PT-symmetry broken by point-group symmetry

We discuss a PT-symmetric Hamiltonian with complex eigenvalues. It is based on the dimensionless Schr\"{o}dinger equation for a particle in a square box with the PT-symmetric potential $V(x,y)=iaxy$. Perturbation theory clearly shows that some of the eigenvalues are complex for sufficiently small values of $|a|$. Point-group symmetry proves useful to guess if some of the eigenvalues may already be complex for all values of the coupling constant. We confirm those conclusions by means of an accurate numerical calculation based on the diagonalization method. On the other hand, the Schr\"odinger equation with the potential $V(x,y)=iaxy^{2}$ exhibits real eigenvalues for sufficiently small values of $|a|$. Point group symmetry suggests that PT-symmetry may be broken in the former case and unbroken in the latter one

Phenomenology Tools on Cloud Infrastructures using OpenStack

We present a new environment for computations in particle physics phenomenology employing recent developments in cloud computing. On this environment users can create and manage "virtual" machines on which the phenomenology codes/tools can be deployed easily in an automated way. We analyze the performance of this environment based on "virtual" machines versus the utilization of "real" physical hardware. In this way we provide a qualitative result for the influence of the host operating system on the performance of a representative set of applications for phenomenology calculations.Comment: 25 pages, 12 figures; information on memory usage included, as well as minor modifications. Version to appear in EPJ

Asymptotic behavior and numerical approximation of a double-suspended bridge system

This paper is devoted to introduce and analyze a new non linear problem describing the vibrations of a double suspended bridge system. The road bed is modeled as a double beam of Woinowsky-Krieger type and the two cables, each connected to a single beam by a distributed system of elastic springs, are modeled as one-sided elastic strings. We achieve the existence and uniqueness of solutions by using the semigroup theory and the exponential decay property is also proved. Then, the model is numerically analyzed, through a variational formulation, by using the finite element method and a first-order time integration scheme. A priori error estimates are obtained and the linear convergence is derived under some suitable additional regularity conditions. Finally, some numerical experiments are performed to verify the behavior of the numerical method.Universidade Vigo/CISU

How are risk ratios reported in orthopaedic surgery journals? A descriptive study of formats used to report absolute risks

The numerical format in which risks are communicated can affect risk comprehension and perceptions of medical professionals. We investigated what numerical formats are used to report absolute risks in empirical articles, estimated the frequency of biasing formats and rated the quality of figures used to display the risks. Descriptive study of reporting practices. We randomly sampled articles published in seven leading orthopaedic surgery journals during a period of 13 years. From these, we selected articles that reported group comparisons on a binary outcome (eg, revision rates in two groups) and recorded the numerical format used to communicate the absolute risks in the results section. The quality of figures was assessed according to published guidelines for transparent visual aids design. Prevalence of information formats and quality of figures. The final sample consisted of 507 articles, of which 14% reported level 1 evidence, 13% level 2 and 73% level 3 or lower. The majority of articles compared groups of different sizes (90%), reported both raw numbers and percentages (64%) and did not report the group sizes alongside (50%). Fifteen per cent of articles used two formats identified as biasing: only raw numbers (8%, '90 patients vs 100 patients') or raw numbers reported alongside different group sizes (7%, '90 out of 340 patients vs 100 out of 490 patients'). The prevalence of these formats decreased in more recent publications. Figures (n=79) had on average two faults that could distort comprehension, and the majority were rated as biasing. Authors use a variety of formats to report absolute risks in scientific articles and are likely not aware of how some formats and graph design features can distort comprehension. Biases can be reduced if journals adopt guidelines for transparent risk communication but more research is needed into the effects of different formats

Thermogalvanic corrosion of Alloy 31 in different heavy brine LiBr solutions

Thermogalvanic corrosion generated between two electrodes of Alloy 31, a highly-alloyed austenitic stainless steel (UNS N08031), has been investigated imposing different temperature gradients in three deaerated LiBr solutions, under open circuit conditions by using a zero-resistance ammeter (ZRA). Besides EIS spectra were acquired in order to explain the obtained results. On the whole, cold Alloy 31 electrodes were anodic to hot Alloy 31 electrodes, since an increase in temperature favoured the cathodic behaviour of the hot electrode. Thermogalvanic corrosion of Alloy 31 in the LiBr solutions studied was not severe, although it negatively affects the corrosion resistance of the cold anode. The protective properties of the passive film formed on the anode surface were found to improve with thermogalvanic coupling time

