Study on the seroprevalence of small ruminant brucellosis in and around Bahir Dar, North West Ethiopia

A cross sectional study was carried out from October 2008 to April 2009 to determine the sero-prevalence of brucellosis in small ruminants in and around Bahir Dar, northwest Ethiopia. The sampling method used was purposive sampling technique for districts and simple random for the study animals. A total of 500 serum samples (270 from sheep and 230 from goats) were collected from extensive management system with no history of vaccination. All serum samples were initially screened by Rose-Bengal-Plate Test (RBPT) and positive reactors to RBPT (n=6) were further tested by complement fixation test (CFT) for confirmation. Accordingly, the overall prevalence of brucellosis in small ruminants was 0.4 % (2/500). Rose Bengal Plate Test detected 6 (1.2%) of the samples as seropositive. Up on further testing by CFT only 2 (0.4%) were positive which were adult goats. The seroprevalence of brucellosis was found higher in females (0.4%) than males (0%). Although seropositive animals are low in number, it was found out that animals more than 1 year of age were more affected than others. The result of the present study revealed that the seroprevalence of small ruminant brucellosis in the study area was very low. However, the existence of the disease in the study area has possible risk of spread in the future. Accordingly, elimination of positive seroreactors has been recommended to control the spread of brucellosis in these species of animals

Seroprevalence of Hepatitis B and C Viruses and Their Associated Factors Among Military Personnel at Military Camps in Central Gondar, Ethiopia: A Cross-Sectional Study

Ayanaw Dinku Abebe, Muluneh Assefa, Debaka Belete, Getachew Ferede Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, EthiopiaCorrespondence: Muluneh Assefa, Tel +251944900600, Email [email protected]: Globally, viral hepatitis is a leading cause of death and is highly prevalent in Ethiopia. Military personnel are more vulnerable to hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, and there are no data on such populations in the study area. Therefore, this study aimed to determine the seroprevalence of HBV and HCV infections and their associated factors among military personnel in military camps in Central Gondar, Ethiopia.Materials and Methods: This institutional-based cross-sectional study was conducted with 277 military personnel from April to August 2022 at military camps in Central Gondar, Ethiopia. A systematic random sampling technique was used to select the study participants. Sociodemographic and other relevant data were collected using a structured questionnaire. Five milliliters of venous blood were collected using a vacutainer tube and tested for hepatitis B surface antigens and anti-hepatitis C virus antibodies using an enzyme-linked immunosorbent assay. Data were analyzed using STATA version 14 software and logistic regression models were used to determine the association between HBV/HCV infection and risk factors.Results: Out of 277 participants, the overall seroprevalence of HBV and HCV infections was 19 (6.9%) and 9 (3.3%), respectively. The rate of HBV and HCV co-infection was 2 (0.7%). Having multiple sexual partners (p = 0.048), frequent alcohol use (p = 0.034), hospitalization (p = 0.014), and history of receiving injections from traditional practitioners (p = 0.040) were significant predictors of HBV infection. In contrast, a history of blood transfusion (p = 0.048) and sexually transmitted infections (p = 0.039) were significant risk factors for HCV infection.Conclusion and Recommendations: An intermediate prevalence of HBV and HCV infections was observed among the military personnel. Continuous screening, adherence to healthcare service guidelines, and strengthening of vaccination are crucial for preventing HBV and HCV infections.Keywords: hepatitis B virus, hepatitis C virus, military personnel, Ethiopi

Socio-economic Assessment of Legume Production, Farmer Technology Choice,Market Linkages, Institutions and Poverty in Rural Ethiopia: Institutions, Markets, Policy and Impacts Research Report No. 3

