A negative feedback between anthropogenic ozone pollution and enhanced ocean emissions of iodine

Naturally emitted from the oceans, iodine compounds efficiently destroy atmospheric ozone and reduce its positive radiative forcing effects in the troposphere. Emissions of inorganic iodine have been experimentally shown to depend on the deposition to the oceans of tropospheric ozone, whose concentrations have significantly increased since 1850 as a result of human activities. A chemistry-climate model is used herein to quantify the current ocean emissions of inorganic iodine and assess the impact that the anthropogenic increase in tropospheric ozone has had on the natural cycle of iodine in the marine environment since pre-industrial times. Our results indicate that the human-driven enhancement of tropospheric ozone has doubled the oceanic inorganic iodine emissions following the reaction of ozone with iodide at the sea surface. The consequent build-up of atmospheric iodine, with maximum enhancements of up to 70% with respect to pre-industrial times in continental pollution outflow regions, has in turn accelerated the ozone chemical loss over the oceans with strong spatial patterns. We suggest that this ocean-atmosphere interaction represents a negative geochemical feedback loop by which current ocean emissions of iodine act as a natural buffer for ozone pollution and its radiative forcing in the global marine environment.Fil: Prados Roman, C.. Consejo Superior de Investigaciones Científicas. Instituto de Química Física; EspañaFil: Cuevas, Carlos Alberto. Consejo Superior de Investigaciones Científicas. Instituto de Química Física; EspañaFil: Fernandez, Rafael Pedro. Consejo Superior de Investigaciones Científicas. Instituto de Química Física; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza; ArgentinaFil: Kinnison, Douglas E.. National Center For Atmospheric Research. Amospheric Chemistry División; Estados UnidosFil: Lamarque, Jean Francoise. National Center For Atmospheric Research. Amospheric Chemistry División; Estados UnidosFil: Saiz-lopez, Alfonso. Consejo Superior de Investigaciones Científicas. Instituto de Química Física; Españ

Impulsive phase transport

The transport of nonthermal electrons is explored. The thick-target electron beam model, in which electrons are presumed to be accelerated in the corona and typically thermalized primarily in the chromosphere and photosphere, is supported by observations throughout the electromagnetic spectrum. At the highest energies, the anisotropy of gamma-ray emission above 10 MeV clearly indicates that these photons are emitted by anisotropically-directed particles. The timing of this high-energy gamma-radiation with respect to lower-energy hard X-radiation implies that the energetic particles have short life-times. For collisional energy loss, this means that they are stopped in the chromosphere or below. Stereoscopic (two-spacecraft) observations at hard X-ray energies (up to 350 keV) imply that these lower-energy (but certainly nonthermal) electrons are also stopped deep in the chromosphere. Hard X-ray images show that, in spatially resolved flares whose radiation consists of impulsive bursts, the impulsive phase starts with X-radiation that comes mostly from the foot-points of coronal loops whose coronal component is outlined by microwaves

Search and analysis of giant radio galaxies with associated nuclei (SAGAN) -- I : New sample and multi-wavelength studies

We present the first results of a project called SAGAN, which is dedicated solely to the studies of relatively rare megaparsec-scale radio galaxies in the Universe, called giant radio galaxies (GRGs). We have identified 162 new GRGs primarily from the NVSS with sizes ranging from ~0.71 Mpc to 2.82 Mpc in the redshift range of ~0.03 - 0.95, of which 23 are hosted by quasars (giant radio quasars, GRQs). As part of the project SAGAN, we have created a database of all known GRGs, the GRG catalogue, from the literature (including our new sample); it includes 820 sources. For the first time, we present the multi-wavelength properties of the largest sample of GRGs. Our results establish that the distributions of the radio spectral index and the black hole mass of GRGs do not differ from the corresponding distributions of normal-sized radio galaxies (RGs). However, GRGs have a lower Eddington ratio (ER) than RGs. Using the mid-infrared data, we classified GRGs in terms of their accretion mode: either a high-power radiatively efficient high-excitation state, or a radiatively inefficient low-excitation state. We find that GRGs in high-excitation state statistically have larger sizes, stronger radio power, jet kinetic power, and higher ER than those in low-excitation state. Our analysis reveals a strong correlation between the ER and the scaled jet kinetic power, which suggests a disc-jet coupling. Our environmental study reveals that ~10% of all GRGs may reside at the centres of galaxy clusters, in a denser galactic environment, while the majority appears to reside in a sparse environment. We find that the probability of BCG as a GRG is quite low. We present new results for GRGs that range from black hole mass to large-scale environment properties. We discuss their formation and growth scenarios, highlighting the key physical factors that cause them to reach their gigantic size. Abridged.Comment: Accepted for publication in Astronomy & Astrophysics. 14 figures, 7 tables and 7 montages. Comments are welcome. "SAGAN Project website https://sites.google.com/site/anantasakyatta/sagan

Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery: a prospective observational study

