Design de unidades funcionais: plataforma para o desenvolvimento novos produtos universidade-indústria

Doutoramento em DesignEste trabalho de investigação teve como principais objetivos, por um lado, procurar as relações existentes entre a Instituição Ensino Superior de Design (IES-D) e as empresas, por outro, configurar um modelo que permitisse criar uma plataforma de inovação para o desenvolvimento de novos produtos na IES-D num contexto globalizado. Nos últimos anos, o setor “ensino superior” na Europa e em várias partes do mundo passou por grandes mudanças, o que acentuou o ambiente competitivo entre as IES, incluindo as de Design. Neste âmbito, procurou-se demonstrar o novo posicionamento estratégico da IES-D perante o mercado, e quais as ações a desenvolver que possibilitam alcançar uma vantagem competitiva sustentável. Primeiro, considerou-se fundamental identificar a importância do design perante o ensino, a situação mundial e a mudança da cultura económica. Depois, assinalaram-se as iniciativas de promoção do design e as políticas de inovação europeias. E por fim, reuniram-se os aspetos que obrigam as IES-D a assumir novos papéis de interação com o mercado. Por análise comparativa internacional procedeu-se à seleção de uma amostra de dezoito (18) IES-D – dez europeias, quatro norte americanas e quatro asiáticas. Instituições de ensino com tipologias diversas e pertencentes a distintos contextos socioeconómicos. A caracterização da amostra através de análise estrutural permitiu identificar aspetos comuns às IES-D – ações estratégicas que servem para promover a inovação. Para explicitar a interação do sistema formado por esses elementos comuns, configurou-se um modelo concetual – Hexágono da Inovação (HI). O modelo, enquanto instrumento de análise, permite criar um padrão da inovação da IES-D e posicioná-la perante o setor - ensino superior de design. Foi também realizado um ensaio da aplicabilidade do modelo concetual HI na ESAD.cr/IPL. Através da implementação da plataforma de inovação - ESAD Design Studio - Centro de Estudos e Investigação em Design (EDS/CEID), foram ensaiadas as ações necessárias para promover o design estratégico e o design de inovação.Based on the understanding of the relationships that exist between companies and the Higher Education Institution suffering graduated studies and researching Design (HEI-D), this research sets up a model for creating a sustainable innovation platform for the development of new products in HEI-D in the contemporary globalized context. In recent years, the "higher education" area in Europe and in many parts of the world went through major changes, which emphasized the competitive environment between the HEI, including Design. In this context, we sought to demonstrate the new strategic positioning of HEI-D before the market, and which actions to develop that make it possible to achieve a sustainable competitive advantage. We considered essential to identify different practices for the design teaching, the world situation and the economic and cultural changes, and most relevant European initiatives for the promotion of a design culture and innovation policies. And finally, there were the aspects requiring the HEI-D to assume new roles of interaction with the market. For international comparative analysis proceeded to the selection of a sample of eighteen (18) IES-D – ten European, four from the United States and four Asian. Are institutions with diverse typologies and belonging to different socio-economic contexts. The characterization of the sample through structural analysis has identified common aspects HEIs-D - strategic actions that serve to promote innovation. To clarify the interaction of the system formed by these common elements, we set up a concetual model – Hexagon Innovation (HI). This model, as an instrument of analysis that allowed to create the pattern of innovation of the HEI-D on the higher education area. It was also performed a test of applicability of concetual model HI at ESAD.cr/IPL. We developed the platform of innovation - ESAD Design Studio - Research Design Centre (EDS/RDC), to test the actions needed to promote a sustainable innovation platform for the development of new products in HEI-D

Interacção universidade-empresa : o portal Alumni como instrumento socialmente responsável e de design colaborativo

Comunicação apresentada no XI Seminário Luso-Espanhol de Gestão Empresarial, que decorreu na Universidade do Algarve em Faro, em 2009.Novas preocupações sociais, económicas e ambientais têm originado novas condutas por parte das organizações e das instituições, numa perspectiva de alcançar objectivos sustentáveis a médio e longo prazo. Assim, as entidades referidas e em particular, as instituições de ensino, têm procurado desenvolver um conjunto de práticas e ferramentas que lhes permitam interagir com todas as entidades com as quais se relacionam, adoptando assim uma postura e um comportamento coerente e transparente, com objectivos de criação de valor, enquadrando-se estas práticas na temática da Responsabilidade Social. Dentro das várias práticas de Responsabilidade Social adoptadas pelas instituições indicadas, incluem-se algumas visando os Stakeholders externos mas outrora internos, nomeadamente os seus antigos alunos, ou seja, através da criação de uma ferramenta electrónica, denominada Portal Alumni. Neste documento, pretende-se efectuar uma análise sobre a potencialidade do Portal Alumni enquanto instrumento de Design Colaborativo e de Responsabilidade Social gerador do relacionamento entre as instituições de ensino superior e os seus antigos alunos, obtendo-se assim sinergias inter-relacionais benéficas a nível da empregabilidade dos alunos, da relação com as empresas, bem como a nível do branding da instituição educativa em causa

