141 research outputs found
Shock formation and the ideal shape of ramp compression waves
We derive expressions for shock formation based on the local curvature of the
flow characteristics during dynamic compression. Given a specific ramp adiabat,
calculated for instance from the equation of state for a substance, the ideal
nonlinear shape for an applied ramp loading history can be determined. We
discuss the region affected by lateral release, which can be presented in
compact form for the ideal loading history. Example calculations are given for
representative metals and plastic ablators. Continuum dynamics (hydrocode)
simulations were in good agreement with the algebraic forms. Example
applications are presented for several classes of laser-loading experiment,
identifying conditions where shocks are desired but not formed, and where long
duration ramps are desired
4U 1909+07: a well-hidden pearl
We present the first detailed spectral and timing analysis of the High Mass
X-ray Binary (HMXB) 4U 1909+07 with INTEGRAL and RXTE. 4U 1909+07 is detected
in the ISGRI 20-40 keV energy band with an average countrate of 2.6 cps. The
pulse period of ~604 sec is not stable, but changing erratically on timescales
of years. The pulse profile is strongly energy dependent: it shows a double
peaked structure at low energies, the secondary pulse decreases rapidly with
increasing energy and above 20 keV only the primary pulse is visible. This
evolution is consistent between PCA, HEXTE, and ISGRI. The phase averaged
spectrum can be well described by the sum of a photoabsorbed power law with a
cutoff at high energies and a blackbody component. To investigate the pulse
profile, we performed phase resolved spectral analysis. We find that the
changing spectrum can be best described with a variation of the folding energy.
We rule out a correlation between the black body component and the continuum
variation and discuss possible accretion geometries.Comment: 9 pages, 11 figures, accepted for publication in A&A Sect.
Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases
BACKGROUND: We prospectively reviewed response rates, local control, and side effects after non-fractionated stereotactic high single-dose body radiation therapy for lung tumors. METHODS: Fifty-eight patients underwent radiosurgery involving single-dose irradiation. With 25 patients, 31 metastases in the lungs were irradiated; with each of 33 patients, stage I non-small cell lung cancer (NSCLC) was subject to irradiation. The standard dose prescribed to the isocenter was 30 Gy with an axial safety margin of 10 mm and a longitudinal safety margin of 15 mm. The planning target volume (PTV) was defined using three CT scans with reference to the phases of respiration so that the movement span of the clinical target volume (CTV) was enclosed. RESULTS: The volume of the metastases (CTV) varied from 2.8 to 55.8 cm(3 )(median: 6.0 cm(3)) and the PTV varied from 12.2 to 184.0 cm(3 )(median: 45.0 cm(3)). The metastases ranged from 0.7 to 4.5 cm in largest diameter. The volume of the bronchial carcinomas varied from 4.2 to 125.4 cm(3)(median: 17.5 cm(3)) and the PTV from 15.6 to 387.3 cm(3 )(median: 99.8 cm(3)). The bronchial carcinomas ranged from 1.7 to 10 cm in largest diameter. Follow-up periods varied from 6.8 to 63 months (median: 22 months for metastases and 18 months for NSCLC). Local control was achieved with 94% of NSCLC and 87% of metastases. No serious symptomatic side effects were observed. According to the Kaplan-Meier method the overall survival probability rates of patients with lung metastases were as follows: 1 year: 97%, 2 years: 73%, 3 years: 42%, 4 years: 42%, 5 years: 42% (median survival: 26 months); of those with NSCLC: 1 year: 83%, 2 years: 63%, 3 years: 53%, 4 years: 39%: (median survival: 20.4 months). CONCLUSION: Non-fractionated single-dose irradiation of metastases in the lungs or of small, peripheral bronchial carcinomas is an effective and safe form of local treatment and might become a viable alternative to invasive techniques
Transport properties of copper phthalocyanine based organic electronic devices
Ambipolar charge carrier transport in Copper phthalocyanine (CuPc) is studied
experimentally in field-effect transistors and metal-insulator-semiconductor
diodes at various temperatures. The electronic structure and the transport
properties of CuPc attached to leads are calculated using density functional
theory and scattering theory at the non-equilibrium Green's function level. We
discuss, in particular, the electronic structure of CuPc molecules attached to
gold chains in different geometries to mimic the different experimental setups.
The combined experimental and theoretical analysis explains the dependence of
the mobilityand the transmission coefficient on the charge carrier type
(electrons or holes) and on the contact geometry. We demonstrate the
correspondence between our experimental results on thick films and our
theoretical studies of single molecule contacts. Preliminary results for
fluorinated CuPc are discussed.Comment: 18 pages, 16 figures; to be published in Eur. Phys. J. Special Topic
Quantum criticality and black holes
Many condensed matter experiments explore the finite temperature dynamics of
systems near quantum critical points. Often, there are no well-defined
quasiparticle excitations, and so quantum kinetic equations do not describe the
transport properties completely. The theory shows that the transport
co-efficients are not proportional to a mean free scattering time (as is the
case in the Boltzmann theory of quasiparticles), but are completely determined
by the absolute temperature and by equilibrium thermodynamic observables.
