Poemas de Calle Lomba : un poemario para inscribir la diferencia

El trabajo se ocupa de Poemas de calle Lomba, poemario en el que, de manera general, el poeta retoma los tópicos asociados a su identidad negra para insertarlos dentro de nuevos contextos locales y, al mismo tiempo, inscribirlos en problemáticas que se extienden más allá de estas fronteras regionales. Con un énfasis en los procesos socio-raciales los que rodean la creación de la obra estudiada, la investigación, por un lado, se acerca al lugar de enunciación del poeta cartagenero que, como veremos, pone de relieve las tensiones vinculadas a la discriminación racial y a la región del caribe como localidad periférica y, por otro lado, nos ayuda a interpretar e identificar las estrategias estéticas que inscriben la obra dentro de una poética de resistencia, legitimación y reivindicación de identidad negra y nación Caribe.The work deals Lomba street Poems, poems in which, generally, the poet takes the clichés associated with his black identity to insert into new local contexts and, at the same time, enroll them in issues that extend beyond of these regional boundaries. With an emphasis on socio-racial processes surrounding the creation of these works, research, on the one hand, approaches the poet's place of enunciation cartagenero that, as we shall see, highlights the tensions related to racial discrimination and Caribbean region as peripheral location and on the other hand, helps us interpret and identify the aesthetic strategies that register the work within a poetics of resistance, identity claim legitimacy and black Caribbean nation.Magíster en LiteraturaMaestrí

Ocupación e inclusión social. Boletín 4

Este Boletín difunde los resultados investigativos del grupo de investigación Ocupación e inclusión social de la Universidad Nacional de Colombia

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Poemas de Calle Lomba: un poemario para inscribir la diferencia.

El trabajo se ocupa de Poemas de calle Lomba, poemario en el que, de manera general, el poeta retoma los tópicos asociados a su identidad negra para insertarlos dentro de nuevos contextos locales y, al mismo tiempo, inscribirlos en problemáticas que se extienden más allá de estas fronteras regionales. Con un énfasis en los procesos socio-raciales los que rodean la creación de la obra estudiada, la investigación, por un lado, se acerca al lugar de enunciación del poeta cartagenero que, como veremos, pone de relieve las tensiones vinculadas a la discriminación racial y a la región del caribe como localidad periférica y, por otro lado, nos ayuda a interpretar e identificar las estrategias estéticas que inscriben la obra dentro de una poética de resistencia, legitimación y reivindicación de identidad negra y nación Caribe.The work deals Lomba street Poems, poems in which, generally, the poet takes the clichés associated with his black identity to insert into new local contexts and, at the same time, enroll them in issues that extend beyond of these regional boundaries. With an emphasis on socio-racial processes surrounding the creation of these works, research, on the one hand, approaches the poet's place of enunciation cartagenero that, as we shall see, highlights the tensions related to racial discrimination and Caribbean region as peripheral location and on the other hand, helps us interpret and identify the aesthetic strategies that register the work within a poetics of resistance, identity claim legitimacy and black Caribbean nation

Ocupación e inclusión social. Boletin

Este Boletín es el medio virtual de difusión de los avances del Grupo de investigación Ocupación e inclusión social, de la Universidad Nacional de Colombia

Ocupación e inclusión social. Boletín 2

Este boletín reporta los resultados de las investigaciones del grupo Ocupación e inclusión social, categorizado en D por Colciencias

