Urban Refugees in Lebanon: Housing, Residency, and Wellbeing

Lebanon hosts over a million Syrian refugees in addition to other displaced groups. These refugees have gravitated to urban centres, putting significant pressure on local infrastructure and services. Living in close proximity to one another, hosts and refugees face significant challenges to their wellbeing. While some of these challenges are distinct, such as legal residency, others, such as housing are shared. Addressing these challenges should be a priority for national and municipal governments, and humanitarian and development agencies. Urban informal settlements, official Palestinian camps, and unofficial ‘gatherings’ are key localities for intervention.Netherlands Organisation for Scientific Research-Foundation for the Advancement of Tropical Researc

lin-12 Notch functions in the adult nervous system of C. elegans

BACKGROUND: Notch signaling pathways are conserved across species and traditionally have been implicated in cell fate determination during embryonic development. Notch signaling components are also expressed postdevelopmentally in the brains of adult mice and Drosophila. Recent studies suggest that Notch signaling may play a role in the physiological, rather than developmental, regulation of neurons. Here, we investigate a new non-developmental role for Caenorhabditis elegans lin-12 Notch signaling in neurons regulating the spontaneous reversal rate during locomotion. RESULTS: The spontaneous reversal rate of C. elegans during normal locomotion is constant. Both lin-12 gain and loss of function mutant animals had significantly increased reversal rates compared to wild type controls. These defects were caused by lin-12 activity, because the loss of function defect could be rescued by a wild type lin-12 transgene. Furthermore, overexpression of lin-12 recapitulated the gain-of-function defect. Increasing or decreasing lin-12 activity in the postdevelopmental adult animal was sufficient to rapidly and reversibly increase reversals, thereby excluding a developmental role for lin-12. Although lin-12 is expressed in the vulval and somatic gonad lineages, we find that these tissues play no role in regulating reversal rates. In contrast, altering lin-12 activity specifically in the nervous system was sufficient to increase reversals. These behavioral changes require components of the canonical lin-12 signaling cascade, including the ligand lag-2 and the transcriptional effector lag-1. Finally, the C. elegans AMPA/kainate glutamate receptor homolog glr-1 shows strong genetic interactions with lin-12, suggesting that glr-1 and/or other glutamate gated channels may be targets of lin-12 regulation. CONCLUSION: Our results demonstrate a neuronal role for lin-12 Notch in C. elegans and suggest that lin-12 acutely regulates neuronal physiology to modulate animal behavior, without altering neuronal cell fate specification or neurite outgrowth. This is consistent with a role for Notch signaling in neurological disease with late onset symptoms

A ring of instantons inducing a monopole loop

We consider the superposition of infinitely many instantons on a circle in R^4. The construction yields a self-dual solution of the Yang-Mills equations with action density concentrated on the ring. We show that this configuration is reducible in which case magnetic charge can be defined in a gauge invariant way. Indeed, we find a unit charge monopole (worldline) on the ring. This is an analytic example of the correlation between monopoles and action/topological density, however with infinite action. We show that both the Maximal Abelian Gauge and the Laplacian Abelian Gauge detect the monopole, while the Polyakov gauge does not. We discuss the implications of this configuration.Comment: 11 pages, 1 figur

Contested Public Authority in Marginal Urban Areas: Challenges for Humanitarians

In urban contexts where multiple governance actors compete for authority, a clearer approach is needed on whether and how to engage these various actors in order to reach the most vulnerable host and refugee populations

Stochastic Route Planning in Public Transport

Journey planning is a key process in public transport, where travelers get informed how to make the best use of a given public transport system for their individual travel needs. A common trait of most available journey planners is that they assume deterministic travel times, but vehicles in public transport often deviate from their schedule. The present paper investigates the problem of finding journey plans in a stochastic environment. To fully exploit the flexibility inherent in multi-service public transport systems, we propose to use the concept of a routing policy instead of a linear journey plan. A policy is a state-dependent routing advice which specifies a set of services at each location from which the traveler is recommended to take the one that arrives first. We consider current time dependent policies, that is, when the routing advice at a given location is based solely on the current time. We propose two heuristic solutions that find routing policies that perform better than deterministic journey plans. A numerical comparison shows the achievable gains when applying the different heuristic policies based on extensive simulations on the public transport network of Budapest. The results show that the probability of arriving on time to a given destination can be significantly improved by following a policy instead of a linear travel plan

