Draft Genome Sequences of Five Enterococcus Species Isolated from the Gut of Patients with Suspected Clostridium difficile Infection

Indexación: Scopus.We present draft genome sequences of five Enterococcus species from patients suspected of Clostridium difficile infection. Genome completeness was confirmed by presence of bacterial orthologs (97%). Gene searches using Hidden-Markov models revealed that the isolates harbor between seven and 11 genes involved in antibiotic resistance to tetracyclines, beta-lactams, and vancomycin.http://genomea.asm.org/content/5/20/e00379-17.ful

Searching for tidal tails around ω\omega Centauri using RR Lyrae Stars

We present a survey for RR Lyrae stars in an area of 50 deg$^2$ around the globular cluster $\omega$ Centauri, aimed to detect debris material from the alleged progenitor galaxy of the cluster. We detected 48 RR Lyrae stars of which only 11 have been previously reported. Ten among the eleven previously known stars were found inside the tidal radius of the cluster. The rest were located outside the tidal radius up to distances of $\sim 6$ degrees from the center of the cluster. Several of those stars are located at distances similar to that of $\omega$ Centauri. We investigated the probability that those stars may have been stripped off the cluster by studying their properties (mean periods), calculating the expected halo/thick disk population of RR Lyrae stars in this part of the sky, analyzing the radial velocity of a sub-sample of the RR Lyrae stars, and finally, studying the probable orbits of this sub-sample around the Galaxy. None of these investigations support the scenario that there is significant tidal debris around $\omega$ Centauri, confirming previous studies in the region. It is puzzling that tidal debris have been found elsewhere but not near the cluster itself.Comment: 11 pages, 11 figures, Accepte

Close encounters involving RAVE stars beyond the 47 Tucanae tidal radius

The most accurate 6D phase-space information from the Radial Velocity Experiment (RAVE) was used to integrate the orbits of 105 stars around the galactic globular cluster 47 Tucanae, to look for close encounters between them in the past, with a minimum distance approach less than the cluster tidal radius. The stars are currently over the distance range 3.0 kpc $<$ d $<$ 5.5 kpc. Using the uncertainties in the current position and velocity vector for both, star and cluster, 105 pairs of star-cluster orbits were generated in a Monte Carlo numerical scheme, integrated over 2 Gyr and considering an axisymmetric and non-axisymmetric Milky-Way-like Galactic potential, respectively. In this scheme, we identified 20 potential cluster members that had close encounters with the globular cluster 47 Tucanae, all of which have a relative velocity distribution (V$_{rel}$) less than 200 km s$^{-1}$ at the minimum distance approach. Among these potential members, 9 had close encounters with the cluster with velocities less than the escape velocity of 47 Tucanae, therefore a scenario of tidal stripping seems likely. These stars have been classified with a 93\% confidence level, leading to the identification of extratidal cluster stars. For the other 11 stars, V$_{rel}$ exceeds the escape velocity of the cluster, therefore they were likely ejected or are unassociated interlopers.Comment: 10 pages, 6 figures, 2 table, Accepted for publication in MNRA

Possible ring material around centaur (2060) Chiron

We propose that several short duration events observed in past stellar occultations by Chiron were produced by rings material. From a reanalysis of the stellar occultation data in the literature we determined two possible orientations of the pole of Chiron's rings, with ecliptic coordinates l=(352+/-10) deg, b=(37+/-10) deg or l=(144+/-10) deg, b=(24+/-10) deg . The mean radius of the rings is (324 +/- 10) km. One can use the rotational lightcurve amplitude of Chiron at different epochs to distinguish between the two solutions for the pole. Both imply lower lightcurve amplitude in 2013 than in 1988, when the rotational lightcurve was first determined. We derived Chiron's rotational lightcurve in 2013 from observations at the 1.23-m CAHA telescope and indeed its amplitude is smaller than in 1988. We also present a rotational lightcurve in 2000 from images taken at CASLEO 2.15-m telescope that is consistent with our predictions. Out of the two poles the l=(144+/-10) deg, b=(24+/-10) deg solution provides a better match to a compilation of rotational lightcurve amplitudes from the literature and those presented here. We also show that using this preferred pole, Chiron's long term brightness variations are compatible with a simple model that incorporates the changing brightness of the rings as the tilt angle with respect to the Earth changes with time. Also, the variability of the water ice band in Chiron's spectra in the literature can be explained to a large degree by an icy ring system whose tilt angle changes with time and whose composition includes water ice, analogously to the case of Chariklo. We present several possible formation scenarios for the rings from qualitative points of view and speculate on the reasons why rings might be common in centaurs. We speculate on whether the known bimodal color distribution of centaurs could be due to presence of rings and lack of them

Discovery of a Metal-Poor Field Giant with a Globular Cluster Second-Generation Abundance Pattern

We report on the detection, from observations obtained with the Apache Point Observatory Galactic Evolution Experiment spectroscopic survey, of a metal-poor ([Fe/H] = −1.3 dex) field giant star with an extreme Mg–Al abundance ratio ([Mg/Fe] = −0.31 dex; [Al/Fe] = 1.49 dex). Such low Mg/Al ratios are seen only among the second-generation population of globular clusters (GCs) and are not present among Galactic disk field stars. The light-element abundances of this star, 2M16011638-1201525, suggest that it could have been born in a GC. We explore several origin scenarios, studying the orbit of the star in particular to check the probability of its being kinematically related to known GCs. We performed simple orbital integrations assuming the estimated distance of 2M16011638-1201525 and the available six-dimensional phase-space coordinates of 63 GCs, looking for close encounters in the past with a minimum distance approach within the tidal radius of each cluster. We found a very low probability that 2M16011638-1201525 was ejected from most GCs; however, we note that the best progenitor candidate to host this star is GC ω Centauri (NGC 5139). Our dynamical investigation demonstrates that 2M16011638-1201525 reaches a distance $| {Z}_{\max }| \lt 3\,\mathrm{kpc}$ from the Galactic plane and minimum and maximum approaches to the Galactic center of R min < 0.62 kpc and R max < 7.26 kpc in an eccentric (e ~ 0.53) and retrograde orbit. Since the extreme chemical anomaly of 2M16011638-1201525 has also been observed in halo field stars, this object could also be considered a halo contaminant, likely to have been ejected into the Milky Way disk from the halo. We conclude that 2M16011638-20152 is also kinematically consistent with the disk but chemically consistent with halo field stars

