HSE Management for a Sound Work Environment: Strategies for Improving Health Safety and Environmental Indicators through Ergonomic Design Thinking

Ergonomic Design Thinking (EDT) is a project management methodology that takes advantage of two important concepts or themes in carrying out project actions. The first is Design Thinking itself, a project management approach originally proposed by Tim Brown, who knew beforehand the full potential of design tools, techniques and maybe we should add idiosyncrasies. Designers have “their own way” of following through and carrying out issues such as deadlines and sequences, for example. This logic is similar to another important theme: ergonomics. The main objective of ergonomics is adapting work systems to workers themselves. By doing so, its professionals dig deep into the social technical fabric of a workplace and use recurrent and iterative strategies in order to search for a perfect fit for a given workstation. EDT as a modeling guide for workspace projects have been used in Brazil for quite some time. This text outlines an interesting experience in which EDT was used as a conception tool in building a new health safety and environmental (HSE) management system model for construction sites. A real case–an ongoing construction work–was used to contextualize the experiment and better define the various instruments of this HSE model. Due to the work environment and predominant job characteristics available, the EDT approach did quite well in terms of serving its project management purpose, as it was confirmed when the new system became fully functional

Political-Pedagogical Character of the Collective Actions of the Popular Bars

Barrismo is a complex phenomenon and cannot be defined universally. Social representation is based on deficient conceptions that relate it to the use of psychoactive substances and violence. This article presents qualitative research evidence based on the epistemological assumptions of social constructionism, a hermeneutical phenomenological design and the use of qualitative interview and documentary and audiovisual review, to understand the political-pedagogical character of the collective actions of the popular bars of the city of Medellín, Colombia, as practices that contribute to the transformation of the territories. Categories found: i. Bars as popular movements: transition from the brave bar to the popular bar, and ii. Collective actions: Barrismo Social. The bars have gone from rough bars to popular bars, from political and critical reflexivity, with collective actions for the transformation of the territories, which transcends the experience of stigma and social prejudice

Differential Effects of Temperature and Mosquito Genetics Determine Transmissibility of Arboviruses by Aedes aegypti in Argentina

Aedes aegypti (L.) (Diptera: Culicidae) have a global distribution and are the primary vector of a number of mosquito-borne viruses responsible for epidemics throughout the Americas. As in much of South America, the threat from pathogens including dengue virus (DENV; Flaviviridae, Flavivirus) and chikungunya virus (CHIKV; Togaviridae, Alphavirus) has increased in Argentina in recent years. The complexity of transmission cycles makes predicting the occurrence and intensity of arbovirus outbreaks difficult. To gain a better understanding of the risk of DENV and CHIKV in Argentina and the factors influencing this risk, we evaluated the role of population and temperature in the vector competence and vectorial capacity (VC) of Ae. aegypti from geographically and ecologically distinct locations. Our results demonstrate that intrinsic and extrinsic factors including mosquito population, viral species, and temperature significantly influence both vector competence and overall VC of Ae. aegypti in Argentina, yet also that the magnitude of these influences is highly variable. Specifically, results suggest that CHIKV competence is more dependent on mosquito genetics than is DENV competence, whereas temperature has a greater effect on DENV transmission. In addition, although there is an overall positive correlation between temperature and competence for both viruses, there are exceptions to this for individual virus?population combinations. Together, these data establish large variability in VC for these pathogens among distinct Ae. aegypti populations in Argentina and demonstrate that accurate assessment of arbovirus risk will require nuanced models that fully consider the complexity of interactions between virus, temperature, mosquito genetics, and hosts.Fil: Ciota, Alexander T.. Wadsworth Center. State of New York Department of Health; Estados UnidosFil: Chin, Pamela A.. Wadsworth Center. State of New York Department of Health; Estados UnidosFil: Ehrbar, Dylan J.. Wadsworth Center. State of New York Department of Health; Estados UnidosFil: Micieli, Maria Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Fonseca, Dina M.. Center For Vector Biology, Rutgers University; Estados UnidosFil: Kramer, Laura D.. Wadsworth Center. State of New York Department of Health; Estados Unido

