How Is the Language of Imagery in lyric’s of Amir Khosro Dehlavi

Whenever there is an amazing resurrection in a nation’s language which leads to create an artistic masterpiece in that language, it is called literature. For this reason, we can differentiate between literary language and daily or spoken language. Writers and literates from various countries will often try to utilize a literary approach in order to make their utterances and poems more attractive and popular through the use of written imagery and artily, illustratively capturing the emotion of the written words. Amir Khosro Dehlavi; who is a well-known Hindi poet, has mastered the illustrative nature of the Farsi language to compose his euphonious lyric poems. In reviewing his work, we will try to evaluate the context of his poems and the way he has used imaginary and artily language structures, consisting of words, combinations, sentences and phrases in his lyrics, as well as evaluating the way he introduces an imagery approach to his poems

Artificial intelligence ethics in precision oncology: balancing advancements in technology with patient privacy and autonomy

Precision oncology is a rapidly evolving field that uses advanced technologies to deliver personalized cancer care based on a patient’s unique genetic and clinical profile. The use of artificial intelligence (AI) in precision oncology has shown great potential to improve diagnosis, treatment planning, and treatment outcomes. However, the integration of AI in precision oncology also raises important ethical considerations related to patient privacy, autonomy, and protection from bias. In this opinion paper, an overview is provided of previous studies that have explored the use of AI in precision oncology and the ethical considerations associated with this technology. The conclusions of these studies are compared, and the importance of approaching the use of AI in precision oncology with caution is emphasized. It is stressed that patient privacy, autonomy, and protection from bias should be made central to the development and use of AI in precision oncology. Clear guidelines and regulations must be established to ensure that AI is used ethically and for the benefit of patients. The use of AI in precision oncology has the potential to revolutionize cancer care, but it should be ensured that it striked a balance between advancements in technology and ethical considerations. In conclusion, the use of AI in precision oncology is a promising development that has the potential to improve cancer outcomes. However, ethical considerations related to patient privacy, autonomy, and protection from bias must be central to the development and use of AI in precision oncology

Job stress among iranian prison employees

Background: Exposure to job stress causes deleterious effects on physical and mental health of employees and productivity of organizations. Objective: To study work-related stressors among employees of prisons of Ilam, western Iran. Methods: In a cross-sectional study conducted from July to October 2013, 177 employees of Ilam prisons and security-corrective measures organization were enrolled in this study. The UK Health and Safety Executive Organization 35-item questionnaire for assessment of occupational stress was used to determine job stress among the studied employees. Results: Job stress was highest among employees of “correction and rehabilitation center” of Ilam province followed by “Dalab vocational training center.” There was no significant relationship between occupational stress and age, work experience, level of education, marital status, sex of employees, and obesity. Conclusion: Employees of prisons, for their nature of job and work environment, are exposed to high level of occupational stress. © 2014, Int J Occup Environ Med. All Rights Reserved

Synthesis and Characterization of Tetracycline Loaded Methionine-Coated NiFe2O4 Nanoparticles for Anticancer and Antibacterial Applications

In the present study, nickel ferrite (NiFe(2)O(4))-based smart magnetic nanoparticles were fabricated and coated with methionine. Physiochemical characterization of the obtained Met-NiFe(2)O(4) nanoparticles revealed the presence of methionine coating over the nanoparticle surface. Drug release study indicated that Tet-Met-NiFe(2)O(4) nanoparticles possess pH-responsive controlled drug release behavior for tetracycline (Tet). The drug loading content for Tet was found to be 0.27 mg/L of nanoparticles. In vitro cytotoxicity test showed that the Met-NiFe(2)O(4) nanoparticles is biocompatible. Moreover, this magnetic nanostructured material shown strong anticancer property as these nanomaterials significantly reduced the viability of A375 cells when compared to free Tet solution. In addition, Tet-Met-NiFe(2)O(4) nanoparticles also showed strong antibacterial activity against different bacterial pathogens

Combinational system of lipid-based nanocarriers and biodegradable polymers for wound healing: an updated review

Skin wounds have imposed serious socioeconomic burdens on healthcare providers and patients. There are just more than 25,000 burn injury-related deaths reported each year. Conventional treatments do not often allow the re-establishment of the function of affected regions and structures, resulting in dehydration and wound infections. Many nanocarriers, such as lipid-based systems or biobased and biodegradable polymers and their associated platforms, are favorable in wound healing due to their ability to promote cell adhesion and migration, thus improving wound healing and reducing scarring. Hence, many researchers have focused on developing new wound dressings based on such compounds with desirable effects. However, when applied in wound healing, some problems occur, such as the high cost of public health, novel treatments emphasizing reduced healthcare costs, and increasing quality of treatment outcomes. The integrated hybrid systems of lipid-based nanocarriers (LNCs) and polymer-based systems can be promising as the solution for the above problems in the wound healing process. Furthermore, novel drug delivery systems showed more effective release of therapeutic agents, suitable mimicking of the physiological environment, and improvement in the function of the single system. This review highlights recent advances in lipid-based systems and the role of lipid-based carriers and biodegradable polymers in wound healing

