Analisis Penggunaan Pasir Pantai Sampur Sebagai Agregat Halus Terhadap Kuat Tekan Beton

Penelitian tentang pemanfaatan pasir pantai sebagai agregat halus dalam pembuatanbeton ini dilatarbelakangi oleh ketersediaan pasir pantai di alam dalam jumlah yangsangat besar. Pasir pantai yang digunakan berasal dari daerah Pantai Sampur, kotaPangkalpinang. Penelitian ini bertujuan untuk mengetahui seberapa besar kuat tekanbeton yang dihasilkan ketika menggunakan beberapa perlakuan terhadap pasir pantaiSampur. Perlakuan yang digunakan terhadap pasir Pantai Sampur adalah : tanpaperlakuan, disiram, dan dicuci. Kuat tekan beton direncanakan 17,5 MPa. Sampelberbentuk silinder dan berjumlah 24 buah. Penelitian ini juga menggunakan beton normaldari pasir yang berbeda sebagai kontrol, yaitu pasir daerah Padang Baru KabupatenBangka Tengah. Campuran beton dengan pasir Padang Baru (beton normal)menghasilkan kuat tekan rata-rata sebesar 28,68 MPa. Sedangkan kuat tekan beton rata-rata pada pasir pantai Sampur tanpa perlakuan sebesar 16,36 MPa, dengan perlakuandisiram sebesar 17,52 MPa dan dengan perlakuan dicuci sebesar 22,14 Mpa. Kuat tekanbeton terbesar pasir Pantai Sampur terletak pada perlakuan dicuci yaitu sebesar 22,14Mpa.Kata kunci : pasir pantai, kuat tekan beto

Peningkatan Keterampilan Menulis Karya Ilmiah Bagi Guru Sekolah Dasar di Kota Semarang

PENINGKATAN KETERAMPILAN MENULIS KARYA ILMIAH BAGI GURU SEKOLAH DASAR DI KOTA SEMARAN

Pemberdayaan Remaja Desa Wisata Bendosari Kecamatan Plantungan Kabupaten Kendal melalui Pelatihan Pembuatan Papan Informasi Berbahasa Inggris dan Indonesia

Teenagers have an important role to develop the village into a tourist village. One of the roles is to develop existing facilities and infrastructure at tourist sites. Information boards are a very important part of tourism villages\u27s management because it can be the information about tourist attractions, restrictions and warnings. Therefore, training and mentoring in making information boards in English and Indonesian need to be done in Bendosari Village, Plantungan District, Kendal Regency because of the limited number of information boards at tourist sites, especially in Jeglong Waterfall. The method used in the training is lecture, question and answer and practice. Participants in the training and mentoring activities for the making of this information board were the teenagers of Bendosari Village. The outcomes generated from these training activities are 1) teenagers \u27understanding of the importance of information boards at tourist sites increases, 2) teenagers\u27 understanding of the phrases used on information boards both in English and in Indonesian also increases, 3) models of information boards for tourist sites are created, and 4) nformation boards in English and Indonesian language for tourist sites are created as wel

Implementasi Algoritma Caesar, Cipher Disk, Dan Scytale Pada Aplikasi Enkripsi Dan Dekripsi Pesan Singkat, Lumasms

Short Message Service (SMS) merupakan salah satu cara berkomunikasi yangbanyak digunakan oleh pengguna telepon seluler. Namun banyaknyapengguna telepon seluler yang menggunakan layanan SMS, tidak diimbangidengan faktor keamanan yang ada pada layanan tersebut. Banyak penggunatelepon seluler yang belum menyadari bahwa SMS tidak menjamin integritasdan keamanan pesan yang disampaikan. Ada beberapa risiko yang dapatmengancam keamanan pesan pada layanan SMS, diantaranya: SMS spoofing,SMS snooping, dan SMS interception. Untuk mengurangi risiko tersebut, makadibutuhkan sebuah sistem keamanan pada layanan SMS yang mampu menjagaintegritas dan keamanan isi pesan. Dimana tujuannya ialah untuk menutupicelah pada tingkat keamanan SMS. Salah satu penanggulangannya ialahdengan menerapkan algoritma kriptografi, yaitu kombinasi atas algoritmaCipher Disk, Caesar, dan Scytale pada pesan yang akan dikirim. Tujuan daripenulisan ini adalah membangun aplikasi LumaSMS, dengan menggunakankombinasi ketiga algoritma kriptografi tersebut. Dengan adanya aplikasi inidiharapkan mampu mengurangi masalah keamanan dan integritas SMS

