14 research outputs found
Precision of the current methods to measure the alkenone proxy UK'37 and absolute alkenone abundance in sediments : results of an interlaboratory comparison study
Measurements of the UK'37 index and the absolute abundance of alkenones in marine sediments are increasingly used in paleoceanographic research as proxies of past sea surface temperature and haptophyte (mainly coccolith-bearing species) primary productivity, respectively. An important aspect of these studies is to be able to compare reliably data obtained by different laboratories from a wide variety of locations. Hence the intercomparability of data produced by the research community is essential. Here we report results from an anonymous interlaboratory comparison study involving 24 of the leading laboratories that carry out alkenone measurements worldwide. The majority of laboratories produce data that are intercomparable within the considered confidence limits. For the measurement of alkenone concentrations, however, there are systematic biases between laboratories, which might be related to the techniques employed to quantify the components. The maximum difference between any two laboratories for any two single measurements of UK'37 in sediments is estimated, with a probability of 95%, to be <2.18C. In addition, the overall within-laboratory precision for the UK'37 temperature estimates is estimated to be <1.68C (95% probability). Similarly, from the analyses of alkenone concentrations the interlaboratory reproducibility is estimated at 32%, and the repeatability is estimated at 24%. The former is compared to a theoretical estimate of reproducibility and found to be excessively high. Hence there is certainly scope and a demonstrable need to improve reproducibility and repeatability of UK'37 and especially alkenone quantification data across the community of scientists involved in alkenone research
a necessary element in health care research !? Example: The Berlin Myocardial Infarction Registry
Guideline based treatment of 5079 patients (<=/>75years) with acute myocardial infarction of the Berlin Myocardial Infarction Registry
Domestic violence against women and health care demands. Results of a female emergency department patient survey
Umsetzung leitliniengerechter Therapie bei diabetischen Patienten mit akutem Herzinfarkt: Ergebnisse des Berliner Herzinfarktregisters (BHIR)
Unterschiede in der stationären Versorgung von Herzinfarktpatienten im europäischen Vergleich: Daten regionaler Herzinfarktregister aus Berlin, Dijon, Florenz, Tartu
Postgraduate qualifications in epidemiology in Germany. Experiences in Berlin, the current situation and future prospects
German initiative for specialized training programs in epidemiology
Wille L, Krämer A, Blettner M, et al. German initiative for specialized training programs in epidemiology. Das Gesundheitswesen. 2000;62(8-9):A89