Monopole condensation in the ground state of gauge theories: a disorder parameter

We construct a disorder parameter for dual superconductivity of the ground state of $U(1)$ gauge theory.Comment: 3 pages, contribution to the Lattice '94 conference, shell archive containing uuencoded LATEX file + 2 figure

Many-body effects in nuclear structure

We calculate, for the first time, the state-dependent pairing gap of a finite nucleus (120Sn) diagonalizing the bare nucleon-nucleon potential (Argonne v14) in a Hartree-Fock basis (with effective k-mass m_k eqult to 0.7 m), within the framework of the BCS approximation including scattering states up to 800 MeV above the Fermi energy to achieve convergence. The resulting gap accounts for about half of the experimental gap. We find that a consistent description of the low-energy nuclear spectrum requires, aside from the bare nucleon-nucleon interaction, not only the dressing of single-particle motion through the coupling to the nuclear surface, to give the right density of levels close to the Fermi energy (and thus an effective mass m* approximately equal to m), but also the renormalization of collective vibrational modes through vertex and self-energy processes, processes which are also found to play an essential role in the pairing channel, leading to a long range, state dependent component of the pairing interaction. The combined effect of the bare nucleon-nucleon potential and of the induced pairing interaction arising from the exchange of low-lying surface vibrations between nucleons moving in time reversal states close to the Fermi energy accounts for the experimental gap.Comment: 5 pages, 4 figures; author list correcte

Physiological relation between respiration activity and heterologous expression of selected benzoylformate decarboxylase variants in Escherichia coli

<p>Abstract</p> <p>Background</p> <p>The benzoylformate decarboxylase (BFD) from <it>Pseudomonas putida </it>is a biotechnologically interesting biocatalyst. It catalyses the formation of chiral 2-hydroxy ketones, which are important building blocks for stereoselective syntheses. To optimise the enzyme function often the amino acid composition is modified to improve the performance of the enzyme. So far it was assumed that a relatively small modification of the amino acid composition of a protein does not significantly influence the level of expression or media requirements. To determine, which effects these modifications might have on cultivation and product formation, six different BFD-variants with one or two altered amino acids and the wild type BFD were expressed in <it>Escherichia coli </it>SG13009 pKK233-2. The oxygen transfer rate (OTR) as parameter for growth and metabolic activity of the different <it>E. coli </it>clones was monitored on-line in LB, TB and modified PanG mineral medium with the Respiratory Activity MOnitoring System (RAMOS).</p> <p>Results</p> <p>Although the <it>E. coli </it>clones were genetically nearly identical, the kinetics of their metabolic activity surprisingly differed in the standard media applied. Three different types of OTR curves could be distinguished. Whereas the first type (clones expressing Leu476Pro-Ser181Thr or Leu476Pro) had typical OTR curves, the second type (clones expressing the wild type BFD, Ser181Thr or His281Ala) showed an early drop of OTR in LB and TB medium and a drastically reduced maximum OTR in modified PanG mineral medium. The third type (clone expressing Leu476Gln) behaved variable. Depending on the cultivation conditions, its OTR curve was similar to the first or the second type. It was shown, that the kinetics of the metabolic activity of the first type depended on the concentration of thiamine, which is a cofactor of BFD, in the medium. It was demonstrated that the cofactor binding strength of the different BFD-variants correlated with the differences in metabolic activity of their respective host strain.</p> <p>Conclusions</p> <p>The BFD-variants with high cofactor binding affinity (wild type, His281Ala, Ser181Thr) obviously extract thiamine from the medium and bind it tightly to the enzyme. This might explain the hampered growth of these clones. In contrast, growth of clones expressing variants with low cofactor binding affinity (Leu476His, Leu476Pro, Leu476Pro-Ser181Thr) is not impaired. Leu476Gln has an intermediate cofactor binding strength, thus, growth of its host strain depends on the specific cultivation conditions. This paper shows that slight differences of the amino acid composition can affect protein expression and cultivation and might require an adaptation of media components. Effects such as the observed are hardly foreseeable and difficult to detect in conventional screening processes. Via small scale experiments with on-line measurements in shake flasks such effects influencing the cultivation and product formation can be detected and avoided.</p

Flow equations for QED in the light front dynamics

The method of flow equations is applied to QED on the light front. Requiring that the partical number conserving terms in the Hamiltonian are considered to be diagonal and the other terms off-diagonal an effective Hamiltonian is obtained which reduces the positronium problem to a two-particle problem, since the particle number violating contributions are eliminated. No infrared divergencies appear. The ultraviolet renormalization can be performed simultaneously.Comment: 15 pages, Latex, 3 pictures, Submitted to Phys.Rev.