Today, about 1.1 billion people continue to live in extreme poverty on less than US$1 a day. Another 1.6 billion live on between US$1–2 per day. Three out of four poor people in developing countries lived in rural areas in 2002 (WDR 2008). Most depend on agriculture for their livelihoods, directly or indirectly. In much of sub-Saharan Africa, agriculture offers a promising opportunity for spurring growth, overcoming poverty, and enhancing food security. Of the total population of sub-Saharan Africa in 2003, 66% lived in rural areas. More than 90% of rural people in these regions depend on agriculture for their livelihoods. Ryan and Spencer (2001) estimated that three-quarters of the 1.3 billion people living below the poverty line in developing countries lived in rural areas. Of these, an estimated 66% relied on marginal lands (TAC 1997). Broad-based agricultural development through improving the productivity, profi tability and sustainability of smallholder farming is the main pathway out of poverty for millions of poor farm households. Agricultural productivity growth is also vital for stimulating growth in other sectors of the economy. But accelerated growth requires a sharp productivity increase in smallholder farming combined with more effective support to the millions coping as subsistence farmers, many of them in marginal areas. Gallup and Sachs (2000) estimated that, in comparison to temperate regions, productivity was 27% lower in the humid tropics and 42% lower in the dry tropics

High erythromycin-resistant Campylobacter jejuni and C. coli among humans and chickens in Africa

Human Campylobacter spp. enteritis is a common bacterial foodborne illness globally. C. jejuni and C. coli are implicated: chickens are carriers of these bacteria without showing clinical symptoms. The burden of antimicrobial resistant Campylobacter is increasing worldwide. However, there are limited data on the extent of antimicrobial resistance in Africa. Objective: This review aimed to estimate the pooled magnitude of antimicrobial resistance of Campylobacter jejuni and C. coli. Materials and methods: To fill this gap, we conducted a systematic review and meta-analysis following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) Checklist. Literature search used relevant terms and phrases combined using the Boolean operators. The databases PubMed, Google Scholar, Hinnari, and Google were used to find relevant articles. All necessary data were extracted using a standardized data extraction format by two individuals independently. A quality assessment of selected articles was made using Newcastle–Ottawa scale adapted for cross sectional studies. Result: A total 12 studies were identified by this systematic review and meta-analysis. Of 1,142 isolates documented in the papers, 858 (75.1%) were C. jejuni and 284 (24.9%) were C. coli. We found C. jejuni showed lowest resistance level (21.2%) to ciprofloxacin and highest resistance level to trimethoprim-sulfamethoxazole(78.2%) whereas C. coli showed lowest resistance level (18.3%) to ciprofloxacin and highest level of resistance (82.7%) to azithromycin. The overall pooled magnitude of erythromycin resistance C. jejuni and C. coli among in human and chicken subjects was 51.0% and 54.0%, respectively. Conclusion: This systematic review and meta-analysis found high pooled magnitude of erythromycin resistant C. jejuni and C. coli among isolates from both humans and chickens in Africa. More One Health research is needed to give a clear picture on antimicrobial resistance and transmission dynamics of Campylobacter spp. in Africa, covering both humans and poultry

Primary stroke prevention worldwide: translating evidence into action

Stroke is the second leading cause of death and the third leading cause of disability worldwide and its burden is increasing rapidly in low-income and middle-income countries, many of which are unable to face the challenges it imposes. In this Health Policy paper on primary stroke prevention, we provide an overview of the current situation regarding primary prevention services, estimate the cost of stroke and stroke prevention, and identify deficiencies in existing guidelines and gaps in primary prevention. We also offer a set of pragmatic solutions for implementation of primary stroke prevention, with an emphasis on the role of governments and population-wide strategies, including task-shifting and sharing and health system re-engineering. Implementation of primary stroke prevention involves patients, health professionals, funders, policy makers, implementation partners, and the entire population along the life course

Technology generation to dissemination:lessons learned from the tef improvement project

