3,594 research outputs found

    The best loved story of all time: overcoming all obstacles to be reunited, evoking kama muta

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    ANALISIS PERENCANAAN PENGADAAN OBAT ANTIBIOTIK BERDASARKAN ANALISIS ABC INDEKS KRITIS DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH LUWUK

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    ABSTRACT Pharmaceutical supply services in hospitals should be performed on the basis of the functions of logistics management, one of which is planning and procurement. Too little procurement can lead to out of stock outs, that is, the situation in which the required pharmaceutical supply is empty so that demand cannot be met, in which case it causes a loss to the hospital. To avoid the occurrence of stock out it must be done ABC Analysis Critical Index so it can be known which drug becomes a priority. This study aims to analyze the planning and procurement of antibiotic drugs based on ABC analysis of Critical Index at Pharmacy Installation of Luwuk Regional Public Hospital by using qualitative and quantitative descriptive method. The results showed that of the 40 types of antibiotics in which 3 types of drugs (7.50%) were group A, 19 types of drugs (47.50%) were group B, and 18 types of drugs (45.00%) were included in group C. Using of this ABC Analysis Critical Index can help the hospital in planning the procurement of medicines by taking into account the value of usage, investment value, and drug criticality. Keywords: Planning, Procurement, ABC Analysis Critical Index, Antibiotic. ABSTRAK Pelayanan persediaan farmasi di rumah sakit harus dilakukan berdasarkan fungsi-fungsi dari manajemen logistik, salah satunya perencanaan dan pengadaan. Pengadaan yang terlalu sedikit dapat menyebabkan terjadinya stock out, yaitu keadaan dimana persediaan farmasi yang dibutuhkan kosong sehingga permintaan tidak dapat dipenuhi, pada keadaan ini menyebabkan kerugian bagi rumah sakit. Untuk menghindari terjadinya stock out maka harus dilakukan Analisis ABC Indeks Kritis sehingga dapat diketahui obat mana yang menjadi prioritas. Penelitian ini bertujuan untuk menganalisis perencanaan dan pengadaan obat antibiotik berdasarkan analisis ABC Indeks Kritis di Instalasi Farmasi Rumah Sakit Umum Daerah Luwuk dengan menggunakan metode deskriptif kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa dari 40 jenis obat antibiotik terdapat, 3 jenis obat (7.50%) merupakan kelompok A, 19 jenis obat (47.50%) merupakan kelompok B, dan 18 jenis obat (45.00%)  termasuk dalam kelompok C. Penggunaan Analisis ABC Indeks Kritis ini dapat membantu pihak rumah sakit dalam merencanakan pengadaan obat dengan memperhatikan nilai pemakaian, nilai investasi, dan nilai kekritisan obat. Kata Kunci : Perencanaan, Pengadaan, Analisis ABC Indeks Kritis, Antibioti

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    Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria

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    Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation. They differed in several respects: electronmicroscopic appearance, phospholipid and cytochrome contents, electrophoretic behaviour of proteins and enzymatic activities. Three types of inner membrane fractions were isolated. The first type is characterized by a high activity of metal chelatase, low activities of succinate-cytochrome c reductase and of glycerolphosphate dehydrogenase, as well as by a high phospholipid content and low contents of cytochromes aa3 and b. The second type displays maximal activities of glycerolphosphate dehydrogenase and metal chelatase, but contains relatively little cytochromes and has low succinate-cytochrome c reductase activity. The third type exhibits highest succinate-cytochrome c reductase activity, a high metal chelatase activity and highest cytochrome contents. However, this fraction was low in both glycerolphosphate dehydrogenase activity and phospholipid content. This fraction was also richest in the following enzyme activities: cytochrome oxidase, oligomycin-sensitive ATPase, proline oxidase, 3-hydroxybutyrate dehydrogenase and rotenone-sensitive NADH-cytochrome c reductase. Amino acid incorporation in vitro and in vivo in the presence of cycloheximide occurs predominantly into inner membrane fractions from the second type. These data suggest that the inner membrane is composed of differently organized parts, and that polypeptides synthesized by mitochondrial ribosomes are integrated into specific parts of the inner membrane

    Lunar In Situ Materials-Based Surface Structure Technology Development Efforts at NASA/MSFC

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    For long-duration missions on other planetary bodies, the use of in situ materials will become increasingly critical. As man's presence on these bodies expands, so must the structures to accommodate them, including habitats, laboratories, berms, radiation shielding for surface reactors, garages, solar storm shelters, greenhouses, etc. The use of in situ materials will significantly offset required launch upmass and volume issues. Under the auspices of the In Situ Fabrication & Repair (ISFR) Program at NASA/Marshall Space Flight Center (MSFC), the Surface Structures project has been developing materials and construction technologies to support development of these in situ structures. This paper will report on the development of several of these technologies at MSFC's Prototype Development Laboratory (PDL). These technologies include, but are not limited to, development of extruded concrete and inflatable concrete dome technologies based on waterless and water-based concretes, development of regolith-based blocks with potential radiation shielding binders including polyurethane and polyethylene, pressure regulation systems for inflatable structures, production of glass fibers and rebar derived from molten lunar regolith simulant, development of regolithbag structures, and others, including automation design issues. Results to date and lessons learned will be presented, along with recommendations for future activities

    Beyond Prejudice as Simple Antipathy: Hostile and Benevolent Sexism Across Cultures

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    The authors argue that complementary hostile and benevolent componen:s of sexism exist ac ro.ss cultures. Male dominance creates hostile sexism (HS). but men's dependence on women fosters benevolent sexism (BS)-subjectively positive attitudes that put women on a pedestal but reinforce their subordination. Research with 15,000 men and women in 19 nations showed that (a) HS and BS are coherenl constructs th at correlate positively across nations, but (b) HS predicts the ascription of negative and BS the ascription of positive traits to women, (c) relative to men, women are more likely to reject HS than BS. especially when overall levels of sexism in a culture are high, and (d) national averages on BS and HS predict gender inequal ity across nations. These results challenge prevailing notions of prejudice as an antipathy in that BS (an affectionate, patronizing ideology) reflects inequality and is a cross-culturally pervasive complement to HS

    Go with the Flow, but Keep it Stable? The Role of Flow Variability in the Context of Daily Flow Experiences and Daily Creative Performance

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    This study investigates the correlates of daily flow experiences at work as well as flow variability (i.e. a person's level of variability in daily flow states) on daily levels of creative performance. Drawing from broaden and build theory, we hypothesised that higher levels of daily flow would be positively related to higher levels of daily creative performance. Extending research on within-person variability of flow experiences, we introduced the concept of flow variability; in particular, we hypothesised that flow variability would be negatively related to a person's creative performance at the day-level. In contrast, based on the notion of heightened reactivity in the context of intra-individual variability, we predicted that the relationship between daily flow and daily creative performance would be stronger among persons with high flow variability. We collected diary data from 44 full-time employees, who provided information on a total of 201 days. Results of multilevel analyses confirmed our predictions. Our study highlights the benefits of examining the different correlates of flow variability across levels, thus revealing an intricate web of cross-level linkages between daily flow states, flow variability, and daily creative performance at work
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