Spontaneous symmetry breaking in amnestically induced persistence

We investigate a recently proposed non-Markovian random walk model characterized by loss of memories of the recent past and amnestically induced persistence. We report numerical and analytical results showing the complete phase diagram, consisting of 4 phases, for this system: (i) classical nonpersistence, (ii) classical persistence (iii) log-periodic nonpersistence and (iv) log-periodic persistence driven by negative feedback. The first two phases possess continuous scale invariance symmetry, however log-periodicity breaks this symmetry. Instead, log-periodic motion satisfies discrete scale invariance symmetry, with complex rather than real fractal dimensions. We find for log-periodic persistence evidence not only of statistical but also of geometric self-similarity.Comment: 4 pages, 2 color fig

A contribuição do município de Guarulhos (estado de São Paulo) para a qualidade da água no Sistema Alto Tietê

The population growth in Guarulhos (São Paulo State) has been above the average for the São Paulo Metropolitan Region (RMSP). The Baquirivu-Guaçu River Basin (BHRBG), where the Baquirivu-Guaçu River is located, is exactly the urban expansion vector of Guarulhos municipality and neighboring areas. This study presents an analysis of the quality of the Baquirivu-Guaçu River waters at the entrance and at the exit of the Guarulhos municipality, in order to assess the effects of the implementation of sewage treatment plants (STPs) and land use on the Baquirivu-Guaçu River water quality between 2010 and 2014. For that were prepared the land use maps in the period analyzed, an analysis of the functioning of STPs in the study area, a statistical analysis of the Water Quality Index (WQI) and its parameters at different points of the river. The data relative to the Baquirivu-Guaçu River physico-chemicals and microbiological analyses indicate a much lower water quality in the exit of the Guarulhos municipality (WQI=16), when compared to that coming from the Arujá municipality (WQI=32). The mean values highlighted for BOD, DO, TU, TS and FC parameters indicate a considerable worsening of the Baquirivu-Guaçu River waters at point BQGU 03850. The values of TN, TP and pH parameters both at the entrance and exit of the basin are close. The analysis of land use evolution and water quality shows the consequences of an improper process of urban growth in the basin and that the domestic and industrial polluting sources represent considerable risk to water quality, attesting that the sanitation works carried out up to now have not been effective in reducing the polluting charges launched in the Baquirivu-Guaçu River waters.A contribuição do município de Guarulhos (Estado de São Paulo) para a qualidade de água do Sistema Alto Tietê. Guarulhos (SP) tem apresentado índices de crescimento populacional acima da média da Região Metropolitana de São Paulo (RMSP). A Bacia Hidrográfica do Rio Baquirivu Guaçu (BHRBG), onde se localiza o Rio Baquirivu Guaçu, é o vetor de expansão urbana do município e da região. Este trabalho apresenta uma análise da qualidade das águas do Rio Baquirivu-Guaçu na entrada e na saída do município de Guarulhos, avaliando os efeitos da implantação das ETEs e do uso da terra sobre a qualidade das águas do Rio Baquirivu-Guaçu, entre os anos de 2010 e 2014. Para isto foram elaborados os mapas de uso de terra no período analisado, uma análise do funcionamento das ETEs na área de estudo, e a análise estatística dos Índices de Qualidade de Águas (IQA) e de seus parâmetros nos diferentes pontos do rio. Os dados referentes às análises físico-química e microbiológica do Rio Baquirivu-Guaçu indicam uma qualidade de água na saída do município de Guarulhos (IQA=16), muito inferior àquela que recebe do município de Arujá (IQA=32). Os valores médios, em especial para os parâmetros DBO, OD, TU, ST e CF indicam uma piora na qualidade das águas do Rio Baquirivu-Guaçu no ponto BQGU03850. Os valores dos parâmetros NT, PT e pH foram muito próximos para ambos os pontos da entrada e saída da bacia. A análise entre a evolução do uso da terra e a qualidade da água demonstra as consequências do processo inadequado de crescimento urbano na bacia e que as fontes poluidoras domésticas e industriais representam considerável risco à qualidade das águas, demonstrando que as obras de saneamento realizadas até o momento não foram eficazes na redução de cargas poluidoras das águas do rio Baquirivu-Guaçu

