517 research outputs found
Mucoperiosteal Flaps with and without Removal of the Pocket Epithelium
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142171/1/jper0078.pd
Left Spigelian Hernia in Super-Obese Patient: A Case-Report.
Abstract: We report a case in which a giant Spigelian hernia presented with severe, persistent abdominal pain in a 62-
year-old super-obese woman with a history of total abdominal hysterectomy-bilateral salpingo-oopherectomy at the age of
40 years for benign neoplasia, who later underwent open hernia repair (maximal diameter of the hernia sac: 21 cm)
because of the development of compartment syndrome. Afterward, although a large incarcerated hernia disease was
found, the sac removal was technically difficult and an open procedure was carried out, with double-mesh placement. No
complications were recorded during the post-operative course.
We report a difficult issue related to the diagnosis and management of this pathology, underlining the complete surgical
repair to avoid hernia recurrence
Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes
Three platinum complexes with cis and trans configuration cis-[Pt(TCEP) 2 Cl 2 ], cis-[Pt(tmTCEP) 2 Cl 2 ] and trans-[Pt(TCEP) 2 Cl 2 ], where TCEP is tris(2-carboxyethyl)phosphine, have been synthesized and fully characterized by usual techniques including single-crystal X-ray diffraction for trans-[Pt(TCEP) 2 Cl 2 ] and cis-[Pt(tmTCEP) 2 Cl 2 ]. Here, we also report on an esterification process of TCEP, which takes place in the presence of alcohols, leading to a platinum complex coordinated to an ester tmTCEP (2-methoxycarbonylethyl phosphine) ligand. The stability in solution of the three compounds and their interaction with biological models such as DNA (pBR322 and calf thymus DNA) and proteins (lysozyme and RNase) have also been studied.This work was supported by Spanish MINECO: CTQ2015-68779R and CTQ2015-70371-RED
Linear and nonlinear optical absorption coefficients in GaAs/Ga1−xAlxAs concentric double quantum rings : Effects of hydrostatic pressure and aluminum concentration
ABSTRACT: The linear and nonlinear intra-band optical absorption coefficients in GaAs/Ga1−xAlxAs two-dimensional concentric double quantum rings are investigated. Taking into account the combined effects of hydrostatic pressure and aluminum concentration the energies of the ground and the first excited state have been found using the effective mass approximation and the transfer matrix formalism. The energies of these states and the corresponding threshold energy of the intra-band optical transitions are examined as a function of hydrostatic pressure and aluminum concentration for different sizes of the structure. We also investigated the dependencies of the linear, nonlinear, and total optical absorption coefficients as functions of the incident photon energy for different values of hydrostatic pressure, aluminum concentration, sizes of the structure, and incident optical intensity. Its is found that the effects of the hydrostatic pressure and the aluminum concentration lead to a shifting of the resonant peaks of the intra-band optical spectrum
Genetic structure of Antioquia Holstein from two SNPs and association with dairy traits
ABSTRACT Objective. Analyze the structure and genetic differentiation of a population of Antioquia Holstein cows from the polymorphisms A192G of INHA and A-320T of FSHR, and explore the association of the genotypic combinations with milk traits. Materials and methods. 1240 lactations of 356 animals from 9 herds in 6 municipalities of Antioquia were analyzed. Genotyping was performed by PCR-RFLP. Structure and genetic diversity parameters were determined using GenAlex software. The association of genotypes combinations with productive and reproductive traits was explored through a linear mixed model. Results. SNP A192G showed a frequency of 0.534 and 0.466 for A and G alleles respectively and SNP A-320T had a frequency of 0.660 far A allele and 0.339 for T allele, this way the population is in HWE. The FST, FIS and FIT values were 0.059, 0.285 and 0.328 respectively indicating a moderate genetic differentiation between subpopulations. The A-320T SNP showed significant effect on milk yield. Fat and protein percentage, calving interval and services per conception were not affected by these polymorphisms or their interaction. Conclusions. Phenotypic selection made on this population has not been strong enough to generate noticeable changes in allele frequencies of these polymorphisms or deviations from Hardy-Weinberg equilibrium. The interaction of these polymorphisms has no significant effect on the characteristics of zootechnical interest, so its use in programs of molecular marker assisted selection is not recommended
Aprendizagem organização: uma pesquisa empírica sobre o contexto de suporte à aprendizagem contínua
O presente artigo é uma contribuição à área de pesquisa empírica no âmbito de aprendizagem
organizacional, com base na revisão de literatura da área. Especificamente, analisa-se o
suporte do contexto organizacional voltado à aprendizagem contínua percebida pelos
funcionários de uma empresa privada de jornalismo em Brasília. O estudo tem como objetivo
analisar a percepção do suporte à aprendizagem contínua no trabalho desta empresa. Para
alcançar o objetivo, buscou-se seguir o caminho da conceituação e análise da aprendizagem
