192 research outputs found

    STEAM and Environmental Justice in an Interdisciplinary Context

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    This course proposes an interdisciplinary perspective, envisions unique synergies between environmental justice concepts and STEAM projects on mining, and aims to solidify a foundation based on justice, equity, equality, and empathy for STEM students and faculty. Our (S)TEAM made of professors in three academic departments underscores interdisciplinary and diversity connections through an interdisciplinary team-taught course, units on environmental justice related to mining, teaching of literary texts, and STEAM projects. We also involved faculty, alumni, and our campus and city community through STEAM exhibits

    Cavity-enhanced Evanescent-wave Chemical Sensing Using Microresonators

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    The purpose of this research was to examine fused silica microresonators into which light was evanescently coupled into whispering-gallery modes (WGMs) using a tapered optical fiber. The high quality factor (Q/) of these microcavities makes a sharp dip in a frequency scan when the resonance criterion is met. The depth and width of the dip are determined by the coupling coefficient between the coupler and the microsphere, and the intrinsic loss of the cavity. The use of these modes as sensors was examined. Introducing an absorber in the evanescent field of the microresonator's WGM changes the round-trip loss of the cavity and hence a change in dip depth, width, and frequency of a WGM is observed. Absorbers studied in the dissertation include methane, methyl chloride, ethylene, indocyanine green dye in methanol at 800 nm, SDA2072 in methanol at 1650 nm, and ruthenium complex in water. Less than nM concentrations of dye in solution can be easily detected. Trace gas amounts in atmosphere could also be detected.Department of Physic

    Roots to Routes: Contemporary indigenous fiction by women writers in the United States, Canada, Australia, and New Zealand

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    Scope and Method of Study: This study analyzes the role of place and its cultural significance in the fiction of eight contemporary Indigenous women writers from the United States, Canada, Australia, and New Zealand, four former colonies of the British Empire. I argue that places are social and cultural constructions that regenerate themselves as a result of their inhabitants' active participation. At the same time, the inhabitants' experiences in specific places aid them in renewing their relationships with their tribal and national histories and cultures. Places show that Indigenous people can survive in a postcolonial world, heal, regain homes and rituals, and subsequently build new homes and create new traditions.Findings and Conclusions: Responding to postcolonial scholarship, which focuses on the violence of colonialism and on Indigenous people's loss of land and family members, I have found a different approach to place which deals with such losses. I suggest that even the most recent definitions of place can be revised and expanded so that they include an internalized and creative component, one which is shaped by people's imaginations and memories and also by their experiences of places. The Indigenous writers I examine show that places are not only concrete locations but also internalized processes that result from individuals' mental interpretations. This new way of thinking about place is relevant to many Indigenous people who lost their land and their family members because it implies an approach to place that involves going beyond one's physical presence in a particular location

    Reconstrucción de neoglande con colgajo uretral para el tratamiento quirúrgico de calcifilaxis peniana

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    ResumenIntroducciónLa arteriolopatía urémica calcificante, también conocida como calcifilaxis, es una entidad caracterizada por la presencia de áreas de necrosis isquémica junto con extensas calcificaciones de la capa media de las arteriolas de la piel; la etiopatogenia es compleja, las formas de presentación y evolución son diversas. La calcifilaxis del pene es una entidad muy rara. El dolor y la ulceración del glande es una de sus manifestaciones clínicas iniciales, el diagnóstico en estas etapas es difícil de establecer y el manejo debe ser integral. El tratamiento médico seguido del manejo quirúrgico se establecerá de acuerdo a la etapa y evolución de la enfermedad.La reconstrucción aislada del glande se recomienda tras una amputación traumática o quirúrgica por alguna enfermedad benigna o maligna. El objetivo es conseguir una apariencia estética razonable, permitir una micción fisiológica y tratar de conservar la mayor cantidad de tejido eréctil. En pacientes con calcifilaxis peniana, el manejo quirúrgico convencional es radical y consiste en falectomía parcial o total según sea el caso. El manejo conservador ha sido reportado mediante la desbridación de las lesiones ulcerosas en pene, tratamiento local y vigilancia.Caso clínicoSe presenta el caso de un paciente masculino de 59 años de edad con insuficiencia renal crónica en tratamiento con hemodiálisis, hospitalizado por cuadro de 5 días de evolución con úlcera dolorosa en glande, refractaria a manejo analgésico. Se realizó biopsia escisional de la lesión con estudio histopatológico confirmando calcifilaxis. Se plantea a paciente falectomía parcial la cual rechaza por lo que se ofrece reconstrucción en un tiempo como opción terapéutica.ConclusiónUtilizar injertos o colgajos de piel para realizar la reconstrucción del pene en pacientes con calcifilaxis no representa una opción viable. Por su gran aporte vascular, la uretra representa una buena opción de reconstrucción en pacientes con calcifilaxis en etapa inicial. La selección y evaluación de los pacientes debe ser muy cautelosa para que los resultados estéticos y funcionales sean aceptables.AbstractIntroductionCalcific uremic arteriolopathy, also known as calciphylaxis, is an entity characterized by areas of ischemic necrosis with extensive calcifications of the middle layer of the skin arterioles. Its etiopathogenesis is complex and its forms of presentation and progression are diverse. Calciphylaxis of the penis is an extremely rare entity. Pain and ulceration of the glans penis are initial clinical manifestations and diagnosis at these stages is difficult. Management should be comprehensive. Medical treatment, followed by surgical management, is established according to disease stage and progression.Isolated reconstruction of the glans penis is recommended when there is traumatic amputation or a surgical one due to benign or malignant disease. The goal is to obtain a reasonably esthetic appearance, to have physiologic micturition, and to spare the greatest amount of erectile tissue possible. Conventional surgical management in patients with penile calciphylaxis is radical and consists of partial or total phallectomy, depending on the case. Conservative management through ulcerous penile lesion debridement, local treatment, and surveillance has been reported.Case reportA 59-year-old man with chronic renal insufficiency in hemodialysis treatment was hospitalized for symptoms of 5-day progression of a painful ulcer on the glans penis that was refractory to analgesics. An excisional biopsy of the lesion was taken and the histopathologic study confirmed calciphylaxis. Partial phallectomy was suggested to the patient, but he rejected it, and so single stage reconstruction was offered as a therapeutic option.ConclusionThe use of skin grafts or flaps for penile reconstruction in patients with calciphylaxis is not a viable option. Because of its large blood supply, the urethra is a good reconstruction option in patients with initial-stage calciphylaxis. Patient selection and evaluation must be carried out with great care in order to have acceptable functional and esthetic results

