176 research outputs found
Repurposing literacy: the uses of Richard Hoggart for creative education
After 50 years, what are the implications of Uses of Literacy for educational modernisation, in the light of subsequent changes from 'read only' literacy to 'read-write' uses of multimedia? This chapter argues that a broad extension of popular literacy via consumer-created digital content offers not only emancipationist potential in line with Hoggart's own project, but also economic benefits via the dynamics of creative innovation. Multimedia 'popular entertainments' pose a challenge to formal education, but not in the way that Hoggart feared. Instead of producing 'tamed helots,' commercial culture may be outpacing formal schooling in promoting creative digital literacy via entrepreneurial and distributed learning. It may indeed be that those in need of a creative make-over are not teenagers but teachers
Screening for Group B Streptococcus: A Private Hospital's Experience
Objective. To assess the effect of universal screening and administration of intrapartum antibiotic prophylaxis to prevent early-onset neonatal GBS sepsis at a private tertiary care hospital since issuance of the 2002 CDC guidelines for preventing perinatal GBS disease. Methods. Retrospective analysis of women delivering between January 1, 2003 and December 31, 2004 at a private tertiary care hospital in Houston, Texas. The percentage of women screened, GBS positive women receiving intrapartum antibiotic prophylaxis, and infants developing early-onset GBS sepsis were determined. Results. 2,108 women delivered 2,135 infants with 1,874 (89%) screened for GBS. Of those screened, 1,322 (71%) tested negative and 552 (29%) tested positive for GBS. In this analysis of 2,135 infants, 3 (0.94 cases/1,000 live births) were diagnosed with invasive GBS sepsis. Conclusion. High rates of screening of pregnant women for GBS colonization and use of intrapartum antibiotic prophylaxis for GBS carriers can be achieved in a private tertiary care hospital setting. “Synopsis: High screening rates for group B streptococcus in a private tertiary care hospital reduce the incidence of maternal and early onset neonatal GBS infection.
Impact of circulating bacterial DNA in long-term glucose homeostasis in non-diabetic patients with HIV infection: cohort study
In HIV-infected patients, the damage in the gut mucosal immune system is not completely restored after antiretroviral therapy (ART). It results in microbial translocation, which could influence the immune and inflammatory response. We aimed at investigating the long-term impact of bacterial-DNA translocation (bactDNA) on glucose homeostasis in an HIV population. This was a cohort study in HIV-infected patients
whereby inclusion criteria were: patients with age >18 years, ART-naïve or on effective ART (<50 HIV-1 RNA copies/mL) and without diabetes or chronic hepatitis C. Primary outcome was the change in HbA1c (%). Explanatory variables at baseline were: bactDNA (qualitatively detected in blood samples by PCR [broad-range PCR] and gene 16SrRNA - prokaryote), ART exposure, HOMA-R and a dynamic test HOMACIGMA
[continuous infusion of glucose with model assessment], hepatic steatosis (hepatic triglyceride content -
1H-MRS), visceral fat / subcutaneous ratio and inflammatory markers. Fifty-four men (age 43.2 ± 8.3 years, BMI
24.9 ± 3 kg/m2, mean duration of HIV infection of 8.1 ± 5.3 years) were included. Baseline HbA1c was 4.4 ± 0.4% and baseline presence of BactDNA in six patients. After 8.5 ± 0.5 years of follow-up, change in HbA1c was
1.5 ± 0.47% in patients with BactDNA vs 0.87 ± 0.3% in the rest of the sample p < 0.001. The change in Hba1c was also influenced by protease inhibitors exposure, but not by baseline indices of insulin resistance, body composition, hepatic steatosis, inflammatory markers or anthropometric changes. In non-diabetic patients with HIV infection, baseline bacterial translocation and PI exposure time were the only factors associated with long-term impaired glucose homeostasis
Teaching DBT Skills to DACA Recipients and their Families: Findings from an ECHO Program
Deferred Action for Childhood Arrivals (DACA) offers temporary administrative relief from deportation for undocumented immigrant adolescents and young adults who were brought as children to the United States. Accordingly, DACA has contributed to creating a different landscape of opportunities for this group. However, DACA has been and continues to be highly contested in the national political climate. Threats to DACA give rise to considerable anxiety, fear, and distress among its recipients, who face significant barriers to accessing mental health care services. Thus, a group of psychologists partnered with a leading immigrant rights advocacy organization and formed a reciprocal collaboration to understand and meet the mental health needs of undocumented communities. A major focus of the collaboration is to foster learning and support members of the immigrant community in contributing to their own well-being. The collaborative developed and delivered a stand-alone web-based mental health education session to DACA recipients and their families and practitioners serving this population. The session presented the use of dialectical behavioral therapy skills, three emotion regulation and four distress tolerance skills, as a strength-based approach to managing painful emotions and distress. Session content was adapted to include culturally informed examples for each skill. Quantitative and qualitative findings show that those who participated in the web-based program benefited from the education received. Findings also underscored participants’ need for learning culturally sensitive coping strategies for managing stress. We provide recommendations on the delivery of culturally congruent healing interventions for immigrants with a focus on enhancing access among immigrant communities
