DESENVOLVIMENTO DE INDICADORES DE SUSTENTABILIDADE PARA A GESTÃO DE UM CAMPUS UNIVERSITÁRIO UTILIZANDO O BALANCED SCORECARD

Os indicadores de desempenho simbolizam o desempenho das organizações no mercado em que estão inseridas. Mesmo sendo mais constantes em empresas privadas, nas organizações públicas e sem fins lucrativos, a possibilidade de a ferramenta melhorar a administração é reconhecida em perspectivas econômica, social e ambiental. Assim, o trabalho objetivou a criação de indicadores de sustentabilidade utilizando o Balanced Scorecard em um campus universitário, definindo quais medidas, métricas e iniciativas devem ser seguidas para implementar sua estratégia. Desse modo, por meio do planejamento, observações e análise dos ambientes, foi possível criar uma matriz SWOT, para auxiliar na definição dos objetivos do campus; um mapa estratégico, para comunicar os objetivos; e um plano de ação, para a implementação da estratégia. Além disso, os resultados obtidos mostraram a relevância dos métodos de gestão para empresas públicas, além de contribuir com o conhecimento acerca de indicadores de sustentabilidade em universidades.ABSTRACTPerformance indicators symbolize the performance of organizations in the market that they are inserted. Even being more constants in private companies, the ability of the tool to improve the administration in public and non-profit organizations is recognized in economic, social and environmental perspectives. Therefore, this paper aimed the creation of sustainability indicators using Balanced Scorecard on a university campus, defining which measures metrics and initiatives must be pursued to implement its strategy. Thus, after planning, observing and analyzing the environment, it was possible to create a SWOT matrix to assist the definition of the campus goals, a strategic map to communicate the goals and an action planning to implement the strategy. Besides, the results show the importance of management methods for public companies, in addition to contributing to the knowledge of sustainability indicators in universities

Avaliação tridimensional de carcinoma mucoepidermoide em palato duro: relato de caso clínico

Mucoepidermoid carcinoma is of unknown aetiopathology, but it may be related to genetic factors, exposure to ionizing radiation and smoking habits as well. Mucoepidermoid carcinoma is considered the most common malignant neoplasm of salivary glands found in the oral cavity, with its clinical characteristics (e.g., size and shape) favoring the diagnosis and treatment planning. This report describes a case of mucoepidermoid carcinoma which infiltrates into the maxillary sinus and nasal fossa through the palate and highlights the importance of obtaining three-dimensional (3D) images of the tumor for volumetric analysis, thus improving the chances of a successful surgery. We have described the use of the segmentation technique in which the tumor’s volume was calculated to help in predicting surgical outcomes. A 50-year-old patient sought dental treatment because of a purplish swelling in the hard palate region on the left side. Computed tomography examination was performed for visualization of the lesion and incisional biopsy for obtaining a sample, which was sent to anatomopathological study. Histological characteristics of the lesion and presence of neoplastic cells showed positive immunohistochemical reactions for cytokeratin 7 antibody, leading to a diagnosis of mucoepidermoid carcinoma. In view of the malignant characteristics of the lesion, the patient was referred to a head and neck surgeon for treatment.O carcinoma mucoepidermoide possui etiopatogenia desconhecida, porém, pode ser relacionado a fatores genéticos, exposição à radiação ionizante e também ao hábito de fumar. Há a possibilidade de crescer de forma assintomática. É considerado a neoplasia maligna de glândulas salivares mais comum encontrada na cavidade oral e as suas características clínicas (por exemplo, sítio de predileção e forma como se apresenta) favorecem um melhor diagnóstico e planejamento de intervenção. Este relato apresenta um caso de carcinoma mucoepidermoide que se infiltra no seio maxilar e fossa nasal através do palato e destaca a importância da obtenção de imagens tridimensionais (3-D) do tumor para análise volumétrica e melhoria das chances de sucesso cirúrgico. Descrevemos o uso de uma técnica pictórica em que o volume do tumor foi calculado para ajudar a prever os resultados cirúrgicos. A paciente de 50 anos procurou atendimento odontológico devido ao aumento de volume com coloração arroxeada em região de palato duro do lado esquerdo, foi realizado o exame de Tomografia Computadorizada onde se verificou a lesão. A partir da biópsia incisional e o encaminhamento para avaliação anatomopatológica, suas características histológicas e as células neoplásicas mostraram-se positivas para as reações de imunohistoquímica contra anticorpo citoqueratina sete, o que concluiu o diagnóstico de carcinoma mucoepidermoide. Diante das características malignas da lesão, a paciente foi encaminhada para médico cirurgião de cabeça e pescoço para tratamento