organizacional e não da empresa no qual o questionário foi aplicado. Primeiramente, fez-se
um levantamento teórico sobre os temas percepção, aprendizagem sobponto de vista
individual e organizacional e aprendizagem contínua e suporte à aprendizagem contínua. Na
pesquisa de campo quantitativa, fez-se a aplicação do questionário elaborado pela Drª Maria
Julia Pantoja (2004) em todos os funcionários da empresa. Assim sendo a diferenciação
demográfica foi feita apenas durante a análise dos resultados e considerações, não para
delimitar a amostra de pesquisa. Como principais resultados, foi observado que a confiança e
layout da empresa são percebidos como fatores que favorecem a aprendizagem
organizacional. Porém, o conhecimento da atividade e função dos colegas do grupo de
trabalho, assim como o incentivo a compartilhamento de experiência entre setores obtiveram
um baixo resultado. Juntamente com a teoria de base e análise qualitativa, o artigo agrega
valor empírico ao crescente tema de aprendizagem organizacional
Síntesis de pironas con posible actividad leishmanicida
Las passifloricinas son pironas naturales con una alta actividad leishmanicida; de ellas se han preparado varios análogos estructurales con el fin de mejorar su perfil farmacológico, En este trabajo se describe la secuencia sintética conducente a otros derivados. Estos posteriormente serán evaluadas contra amastigotes de Leishmania panamensis
Donor impurity-related linear and nonlinear intraband optical absorption coefficients in quantum ring : effects of applied electric field and hydrostatic pressure
ABSTRACT: The linear and nonlinear intraband optical absorption coefficients in GaAs three-dimensional single quantum rings are investigated. Taking into account the combined effects of hydrostatic pressure and electric field, applied along the growth direction of the heterostructure, the energies of the ground and first excited states of a donor impurity have been found using the effective mass approximation and a variational method. The energies of these states are examined as functions of the dimensions of the structure, electric field, and hydrostatic pressure. We have also investigated the dependencies of the linear, nonlinear, and total optical absorption coefficients as a function of incident photon energy for several configurations of the system. It is found that the variation of distinct sizes of the structure leads to either a redshift and/or a blueshift of the resonant peaks of the intraband optical spectrum. In Maddition, we have found that the application of an electric field leads to a redshift, whereas the influence of hydrostatic pressure leads to a blueshift (in the case of on-ring-center donor impurity position) of the resonant peaks of the intraband optical spectrum
Genetically-Engineered Pig-to-Baboon Liver Xenotransplantation: Histopathology of Xenografts and Native Organs
Abstract Orthotopic liver transplantation was carried out in baboons using wild-type (WT, n = 1) or genetically-engineered pigs (a1,3-galactosyltransferase gene-knockout, GTKO), n = 1; GTKO pigs transgenic for human CD46, n = 7) and a clinically-acceptable immunosuppressive regimen. Biopsies were obtained from the WT pig liver pre-Tx and at 30 min, 1, 2, 3, 4 and 5 h posttransplantation. Biopsies of genetically-engineered livers were obtained pre-Tx, 2 h after reperfusion and at necropsy (4-7 days after transplantation). Tissues were examined by light, confocal, and electron microscopy. All major native organs were also examined. The WT pig liver underwent hyperacute rejection. After genetically-engineered pig liver transplantation, hyperacute rejection did not occur. Survival was limited to 4-7 days due to repeated spontaneous bleeding in the liver and native organs (as a result of profound thrombocytopenia) which necessitated euthanasia. At 2 h, graft histology was largely normal. At necropsy, genetically-engineered pig livers showed hemorrhagic necrosis, platelet aggregation, platelet-fibrin thrombi, monocyte/macrophage margination mainly in liver sinusoids, and vascular endothelial cell hypertrophy, confirmed by confocal and electron microscopy. Immunohistochemistry showed minimal deposition of IgM, and almost absence of IgG, C3, C4d, C5b-9, and of a cellular infiltrate, suggesting that neither antibody-nor cell-mediated rejection played a major role
Utilizing active single-mode fiber injection for speckle nulling in exoplanet characterization
Despite recent advances in high-contrast imaging techniques, high resolution spectroscopy for characterization of exoplanet atmospheres is still limited by our ability to suppress residual starlight speckles at the planet’s location. We have demonstrated a new concept for speckle nulling by injecting directly imaged planet light into a single-mode fiber, linking a high-contrast adaptively-corrected coronagraph to a high-resolution spectrograph (diffraction-limited or not). The restrictions on the incident electric field that will couple into the single-mode fiber give the adaptive optics system additional degrees of freedom to suppress the speckle noise on top of destructive interference. We are able to achieve a starlight suppression gains that are an order of magnitude better than conventional techniques in broadband light with minimal planet throughput losses
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