Comparative analysis of the child welfare systems of Portugal and Galician

Introdução: O sistema de proteção deve ser adaptado às necessidades específicas de dois jovens. Investigações anteriores indicam conveniência da administração de traçar políticas que facilitam a integração. Objetivo: Comparar as respostas que Galiza e Portugal dão às necessidades das crianças em situação de vulnerabilidade enquadradas no sistema de proteção. Métodos: Realizou-se uma análise das fontes estatísticas oficiais dos governos de Portugal, Espanha e da comunidade autónoma da Galiza. Resultados: Apontam a necessidade de reduzir, em ambos os países, o acolhimento residencial, priorizando a permanência nas famílias de acolhimento, especialmente no caso de Portugal. A família biológica, na qual a medida de proteção teve origem, é o principal destino após a saída do sistema proteção. Conclusão: Verificaram-se ainda défices de vagas nos recursos residenciais especializados em trabalhar o processo de transição para vida adulta.Introduction: The protection system must still adapt protective action to the specific needs of youth. Literature on the issue has indicated that the administration should design policies that facilitate the integration of vulnerable youth. Objetive: To compares Galiza and Portugal's response to the needs of vulnerable children who have an administrative protection case file. Methods: A analyze of the official statistical sources of the governments of Portugal, Spain, and the autonomous community of Galicia is carried out. Results: The results show the need to reduce residential care in both countries, giving priority to fixed residence in host families, especially in the case of Portugal. The biological family in which the protective measure originated is the main destination after leaving the protection system. Conclusion: A lack in places in residential resources specialized in addressing the process of transition to adult life are noted.info:eu-repo/semantics/publishedVersio

Isolation of a laccase-coding gene from the lignin-degrading fungus Phlebia brevispora BAFC 633 and heterologous expression in Pichia pastoris

Aims: Isolate and characterize a laccase-encoding gene (lac I) of Phlebia brevispora BAFC 633, as well as cloning and expressing cDNA of lac I in Pichia pastoris. And to obtain a purified and characterized recombinant laccase to analyse the biotechnological application potential. Methods and Results: Lac I was cloned and sequenced, it contains 2447 pb obtained by PCR and long-distance inverse PCR. Upstream of the structural region of the laccase gene, response elements such as metals, antioxidants, copper, nitrogen and heat shock were found. The coding region consisted of a 1563-pb ORF encoding 521 amino acids. Lac I was functionally expressed in P. pastoris and it was shown that the gene cloned using the α-factor signal peptide was more efficient than the native signal sequence, in directing the secretion of the recombinant protein. Km and highest kcat/Km values towards ABTS, followed by 2,6-dimethylphenol, were similar to other laccases. Lac I showed tolerance to NaCl and solvents, and nine synthetic dyes could be degraded to different degrees. Conclusions: Lac I-encoding gene could be successfully sequenced having cis-acting elements located at the regulatory region. It was found that lac I cDNA expressed in P. pastoris using the α-factor signal peptide was more efficient than the native signal sequence. The purified Lac I exhibited high tolerance towards NaCl and various solvents and degraded some recalcitrant synthetic dyes. Significance and Impact of the Study: The cis-acting elements may be involved in the transcriptional regulation of laccase gene expression. These results may provide a further insight into potential ways of optimizing fermentation process and also open new frontiers for engineering strong promoters for laccase production. The Lac I stability in chloride and solvents and broad decolorization of synthetic dyes are important for its use in organic synthesis work and degradation of dyes from textile effluents respectively.Fil: Fonseca, Maria Isabel. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Molina, Melisa Antonella. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Winnik, D. L.. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; ArgentinaFil: Busi, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Centro de Estudios Fotosintéticos y Bioquímicos. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Centro de Estudios Fotosintéticos y Bioquímicos; ArgentinaFil: Fariña, Julia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: Villalba, Laura. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Zapata, Pedro Dario. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Desenvolvimento e validação de instrumento para avaliar a ludicidade de jogos em saúde

OBJECTIVE Developing and validating an instrument to evaluate the playfulness of games in health education contexts. METHODOLOGY A methodological, exploratory and descriptive research, developed in two stages: 1. Application of an open questionnaire to 50 graduate students, with content analysis of the answers and calculation of Kappa coefficient for defining items; 2. Procedures for construction of scales, with content validation by judges and analysis of the consensus estimate byContent Validity Index(CVI). RESULTS 53 items regarding the restless character of the games in the dimensions of playfulness, the formative components of learning and the profiles of the players. CONCLUSION Ludicity can be assessed by validated items related to the degree of involvement, immersion and reinvention of the subjects in the game along with the dynamics and playability of the game.OBJETIVO Elaborar y validar un instrumento para la evaluación de la ludicidad de juegos en contextos educativos de salud. MÉTODO Investigación metodológica, exploratoria y descriptiva, desarrollada en dos etapas: 1. aplicación de cuestionario abierto a 50 estudiantes universitarios, con análisis de contenido de las respuestas y cómputo del coeficiente Kappa para cierre de los ítems; 2. procedimientos de construcción de escalas, con validación de contenido mediante análisis de los jueces y estimación de consenso por el Content Validity Index(CVI). RESULTADOS Se validaron 53 ítems acerca del carácter irrequieto de los juegos en las dimensiones de la ludicidad, de los componentes formativos del aprendizaje y del perfil de los jugadores. CONCLUSIÓN La ludicidad puede ser evaluada por ítems validados relacionados con el grado de involucración, inmersión y reinvención de los sujetos en el partido, al lado de la dinámica y la jugabilidad del juego.OBJETIVO Elaborar e validar um instrumento para a avaliação da ludicidade de jogos em contextos educativos da saúde. MÉTODO Pesquisa metodológica, exploratória e descritiva, desenvolvida em duas etapas: 1. aplicação de questionário aberto a 50 graduandos, com análise de conteúdo das respostas e cálculo do coeficiente Kappa para fechamento dos itens; 2. procedimentos de construção de escalas, com validação de conteúdo mediante análise dos juízes e estimativa de consenso pelo Content Validity Index(CVI). RESULTADOS Foram validados 53 itens acerca do caráter irrequieto dos jogos nas dimensões da ludicidade, dos componentes formativos da aprendizagem e do perfil dos jogadores. CONCLUSÃO A ludicidade pode ser avaliada por itens validados relacionados ao grau de envolvimento, de imersão e de reinvenção dos sujeitos na partida, ao lado da dinâmica e da jogabilidade do jogo