Recently, explicit solutions of this quantum critical dynamics have become
possible via the AdS/CFT duality discovered in string theory. This shows that
the quantum critical theory provides a holographic description of the quantum
theory of black holes in a negatively curved anti-de Sitter space, and relates
its transport co-efficients to properties of the Hawking radiation from the
black hole. We review how insights from this connection have led to new results
for experimental systems: (i) the vicinity of the superfluid-insulator
transition in the presence of an applied magnetic field, and its possible
application to measurements of the Nernst effect in the cuprates, (ii) the
magnetohydrodynamics of the plasma of Dirac electrons in graphene and the
prediction of a hydrodynamic cyclotron resonance.Comment: 12 pages, 2 figures; Talk at LT25, Amsterda
Interplant Communication of Tomato Plants through Underground Common Mycorrhizal Networks
Plants can defend themselves to pathogen and herbivore attack by responding to chemical signals that are emitted by attacked plants. It is well established that such signals can be transferred through the air. In theory, plants can also communicate with each other through underground common mycorrhizal networks (CMNs) that interconnect roots of multiple plants. However, until now research focused on plant-to-plant carbon nutrient movement and there is no evidence that defense signals can be exchanged through such mycorrhizal hyphal networks. Here, we show that CMNs mediate plant-plant communication between healthy plants and pathogen-infected tomato plants (Lycopersicon esculentum Mill.). After establishment of CMNs with the arbuscular mycorrhizal fungus Glomus mosseae between tomato plants, inoculation of ‘donor’ plants with the pathogen Alternaria solani led to increases in disease resistance and activities of the putative defensive enzymes, peroxidase, polyphenol oxidase, chitinase, β-1,3-glucanase, phenylalanine ammonia-lyase and lipoxygenase in healthy neighbouring ‘receiver’ plants. The uninfected ‘receiver’ plants also activated six defence-related genes when CMNs connected ‘donor’ plants challenged with A. solani. This finding indicates that CMNs may function as a plant-plant underground communication conduit whereby disease resistance and induced defence signals can be transferred between the healthy and pathogen-infected neighbouring plants, suggesting that plants can ‘eavesdrop’ on defence signals from the pathogen-challenged neighbours through CMNs to activate defences before being attacked themselves
Populations of planets in multiple star systems
Astronomers have discovered that both planets and binaries are abundant
throughout the Galaxy. In combination, we know of over 100 planets in binary
and higher-order multi-star systems, in both circumbinary and circumstellar
configurations. In this chapter we review these findings and some of their
implications for the formation of both stars and planets. Most of the planets
found have been circumstellar, where there is seemingly a ruinous influence of
the second star if sufficiently close (<50 AU). Hosts of hot Jupiters have been
a particularly popular target for binary star studies, showing an enhanced rate
of stellar multiplicity for moderately wide binaries (>100 AU). This was
thought to be a sign of Kozai-Lidov migration, however recent studies have
shown this mechanism to be too inefficient to account for the majority of hot
Jupiters. A couple of dozen circumbinary planets have been proposed around both
main sequence and evolved binaries. Around main sequence binaries there are
preliminary indications that the frequency of gas giants is as high as those
around single stars. There is however a conspicuous absence of circumbinary
planets around the tightest main sequence binaries with periods of just a few
days, suggesting a unique, more disruptive formation history of such close
stellar pairs.Comment: Invited review chapter, accepted for publication in "Handbook of
Exoplanets", ed. H. Deeg & J. A. Belmont
Joining S100 proteins and migration:for better or for worse, in sickness and in health
The vast diversity of S100 proteins has demonstrated a multitude of biological correlations with cell growth, cell differentiation and cell survival in numerous physiological and pathological conditions in all cells of the body. This review summarises some of the reported regulatory functions of S100 proteins (namely S100A1, S100A2, S100A4, S100A6, S100A7, S100A8/S100A9, S100A10, S100A11, S100A12, S100B and S100P) on cellular migration and invasion, established in both culture and animal model systems and the possible mechanisms that have been proposed to be responsible. These mechanisms involve intracellular events and components of the cytoskeletal organisation (actin/myosin filaments, intermediate filaments and microtubules) as well as extracellular signalling at different cell surface receptors (RAGE and integrins). Finally, we shall attempt to demonstrate how aberrant expression of the S100 proteins may lead to pathological events and human disorders and furthermore provide a rationale to possibly explain why the expression of some of the S100 proteins (mainly S100A4 and S100P) has led to conflicting results on motility, depending on the cells used. © 2013 Springer Basel
- …