Oblique Confinement and Phase Transitions in Chern-Simons Gauge Theories

We investigate non-perturbative features of a planar Chern-Simons gauge theory modeling the long distance physics of quantum Hall systems, including a finite gap M for excitations. By formulating the model on a lattice, we identify the relevant topological configurations and their interactions. For M bigger than a critical value, the model exhibits an oblique confinement phase, which we identify with Lauglin's incompressible quantum fluid. For M smaller than the critical value, we obtain a phase transition to a Coulomb phase or a confinement phase, depending on the value of the electromagnetic coupling.Comment: 8 pages, harvmac, DFUPG 91/94 and MPI-PhT/94-9

Effective electron-electron and electron-phonon interactions in the Hubbard-Holstein model

We investigate the interplay between the electron-electron and the electron-phonon interaction in the Hubbard-Holstein model. We implement the flow-equation method to investigate within this model the effect of correlation on the electron-phonon effective coupling and, conversely, the effect of phonons in the effective electron-electron interaction. Using this technique we obtain analytical momentum-dependent expressions for the effective couplings and we study their behavior for different physical regimes. In agreement with other works on this subject, we find that the electron-electron attraction mediated by phonons in the presence of Hubbard repulsion is peaked at low transferred momenta. The role of the characteristic energies involved is also analyzed.Comment: 23 pages, 5 figure

Poincare Semigroup Symmetry as an Emergent Property of Unstable Systems

The notion that elementary systems correspond to irreducible representations of the Poincare group is the starting point for this paper, which then goes on to discuss how a semigroup for the time evolution of unstable states and resonances could emerge from the underlying Poincare symmetry. Important tools in this analysis are the Clebsch-Gordan coefficients for the Poincare group.Comment: 17 pages, 1 figur

Serum triiodothyronine levels and inflammatory cytokine production capacity

Increasing evidence suggests that pro-inflammatory cytokines are at play in lowering peripheral thyroid hormone levels during critical illness. Conversely, thyroid hormones have been suggested to enhance production of inflammatory cytokines. In view of these considerations, we hypothesized a mutual association between triiodothyronine and pro-inflammatory cytokines. Therefore we evaluated the relation between both circulating and induced inflammatory markers and serum thyroid function parameters in the Leiden 85-plus Study. We found that higher circulating levels of inflammatory markers were associated with lower levels of free serum triiodothyronine. In turn, higher serum free triiodothyronine levels were related to higher production capacity of pro-inflammatory cytokines after stimulation with lipopolysaccharide. By combining in vivo and ex vivo data, we were able to demonstrate for the first time the existence of a potential feedback mechanism between thyroid function and immune production capacity. We conclude that maintenance of normal thyroid function might be important for a preserved immune response in elderly human populations

The Critical Behaviour of Potts models with symmetry breaking fields

The $Q$-state Potts model in two dimensions in the presence of external magnetic fields is studied. For general $Q\geq3$ special choices of these magnetic fields produce effective models with smaller $Z(Q')$ symmetry $(Q'< Q)$. The phase diagram of these models and their critical behaviour are explored by conventional finite-size scaling and conformal invariance. The possibility of multicritical behavior, for finite values of the symmetry breaking fields, in the cases where $Q>4$ is also analysed. Our results indicate that for effective models with $Z(Q')$ symmetry $(Q'\leq4)$ the multicritical point occurs at zero field. This last result is also corroborated by Monte Carlo simulations.Comment: 15 pages (standart LaTex), 2 figure (PostScript) available by request to [email protected]