Indigenous crops also known as orphan crops are key contributors to food security, which is becoming increasingly vulnerable with the current trend of population growth and climate change. They have the major advantage that they fit well into the general socio-economic and ecological context of developing world agriculture. However, most indigenous crops did not benefit from the Green Revolution, which dramatically increased the yield of major crops such as wheat and rice. Here, we describe the Tef Improvement Project, which employs both conventional- and molecular-breeding techniques to improve tef\u2014an orphan crop important to the food security in the Horn of Africa, a region of the world with recurring devastating famines. We have established an efficient pipeline to bring improved tef lines from the laboratory to the farmers of Ethiopia. Of critical importance to the long-term success of this project is the cooperation among participants in Ethiopia and Switzerland, including donors, policy makers, research institutions, and farmers. Together, European and African scientists have developed a pipeline using breeding and genomic tools to improve the orphan crop tef and bring new cultivars to the farmers in Ethiopia. We highlight a new variety, Tesfa, developed in this pipeline and possessing a novel and desirable combination of traits. Tesfa\u2019s recent approval for release illustrates the success of the project and marks a milestone as it is the first variety (of many in the pipeline) to be released

Near-infrared spectroscopy applications for high-throughput phenotyping for cassava and yam: a review

Open Access Article; Published online: 12 Aug 2020The review aimed to identify the different high‐throughput phenotyping (HTP) techniques that used for quality evaluation in cassava and yam breeding programmes, and this has provided insights towards the development of metrics and their application in cassava and yam improvements. A systematic review of the published research articles involved the use of NIRS in analysing the quality traits of cassava and yam was carried out, and Scopus, Science Direct, Web of Sciences and Google Scholar were searched. The results of the review established that NIRS could be used in understanding the chemical constituents (carbohydrate, protein, vitamins, minerals, carotenoids, moisture, starch, etc.) for high‐throughput phenotyping. This study provides preliminary evidence of the application of NIRS as an efficient and affordable procedure for HTP. However, the feasibility of using mid‐infrared spectroscopy (MIRS) and hyperspectral imaging (HSI) in combination with the NIRS could be further studied for quality traits phenotyping

Future and potential spending on health 2015-40 : development assistance for health, and government, prepaid private, and out-of-pocket health spending in 184 countries

Background The amount of resources, particularly prepaid resources, available for health can affect access to health care and health outcomes. Although health spending tends to increase with economic development, tremendous variation exists among health financing systems. Estimates of future spending can be beneficial for policy makers and planners, and can identify financing gaps. In this study, we estimate future gross domestic product (GDP), all-sector government spending, and health spending disaggregated by source, and we compare expected future spending to potential future spending. Methods We extracted GDP, government spending in 184 countries from 1980-2015, and health spend data from 1995-2014. We used a series of ensemble models to estimate future GDP, all-sector government spending, development assistance for health, and government, out-of-pocket, and prepaid private health spending through 2040. We used frontier analyses to identify patterns exhibited by the countries that dedicate the most funding to health, and used these frontiers to estimate potential health spending for each low-income or middle-income country. All estimates are inflation and purchasing power adjusted. Findings We estimated that global spending on health will increase from US$9.21 trillion in 2014 to$24.24 trillion (uncertainty interval [UI] 20.47-29.72) in 2040. We expect per capita health spending to increase fastest in upper-middle-income countries, at 5.3% (UI 4.1-6.8) per year. This growth is driven by continued growth in GDP, government spending, and government health spending. Lower-middle income countries are expected to grow at 4.2% (3.8-4.9). High-income countries are expected to grow at 2.1% (UI 1.8-2.4) and low-income countries are expected to grow at 1.8% (1.0-2.8). Despite this growth, health spending per capita in low-income countries is expected to remain low, at $154 (UI 133-181) per capita in 2030 and$195 (157-258) per capita in 2040. Increases in national health spending to reach the level of the countries who spend the most on health, relative to their level of economic development, would mean $321 (157-258) per capita was available for health in 2040 in low-income countries. Interpretation Health spending is associated with economic development but past trends and relationships suggest that spending will remain variable, and low in some low-resource settings. Policy change could lead to increased health spending, although for the poorest countries external support might remain essential.Peer reviewe