High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort

Background: The city of Manaus, Brazil, has seen two collapses of the health system due to the COVID-19 pandemic. We report anti-SARS-CoV-2 nucleocapsid IgG antibody seroconversion rates and associated risk factors in Manaus residents before the second wave of the epidemic in Brazil. Methods: A convenience sample of adult (aged ≥18 years) residents of Manaus was recruited through online and university website advertising into the DETECTCoV-19 study cohort. The current analysis of seroconversion included a subgroup of DETECTCoV-19 participants who had at least two serum sample collections separated by at least 4 weeks between Aug 19 and Oct 2, 2020 (visit 1), and Oct 19 and Nov 27, 2020 (visit 2). Those who reported (or had no data on) having a COVID-19 diagnosis before visit 1, and who were positive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at visit 1 were excluded. Using an in-house ELISA, the reactivity index (RI; calculated as the optical density ratio of the sample to the negative control) for serum anti-SARS-CoV-2 nucleocapsid IgG antibodies was measured at both visits. We calculated the incidence of seroconversion (defined as RI values ≤1·5 at visit 1 and ≥1·5 at visit 2, and a ratio >2 between the visit 2 and visit 1 RI values) during the study period, as well as incidence rate ratios (IRRs) through cluster-corrected and adjusted Poisson regression models to analyse associations between seroconversion and variables related to sociodemographic characteristics, health access, comorbidities, COVID-19 exposure, protective behaviours, and symptoms. Findings: 2496 DETECTCoV-19 cohort participants returned for a follow-up visit between Oct 19 and Nov 27, 2020, of whom 204 reported having COVID-19 before the first visit and 24 had no data regarding previous disease status. 559 participants were seropositive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at baseline. Of the remaining 1709 participants who were seronegative at baseline, 71 did not meet the criteria for seroconversion and were excluded from the analyses. Among the remaining 1638 participants who were seronegative at baseline, 214 showed seroconversion at visit 2. The seroconversion incidence was 13·06% (95% CI 11·52–14·79) overall and 6·78% (5·61–8·10) for symptomatic seroconversion, over a median follow-up period of 57 days (IQR 54–61). 48·1% of seroconversion events were estimated to be asymptomatic. The sample had higher proportions of affluent and higher-educated people than those reported for the Manaus city population. In the fully adjusted and corrected model, risk factors for seroconversion before visit 2 were having a COVID-19 case in the household (IRR 1·49 [95% CI 1·21–1·83]), not wearing a mask during contact with a person with COVID-19 (1·25 [1·09–1·45]), relaxation of physical distancing (1·31 [1·05–1·64]), and having flu-like symptoms (1·79 [1·23–2·59]) or a COVID-19 diagnosis (3·57 [2·27–5·63]) between the first and second visits, whereas working remotely was associated with lower incidence (0·74 [0·56–0·97]). Interpretation: An intense infection transmission period preceded the second wave of COVID-19 in Manaus. Several modifiable behaviours increased the risk of seroconversion, including non-compliance with non-pharmaceutical interventions measures such as not wearing a mask during contact, relaxation of protective measures, and non-remote working. Increased testing in high-transmission areas is needed to provide timely information about ongoing transmission and aid appropriate implementation of transmission mitigation measures. Funding: Ministry of Education, Brazil; Fundação de Amparo à Pesquisa do Estado do Amazonas; Pan American Health Organization (PAHO)/WHO.World Health OrganizationRevisión por pare

