2,018 research outputs found

    Marco conceptual de la ética y la responsabilidad social empresarial: un enfoque antropológico y estratégico

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    Este artículo proporciona –apoyado sobre el análisis de la literatura reciente sobre la ética empresarial y RSE– un marco conceptual original e integrador, que hace hincapié en la importancia de la fundamentación teórica de la ética basándose en una concepción antropológica adecuada y en la necesidad de establecer las políticas de RSE desde un enfoque estratégico. Ofrece una visión panorámica iluminadora acerca de la relación entre los diferentes conceptos del management que tienen implicaciones directas sobre el diseño e implantación de la ética y la RSE en las organizaciones, incluyendo tópicos como el liderazgo, la cultura empresarial, la teoría de las organizaciones y el gobierno corporativo, entre otros.This article provides, –supported on the analysis of recent literature on business ethics and CSR– an original and integrative conceptual framework that emphasizes the importance of the theoretical foundation of ethics based on an adequate anthropological model and the need to establish CSR policies from a strategic approach. Presents an illuminating overview of the relationship between different concepts of management that have direct implications on the design and implementation of ethics and CSR in organizations, including topics as leadership, corporate culture, organizational theory and corporate governance, among others

    Desarrollo de una presentación interactiva y multimedia orientada a la docencia del análisis cinemático del Movimiento Armónico Simple

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    Nowadays, computers suppose a great potential as complementary didactic tool to traditional means of education. For that reason, the advantage of this potential is considered by the work group, creating interactive and multimedia presentations oriented to facilitate teaching of different physics fields. In particular, the objective of this work is the design of a presentation oriented to teaching kinematical aspects of the simple harmonic movement. Given the dynamic nature of the subject, it is evident the adventages that suppose an animated presentation which it helps the student to understand the kinematical magnitudes. This tool will be very useful to the professor as complement of theoretical classes, and available to the students in the reinforcement of the knowledge.Es evidente el gran potencial que el ordenador supone como herramienta didáctica complementaria a los medios de enseñanza tradicionales. Es por ello que el grupo de trabajo se plantea el aprovechamiento de este potencial, creando presentaciones interactivas y multimedia orientadas a la docencia en los distintos campos de la física.En concreto, en este trabajo se plantea el diseño de una presentación orientada a la docencia de los aspectos cinemáticas del movimiento armónico simple. Dada la naturaleza dinámica del tema en cuestión, es evidente las ventajas que supone disponer de una presentación animada del mismo que ayude al alumno a entender la magnitudes cinemáticas implicadas, herramientas de gran utilidad para el profesor como complemento de sus clases teóricas, y disponible para alumnos de ayuda en el afianzamiento de los conocimientos

    Evaluation of the application of fertilizers and biostimulants in Zephyranthes lindleyana Herb (Amarylidaceae) under greenhouse conditions

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    Objective: To evaluate the effect of different doses of N, P, K fertilizers and two biostimulants, on growth parameters and vegetative development in plants of the species Z. lindleyana Herb. Design/methodology/approach: An experiment was established under greenhouse conditions under a CRD; ten treatments with five repetitions were tested, with different doses of N, P and K and two biostimulants. The experimental unit was one plant per pot. Data were analyzed with descriptive statistics, non-parametric Kruskal-Wallis tests (α=0.05). Budding, flowering, leaf height, number of leaves and seed production were measured. Results: Vegetative development was distinguished in all plants. Only six treatments showed flowering. The percentage of floral and vegetative sprouting did not show delay or advance in the physiology of the plant. In leaf height and number of leaves, different behaviors were detected in the treatments, not detected in the Kruskal-Wallis tests. The plants treated with high doses of NPK fertilization and combined with biostimulants showed inflorescences and seed production. Limitations on study/implications: Being a native plant with ornamental potential, the collection of this species is a challenge due to the lack of studies on the potential distribution of the species. Findings/conclusions: This species can be cultivated under a greenhouse and pot planting system. Floral budding, height and number of leaves is stimulated by high doses of nitrogen. The combination of NPK and biostimulants favors development/growth and seed production

    The Outcomes of Gestational Diabetes Mellitus after a Telecare Approach Are Not Inferior to Traditional Outpatient Clinic Visits