Comorbidities in Chilean patients with psoriasis: a Global Healthcare Study on Psoriasis

Background: Psoriasis is a chronic inflammatory skin disease associated with several important medical comorbidities. There are scant data available on the comorbidities of patients with psoriasis in South America. Aim: To examine the comorbidity profile of adult patients with psoriasis in Chile and its association with severity of psoriasis. Methods: This was a multicentre, cross-sectional study involving 16 hospitals and clinics in Chile, which used a 48-item questionnaire to study clinician- and patient-reported outcomes and comorbidities. Inferential analyses were performed by psoriasis severity, using Fisher exact test, Student t-test and multivariable logistic regression. Results: In total, 598 adult patients with psoriasis were included (51.1% male; mean age 49.2 ± 15.1 years); 48.5% mild and 51.4% moderate to severe; Psoriasis Area and Severity Index 11.6 ± 11.5; body surface area 14.7 ± 18.2%. Plaque psoriasis was the most common phenotype (90.2%), followed by guttate (13.4%). Psoriatic arthritis occurred in 27.3% of patients. Comorbidities were reported in 60.2% of all patients with psoriasis. Frequent concomitant diseases were obesity (25.3%), hypertension (24.3%), Type 2 diabetes mellitus (T2DM) (18.7%), dyslipidaemia (17.4%), metabolic syndrome (16.7%) and depression (14.4%). After adjustment, significant associations were found between moderate to severe psoriasis and obesity, T2DM and nonalcoholic fatty liver disease (NAFLD) compared with mild psoriasis. Conclusions: We report a large study of comorbidities, including depression, dyslipidaemia, T2DM and NAFLD, in people with psoriasis in Chile. The prevalence of comorbidities with psoriasis in Chile appears similar to that found in Western countries, and emphasizes the importance of assessing patients with psoriasis for risk factors for and presence of, comorbid disease in a multidisciplinary setting

V01 345. Implante de prótesis aórtica transcatéter por vía transaórtica: una alternativa de abordaje a las vías convencionales

Objetivosel implante de prótesis valvulares aórticas por vía transcatéter es una opción terapéutica reconocida en pacientes de alto riesgo quirúrgico. Nuestro objetivo es mostrar una vía de abordaje alternativa para su implante en algunos pacientes no candidatos para las vías usuales de acceso vascular periférico (femoral/subclavia) o transapical.Material y métodospresentamos el caso de un varón de 74 años con estenosis aórtica grave, CF IV y fracción de eyección del ventrículo izquierdo (FEVI) gravemente deprimida. Antecedentes de neoplasia de colon, diabetes mellitus tipo 2, enfermedad vascular periférica grave, cardiopatía isquémica crónica con revascularización percutánea mediante stents convencionales y neumonectomía derecha por carcinoma de pulmón. EuroSCORE logístico: 42,57%. Ecocardiograma: válvula aórtica trivalva (gradiente máximo 76, medio 51mmHg, área: 0,6cm2;, anillo: 24mm). Angiotomografía computarizada (angio-TC): grave ateromatosis ilíaca bilateral, desplazamiento importante del ápex cardíaco hacia la línea media y de la aorta ascendente hacia el hemitórax derecho. Cateterismo: ateromatosis grave de subclavia izquierda y estenosis grave de subclavia derecha, no reestenosis intra-stents.Se somete a implante de prótesis aórtica Core-Valve autoexpandible número 29 vía transaórtica (aorta ascendente) bajo visión directa a través de minitoracotomía anterior derecha por segundo espacio intercostal.Resultadosel paciente es extubado en 6h. Ecocardiograma de control: prótesis con apertura conservada e insuficiencia aórtica ligera-moderada. Ritmo sinusal estable.Conclusionesaunque la vía transaórtica mediante cirugía mínimamente invasiva está aún poco utilizada, en pacientes con alto riesgo para cirugía convencional puede ser una opción factible y segura para el implante de prótesis transcatéter en las que no sea posible el abordaje habitual

Submarine canyons and related features in the Alboran Sea: continental margins and major isolated reliefs

The analysis of a data set of multibeam bathymetry plus high resolution seismic and parametric profiles allow us to characterize the geomorphologic units on the Alboran Sea-floor as well as the evolution of morpho-sedimentary systems along the Pliocene and Quaternary, later than the main erosive Messinian event. Since the opening of the Gibraltar Straits, the sedimentary evolution of this basin has been controlled by the interchange of water masses between the Atlantic Ocean and the Mediterranean Sea. Basin physiography is also a consequence of the Pliocene-Quaternary compression which has progressively uplifted the sourrounding reliefs and deforms the interior and the margins of the basin. On this scenario, several submarine canyons and gullies have been developed in this basin which traverse especially the northern margin and the flanks of the Northern Alboran Ridge, without affecting the African margins. This fact must be related to the action of bottom contour currents which constitute the main morpho-sedimentary process. The influence of water masses distributed the sedimentary input carried by rivers and coming from the erosion of surrounding ranges. In the southern margin of this basin this influence is stronger and inhibits the development of transversal submarine canyons