Alimentação como fator de risco para câncer de intestino em universitários

Objective: To analyze the diet quality of university students as a risk factor for bowel cancer. Methods: Cross-sectional study with 100 university students of the Gastronomy undergraduate course of a private teaching institution in Montes Claros, Minas Gerais. The body mass index (BMI) was assessed. Data on eating behavior, physical activity practice, and feeding frequency was collected. Descriptive analysis was conducted. Results: From the results, it was verified that 46% (n=46) of the students presented increased body mass, that is, BMI ≥ 25 kg/m2 (overweight and obesity). Analysis of the eating habits showed body weight change in 44% of the interviewees; of these, 25% presented body mass gain. Among the interviewees, 41% reported consuming encased meats, pizzas and fast foods, among others, and 57% reported consuming processed foods 1 to 3 times a week. High-sugar foods (sugar-sweetened coffee, soft drinks and chocolate) were daily consumed by 71%, 30% and 24% of the participants. The consumption of grains (chia, flaxseed and quinoa) was reported by 7% of them. Conclusion: High consumption of processed and/or industrialized foods was observed, with high contents of fat and sugar, in conjunction with low intake of grains. This dietary situation associated with a sedentary lifestyle represent risk factors for the onset of a neoplasia.Objetivo: Analizar la calidad de la alimentación de universitarios como factor de riesgo para el cáncer de intestino. Métodos: Estudio transversal con 100 universitarios del curso de Gastronomía de una institución privada de Montes Claros, Minas Gerais. Se verificó el índice de masa corporal (IMC). Se recogieron datos de la conducta alimentaria, la práctica de actividad física y la frecuencia de alimentación. Se utilizó un análisis descriptivo. Resultados: A partir de los resultados se verificó que el 46% (n=46) de los estudiantes tenían la masa corporal elevada o sea el IMC ≥ 25 kg/m2 (sobrepeso y obesidad). El análisis de los hábitos alimentarios ha demostrado cambio en el peso corporal en el 44% (n= 44) de los entrevistados, de estos el 25% presentó ganancia de la masa corporal. De entre los entrevistados, el 41% relató el consumo de embutidos, pizzas y fast foods, entre otros, y el 57% afirmó consumir alimentos industrializados entre 1 y 3 veces a la semana. Los alimentos ricos en azúcar (el café con azúcar, los refrescos y el chocolate) eran consumidos a diario por el 71%, el 30% y el 24% de los participantes. El consumo de granos (la chía, la linaza y la quinoa) fue relatado por el 7%. Conclusión: Se observó elevado consumo de alimentos procesados y/o industrializados con elevada proporción de grasas y azucares asociado a una baja ingesta de granos. Ese conjunto de alimentos asociado con un estilo de vida sedentario son factores de riesgo para la instalación de un cuadro de neoplasia.Objetivo: Analisar a qualidade da alimentação de universitários como fator de risco para câncer de intestino. Métodos: Estudo transversal com 100 universitários do curso de Gastronomia de uma instituição de ensino privada em Montes Claros, Minas Gerais. Aferiu-se o índice de massa corporal (IMC). Coletaram-se o comportamento alimentar, prática de atividade física e a frequência alimentar. Utilizou-se a análise descritiva. Resultados: A partir dos resultados, verificou-se que 46% (n=46) dos estudantes estavam com a massa corporal elevada, ou seja, IMC ≥ 25 kg/m2 (sobrepeso e obesidade). A análise dos hábitos alimentares demonstrou mudança de peso corporal em 44% dos entrevistados, destes 25% apresentou ganho de massa corporal. Dentre os entrevistados, 41% alegou consumir embutidos, pizzas e fast foods dentre outros, e 57% relatou consumir alimentos industrializados de 1 a 3 vezes por semana. Os alimentos ricos em açúcar (café com açúcar, refrigerantes e chocolate) eram consumidos diariamente por 71%, 30% e 24% dos participantes. O consumo de grãos (chia, linhaça e quinoa) foi relatado por 7%. Conclusão: Observou-se alto consumo de alimentos processados e/ou industrializados com alto teor de gorduras e açúcares, juntamente com uma baixa ingestão de grãos. Essa conjuntura alimentar associada a um estilo de vida sedentário são fatores de risco para a instalação de um quadro de neoplasia

“Traditional” and “Healthy” Dietary Patterns Are Associated with Low Cardiometabolic Risk in Brazilian Subjects

This study aimed at determining the dietary patterns and investigating their association with cardiometabolic risk markers in a brazilian population at risk. This transversal study was carried out with data of 265 patients (n = 123 M/172 W, age 42 ± 16 years) of the Cardiovascular Health Care Program—PROCARDIO-UFV, Brazil—who had their first appointment between 2012 and 2017. A 24-hour recall was applied. The dietary patterns were determined by Principal Component Analysis. Anthropometric, clinical-metabolic, sociodemographic, and lifestyle data were collected through medical record analysis. Five patterns were identified: “Traditional”, “Caloric”, “Unhealthy”, “Healthy,” and “Healthy Snacks”. In bivariate analysis, the “Healthy” pattern was negatively associated with WC (waist circunference), BMI (body mass index), WHR (waist-to-hip ratio), SBP (systolic blood pressure), fasting glucose, TG/HDL, LDL/HDL, and TG/HDL values and positively to HDL. The “Traditional” pattern was positively associated with adiposity indicators (WC, BMI, and WHR) and negatively associated with body fat, TyG (triglyceride-glucose index), HDL, and LDL (P<0.05). However, in adjusted models of Poisson regression, individuals with positive factor score (higher adherence) in the “Traditional” and “Healthy” patterns had less occurrence of abdominal obesity (PR 0.85; 95% CI 0.74–0.99/PR 0.88; 95% CI 0.02–0.76), as well as dyslipidemia (PR 0.06; 95% CI 0.02–0.51/PR 0.03; 95% CI 0.01–0.27), diabetes (PR 0.05; 95% CI 0.01–0.45/PR 0.02; 95% CI 0.01–021), and hypertension (PR 0.06; 95% CI 0.02–0.50/PR 0.02; 95% CI 0.01–0.21). A greater adherence to the “Healthy” pattern was associated with lower values to cardiometabolic risk markers and less occurrence of chronic diseases, while the “Traditional” pattern presented contradictory results