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    Objective. To evaluate the feasibility of a telemedicine system based on Internet and a short message service in pregnancy and its influence on delivery and neonatal outcomes of women with gestational diabetes mellitus (GDM). Methods. 100 women diagnosed of GDM were randomized into two parallel groups, a control group based on traditional face-to-face outpatient clinic visits and an intervention group, which was provided with a Telemedicine system for the transmission of capillary glucose data and short text messages with weekly professional feedback. 97 women completed the study (48/49, resp.). Main Outcomes Measured. The percentage of women achieving HbA1c values <5.8%, normal vaginal delivery and having a large for-gestational-age newborn were evaluated. Results. Despite a significant reduction in outpatient clinic visits in the experimental group, particularly in insulin-treated women (2.4 versus 4.6 hours per insulin-treated woman resp.; P < .001), no significant differences were found between the experimental and traditional groups regarding HbA1c levels (all women had HbA1c <5.8% during pregnancy), normal vaginal delivery (40.8% versus 54.2%, resp.; P > .05) and large-for-gestational-age newborns (6.1% versus 8.3%, resp.; P > .05). Conclusions. The system significantly reduces the need for outpatient clinic visits and achieves similar pregnancy, delivery, and newborn outcomes

    Neurological soft signs in obsessive-compulsive disorder: two empirical studies and meta-analysis

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    Neurological soft signs (NSS) have been inconsistently reported in obsessive-compulsive disorder (OCD) but may make an impact on treatment response. Method: The current study examined the presence of NSS in two independent European samples of OCD patients (combined 85 patients and 88 matched healthy controls) using a standardized instrument and conducted a meta-analysis of all published studies identified in the literature with the aim to provide a more definitive answer to the question of whether OCD patients are characterized by increased NSS. Results Both empirical studies found elevated NSS scores in patients compared with matched controls. The results of the meta-analysis, which included 15 studies (combined 498 patients and 520 controls) showed large effect sizes (Hedges' g=1.27, 95% confidence interval 0.80-1.75), indicating that OCD patients have significantly higher rates of NSS than matched controls on both sides of the body and in multiple domains (motor coordination, sensory integration and primitive reflexes). The results were robust and remained largely unchanged in our reliability analyses, which controlled for possible outliers. Meta-regression was employed to examine the role of potential variables of interest including sociodemographic variables, symptom severity, medication effects and the use of different instruments, but none of these variables was clearly associated with NSS. Conclusions: As a group, OCD patients are characterized by increased rates of NSS, compared with healthy controls. However, their origins and potential clinical importance remain to be clarified. Future directions for research are discussed

    The registry of home artificial nutrition and ambulatory of the Spanish society of parenteral and enteral nutrition: Swot analysis

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    Objetivo: Evidenciar mediante un análisis DAFO-R realizado por consenso de expertos las características más acuciantes del registro de Nutrición Artificial Domiciliaria y Ambulatoria. Material y método: Análisis DAFO-R por consenso de expertos. Se solicitó la participación de los miembros del grupo NADYA activos en los últimos 5 años bajo la premisa de estructurar el DAFO-R sobre las características del registro NADYA desde su inicio. Resultados: Han participado 18 expertos de diferentes hospitales de la geografía española. El análisis interno se inclina positivamente presentando al registro con recursos importantes. En el análisis externo no son numerosas las amenazas, hay factores de gran potencia, “la voluntariedad del registro” y la “dependencia externa de financiación”. Las oportunidades identificadas son importantes. Las recomendaciones se dirigen a la estabilización del sistema disminuyendo las amenazas como foco principal de las estrategias a desarrollar al mismo tiempo que se debe potenciar los puntos identificados en oportunidades y fortalezas. Conclusiones: El registro NADYA se muestra en el análisis con gran potencialidad de mejora. Las recomendaciones propuestas deberán estructurarse para continuar la tendencia de desarrollo y perfeccionamiento de la calidad que ha caracterizado al registro NADYA desde su inicio.Objective: To evidence by means of a SWOT-R analysis performed by an expert consensus the most worrying characteristics of the register on Home-based and Outpatient Artificial Nutrition. Material and methods: SWOT-R analysis with expert consensus. We requested the participation of the active members of the NADYA group within the last 5 years with the premise of structuring the SWOT-R based on the characteristics of the NADYA registry from its beginning. Results: 18 experts from hospitals all over Spain have participated. The internal analysis seems to be positive, presenting the registry as having important resources. The external analysis did not show a great number of threats, there are very potent factors, “the voluntariness” of the registry and the “dependence on external financing”. The opportunities identified are important. The recommendations are aimed at stabilizing the system by decreasing the threats as one of the main focus of the strategies to develop as well as promoting the items identified as opportunities and strengths. Conclusions: The analysis shows that the NADYA register shows a big potentiality for improvement. The proposed recommendations should be structured in order to stay on the track of development and quality improvement that has characterized the NADYA register from the beginnin

    Anaplasma phagocytophilum MSP4 and HSP70 proteins are involved in interactions with host cells during pathogen infection.