PVM-based intelligent predictive control of HVAC systems

This paper describes the application of a complete MBPC solution for existing HVAC systems, with a focus on the implementation of the objective function employed. Real-time results obtained with this solution, in terms of economical savings and thermal comfort, are compared with standard, temperature regulated control.(1) (C) 2016, IFAC (International Federation of Antomatic Control) Hosting by Elsevier Ltd. All rights reserved

Surface tension implementation for Gensmac 2D

In the present work we describe a method which allows the incorporation of surface tension into the GENSMAC2D code. This is achieved on two scales. First on the scale of a cell, the surface tension effects are incorporated into the free surface boundary conditions through the computation of the capillary pressure. The required curvature is estimated by fitting a least square circle to the free surface using the tracking particles in the cell and in its close neighbors. On a sub-cell scale, short wavelength perturbations are filtered out using a local 4-point stencil which is mass conservative. An efficient implementation is obtained through a dual representation of the cell data, using both a matrix representation, for ease at identifying neighbouring cells, and also a tree data structure, which permits the representation of specific groups of cells with additional information pertaining to that group. The resulting code is shown to be robust, and to produce accurate results when compared with exact solutions of selected fluid dynamic problems involving surface tension

Clustering of comb and propolis waxes based on the distribution of aliphatic constituents

Chemical composition data for 41 samples of propolis waxes and 9 samples of comb waxes of Apis mellifera collected mainly in Brazil were treated using Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA). For chemometrical analysis, the distribution of hydrocarbons and residues of alcohols and carboxylic acids of monoesters were considered. The clustering obtained revealed chemical affinities and differences not previously grasped by simple eye-inspection of the data. No consistent differences were detected between comb and propolis waxes. These and previous results suggest that hydrocarbons, carboxylic acids, aliphatic alcohols and esters from both comb and propolis waxes are bee-produced compounds and, hence, the differences detected between one and another region are dependent on genetic factors related to the insects rather than the local flora. The samples analyzed were split into two main clusters, one of them comprising exclusively material collected in the State of São Paulo. The results are discussed with respect to the africanization of honeybees that first took place in that State and therefrom irradiated to other parts of Brazil.Os resultados obtidos com a análise química de 41 amostras de ceras de própolis e 9 amostras de ceras de favos de Apis mellifera, coletadas principalmente no Brasil, foram estudados usando Análise de Componentes Principais e Análise Hierárquica de Grupos. Na análise quimiométrica foram consideradas a distribuição de hidrocarbonetos e de resíduos alcoólicos e ácidos de mono-ésteres. O dendrograma obtido revelou afinidades químicas e diferenças que não puderam ser constatadas com a simples inspeção visual dos dados. Nenhuma diferença consistente foi detectada entre ceras de própolis e de favos. Os resultados deste e de outros trabalhos sugerem que hidrocarbonetos, ácidos carboxílicos, álcoois alifáticos e ésteres das ceras de própolis e de favos são produzidos pelas abelhas e, portanto, as diferenças detectadas entre uma e outra região são mais dependentes de fatores genéticos relacionados aos insetos do que da flora local. As amostras analisadas reuniram-se segundo dois grandes agrupamentos, um deles contendo exclusivamente amostras coletadas no Estado de São Paulo. Os resultados são discutidos levando em consideração o fato de que a africanização das abelhas teve início nesse estado, ocorrendo posteriormente a sua irradiação para outras partes do Brasil.354357Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

The Expression of NTAL and Its Protein Interactors Is Associated With Clinical Outcomes in Acute Myeloid Leukemia