Construção de usina de fertilizantes em sítio Ramsar, implementação de política pública para o cuidado e preservação, em Topolobampo Sinaloa, México
Este artigo apresenta o resultado de uma pesquisa e explica o problema atual da construção de uma usina de fertilizantes na baía de Topolobampo, Sinaloa, estabelecida pela Gás e Petroquímica de Ocidente, uma subsidiária mexicana da Holding Suizo - Alemana Proman, que gerará amônia anidra, insumo de fertilizantes, portanto, a necessidade de implementar uma proteção real baseada em políticas públicas focadas na preservação da referida baía, que está catalogado no acordo Ramsar. A construção da usina começou em 2014; mas os confrontos com moradores cancelou sua construção. Portanto, são detalhadas as afetações caso a construção da usina venha ocorrer, propondo a proteção da baía com base em políticas públicas para o benefício do referido local.El artículo presenta el resultado de una investigación y explica la problemática actual de la construcción de una planta de fertilizantes en la bahía de Topolobampo, Sinaloa, instaurada por Gas y Petroquímica de Occidente, empresa mexicana subsidiaria de Holding Suizo - Alemana Proman, misma que generará amoniaco anhidro insumo de fertilizantes, por lo anterior, la necesidad de implementar protección real con base en políticas públicas enfocadas a la preservación de dicha bahía, la cual es catalogada sitio Ramsar. La construcción de la planta comenzó en el año 2014; forjando confrontaciones con pobladores cancelando su construcción. Por lo anterior, se detallan las afectaciones en caso de realizarse la construcción de la planta, proponiendo protección a la bahía con base en políticas públicas en beneficio a dicho sitio. The article presents the result of an investigation and explains the current problems of the construction of a fertilizer plant in the bay of Topolobampo, Sinaloa, established by Gas y Petroquímica de Occidente, a Mexican subsidiary of the Swiss-German Holding Proman, which will generate anhydrous ammonia as a fertilizer input, and therefore, the need to implement real protection based on public policies focused on the preservation of the bay, which is a Ramsar site.
The construction of the plant began in 2014; forging confrontations with residents canceling its construction. Therefore, we detail the impacts in case of construction of the plant, proposing protection of the bay based on public policies for the benefit of the site
MicroRNAs and Drinking: Association between the Pre-miR-27a rs895819 Polymorphism and Alcohol Consumption in a Mediterranean Population
Recently, microRNAs (miRNA) have been proposed as regulators in the different processes involved in alcohol intake, and differences have been found in the miRNA expression profile in alcoholics. However, no study has focused on analyzing polymorphisms in genes encoding miRNAs and daily alcohol consumption at the population level. Our aim was to investigate the association between a functional polymorphism in the pre-miR-27a (rs895819 A>G) gene and alcohol consumption in an elderly population. We undertook a cross-sectional study of PREvencion con DIeta MEDiterranea (PREDIMED)-Valencia participants (n = 1007, including men and women aged 67 +/- 7 years) and measured their alcohol consumption (total and alcoholic beverages) through a validated questionnaire. We found a strong association between the pre-miR-27a polymorphism and total alcohol intake, this being higher in GG subjects (5.2 +/- 0.4 in AA, 5.9 +/- 0.5 in AG and 9.1 +/- 1.8 g/day in GG; p(adjusted) = 0.019). We also found a statistically-significant association of the pre-miR-27a polymorphism with the risk of having a high alcohol intake (> 2 drinks/day in men and > 1 in women): 5.9\% in AA versus 17.5\% in GG; p(adjusted) < 0.001. In the sensitivity analysis, this association was homogeneous for sex, obesity and Mediterranean diet adherence. In conclusion, we report for the first time a significant association between a miRNA polymorphism (rs895819) and daily alcohol consumption.This study was funded, by the Spanish Ministry of Health (Instituto de Salud Carlos III) and the Ministerio de Economia y Competitividad-Fondo Europeo de Desarrollo Regional (Projects CNIC-06/2007, RTIC G03/140, CIBER 06/03, PI06-1326, PI07-0954, PI11/02505, SAF2009-12304, AGL2010-22319-C03-03 and PRX14/00527), by the lUniversity Jaume I (Project P1-1B2013-54), by Contracts 53-K06-5-10 and 58-1950-9-001 from the U.S. Department of Agriculture Research Service, USA, by the Generalitat Valenciana (ACOMP2010-181, AP111/10, AP-042/11, ACOM2011/145, ACOMP/2012/190, ACOMP/2013/159 and ACOMP/213/165), and with the collaboration of the Real Colegio Complutense at Harvard University, Cambridge. MA, USA. Rocio Barragon's contract is funded by the Ayudas para la contratacion de personal investigador en formacion de caracter predoctoral, Programa ``VALencia Investigacion mas Desarrollo´´ (VALi+d). Conselleria d'Educacio, Investigacio, Cultura i Esport. Generalitat Valenciana, Spain (ACIF/2013/168).S
Jimmie
Peter Stuy vesant came from Holland and ruled Manhattan a while.Then the bally old Duke of YorkTook the jolly old isle!But today the town is owned by quite a different sort.She\u27s just a slip of a Tomboy kid,And they call her Jimmie for short.