A Review on biomedical application of polysaccharide-based hydrogels with a focus on drug delivery systems

Over the last years of research on drug delivery systems (DDSs), natural polymer-based 18 hydrogels have shown many scientific advances due to their intrinsic properties and a wide variety 19 of potential applications. While drug efficacy and cytotoxicity play a key role, adopting a proper 20 DDS is crucial to preserve the drug along the route of administration and possess desired therapeu-21 tic effect at the targeted site. Thus, drug delivery technology can be used to overcome the difficulties 22 of maintaining drugs at a physiologically related serum concentration for prolonged periods. Due 23 to their outstanding biocompatibility, polysaccharides have been thoroughly researched as a bio-24 logical material for DDS advancement. To formulate a modified DDS, polysaccharides can cross-25 link with different molecules, resulting in hydrogels. According to our recent findings, targeted 26 drug delivery at a certain spot occurs due to external stimulation like temperature, pH, glucose, or 27 light. As an adjustable biomedical device, the hydrogel has tremendous potential for nanotech ap-28 plications in the involved health area like pharmaceutical and biomedical engineering. An overview 29 of hydrogel characteristics and functionalities is provided in this review. We focus on discussing 30 the various kinds of hydrogel-based on their potential for effectively delivering drugs that are made 31 of polysaccharides

Folate-Targeted Curcumin-Loaded Niosomes for Site-Specific Delivery in Breast Cancer Treatment: In Silico and In Vitro Study

As the most common cancer in women, efforts have been made to develop novel nanomedicine-based therapeutics for breast cancer. In the present study, the in silico curcumin (Cur) properties were investigated, and we found some important drawbacks of Cur. To enhance cancer therapeutics of Cur, three different nonionic surfactants (span 20, 60, and 80) were used to prepare various Cur-loaded niosomes (Nio-Cur). Then, fabricated Nio-Cur were decorated with folic acid (FA) and polyethylene glycol (PEG) for breast cancer suppression. For PEG-FA@Nio-Cur, the gene expression levels of Bax and p53 were higher compared to free drug and Nio-Cur. With PEG-FA-decorated Nio-Cur, levels of Bcl2 were lower than the free drug and Nio-Cur. When MCF7 and 4T1 cell uptake tests of PEG-FA@Nio-Cur and Nio-Cur were investigated, the results showed that the PEG-FA-modified niosomes exhibited the most preponderant endocytosis. In vitro experiments demonstrate that PEG-FA@Nio-Cur is a promising strategy for the delivery of Cur in breast cancer therapy. Breast cancer cells absorbed the prepared nanoformulations and exhibited sustained drug release characteristics

Light Intensity and Ultraviolet Radiation in the Libraries and Computer Sites of Ilam Universities

Background: Light is an important and adjustable physical factor in the job environment.This study aimed to determine the intensity of natural and mixed light and also the level of ultraviolet radiation in libraries and computer sites of Ilam universities in spring 2011. Methods: In this cross-sectional study, 10 libraries, 16 study saloons, and 7 computer sites were selected. Luminosity assessing form was used to collect related data about selected places. Light intensity measuring device (Hanger-EC1) and ultraviolet radiation­ intensity measuring device (Hanger- EC1) were used to measure these two variables. Measurement was performed according to the suggested method by IESNA and data analysis was done by SPSS17 software. Results: Mean general light intensity of libraries in mixed and natural conditions, were respectively 235.2±140.2 lux and 198.2±154.6 lux. Maximum mean of Ultraviolet Radiation in mixed and natural conditions were 0.012±0.0131 and 0.008±0.007 w/m2 respectively. These show that light intensity and ultraviolet radiation in the majority of studied units were significantly higher in mixed conditions (natural and artificial light) than in the natural conditions. Conclusion: Improper design and light source selection, oldness of the constructions, and altering the applications of the constructions from administrative places into libraries, studying saloons, and computer sites have caused light intensity lower than the standard levels in these places. Therefore, redesigning the light systems is necessary. Keywords: Light intensity, Ultraviolet radiation, Library, Ila

Penerapan Model Discovery Learning untuk Meningkatkan Motivasi dan Hasil Belajar Siswa Kelas X TKJ Pada Mata Pelajaran Pemrograman Dasar di SMK Negeri 1 Cerme Gresik

