Cervantes cautivo en Sarajevo: lectura cervantina de El sitio de los sitios de Juan Goytisolo

This article proposes a comparison between the novel State of Siege (1995a) by Juan Goytisolo (English edition: 2008), with the Cervantine thought, fiction and metafiction of Jorge Luis Borges, on one side, and, on the other, with Three Trapped Tigers (1967), the innovative novel by Guillermo Cabrera Infante (English edition: 1971), and with the accurate analysis that Goytisolo made of his narrative mechanisms, relating them to the foundational novel by Cervantes (Don Quixote).Este artículo plantea una comparación entre la novela El sitio de los sitios (1995a), de Juan Goytisolo (edición inglesa: 2008), con el pensamiento cervantino y la ficción y metaficción cervantinas de Jorge Luis Borges, de un lado, y, del otro, con Tres Tristes Tigres (1967), la innovadora novela de Guillermo Cabrera Infante (edición inglesa: 1971), y con el certero análisis que Goytisolo hizo de sus mecanismos narrativos, relacionándolos con la novela fundacional de Cervantes (el Quijote)

El eros joyciano de Julián Ríos

Julián Ríos's literature is the most creative and ingenious expression of the Joycean Eros in Spanish literature. The Joycean Eros is defined, in general lines, by its relationship with human language and the languages ​​of the world, in all its promiscuous plurality, as well as by its verbal staging of the realities and misunderstandings of sex and the equivocal comedy of the genres. From Larva: A Midsummer Night's Babel (1983) to Puente de Alma (2009), Ríos' narrative assumes that verbal and carnal heritage of Joyce, appropriates it without cultural complexes, incorporates it fully into his vast literary project, without losing an apex of uniqueness and originality, thus making one of the great postmodern contributions to a literature like that of Spain so devoid of those aesthetic, intellectual and cultural qualities.La literatura de Julián Ríos es la más creativa e ingeniosa expresion del Eros joyciano en la literatura española. El Eros joyciano se define, en líneas generales, por su relación con el lenguaje humano y las lenguas del mundo, en toda su promiscua pluralidad, además de por su escenificación verbal de las realidades y los malentendidos del sexo y la comedia equívoca de los géneros. Desde Larva. Babel de una noche de San Juan (1983) hasta Puente de Alma (2009), la narrativa de Ríos asume esa herencia verbal y carnal de Joyce, se la apropia sin complejos culturales, la incorpora íntegra a su vasto proyecto literario, sin perder un ápice de singularidad y originalidad, realizando así una de las grandes contribuciones posmodernas a una literatura como la española tan desprovista de esas cualidades estéticas, intelectuales y culturales

Taxonomías transatlánticas: lo hipertextual y lo mediático en la narrativa en español del siglo XXI (fragmento)

"Katherine Hayles articula con gran perspicacia cuál es la importancia de la literatura en esta cultura mediática, sobre todo a partir de sus cualidades artísticas de la relación privilegiada de la narrativa con la subjetividad: “Amongthearts, literatura is privileged because it registers media´s effect both psychologically and heuristically” (2008: 89)...

Versiones del Quijote

Translating the classics and the agency of the translatorVersiones del Quijot

Lithography parametric yield estimation model to predict layout pattern distortions with a reduced set of lithography simulations

A lithography parametric yield estimation model is presented to evaluate the lithography distortion in a printed layout due to lithography hotspots. The aim of the proposed yield model is to provide a new metric that enables the possibility to objectively compare the lithography quality of different layout design implementations. Moreover, we propose a pattern construct classifier to reduce the set of lithography simulations necessary to estimate the litho degradation. The application of the yield model is demonstrated for different layout configurations showing that a certain degree of layout regularity improves the parametric yield and increases the number of good dies per wafer. (C) 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)Peer ReviewedPostprint (author’s final draft

Plasma homocysteine and vitamin B12 serum levels, red blood cell folate concentrations, C677T methylenetetrahydrofolate reductase gene mutation and risk of recurrent miscarriage: a case-control study in Spain.

Background: Hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) gene mutation have been postulated as a possible cause of recurrent miscarriage (RM). There is a wide variation in the prevalence of MTHFR polymorphisms and homocysteine (Hcy) plasma levels among populations around the world. The present study was undertaken to investigate the possible association between hyperhomocysteinemia and its causative genetic or acquired factors and RM in Catalonia, a Mediterranean region in Spain. Methods: Sixty consecutive patients with ≥ 3 unexplained RM and 30 healthy control women having at least one child but no previous miscarriage were included. Plasma Hcy levels, MTHFR gene mutation, red blood cell (RBC) folate and vitamin B12 serum levels were measured in all subjects. Results: No significant differences were observed neither in plasma Hcy levels, RBC folate and vitamin B12 serum levels nor in the prevalence of homozygous and heterozygous MTHFR gene mutation between the two groups studied. Conclusions: In the present study RM is not associated with hyperhomocysteinemia, and/or the MTHFR gene mutation

Complejidad versus simplicidad en prótesis total removible

En el presente trabajo valoramos los resultados a distancia (dos años) del método de elaboración de la Prótesis Total Removible, mediante la utilización de parámetros clínicos, con el fin de simplificar el proceso de elaboración de la Prótesis Total

AAV-mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice

Senescence represents a stage in life associated with elevated incidence of morbidity and increased risk of mortality due to the accumulation of molecular alterations and tissue dysfunction, promoting a decrease in the organism's protective systems. Thus, aging presents molecular and biological hallmarks, which include chronic inflammation, epigenetic alterations, neuronal dysfunction, and worsening of physical status. In this context, we explored the AAV9-mediated expression of the two main isoforms of the aging-protective factor Klotho (KL) as a strategy to prevent these general age-related features using the senescence-accelerated mouse prone 8 (SAMP8) model. Both secreted and transmembrane KL isoforms improved cognitive performance, physical state parameters, and different molecular variables associated with aging. Epigenetic landscape was recovered for the analyzed global markers DNA methylation (5-mC), hydroxymethylation (5-hmC), and restoration occurred in the acetylation levels of H3 and H4. Gene expression of pro- and anti-inflammatory mediators in central nervous system such as TNF-α and IL-10, respectively, had improved levels, which were comparable to the senescence-accelerated-mouse resistant 1 (SAMR1) healthy control. Additionally, this improvement in neuroinflammation was supported by changes in the histological markers Iba1, GFAP, and SA β-gal. Furthermore, bone tissue structural variables, especially altered during senescence, recovered in SAMP8 mice to SAMR1 control values after treatment with both KL isoforms. This work presents evidence of the beneficial pleiotropic role of Klotho as an anti-aging therapy as well as new specific functions of the KL isoforms for the epigenetic regulation and aged bone structure alteration in an aging mouse model

La calidad de vida según la vivencia de los mayores dependientes y sus cuidadores

La calidad de vida es difícil de definir y operativizar al ser un concepto muy amplio, complejo y pluridimensional. El objetivo fue comparar las definiciones, las percepciones y las dimensiones relacionadas con la calidad de vida proporcionadas por las personasmayores dependientes y cuidadores. ..

El aprendizaje de la teoría jurídica del delito a través del sistema de casos

El documento recoge la memoria del Proyecto de Innovación "El aprendizaje de la teoría jurídica del delito a través del sistema de casos" (PI nº 151). El método del caso es una de las técnicas que favorece el aprendizaje por descubrimiento. Este tipo de aprendizaje anima al alumno a hacer preguntas en el aula y formular sus propias respuestas, así como a deducir principios de ejemplos prácticos o experiencias