REFRAINJimmie, just Jimmie. She\u27s a chip of old New YorkVagrant and whimmy, A dear little bluffin\u27 Ragamuffin One smile from JimmieAnd a host of glooms departThere\u27s a Paradise In those laughing eyes of Jimmie, just JimmieShe\u27ll haunt your heart. heart.
I have tried to think of other thingsSome diversion to find.But I\u27m sorry I must confess.I\u27ve a single tracked mind.My poor heart a hopeless prisoner. That will never be free.The smiling face of a Tomboy kid,Is all I ever can see
Imaging of changes in copper trafficking and redistribution in a mouse model of Niemann-Pick C disease using positron emission tomography
Niemann-Pick C disease (NPC) is an autosomal recessive lysosomal storage disorder resulting from mutations in the NPC1 (95% of cases) or NPC2 genes. Disturbance of copper homeostasis has been reported in NPC1 disease. In this study we have used whole-body positron emission tomography (PET) and brain electronic autoradiography with copper-64 (64Cu), in the form of the copper(II) bis(thiosemicarbazonato) complex 64Cu-GTSM, to image short-term changes in copper trafficking after intravenous injection in a transgenic mouse model of NPC1 disease. 64Cu-GTSM is taken up in all tissues and dissociates rapidly inside cells, allowing monitoring of the subsequent efflux and redistribution of 64Cu from all tissues. Significantly enhanced retention of 64Cu radioactivity was observed in brain, lungs and blood at 15 h post-injection in symptomatic Npc1−/− transgenic mice compared to wildtype controls. The enhanced retention of 64Cu in brain was confirmed by electronic autoradiography, particularly in the midbrain, thalamus, medulla and pons regions. Positron emission tomography imaging with 64Cu in selected chemical forms could be a useful diagnostic and research tool for the management and understanding of NPC1 disease
Detección de monensina por espectrofotometría en piensos para la alimentación del ganado vacuno
La incesante presión de la agricultura, así como la búsqueda de una mayor eficiencia en los sistemas ganaderos, ha conducido a un mayor uso de herramientas farmacológicas como estrategia para mejorar la rentabilidad de la ganadería. La Monensina (MN) es un antibiótico poliéter (PEs) del grupo de los ionóforos elaborado por un hongo, el Streptomyces cinnamonensi. El objetivo
de este trabajo es contar con un método de cuantificación de MN en pienso utilizando equipamiento de baja complejidad, disponibles en laboratorios veterinarios de análisis rutinarios, y que además permita realizar un mayor seguimiento en cuanto a la formulación de las dietas y sus componentes, evitando pérdidas tanto clínicas como subclínicas que afecten la rentabilidad del sistema ganadero.Se obtuvo un límite de detección (LOD) de 3 mg MN/Kg de alimento y un límite de cuantificación (LOQ) de 8 mg MN/Kg de alimento. La técnica es apropiada para medir MN en piensos en dosis normales de trabajo y en sobredosificaciones con un bajo costo de insumos y equipamiento.The incessant pressure of agriculture and the
search for greater efficiency in livestock systems,
has led to increased use of pharmacological tools
as a strategy to improve the profitability of livestock.
The monensin (MN) is a polyether antibiotic
(PEs) from the group of ionophores compounds
produced by a fungus, Streptomyces cinnamonensi.
This work is a communication of a simple
and reliable method of quantifying MN in animal
feed, using low complexity equipment available in
routine veterinary laboratories. Thus, a better
monitoring of the formulation of diets and their
components will be possible, avoiding both clinical
and subclinical losses which in the end affect
the profitability of the farming. The technique
resulted suitable for measuring MN in feed in normal
doses and overdoses working with low cost
supplies and equipment.Fil: Berneri, María Jimena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Area de Salud Pública Veterinaria; Argentina. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Departamento de Química. Área de Toxicología; ArgentinaFil: Miranda, Ariel Omar. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Anguil. Area de Salud Pública Veterinaria; ArgentinaFil: Frances, Oscar Alberto. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias; ArgentinaFil: Mastrantonio Garrido, Guido Enrique. Universidad Nacional de La Pampa. Facultad de Ciencias Exactas y Naturales. Departamento de Química. Área de Toxicología; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Ciencias Biológicas. Área de Toxicología; Argentin
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