ABSTRAK   Haniffarasati Q, Afina. 2016. Penerapan Model Discovery Learning untuk Meningkatkan Motivasi dan Hasil Belajar Siswa Kelas X TKJ Pada Mata Pelajaran Pemrograman Dasar di SMK Negeri 1 Cerme Gresik. Skripsi, Fakultas Teknik. Universitas Negeri Malang. Pembimbing: (I) Dr. Ir. H. Syaad Patmanthara, M.Pd. (II) M. Jauharul Fuady, S.T., M.T.   Kata Kunci: Discovery Learning, motivasi belajar, hasil belajar Permasalahan yang ditemukan pada 32 siswa kelas X TKJ 1 matapelajaran Pemrograman Dasar di SMK Negeri 1 Cerme Gresik, yaitu: (1) hasil belajar 15 siswa masih dibawah Kriteria Ketuntasan Minimal (KKM), (2) motivasi belajar 17 siswa masih rendah, dan (3) model pembelajaran Project Based Learning yang digunakan guru tidak sesuai dengan karakter siswa. Dari permasalahan tersebut, peneliti mencoba menerapkan model pembelajaran yang cocok untuk meningkatkan motivasi dan hasil belajar siswa pada matapelajaran Pemrograman Dasar yaitu model Discovery Learning. Model Discovery Learning mampu membantu siswa untuk menemukan konsep melalui serangkaian data atau informasi yang diperoleh dari suatu pengamatan atau percobaan. Penelitian ini menggunakan rancangan Penelitian Tindakan Kelas (PTK) dimana terdapat 2 siklus dengan masing-masing tahapan yaitu perencanaan, pelaksanaan, pengamatan, dan refleksi. Hasil penelitian ini adalah: (1) Motivasi belajar siswa sebelum tindakan mempunyai persentase ketuntasan sebesar 46,10%, pada siklus 1 adalah 68,75% dan pada siklus 2 sebesar 100%. (2) Hasil belajar pengetahuan siswa sebelum tindakan sebesar 53,12% dengan nilai rata-rata 71,56, kemudian pada siklus 1 sebesar 81,25% dengan nilai rata-rata 75,78, dan pada siklus 2 sebesar 100% dengan nilai rata-rata 82,03. (3) Hasil belajar sikap pada siklus 1 mempunyai persentase sebesar 77,86% dan pada siklus 2 adalah 85,41%. (4) Hasil belajar keterampilan pada siklus 1 mempunyai presentase sebesar 77,34% dan pada  siklus 2 adalah 89,84%. Kesimpulan dari hasil penelitian kelas X TKJ 1 pada mata pelajaran Pemrograman Dasar dengan penerapan model Discovery Learning mampu meningkatkan motivasi belajar siswa, hasil belajar pengetahuan, hasil belajar sikap dan hasil belajar keterampilan

Achillea millefolium: Mechanism of action, pharmacokinetic, clinical drug-drug interactions and tolerability

Background: Achillea millefolium, known as Yarrow, is a medicinal plant in the Asteraceae family which is one of the oldest known botanicals used by humans and itis one of the most important medicinal plants in the pharmaceutical field. Purpose: This review discusses pharmacodynamics, pharmacokinetics, and mechanism of action of the most important component of Achillea millefolium. There are a variety of same species such as white, red and yellow yarrow and all of these species have been discussed in this manuscript. We focus on previously discovered hormonal, antibiotic, and anticancer drug interactions with Achillea millefolium that may decrease or increase the concentration of certain drugs. We categorized different interactions of this herb into minor and serious ones, such as affecting Cytochromes P450 metabolism enzyme, resulting in a concentration rise in drugs such as Erythromycin, Diazepam, and Cyclosporine.The reason of writing a review article in this field is our enthusiasm for pharmacology of herbal ingredients and also, we want to gather other scientists’ and our knowledge in this review for future researchers who like to know more about this plant pharmacological criteria in order to make their way. Method: Pharmacological and phytochemical-specific details of Achillea millefolium, as well as related keywords, were used to conduct a literature search across the following essential collections of electronic databases: Web of Science, Google Scholar, PubMed, and Science Direct. Outcome: Achillea millefolium medical indications are the treatment of spasmodic gastrointestinal ulcers, inflammation, wound healing, and cancers, as well as excellent antioxidant activity. Camphene, Limonene, Apigenin and some other components show anti-inflammatory effects by cyclooxygenase inhibition, prostaglandin E2 inhibition and other mechanisms. Studies showed 90 % of its essential oil consists of monoterpenes which can be mutually beneficial with extract components. Conclusion: A. millefolium can play a significant role as a strong antioxidant and anticancer source, positively affecting gastrointestinal inflammations