PACDIN statement of methods

This is an Accepted Manuscript of an article published by Taylor & Francis in Vehicle System Dynamics on 2014 available online: https://doi.org/10.1080/00423114.2014.963126[EN] PAntograph-Catenary Dynamic Interaction (PACDIN) is a code developed by the vehicle technology research centre (CITV) of the Universitat Politecnica de Valencia in collaboration with the railway company Talgo S.L. The model of the catenary is a finite element model using absolute nodal coordinates. It is based on a general formulation that can be applied for analysing a wide range of catenary configurations, including stitch wire, transitions or non-straight path tracks. The formulation is fully non-linear and includes large deformations, dropper slackening and contact interaction. The model is linearised when deformations are small, as in the case of the benchmark dynamic analysis. The results of the PACDIN code show a good agreement with the average results of other benchmark codes.The authors wish to thank Generatitat Valenciana for the financial support received in the framework of the PROMETEO 2012/023 Programme.Tur Valiente, M.; Baeza González, LM.; Fuenmayor Fernández, F.; Garcia, E. (2014). PACDIN statement of methods. Vehicle System Dynamics. 53(3):402-411. https://doi.org/10.1080/00423114.2014.963126S402411533Shabana, A. A. (1998). Nonlinear Dynamics, 16(3), 293-306. doi:10.1023/a:1008072517368BERZERI, M., & SHABANA, A. A. (2000). DEVELOPMENT OF SIMPLE MODELS FOR THE ELASTIC FORCES IN THE ABSOLUTE NODAL CO-ORDINATE FORMULATION. Journal of Sound and Vibration, 235(4), 539-565. doi:10.1006/jsvi.1999.2935Gerstmayr, J., & Shabana, A. A. (2006). Analysis of Thin Beams and Cables Using the Absolute Nodal Co-ordinate Formulation. Nonlinear Dynamics, 45(1-2), 109-130. doi:10.1007/s11071-006-1856-1Tur, M., García, E., Baeza, L., & Fuenmayor, F. J. (2014). A 3D absolute nodal coordinate finite element model to compute the initial configuration of a railway catenary. Engineering Structures, 71, 234-243. doi:10.1016/j.engstruct.2014.04.015Collina, A., & Bruni, S. (2002). Numerical Simulation of Pantograph-Overhead Equipment Interaction. Vehicle System Dynamics, 38(4), 261-291. doi:10.1076/vesd.38.4.261.828

Effect of Temperature on Thermogalvanic Coupling of Alloy 31 in Libr Solutions Studied by Means of Imposed Potential Measurements

Corrosion resistance of Alloy 31, a highly alloyed stainless steel (UNS N08031) were studied in heavy brine LiBr solutions (400, 700 and 992 g/l) at different temperatures using electrochemical techniques. The mixed potential theory was used to evaluate thermogalvanic corrosion of Alloy 31 in the studied LiBr solutions. Potentiodynamic curves indicate that high temperatures favoured both cathodic and anodic processes, increasing passive current densities and decreasing the pitting potential. Generally, the cold electrode of the pair was the anode of the thermogalvanic cell

Repassivation of the damage generated by cavitation on UNS N08031 in a LiBr solution by means of electrochemical techniques and Confocal Laser Scanning Microscopy

The objective of this work is to study the influence of cavitation on the corrosion behaviour of Alloy 31, a highly-alloyed austenitic stainless steel (UNS N08031), in a LiBr heavy brine solution (992 g/L) at 25 °C. The presence of cavitation shifted the OCP value towards the active direction by 708 mVAg/AgCl, increased anodic current densities and passivation current density, ip, and reduced the pitting potential, Ep. Repassivation behaviour of Alloy 31 has been investigated by using potentiostatic tests at different potentials. The current density transient obtained after interrupting cavitation was used to obtain the repassivation index, n, provided by the slope of the log i(t) vs. log t representation. The value of n decreased as the applied potential was increased, reaching values near zero for potentials close to the pitting potential. The damage generated during the potentiostatic tests has been quantified by means of Confocal Laser Scanning Microscopy

Cell death in hepatocellular carcinoma: Pathogenesis and therapeutic opportunities

Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer and the third leading cause of cancer death worldwide. Closely associated with liver inflammation and fibrosis, hepatocyte cell death is a common trigger for acute and chronic liver disease arising from different etiologies, including viral hepatitis, alcohol abuse, and fatty liver. In this review, we discuss the con-tribution of different types of cell death, including apoptosis, necroptosis, pyroptosis, or autophagy, to the progression of liver disease and the development of HCC. Interestingly, inflammasomes have recently emerged as pivotal innate sensors with a highly pathogenic role in various liver diseases. In this regard, an increased inflammatory response would act as a key element promoting a pro-oncogenic microenvironment that may result not only in tumor growth, but also in the formation of a premetastatic niche. Importantly, nonparenchymal hepatic cells, such as liver sinusoidal endothelial cells, hepatic stellate cells, and hepatic macrophages, play an important role in establishing the tumor microenvironment, stimulating tumorigenesis by paracrine communication through cytokines and/or angiocrine factors. Finally, we update the potential therapeutic options to inhibit tumorige-nesis, and we propose different mechanisms to consider in the tumor microenvironment field for HCC resolution. © 2021 by the authors. Licensee MDPI, Basel, Switzerland