Evaluation of tantalum for mercury containment in the SNAP-8 boiler

Corrosion testing of tantalum for mercury containment in SNAP 8 boile

Filtered Noise Can Mimic Low-Dimensional Chaotic Attractors

This contribution presents four results. First, calculations indicate that when examined by the Grassberger-Procaccia algorithm alone, filtered noise can mimic low-dimensional chaotic attractors. Given the ubiquity Of signal filtering in experimental investigations, this is potentially important. Second, a criterion is derived which provides an estimate of the minimum data accuracy needed to resolve the dimension of an attractor. Third, it is shown that a criterion derived by Eckmann and Ruelle [Physica D 56, 185 (1992)] to estimate the minimum number of data points required in a Grassberger-Procaccia calculation can be used to provide a further check on these dimension estimates. Fourth, it is shown that surrogate data techniques recently published by Theiler and his colleagues [in Nonlinear Modeling and Forecasting, edited by M. Casdagli and S. Eubanks (Addison Wesley, Reading, MA, 1992)] can successfully distinguish between linearly correlated noise and nonlinear structure. These results, and most particularly the first, indicate that Grassberger-Procaccia results must be interpreted with far greater circumspection than has previously been the case, and that the algorithm should be used in combination with additional procedures such as calculations with surrogate data. When filtered signals are examined by this algorithm alone, a finite noninteger value of D2 is consistent with low-dimensional chaotic behavior, but it is certainly not a definitive diagnostic of chaos

Filtered Noise Can Mimic Low-Dimensional Chaotic Attractors

This contribution presents four results. First, calculations indicate that when examined by the Grassberger-Procaccia algorithm alone, filtered noise can mimic low-dimensional chaotic attractors. Given the ubiquity Of signal filtering in experimental investigations, this is potentially important. Second, a criterion is derived which provides an estimate of the minimum data accuracy needed to resolve the dimension of an attractor. Third, it is shown that a criterion derived by Eckmann and Ruelle [Physica D 56, 185 (1992)] to estimate the minimum number of data points required in a Grassberger-Procaccia calculation can be used to provide a further check on these dimension estimates. Fourth, it is shown that surrogate data techniques recently published by Theiler and his colleagues [in Nonlinear Modeling and Forecasting, edited by M. Casdagli and S. Eubanks (Addison Wesley, Reading, MA, 1992)] can successfully distinguish between linearly correlated noise and nonlinear structure. These results, and most particularly the first, indicate that Grassberger-Procaccia results must be interpreted with far greater circumspection than has previously been the case, and that the algorithm should be used in combination with additional procedures such as calculations with surrogate data. When filtered signals are examined by this algorithm alone, a finite noninteger value of D2 is consistent with low-dimensional chaotic behavior, but it is certainly not a definitive diagnostic of chaos

Filtered Noise Can Mimic Low-Dimensional Chaotic Attractors

This contribution presents four results. First, calculations indicate that when examined by the Grassberger-Procaccia algorithm alone, filtered noise can mimic low-dimensional chaotic attractors. Given the ubiquity Of signal filtering in experimental investigations, this is potentially important. Second, a criterion is derived which provides an estimate of the minimum data accuracy needed to resolve the dimension of an attractor. Third, it is shown that a criterion derived by Eckmann and Ruelle [Physica D 56, 185 (1992)] to estimate the minimum number of data points required in a Grassberger-Procaccia calculation can be used to provide a further check on these dimension estimates. Fourth, it is shown that surrogate data techniques recently published by Theiler and his colleagues [in Nonlinear Modeling and Forecasting, edited by M. Casdagli and S. Eubanks (Addison Wesley, Reading, MA, 1992)] can successfully distinguish between linearly correlated noise and nonlinear structure. These results, and most particularly the first, indicate that Grassberger-Procaccia results must be interpreted with far greater circumspection than has previously been the case, and that the algorithm should be used in combination with additional procedures such as calculations with surrogate data. When filtered signals are examined by this algorithm alone, a finite noninteger value of D2 is consistent with low-dimensional chaotic behavior, but it is certainly not a definitive diagnostic of chaos

Autofluorescence lifetime augmented reality as a means for real-time robotic surgery guidance in human patients.

