during research whose objective was to separate the general and specific competences involved in the Computer Engineering Degree in order to provide a much more concrete and detailed approach to the subjects, which will consequently allow the way in which the subjects permit the partial or total attainment of the competences for the degree to be justified. This approach, and its orientation towards obtaining metrics with which to evaluate the degree to which the objectives have been attained, will also allow students to make better decisions when selecting various degree subjects and to discover for which competences they are best qualified
Nonadiabatic charged spherical gravitational collapse
We present a complete set of the equations and matching conditions required
for the description of physically meaningful charged, dissipative, spherically
symmetric gravitational collapse with shear. Dissipation is described with both
free-streaming and diffusion approximations. The effects of viscosity are also
taken into account. The roles of different terms in the dynamical equation are
analyzed in detail. The dynamical equation is coupled to a causal transport
equation in the context of Israel-Stewart theory. The decrease of the inertial
mass density of the fluid, by a factor which depends on its internal
thermodynamic state, is reobtained, with the viscosity terms included. In
accordance with the equivalence principle, the same decrease factor is obtained
for the gravitational force term. The effect of the electric charge on the
relation between the Weyl tensor and the inhomogeneity of energy density is
discussed.Comment: 23 pages, Latex. To appear in Phys. Rev. D. Some references correcte
Perfil do idoso em área metropolitana na região sudeste do Brasil: resultados de inquérito domiciliar
A multicentre study concerned with the health needs of the elderly population living in urban areas and coordinated by the Panamerican Health Organization was undertaken in 6 Latin-American countries. In Brazil, 1,602 elderly residents (of 60 years of age and over) in the District of S. Paulo, constituting a multistage random sample stratified by socioeconomic status, participated in a household survey using a multidemensional functional assessment questionnaire. The results showed a highly deprived population (70% had a per capita income of less than US$ 100 per month), living mostly in multigenerational households (59% were living with children and/or grandchildren), with a high prevalence of chronic physical illnesses (only 14% referred no illness) and psychiatric disorders (27% were considered psychiatric cases), a high proportion of them showing a loss of autonomy (47% needed help in performing at least one of the activities of daily living). The results are put into perspective concerning future needs in terms of specialized health services and social support for the growing population of elderly people in Brazil.Trata-se de estudo multicêntrico visando levantar as necessidades de saúde da população de idosos residentes em zona urbana, conduzido em 6 paÃses na América Latina e coordenado pela Organização Panamericana da Saúde. No Brasil, 1.602 idosos (60 anos e +) residentes no Distrito de São Paulo, participaram de inquérito domiciliar com questionário de avaliação funcional multidimensional - amostra populacional aleatória, em múltiplos estágios, estratificada por nÃvel socioeconômico. Os resultados mostraram uma população bastante carente (70% tinha uma renda per capita de menos de 100 dólares por mês), vivendo predominantemente em domicÃlios multigeracionais (59% viviam com os filhos e/ou com netos), com alta prevalência de doenças crônicas (somente 14% referiu não ter nenhuma doença) e distúrbios psiquiátricos (27% foram considerados casos psiquiátricos), e com uma elevada proporção de pessoas com perda de autonomia (47% precisavam de ajuda para realizar pelo menos uma das atividades da vida diária). Os resultados são analisados tendo em vista as demandas futuras por serviços de saúde especializados e suporte social por parte da crescente população de idosos no Brasil
MARISMA-BiDa: Gestión y Control del riesgo en Big Data. Caso de Estudio
En la actualidad, se genera una gran cantidad de
información debido a la amplia hiperconectividad y sensorización
del mundo que nos rodea. Esta información es considerada como
uno de los activos más importantes para las empresas en todos los
campos. El continuo crecimiento en la importancia y el volumen
de datos ha creado un nuevo problema: no puede ser manejado
por las técnicas de análisis tradicionales. Este problema se
resolvió, por lo tanto, mediante la creación de un nuevo
paradigma: Big Data. Sin embargo, Big Data originó nuevos
problemas relacionados no sólo con el volumen o la variedad de
los datos, sino también con la seguridad y privacidad de los datos.
Al adoptar nuevas soluciones tecnológicas como Big Data, todos
los riesgos deben ser identificados y gestionados. En este artÃculo
se presenta un caso de estudio de la aplicación de una técnica de
análisis y gestión de riesgos para entornos Big Data, guiada por
una metodologÃa de gestión de la seguridad (MARISMA) y
soportada por un entorno tecnológico en la nube (eMARISMA).
La propuesta, denominada MARISMA-BiDa es un patrón
especÃfico para Big Data que contiene los elementos necesarios
para facilitar la aplicación de la metodologÃa de análisis y gestión
de riesgos MARISMA en un entorno especÃfico y siguiendo los
principales estándares y recomendaciones internacionales
relacionados con Big Data (ISO/IEC, NIST, ENISA)
IRRIGATION DEFICIT STRATEGIES ON PHYSIOLOGICAL AND PRODUCTIVE PARAMETERS OF 'TOMMY ATKINS' MANGO
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