    Ejercicio profesional del diseño industrial 2 : un acercamiento al análisis de algunas de las especialidades más dinámicas en México

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    1 archivo PDF (153 páginas)Con este segundo tomo de este título, renace el espíritu de un proyecto académico del Grupo de Investigación DeiGmas que busca promover el diálogo entre la comunidad del diseño, en torno a la construcción de conceptos disciplinarios propios. El valor esencial de la presente publicación radica en que ofrece a los lectores una conjunción de ideas de profesionales experimentados en diversas especialidades del diseño industrial, sustentadas en su experiencia concreta del quehacer cotidiano en organizaciones nacionales de distinta índole

    A comprehensive experimental study of whispering gallery modes in a cylindrical microresonator excited by a tilted fiber taper

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    Whispering gallery modes (WGMs) excitation in a cylindrical microresonator formed by a section of silica optical fiber has been studied. Evanescent light coupling into the microresonator is realized using a tapered optical fiber, fabricated by a microheater brushing technique. Several types of silica fibers with different diameters are studied as microresonators, and the influence of the resonator's diameter on the excitation of WGMs is investigated. The excitation of WGMs in a cylindrical fiber resonator were studied with changes to the tilt angle between the microcylinder and the fiber taper in the range of angles from a perpendicular position (0°) to large tilt angles (24°). The evolution of the fiber taper transmission spectrum with the change of the tilt angle results in changes in the intensity, broadening of and a blue shift in the WGM resonance spectra. Overall losses in the taper transmission spectrum decrease with the increase of the taper tilt angle from its perpendicular position, followed by a complete disappearance of the WGM resonances at large tilt angles greater than 20°

    Whispering Gallery Modes in Standard Optical Fibres for Fibre Profiling Measurements and Sensing of Unlabelled Chemical Species

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    Whispering gallery mode resonances in liquid droplets and microspheres have attracted considerable attention due to their potential uses in a range of sensing and technological applications. We describe a whispering gallery mode sensor in which standard optical fibre is used as the whispering gallery mode resonator. The sensor is characterised in terms of the response of the whispering gallery mode spectrum to changes in resonator size, refractive index of the surrounding medium, and temperature, and its measurement capabilities are demonstrated through application to high-precision fibre geometry profiling and the detection of unlabelled biochemical species. The prototype sensor is capable of detecting unlabelled biomolecular species in attomole quantities

    Evaluating synergy between marbofloxacin and gentamicin in Pseudomonas aeruginosa strains isolated from dogs with otitis externa

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    The aim of this study was to determine antimicrobial susceptibility of Pseudomonas aeruginosa strains to marbofloxacin and gentamicin, and investigate the possible synergistic, additive, indifferent or antagonistic effects between the two agents. P. aeruginosa strains can develop resistance quickly against certain antibiotics if used alone, thus the need emerges to find synergistic combinations. A total of 68 P. aeruginosa strains isolated from dogs were examined. In order to describe interactions between marbofloxacin and gentamicin the checkerboard microdilution method was utilized. The MICs (minimum inhibitory concentrations) for marbofloxacin and gentamicin were in the range 0.25–64 mg/L and 0.25–32 mg/L, respectively. The combination of marbofloxacin and gentamicin was more effective with a MIC range of 0.031–8 mg/L and a MIC90 of 1 mg/L, compared to 16 mg/L for marbofloxacin alone and 8 mg/L for gentamicin alone. The FIC (fractional inhibitory concentration) indices ranged from 0.0945 (pronounced synergy) to 1.0625 (indifference). Synergy between marbofloxacin and gentamicin was found in 33 isolates. The mean FIC index is 0.546, which represents a partial synergistic/additive effect close to the full synergy threshold. In vitro results indicate that marbofloxacin and gentamicin as partially synergistic agents may prove clinically useful in combination therapy against P. aeruginosa infections. Although marbofloxacin is not used in the human practice, the interactions between fluoroquinolones and aminoglycosides may have importance outside the veterinary field
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