FULL Investiga N°2

Contiene: Educación en competencias socio emocionales: una transformación escolar necesaria para las infancias / Lupe García Cano, Soledad Niño Murcia -- Economía Informal: la otra cara de la pandemia COVID-19 / Sandra Patricia Bohórquez Pacheco, Melva Inés Gómez Caicedo -- Valoración crítica de manuales de investigación contable: entre la orientación y la prescripción / Mateo Bedoya García, Andrés Cabrera Narváez, Fabián Leonardo Quinche Martín -- Formación docente en Colombia: una cuestión de calidad educativa / Juan Carlos Mariño Mendoza -- Didácticas y estrategias para el aprendizaje virtual del diseño / Nidia Raquel Gualdrón Cantor -- Panorama del sector turístico: tema de reflexión académica en el año 2020 / Ana Milena Luengas Alarcón -- Realidad Virtual bajo una visión modular de Industria 4.0 / Juan P. Navarro Londoño, Luis E. Vallejo Sánchez -- El poder de la voz para el control de las enfermedades crónicas / María Carolina Niño Rivera -- La ilustración gráfica aplicada al campo médico / Elena Patricia Ramírez Agudelo, Armando Armando -- Iglesia, prensa y anticlericalismo: escenarios del proyecto modernizador en la Colombia de mediados del siglo XIX / Roberto Herrera Cañón -- Reflexiones sobre la Ilustración gráfica en Colombia: la ilustración en la literatura infantil como otra manera de escribir / Juliet Daniela Galindo Zuleta, Edison Javier Mora González -- El ecosistema de emprendimiento en Bogotá, incipiente, pero en crecimiento / Yurian Adriana Bustamante Reyes, Danna Mitchelle Mejía Villarruel, Maicol Esneider Novoa González -- Intervención estatal: ¿contribuye o retarda el desarrollo económico? / María Fernanda León Castillo.Fundación Universitaria Los Libertadore

Discovering HIV related information by means of association rules and machine learning

Acquired immunodeficiency syndrome (AIDS) is still one of the main health problems worldwide. It is therefore essential to keep making progress in improving the prognosis and quality of life of affected patients. One way to advance along this pathway is to uncover connections between other disorders associated with HIV/AIDS-so that they can be anticipated and possibly mitigated. We propose to achieve this by using Association Rules (ARs). They allow us to represent the dependencies between a number of diseases and other specific diseases. However, classical techniques systematically generate every AR meeting some minimal conditions on data frequency, hence generating a vast amount of uninteresting ARs, which need to be filtered out. The lack of manually annotated ARs has favored unsupervised filtering, even though they produce limited results. In this paper, we propose a semi-supervised system, able to identify relevant ARs among HIV-related diseases with a minimal amount of annotated training data. Our system has been able to extract a good number of relationships between HIV-related diseases that have been previously detected in the literature but are scattered and are often little known. Furthermore, a number of plausible new relationships have shown up which deserve further investigation by qualified medical experts

COVID-19 in hospitalized HIV-positive and HIV-negative patients : A matched study

CatedresObjectives: We compared the characteristics and clinical outcomes of hospitalized individuals with COVID-19 with [people with HIV (PWH)] and without (non-PWH) HIV co-infection in Spain during the first wave of the pandemic. Methods: This was a retrospective matched cohort study. People with HIV were identified by reviewing clinical records and laboratory registries of 10 922 patients in active-follow-up within the Spanish HIV Research Network (CoRIS) up to 30 June 2020. Each hospitalized PWH was matched with five non-PWH of the same age and sex randomly selected from COVID-19@Spain, a multicentre cohort of 4035 patients hospitalized with confirmed COVID-19. The main outcome was all-cause in-hospital mortality. Results: Forty-five PWH with PCR-confirmed COVID-19 were identified in CoRIS, 21 of whom were hospitalized. A total of 105 age/sex-matched controls were selected from the COVID-19@Spain cohort. The median age in both groups was 53 (Q1-Q3, 46-56) years, and 90.5% were men. In PWH, 19.1% were injecting drug users, 95.2% were on antiretroviral therapy, 94.4% had HIV-RNA < 50 copies/mL, and the median (Q1-Q3) CD4 count was 595 (349-798) cells/μL. No statistically significant differences were found between PWH and non-PWH in number of comorbidities, presenting signs and symptoms, laboratory parameters, radiology findings and severity scores on admission. Corticosteroids were administered to 33.3% and 27.4% of PWH and non-PWH, respectively (P = 0.580). Deaths during admission were documented in two (9.5%) PWH and 12 (11.4%) non-PWH (P = 0.800). Conclusions: Our findings suggest that well-controlled HIV infection does not modify the clinical presentation or worsen clinical outcomes of COVID-19 hospitalization