Estudio para la implantación de Programas en Inglés en los títulos de grado de la ETSI Agrónomos de la Universidad Politécnica de Madrid

Universities are offering more and more courses and programmes in an additional language. At HEPCLIL, therefore, we would like to debate the methodological im - plications of these changes, giving voice to practical classroom experiences and initiatives. We would also like to act as a platform for cutting-edge research on CLIL in higher education. What impact does teaching in an additional language have on content or language learning? What are the effects on teachers and stu - dents in higher education

Interactions between hypoxia tolerance and food deprivation in Amazonian oscars, Astronotus ocellatus

Oscars are often subjected to a combination of low levels of oxygen and fasting during nest-guarding on Amazonian floodplains. We questioned whether this anorexia would aggravate the osmo-respiratory compromise. We compared fed and fasted oscars (1014 days) in both normoxia and hypoxia (1020 Torr, 4 h). Routine oxygen consumption rates (MO2) were increased by 75% in fasted fish, reflecting behavioural differences, whereas fasting improved hypoxia resistance and critical oxygen tensions (Pcrit) lowered from 54 Torr in fed fish to 34 Torr when fasting. In fed fish, hypoxia reduced liver lipid stores by approximately 50% and total liver energy content by 30%. Fasted fish had a 50% lower hepatosomatic index, resulting in lower total liver protein, glycogen and lipid energy stores under normoxia. Compared with hypoxic fed fish, hypoxic fasted fish only showed reduced liver protein levels and even gained glycogen (+50%) on a per gram basis. This confirms the hypothesis that hypoxia-tolerant fish protect their glycogen stores as much as possible as a safeguard for more prolonged hypoxic events. In general, fasted fish showed lower hydroxyacylCoA dehydrogenase activities compared with fed fish, although this effect was only significant in hypoxic fasted fish. Energy stores and activities of enzymes related to energy metabolism in muscle or gills were not affected. Branchial Na+ uptake rates were more than two times lower in fed fish, whereas Na+ efflux was similar. Fed and fasted fish quickly reduced Na+ uptake and efflux during hypoxia, with fasting fish responding more rapidly. Ammonia excretion and K+ efflux were reduced under hypoxia, indicating decreased transcellular permeability. Fasted fish had more mitochondria-rich cells (MRC), with larger crypts, indicating the increased importance of the branchial uptake route when feeding is limited. Gill MRC density and surface area were greatly reduced under hypoxia, possibly to reduce ion uptake and efflux rates. Density of mucous cells of normoxic fasted fish was approximately fourfold of that in fed fish. Overall, a 1014 day fasting period had no negative effects on hypoxia tolerance in oscars, as fasted fish were able to respond more quickly to lower oxygen levels, and reduced branchial permeability effectively. © 2013. Published by The Company of Biologists Ltd