Abstract Introduction Previous studies have documented a high frequency of endotoxemia associated with cardiopulmonary bypass (CPB). Endotoxemia may be responsible for some of the complications associated with cardiac surgery. The purpose of the study was to examine the prevalence of endotoxemia during cardiopulmonary bypass supported aortocoronary bypass grafting surgery (ACB) using a new assay, the Endotoxin Activity Assay (EAA), and explore the association between endotoxemia and post-operative infection. Methods The study was a single center prospective observational study measuring EAA during the perioperative period for elective ACB. Blood samples were drawn at induction of anesthesia (T1), immediately prior to release of the aortic cross-clamp (T2), and on the first post-operative morning (T3). The primary outcome was the prevalence of endotoxemia. Secondary outcomes assessed included infection rates, intensive care unit (ICU) and hospital length of stay. An EAA of < 0.40 units was interpreted as "low", 0.41 to 0.59 units as "intermediate", and ≥0.60 units as "high". Results A total of 57 patients were enrolled and 54 patients were analyzable. The mean EAA at T1 was 0.38 +/- 0.14, at T2 0.39 +/- 0.18, and at T3 0.33 +/- 0.18. At T2 only 13.5% (7/52) of patients had an EAA in the high range. There was a positive correlation between EAA and duration of surgery (P = 0.02). In patients with EAA ≥0.40 at T2, 26.1% (6/23) of patients developed post-operative infections compared to 3.5% (1/29) of those that had a normal EAA (P = 0.0354). Maximum EAA over the first 24 hours was also strongly correlated with risk of post-operative infection (P = 0.0276). Conclusions High levels of endotoxin occur less frequently during ACB than previously documented. However, endotoxemia is associated with a significantly increased risk of the development of post-operative infection. Measuring endotoxin levels during ACB may provide a mechanism to identify and target a high risk patient population

Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats.

OBJECTIVE Blockade of the CB1 receptor is one of the promising strategies for the treatment of obesity. Although antagonists suppress food intake and reduce body weight, the role of central versus peripheral CB1 activation on weight loss and related metabolic parameters remains to be elucidated. We therefore specifically assessed and compared the respective potential relevance of central nervous system (CNS) versus peripheral CB1 receptors in the regulation of energy homeostasis and lipid and glucose metabolism in diet-induced obese (DIO) rats. RESEARCH DESIGN AND METHODS Both lean and DIO rats were used for our experiments. The expression of key enzymes involved in lipid metabolism was measured by real-time PCR, and euglycemic-hyperinsulinemic clamps were used for insulin sensitivity and glucose metabolism studies. RESULTS Specific CNS-CB1 blockade decreased body weight and food intake but, independent of those effects, had no beneficial influence on peripheral lipid and glucose metabolism. Peripheral treatment with CB1 antagonist (Rimonabant) also reduced food intake and body weight but, in addition, independently triggered lipid mobilization pathways in white adipose tissue and cellular glucose uptake. Insulin sensitivity and skeletal muscle glucose uptake were enhanced, while hepatic glucose production was decreased during peripheral infusion of the CB1 antagonist. However, these effects depended on the antagonist-elicited reduction of food intake. CONCLUSIONS Several relevant metabolic processes appear to independently benefit from peripheral blockade of CB1, while CNS-CB1 blockade alone predominantly affects food intake and body weight

SAGAN -- III: New insights into giant radio quasars

Giant radio quasars (GRQs) are radio-loud active galactic nuclei (AGNs), propelling megaparsec-scale jets. In order to understand GRQs and their properties, we have compiled all known GRQs ("the GRQ catalogue"), and a subset of small (size <700 kpc) radio quasars (SRQs) from the literature. In this process, we have found 10 new FR-II GRQs, in the redshift range of 0.66 < z < 1.72, which we include in the GRQ catalogue. Using the above samples, we have carried out a systematic comparative study of GRQs and SRQs, using optical and radio data. Our results show that the GRQs and SRQs statistically have similar spectral index and black hole mass distributions. However, SRQs have higher radio core power, core dominance factor, total radio power, jet kinetic power and Eddington ratio compared to GRQs. On the other hand, when compared to giant radio galaxies (GRGs), GRQs have higher black hole mass and Eddington ratio. The high core dominance factor of SRQs is an indicator of them lying closer to the line of sight than GRQs. We also find a correlation of the accretion disc luminosity with the radio core and jet power of GRQs, which provides evidence for disc-jet coupling. Lastly, we find the distributions of Eddington ratios of GRGs and GRQs to be bi-modal, similar to that found in small radio galaxies (SRGs) and SRQs, which indicate that size is not strongly dependent on the accretion state. Using all of these, we provide a basic model for the growth of SRQs to GRQs.Comment: Accepted for publication in Astronomy & Astrophysics. 9 figures, and 2 tables. This is the third paper in the series. Comments are welcome. "SAGAN Project website this http https://sites.google.com/site/anantasakyatta/sagan