Ketamine plus Alcohol: What We Know and What We Can Expect about This

Drug abuse has become a public health concern. The misuse of ketamine, a psychedelic substance, has increased worldwide. In addition, the co-abuse with alcohol is frequently identified among misusers. Considering that ketamine and alcohol share several pharmacological targets, we hypothesize that the consumption of both psychoactive substances may synergically intensify the toxicological consequences, both under the effect of drugs available in body systems and during withdrawal. The aim of this review is to examine the toxicological mechanisms related to ketamine plus ethanol co-abuse, as well the consequences on cardiorespiratory, digestive, urinary, and central nervous systems. Furthermore, we provide a comprehensive discussion about the probable sites of shared molecular mechanisms that may elicit additional hazardous effects. Finally, we highlight the gaps of knowledge in this area, which deserves further research

Ketamine plus alcohol: what we know and what we can expect about this.

Drug abuse has become a public health concern. The misuse of ketamine, a psychedelic substance, has increased worldwide. In addition, the co-abuse with alcohol is frequently identified among misusers. Considering that ketamine and alcohol share several pharmacological targets, we hypothesize that the consumption of both psychoactive substances may synergically intensify the toxicological consequences, both under the effect of drugs available in body systems and during withdrawal. The aim of this review is to examine the toxicological mechanisms related to ketamine plus ethanol co-abuse, as well the consequences on cardiorespiratory, digestive, urinary, and central nervous systems. Furthermore, we provide a comprehensive discussion about the probable sites of shared molecular mechanisms that may elicit additional hazardous effects. Finally, we highlight the gaps of knowledge in this area, which deserves further research

High Rates of Sexualized Drug Use or Chemsex among Brazilian Transgender Women and Young Sexual and Gender Minorities

(1) Background: We aimed to estimate sexualized drug use (SDU) prevalence and its predictors among sexual and gender minorities. (2) Methods: We used an online and on-site survey to enroll sexual/gender minorities people between October&ndash;December/2020, and multivariate logistic regression to obtain SDU correlates. (3) Results: We enrolled 3924 individuals (280 transgender women [TGW], 3553 men who have sex with men [MSM], and 91 non-binary), 29.0% currently on pre-exposure prophylaxis (PrEP). SDU prevalence was 28.8% (95% confidence interval [CI] 27.4&ndash;30.2). TGW had 2.44-times increased odds (95%CI 1.75&ndash;3.39) of engaging in SDU compared to MSM, regardless of PrEP use. PrEP use (aOR 1.19, 95%CI 1.00&ndash;1.41), South/Southeast region (aOR 1.26, 95%CI 1.04&ndash;1.53), younger age (18&ndash;24 years: aOR 1.41, 95%CI 1.10&ndash;1.81; 25&ndash;35 years: aOR 1.24, 95%CI 1.04&ndash;1.53), white race/color (aOR 1.21, 95%CI 1.02&ndash;1.42), high income (aOR 1.32, 95%CI 1.05&ndash;1.67), binge drinking (aOR 2.66, 95%CI 2.25&ndash;3.14), &gt;5 sexual partners (aOR 1.88, 95%CI 1.61&ndash;2.21), condomless anal sex (aOR 1.49, 95%CI 1.25&ndash;1.79), self-reported sexually transmitted infection (aOR 1.40, 95%CI 1.14&ndash;1.71), and higher perceived HIV-risk (aOR 1.37, 95%CI 1.14&ndash;1.64) were associated with SDU. (4) Conclusions: TGW had the highest SDU odds. SDU may impact HIV vulnerability among key populations and should be addressed in HIV prevention approaches