Infectious risk of elderly patients on peritoneal dialysis: Experience of a portuguese center

Background: The goal of this study was to compare the risk of peritoneal dialysis‑related infections in younger and older patients and to identify risk factors for infection in elderly patients. Methods: We performed a longitudinal retrospective study on a population of Portuguese peritoneal dialysis patients treated at the same center between January 2005 and December 2015. Clinical and laboratory data were collected from medical reports. Two groups of patients were compared: non elderly (< 65 years) and elderly (≥ 65 years). Results: Among 100 patients, there were 73 non elderly (median age 52 years) and 27 elderly (median age 74 years). Elderly patients were not associated with higher PD‑infection rates or with less time to PD‑related infections. Cerebrovascular disease was the only significant adverse predictor of peritonitis in elderly (crude HR 3.8; 95% CI 1.10 to 13.34; P = 0.035) and those with higher levels of serum albumin were less likely to develop peritonitis (crude HR 0.47 per each g/dl of increase; 95% CI 0.24 to 0.89; P = 0.023). Conclusions: In our study, elderly patients did not present a greater risk for peritonitis or catheter‑related infections.info:eu-repo/semantics/publishedVersio

Antibiotic resistance in wastewater: Occurrence and fate ofEnterobacteriaceaeproducers of Class A and Class C β-lactamases

Antibiotics have been intensively used over the last decades in human and animal therapy and livestock, resulting in serious environmental and public health problems, namely due to the antibiotic residues concentration in wastewaters and to the development of antibiotic-resistant bacteria. This study aimed to access the contribution of some anthropological activities, namely urban household, hospital and a wastewater treatment plant, to the spread of antibiotic resistances in the treated wastewater released into the Mondego River, Coimbra, Portugal. Six sampling sites were selected in the wastewater network and in the river. The ampicillin-resistant Enterobacteriaceae of the water samples were enumerated, isolated and phenotypically characterized in relation to their resistance profile to 13 antibiotics. Some isolates were identified into species level and investigated for the presence of class A and class C -lactamases. Results revealed high frequency of resistance to the -lactam group, cefoxitin (53.5%), amoxicillin/clavulanic acid combination (43.5%), cefotaxime (22.7%), aztreonam (21.3) cefpirome (19.2%), ceftazidime (16.2%) and to the non--lactam group, trimethoprim/sulfamethoxazol (21.1%), tetracycline (18.2%), followed by ciprofloxacin (14.1%). The hospital effluent showed the higher rates of resistance to all antibiotic, except two (chloramphenicol and gentamicin). Similarly, higher resistance rates were detected in the wastewater treatment plant (WWTP) effluent compared with the untreated affluent. Regarding the multidrug resistance, the highest incidence was recorded in the hospital sewage and the lowest in the urban waste. The majority of the isolates altogether are potentially extended-spectrum -lactamases positive (ESBL(+)) (51.9%), followed by AmpC(+) (44.4%) and ESBL(+)/AmpC(+) (35.2%). The most prevalent genes among the potential ESBL producers were blaOXA (33.3%), blaTEM (24.1%) and blaCTX-M (5.6%) and among the AmpC producers were blaEBC (38.9%), blaFOX (1.9%) and blaCIT (1.9%). In conclusion, the hospital and the WWTP activities revealed to have the highest contribution to the spread of multidrug resistant bacteria in the study area. Such data is important for future management of the environmental and public health risk of these contaminants. This is the first embracing study in the water network of Coimbra region on the dissemination of antibiotic resistance determinants. Moreover, it is also the first report with the simultaneous detection of multiresistant bacteria producers of AmpC and ESBLs -lactamases in aquatic systems in Portugal.info:eu-repo/semantics/publishedVersio

Rede Alumni : uma estratégia responsável ao serviço do desenvolvimento do turismo local

Comunicação apresentada no VI International Tourism Congress, ESTM, Peniche, 2013.Organizations including higher education institutions need to enhance the relationships with their stakeholders, especially with their alumni, in order to promote a set of long term mutual competitive advantages. In this way, organizational sustainability is gaining new ground and plays a fundamental role as a way of attaining a broad goal in terms of sustainable development. Higher education institutions should develop relationship and transparency strategies of corporate actions in order to create trust and also to leverage synergies by using alumni networks. This can be achieved through Information and Communication Technologies (ICT), especially the web, and the most recent and globalized platforms like Facebook and Linkedin as privileged channels for communicating with alumni. In addition, the development of actions that try to promote an approach and the engagement of alumni among different initiatives not only inside the institution, but also in terms of local and/or regional context, could create added value and contribute to local tourism development. The present study aims to analyze the development of the network of a higher education institution, namely, the IPLeiri@lumni Network, assessing the platform design, the measures taken by the institution to renew the relationship with their alumni, and the resulting advantages from the paths taken by some alumni as a way of identifying the potential added value for the development of local tourism of the region