BENEFÍCIOS DA MUSICOTERAPIA EM PACIENTES COM DOENÇA DE ALZHEIMER

Introduction: Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by a decline in cognitive and behavioral functions due to progressive posterior atrophy, particularly of the medial temporal lobes. Music therapy consists of applying music and its elements (melody, rhythm, harmony, and sound) by qualified professionals, and can be applied actively or passively. Objective: This study aims to evaluate the evidence on the use of music therapy in patients affected by Alzheimer's disease. Methodology: This study is an integrative literature review, where the main databases were used (Medline, Scielo, Web of Science, SCOPUS) using the terms "music therapy", "Alzheimer's disease" and "neurology", combined by Boolean operators. Results and discussion: It was possible to observe that music therapy is beneficial as a non-drug adjuvant treatment in patients with AD, by proving benefits related to the reduction of stress, anxiety, depression, and improvements related to cognition and psychosocial status.  Conclusion: Therefore, it is concluded that music therapy is effective in varying degrees of cognitive impairment in Alzheimer's disease, particularly leading to cognitive and psychosocial improvements. Further, studies with larger populations should be done to obtain large-scale results. La enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa y progresiva caracterizada por una disminución de las funciones cognitivas y conductuales debido a la atrofia posterior progresiva, en particular de los lóbulos temporales mediales. La musicoterapia consiste en la aplicación de la música y sus elementos (melodía, ritmo, armonía y sonido) por profesionales cualificados, y puede aplicarse de forma activa o pasiva. Este estudio tiene como objetivo evaluar la evidencia sobre el uso de la musicoterapia en pacientes afectados por la enfermedad de Alzheimer. El presente estudio es una revisión integradora de la literatura, donde las principales bases de datos (Medline, Scielo, Web of Science, SCOPUS) fueron utilizadas utilizando los términos "musicoterapia", "enfermedad de Alzheimer" y "neurología", combinados entre sí por operadores booleanos. Fue posible observar que la musicoterapia es beneficiosa como tratamiento adyuvante no farmacológico en pacientes con EA, al demostrar los beneficios relacionados con la disminución del estrés, la ansiedad, la depresión y las mejoras relacionadas con la cognición y el estado psicosocial. Por lo tanto, se concluye que la musicoterapia es efectiva en diversos grados de deterioro cognitivo en la enfermedad de Alzheimer, lo que particularmente conduce a mejoras cognitivas y psicosociales. Además, los estudios con una población más grande deben llevarse a cabo de tal manera que se obtengan resultados a gran escala.Introdução: A doença de Alzheimer (DA) é uma doença neurodegenerativa e progressiva, caracterizada por um declínio das funções cognitivas e comportamentais devido a uma atrofia posterior progressiva, em particular dos lobos temporais mediais. A musicoterapia consiste na aplicação de música e seus elementos (melodia, ritmo, harmonia e som) por profissionais qualificados, podendo ser aplicada de forma ativa ou passiva. Objetivo: Esse estudo tem como objetivo avaliar as evidências sobre o uso da musicoterapia em pacientes acometidos pela doença de Alzheimer. Metodologia: O presente estudo é uma revisão integrativa de literatura, onde foram utilizadas as principais bases de dados (Medline, Scielo, Web of Science, SCOPUS) usando os termos “musicoterapia”, “doença de Alzheimer” e “neurologia”, entre os anos de 2010 e 2022, combinados entre si por operadores booleanos. Resultados e discussão: Foi possível observar que a musicoterapia é benéfica como tratamento adjuvante não medicamentoso em pacientes com DA, ao provar os benefícios relacionados à diminuição do estresse, ansiedade, depressão e melhoras relacionadas à cognição e estado psicossocial. Conclusão: Portanto, conclui-se que a musicoterapia é eficaz em variados graus de acometimento cognitivo na doença de Alzheimer, particularmente levando a melhorias cognitivas e psicossociais. Mais além, devem ser feitos estudos com maior população para que sejam obtidos resultados em larga escala.Introdução: A doença de Alzheimer (DA) é uma doença neurodegenerativa e progressiva, caracterizada por um declínio das funções cognitivas e comportamentais devido a uma atrofia posterior progressiva, em particular dos lobos temporais mediais. A musicoterapia consiste na aplicação de música e seus elementos (melodia, ritmo, harmonia e som) por profissionais qualificados, podendo ser aplicada de forma ativa ou passiva. Objetivo: Esse estudo tem como objetivo avaliar as evidências sobre o uso da musicoterapia em pacientes acometidos pela doença de Alzheimer. Metodologia: O presente estudo é uma revisão integrativa de literatura, onde foram utilizadas as principais bases de dados (Medline, Scielo, Web of Science, SCOPUS) usando os termos “musicoterapia”, “doença de Alzheimer” e “neurologia”, entre os anos de 2010 e 2022, combinados entre si por operadores booleanos. Resultados e discussão: Foi possível observar que a musicoterapia é benéfica como tratamento adjuvante não medicamentoso em pacientes com DA, ao provar os benefícios relacionados à diminuição do estresse, ansiedade, depressão e melhoras relacionadas à cognição e estado psicossocial. Conclusão: Portanto, conclui-se que a musicoterapia é eficaz em variados graus de acometimento cognitivo na doença de Alzheimer, particularmente levando a melhorias cognitivas e psicossociais. Mais além, devem ser feitos estudos com maior população para que sejam obtidos resultados em larga escala