Instantons and Gribov Copies in the Maximally Abelian Gauge

We calculate the Faddeev-Popov operator corresponding to the maximally Abelian gauge for gauge group SU(N). Specializing to SU(2) we look for explicit zero modes of this operator. Within an illuminating toy model (Yang-Mills mechanics) the problem can be completely solved and understood. In the field theory case we are able to find an analytic expression for a normalizable zero mode in the background of a single `t Hooft instanton. Accordingly, such an instanton corresponds to a horizon configuration in the maximally Abelian gauge. Possible physical implications are discussed.Comment: 31 pages, 8 figures, v3: references adde

Enhancing the Value of Rural Towns through Ecosystem Interventions:A report for the Local Enterprise Partnerships of Lancashire and Cumbria, to inform ecosystem approaches to place-based policy

This in-depth case study of a Rural Hub Town delivers new evidence for place makers, with insights that have resonance across the 182 Hub Towns in England. As the UK government performs its ‘pivot to towns’ through multiple strands of place-based policy, we need to better understand these critical sites. Hub Towns, as identified by DEFRA and the ONS, play a critical role at the nexus of urban and rural economies and society, and need to be better studied and understood. We break new ground by unpacking the ways in which economy, culture and environment can come together to support thriving communities and economic growth in Hub Towns. Building on a robust core of academic research, we draw together a substantial body of data including 49 interviews with key stakeholders in a single town, along with public engagement data (collected by the District Council) constituting the comments and feedback from 1,663 individuals and organisations. By studying the entire rural town ecosystem, we reveal how Place Value is created. Furthermore, we propose two economic, one cultural, and one environment related intervention that each deliver significant, cascading benefits through the town and its rural hinterland. Taken together, these interventions represent a cohesive approach to Rural Hub Town development, applicable in this site, whilst offering a start point for ecosystem-level research and policy making across the other Hub Towns

Parents’ views on how health professionals should work with them now to get the best for their child in the future

Background  Pregnancy and the first years of life are important times for future child well-being. Early identification of families and children who might be likely to experience poorer outcomes could enable health professionals and parents to work together to promote each child’s well-being. Little is known about the acceptability and feasibility of such an approach to parents. Objective  To investigate parents’ views about how health professionals should identify and work with families who may benefit from additional input to maximize their children’s future health and well-being. Design  A qualitative study using focus groups. Setting and participants  Eleven focus groups were conducted with a total of 54 parents; 42 mothers and 12 fathers living in the north of England. Results  Parents welcomed the idea of preventive services. They strongly believed that everyone should have access to services to enhance child well-being whilst recognizing that some families need additional support. Making judgements about who should receive additional services based on specific criteria evoked powerful emotions because of the implication of failure. Parents projected a belief in themselves as ‘good parents’ even in adverse circumstances. Conclusions  Targeted additional preventive services can be acceptable and welcome if health professionals introduce them sensitively, in the context of an existing relationship, providing parents are active participants

Monopole characteristics in various Abelian gauges

Renormalization group (RG) smoothing is employed on the lattice to investigate and to compare the monopole structure of the SU(2) vacuum as seen in different gauges (maximally Abelian (MAG), Polyakov loop (PG) and Laplacian gauge (LG)). Physically relevant types of monopoles (LG and MAG) are distinguished by their behavior near the deconfining phase transition. For the LG, Abelian projection reproduces well the gauge independent monopole structure encoded in an auxiliary Higgs field. Density and localization properties of monopoles, their non-Abelian action and topological charge are studied. Results are presented confirming the Abelian dominance with respect to the non-perturbative static potential for all gauges considered.Comment: 36 pages, 12 figure

Genetic factors predict hybrid formation in the British flora

Natural hybridization can have a profound evolutionary impact, with consequences ranging from the extinction of rare taxa to the origin of new species. Natural hybridization is particularly common in plants; however, our understanding of the general factors that promote or prevent hybridization is hampered by the highly variable outcomes in different lineages. Here, we quantify the influence of different predictors on hybrid formation across species from an entire flora. We combine estimates of hybridization with ecological attributes and a new species-level phylogeny for over 1,100 UK flowering plant species. Our results show that genetic factors, particularly parental genetic distance, as well as phylogenetic position and ploidy, are key determinants of hybrid formation, whereas many other factors such as range overlap and genus size explain much less variation in hybrid formation. Overall, intrinsic genetic factors shape the evolutionary and ecological consequences of natural hybridization across species in a flora