Morphological, biological and molecular characterization of three strains of Trypanosoma cruzi Chagas, 1909 (Kinetoplastida, Trypanosomatidae) isolated from Triatoma sordida (Stal) 1859 (Hemiptera, Reduviidae) and a domestic cat

A study was conducted of the biological, morphological and molecular characters of 3 strains of Trypanosoma cruzi (SI5, SI8 and SIGR3) isolated from specimens of Triatoma sordida collected in Santo Inácio and a domestic cat. In order to carry out the study, the following parameters were evaluated: pre-patent period, parasitaemia curves, morphology of the parasites, mortality rates, histopathological lesions and molecular typing. The strains presented variable pre-patent periods, low parasitaemia and no animal mortality. The morphological study of trypomastigotes showed a predominance of intermediate-width and short-length forms, as well as low nuclear index. Epimastigotes presented a low nuclear index, intermediate-width forms in strains SI5 and SI8, and large-width forms in SIGR3. A shorter length could be noted in strains SI8 and SIGR3, whereas SI5 displayed an intermediate length. The histopathological study did not detect amastigote nests in tissues. The amplification of the divergent domain of 24Sα rRNA, HSP60 and GPI genes of strains SI5, SI8 and SIGR3 classified the 3 strains into Group II. Biological parameters made it possible to classify the strains isolated in Santo Inácio (BA) into Biodeme III, Zymodeme 1 and Group II of T. cruzi

Minas esgotada : antecedentes e impactos do desastre da Vale na Bacia do Paraopeba

-A obra oferece um panorama das questões sociais e ambientais ligadas à mineração em Minas Gerais, trazendo os sujeitos e a paisagem como protagonistas da narrativa. Ela reúne autores que assumem a responsabilidade social do fazer científico, analisando a assimetria de poder, o jogo político, os antecedentes e consequências ambientais do rompimento da barragem da Vale S.A no Complexo Paraopeba II, em 2019. Os textos transitam entre esforços teórico-reflexivos e aproximações empíricas; nascem do histórico de engajamento dos pesquisadores com a problemática da mineração e questões socioambientais, adornado por sucessivos trabalhos de campo e contatos com a população atingida

Influenza severe cases in hospitals, between 2014 and 2016 in Portugal

Rede Portuguesa de Laboratórios para o Diagnóstico da GripeBackground: Since 2009, the Portuguese Laboratory Network (PLNID) for Influenza Diagnosis has integrated 15 Laboratories in mainland and Atlantic Islands of Azores and Madeira. This PLNID added an important contribute to the National Influenza Surveillance Program regarding severe and hospitalized influenza cases. The present study aims to describe influenza viruses detected in influenza like illness (ILI) cases: outpatients (Outp), hospitalized (Hosp), and intensive care units (ICU), between 2014 and 2016. Methods: The PLNID performs influenza virus diagnosis by biomolecular methodologies. Weekly reports to the National Influenza Reference Laboratory ILI cases tested for influenza. Reports include data on detecting viruses, hospital assistance, antiviral therapeutics, and information on death outcome. Were reported during two winter seasons 8059 ILI cases,being 3560 cases in 2014/15 (1024 in Outp, 1750 Hosp, and 606 in ICU) and 4499 cases in 2015/2016 (1933 in Outp, 1826 Hosp, and 740 in ICU). Results: The higher percentage of influenza positive cases were detected in Outp in both seasons, 18% during 2014/15 and 20% in 2015/16. In 2014/15,influenza cases were more frequent in individuals older than 65 years old and these required more hospitalizations,even in ICU. In 2015/16,the influenza cases were mainly detected in individuals between 15-64 years old. A higher proportion of influenza positive cases with hospitalization in ICU were observed in adults between 45-64 years old.During the study period,the predominant circulating influenza viruses were different in the two seasons: influenza B and A(H3) co-circulated in 2014/15,and influenza A(H1)pdm09 was predominant during 2015/16. Even when influenza A is notthe dominant virus, A(H3) and A(H1)pdm09 subtypes correlate with higher detection rate in hospitalized cases (Hosp and UCI), with higher frequencies in adults older than 45. Influenza B,detected in higher proportion in outpatients, was frequently relatedwith influenza cases in younger age groups: 0-4 and 5-14 years old. Conclusions: This study highlights the correlation of theinfluenza virus type/subtype that circulates in each season with the possible need for hospitalization and intensive care in special groups of the population. Circulation of influenza A subtypes can cause more frequentdisease in individuals older than 45, with need of hospitalization including intensive care. On the other hand, influenza B is more frequently associated with less severe cases and with infection in children and younger adults. Influenza B circulation might predict lower number of hospitalizations.The identification of influenza type in circulation,byPLNID ineach season, could guide action planning measures in population health care.info:eu-repo/semantics/publishedVersio