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    Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4) and Heat shock protein 70 (HSP70) were shown to be localized on the bacterial membrane, with a possible role during pathogen infection in ticks. In this study, we hypothesized that A. phagocytophilum MSP4 and HSP70 have similar functions in tick-pathogen and host-pathogen interactions. To address this hypothesis, herein we characterized the role of these bacterial proteins in interaction and infection of vertebrate host cells. The results showed that A. phagocytophilum MSP4 and HSP70 are involved in host-pathogen interactions, with a role for HSP70 during pathogen infection. The analysis of the potential protective capacity of MSP4 and MSP4-HSP70 antigens in immunized sheep showed that MSP4- HSP70 was only partially protective against pathogen infection. This limited protection may be associated with several factors, including the recognition of non-protective epitopes by IgG in immunized lambs. Nevertheless, these antigens may be combined with other candidate protective antigens for the development of vaccines for the control of human and animal granulocytic anaplasmosis. Focusing on the characterization of host protective immune mechanisms and protein-protein interactions at the host-pathogen interface may lead to the discovery and design of new effective protective antigens

    Low sequence diversity of the prion protein gene (PRNP) in wild deer and goat species from Spain

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    Abstract The first European cases of chronic wasting disease (CWD) in free-ranging reindeer and wild elk were confirmed in Norway in 2016 highlighting the urgent need to understand transmissible spongiform encephalopathies (TSEs) in the context of European deer species and the many individual populations throughout the European continent. The genetics of the prion protein gene (PRNP) are crucial in determining the relative susceptibility to TSEs. To establish PRNP gene sequence diversity for free-ranging ruminants in the Northeast of Spain, the open reading frame was sequenced in over 350 samples from five species: Iberian red deer (Cervus elaphus hispanicus), roe deer (Capreolus capreolus), fallow deer (Dama dama), Iberian wild goat (Capra pyrenaica hispanica) and Pyrenean chamois (Rupicapra p. pyrenaica). Three single nucleotide polymorphisms (SNPs) were found in red deer: a silent mutation at codon 136, and amino acid changes T98A and Q226E. Pyrenean chamois revealed a silent SNP at codon 38 and an allele with a single octapeptide-repeat deletion. No polymorphisms were found in roe deer, fallow deer and Iberian wild goat. This apparently low variability of the PRNP coding region sequences of four major species in Spain resembles previous findings for wild mammals, but implies that larger surveys will be necessary to find novel, low frequency PRNP gene alleles that may be utilized in CWD risk control

    Seed storage conditions change the germination pattern of clonal growth plants in Mediterranean salt marshes.

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    8 páginas, 4 tablas, 8 figuras.The effect of salinity level and extended exposure to different salinity and flooding conditions on germination patterns of three saltmarsh clonal growth plants (Juncus subulatus, Scirpus litoralis, and S. maritimus) was studied. Seed exposure to extended flooding and saline conditions significantly affected the outcome of the germination process in a different, though predictable, way for each species, after favorable conditions for germination were restored. Tolerance of the germination process was related to the average salinity level measured during the growth/germination season at sites where established individuals of each species dominated the species cover. No relationship was found between salinity tolerance of the germination process and seed response to extended exposure to flooding and salinity conditions. The salinity response was significantly related to the conditions prevailing in the habitats of the respective species during the unfavorable (nongrowth/nongermination) season. Our results indicate that changes in salinity and hydrology while seeds are dormant affect the outcome of the seed-bank response, even when conditions at germination are identical. Because these environmental-history-dependent responses differentially affect seed germination, seedling density, and probably sexual recruitment in the studied and related species, these influences should be considered for wetland restoration and managementFinancial support from the Spanish Ministry of the Environment (MMA, project 05/99) and the Junta de Andalucía (research group 4086)enabled us to carry out the present work.Peer reviewe

    Seed storage conditions change the germination pattern of clonal growth plants in Mediterranean salt marshes.

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    8 páginas, 4 tablas, 8 figuras.The effect of salinity level and extended exposure to different salinity and flooding conditions on germination patterns of three saltmarsh clonal growth plants (Juncus subulatus, Scirpus litoralis, and S. maritimus) was studied. Seed exposure to extended flooding and saline conditions significantly affected the outcome of the germination process in a different, though predictable, way for each species, after favorable conditions for germination were restored. Tolerance of the germination process was related to the average salinity level measured during the growth/germination season at sites where established individuals of each species dominated the species cover. No relationship was found between salinity tolerance of the germination process and seed response to extended exposure to flooding and salinity conditions. The salinity response was significantly related to the conditions prevailing in the habitats of the respective species during the unfavorable (nongrowth/nongermination) season. Our results indicate that changes in salinity and hydrology while seeds are dormant affect the outcome of the seed-bank response, even when conditions at germination are identical. Because these environmental-history-dependent responses differentially affect seed germination, seedling density, and probably sexual recruitment in the studied and related species, these influences should be considered for wetland restoration and managementFinancial support from the Spanish Ministry of the Environment (MMA, project 05/99) and the Junta de Andalucía (research group 4086)enabled us to carry out the present work.Peer reviewe
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