Due to loss of tactile feedback the assessment of tumor margins during robotic surgery is based only on visual inspection, which is neither significantly sensitive nor specific. Here we demonstrate time-resolved fluorescence spectroscopy (TRFS) as a novel technique to complement the visual inspection of oral cancers during transoral robotic surgery (TORS) in real-time and without the need for exogenous contrast agents. TRFS enables identification of cancerous tissue by its distinct autofluorescence signature that is associated with the alteration of tissue structure and biochemical profile. A prototype TRFS instrument was integrated synergistically with the da Vinci Surgical robot and the combined system was validated in swine and human patients. Label-free and real-time assessment and visualization of tissue biochemical features during robotic surgery procedure, as demonstrated here, not only has the potential to improve the intraoperative decision making during TORS but also other robotic procedures without modification of conventional clinical protocols

Seasonal Movements, Aggregations and Diving Behavior of Atlantic Bluefin Tuna (Thunnus thynnus) Revealed with Archival Tags

Electronic tags were used to examine the seasonal movements, aggregations and diving behaviors of Atlantic bluefin tuna (Thunnus thynnus) to better understand their migration ecology and oceanic habitat utilization. Implantable archival tags (n = 561) were deployed in bluefin tuna from 1996 to 2005 and 106 tags were recovered. Movement paths of the fish were reconstructed using light level and sea-surface-temperature-based geolocation estimates. To quantify habitat utilization we employed a weighted kernel estimation technique that removed the biases of deployment location and track length. Throughout the North Atlantic, high residence times (167±33 days) were identified in four spatially confined regions on a seasonal scale. Within each region, bluefin tuna experienced distinct temperature regimes and displayed different diving behaviors. The mean diving depths within the high-use areas were significantly shallower and the dive frequency and the variance in internal temperature significantly higher than during transit movements between the high-use areas. Residence time in the more northern latitude high-use areas was significantly correlated with levels of primary productivity. The regions of aggregation are associated with areas of abundant prey and potentially represent critical foraging habitats that have seasonally abundant prey. Throughout the North Atlantic mean diving depth was significantly correlated with the depth of the thermocline, and dive behavior changed in relation to the stratification of the water column. In this study, with numerous multi-year tracks, there appear to be repeatable patterns of clear aggregation areas that potentially are changing with environmental conditions. The high concentrations of bluefin tuna in predictable locations indicate that Atlantic bluefin tuna are vulnerable to concentrated fishing efforts in the regions of foraging aggregations

Paget's disease of bone in two medieval skeletons from Poulton Chapel, Cheshire, UK

Paget's disease of bone (PDB) is a chronic, metabolic disease disrupting normal bone turnover and is reported as one of the most common bone diseases after osteoporosis. PDB is characterised by excessive bone remodelling resulting in bone enlargement, fragility, deformity and additional complications. Typically, PDB affects one or a few bones of the axial skeleton and is commonly recorded in older individuals (over 55 years of age) affecting more males than females. Although PDB has been reported worldwide, there is a high concentration of reported cases in the UK, with a regional hotspot in the northwest of England. This study reviews an adult male (SK463) and female (SK750) with skeletal lesions of PDB from Poulton Chapel, Cheshire. Full macroscopic and radiographic analysis has identified the skeletal distribution of PDB, with up to 75% of both skeletons affected. SK463 presents noticeable anterior bowing to both tibiae, likely the result of PDB. AMS radiocarbon dating and stable isotope analysis performed on teeth samples confirmed that both individuals' dates were medieval, had a mixed/varied diet and were local to the northwest of England. This research adds to the emerging paleopathological literature on PDB, while providing additional support for the identification of a geographical hotspot observed in contemporary populations

Expansion and further delineation of the SETD5 phenotype leading to global developmental delay, variable dysmorphic features, and reduced penetrance

Diagnostic exome sequencing (DES) has aided delineation of the phenotypic spectrum of rare genetic etiologies of intellectual disability (ID). A SET domain containing 5 gene (SETD5) phenotype of ID and dysmorphic features has been previously described in relation to patients with 3p25.3 deletions and in a few individuals with de novo sequence alterations. Herein, we present additional patients with pathogenic SETD5 sequence alterations. The majority of patients in this cohort and previously reported have developmental delay, behavioral/psychiatric issues, and variable hand and skeletal abnormalities. We also present an apparently unaffected carrier mother of an affected individual and a carrier mother with normal intelligence and affected twin sons. We suggest that the phenotype of SETD5 is more complex and variable than previously presented. Therefore, many features and presentations need to be considered when evaluating a patient for SETD5 alterations through DES