Non–T cell activation linker (NTAL) membrane protein depletion from lipid rafts by alkylphospholipids or downregulation by shRNA knockdown decreases cell viability through regulation of the Akt/PI3K pathway in mantle cell lymphoma and acute promyelocytic leukemia cells. Here, we confirmed that the knockdown of NTAL in acute myeloid leukemia (AML) cell lines was associated with decreased cell proliferation and survival. Similarly, a xenograft model using AML cells transduced with NTAL–shRNA and transplanted into immunodeficient mice led to a 1.8-fold decrease in tumor burden. Using immunoprecipitation, LC–MS/MS analysis, and label-free protein quantification, we identified interactors of NTAL in two AML cell lines. By evaluating the gene expression signatures of the NTAL protein interactors using the PREdiction of Clinical Outcomes from Genomic Profiles database, we found that 12 NTAL interactors could predict overall survival in AML, in at least two independent cohorts. In addition, patients with AML exhibiting a high expression of NTAL and its interactors were associated with a leukemic granulocyte–macrophage progenitor–like state. Taken together, our data provide evidence that NTAL and its protein interactors are relevant to AML cell proliferation and survival and represent potential therapeutic targets for granulocyte–macrophage progenitor–like leukemias

EFEITO DA IDADE FISIOLÓGICA DE SEMENTES DE SOJA NOS RESULTADOS DO TESTE DE ENVELHECIMENTO ACELERADO.

With the objective to study the effect of the fisiologic age of soybean seeds in the results of the test of accelerated aging, it was lead en the laboratory of the Department of Fitotecnia of FCAVJ/ UNESP, an experiment with soybean seeds, CV. IAC 8 proceeding from harvests 1992/93, 93/94 and 94/95. Five periods has been used of stress (36, 48, 60, 72 and 84 hours). The analysed variables had been percentage of germination in the fifth day and the index of emergency speed. A complete randomized experimental design, with a factorial arrangement, was used. For the seeds of harvest 1992/93, that initially they presented germination of 68%, the aging after 48 hours was enough to reduce in 58% its germination. For harvests 93/94 and 94/95, with initial germination of 96 and 98,5%, respectively, the time of aging to reduce in 50% the germination was not detected, with up to 84 hours of estresse. The results indicate that the period of aging to be used in soybeans, must consider the initial quality of the seeds.Com o objetivo de estudar o efeito da idade fisiológica de sementes de soja nos resultados do teste de envelhecimento acelerado, foi conduzido no laboratório de sementes do Departamento de Fitotecnia da FCAVJ/UNESP, um experimento com sementes de soja da cultivar IAC 8 provenientes das safras 1992/93, 93/94 e 94/95. Foram utilizados cinco períodos de estresse (36, 48, 60, 72 e 84 horas). As variáveis analisadas foram primeira contagem da germinação, no quinto dia e o índice de velocidade de emergência. O delineamento experimental utilizado foi o inteiramente casualizado em um arranjo fatorial. Para as sementes da safra 1992/93, que inicialmente apresentavam germinação de 68%, o envelhecimento após 48 horas a 42º C, foi suficiente para reduzir para 58% a sua germinação. Para as safras 93/94 e 94/95, com germinação inicial de 96 e 98,5% respectivamente, o tempo de envelhecimento para reduzir em 50% a germinação não foi detectado, com até 84 horas de estresse. Os resultados indicam que o período de envelhecimento a ser usado em sementes de soja, deve considerar a qualidade inicial das sementes

Graphene growth on h-BN by Molecular Beam Epitaxy

The growth of single layer graphene nanometer size domains by solid carbon source molecular beam epitaxy on hexagonal boron nitride (h-BN) flakes is demonstrated. Formation of single-layer graphene is clearly apparent in Raman spectra which display sharp optical phonon bands. Atomic-force microscope images and Raman maps reveal that the graphene grown depends on the surface morphology of the h-BN substrates. The growth is governed by the high mobility of the carbon atoms on the h-BN surface, in a manner that is consistent with van der Waals epitaxy. The successful growth of graphene layers depends on the substrate temperature, but is independent of the incident flux of carbon atoms.Comment: Solid State Communications, 201