PENGEMBANGAN INSTRUMEN LAGRANGIAN GPS DRIFTER COMBINED (GERNED) UNTUK OBSERVASI LAUT

Instrumen Lagrangian telah banyak digunakan untuk pengumpulan data arus laut dan observasi di perairan Indonesia membutuhkan data yang langsung dapat diketahui (real time). Kajian ini menekankan pada pengembangan GPS Drifter Combined (GERNED) dari sisi desain dan sistem pengukuran. Hasil pengujian menunjukkan bahwa GERNED dapat digunakan di danau, perairan dangkal, dan laut terbuka. Konstruksi terdiri dari bahan akrilik, Polyethylene, dan aluminium. Desain konstruksi terdiri dari bagian atas sebagai penutup dan juga tempat sensor udara dan lampu indikator, bagian tengah yang merupakan pusat mikro-kontroller, catu daya, sensor-sensor, penyimpanan data manual dan pengiriman data via satelit. Biaya yang dibutuhkan untuk membuat alat ini sekitar 15.000.000 (lima belas juta rupiah) dengan biaya terbesar adalah kontrol pengiriman data. Pada bagian bawah merupakan baling-baling statik. Pengujian yang dilakukan di laboratorium untuk melihat posisi lokasi sudah menunjukkan data yang sama dengan data lapangan sedangkan untuk pengujian lapangan yang dilakukan di pulau Untung Jawa menunjukkan bahwa arah dan pergerakan GERNED sama dengan pergerakan float tracking umumnya

Direct Binding of a Hepatitis C Virus Inhibitor to the Viral Capsid Protein

Over 130 million people are infected chronically with hepatitis C virus (HCV), which, together with HBV, is the leading cause of liver disease. Novel small molecule inhibitors of Hepatitis C virus (HCV) are needed to complement or replace current treatments based on pegylated interferon and ribavirin, which are only partially successful and plagued with side-effects. Assembly of the virion is initiated by the oligomerization of core, the capsid protein, followed by the interaction with NS5A and other HCV proteins. By screening for inhibitors of core dimerization, we previously discovered peptides and drug-like compounds that disrupt interactions between core and other HCV proteins, NS3 and NS5A, and block HCV production. Here we report that a biotinylated derivative of SL209, a prototype small molecule inhibitor of core dimerization (IC50 of 2.80 µM) that inhibits HCV production with an EC50 of 3.20 µM, is capable of penetrating HCV-infected cells and tracking with core. Interaction between the inhibitors, core and other viral proteins was demonstrated by SL209–mediated affinity-isolation of HCV proteins from lysates of infected cells, or of the corresponding recombinant HCV proteins. SL209-like inhibitors of HCV core may form the basis of novel treatments of Hepatitis C in combination with other target-specific HCV drugs such as inhibitors of the NS3 protease, the NS5B polymerase, or the NS5A regulatory protein. More generally, our work supports the hypothesis that inhibitors of viral capsid formation might constitute a new class of potent antiviral agents, as was recently also shown for HIV capsid inhibitors

Altering the Motivational Function of Nicotine through Conditioning Processes

The collection of chapters in this 55th Nebraska Symposium on Motivation Volume clearly highlights that effective strategies for reducing compulsive tobacco use will require a multifaceted approach in which genetic, neurobiological, individual, and cultural factors are considered. It is difficult, if not impossible, to predict where the next important breakthrough will come from (Bevins & Bardo, 2004; Dethier, 1966; Laidler, 1998). Accordingly, further research that extends and challenges current theory and practice at each of these levels of analysis is needed. The continuing focus of our research program, and the topic of the present chapter, is on the role of Pavlovian conditioning processes involving nicotine. Theoretical and empirical approaches to nicotine dependence that include Pavlovian conditioning processes have lead to important advances in our understanding and treatment of chronic tobacco use (e.g., see Rose, Chapter 8 and Tiffany, Warthen, & Goedecker, Chapter 10 in current Volume). These approaches conceptualize the drug as an unconditioned stimulus (US) or reinforcer. That is, the pharmacological effects of the drug (e.g., reward, analgesia, psychomotor stimulation) enter into an association with stimuli that reliably co-occur with these effects (e.g., paraphernalia, situational cues). Later exposure to these conditioned stimuli (CSs) can evoke conditioned responses (CRs) that increase the chances an individual will seek drug. More recently, we have suggested that the interoceptive stimulus effects of nicotine might also serve as a CS for other appetitive non-drug outcomes (i.e., USs) and/or a stimulus that occasions whether other CS-US associations will or will not occur (i.e., an occasion setter or facilitator; see Bevins & Palmatier, 2004). We have further suggested that such an associative learning history could impact the tenacity of nicotine addiction—e.g., shorten the time between experimentation and dependence, increase the difficulty of quitting, make sustaining abstinence more difficult, etc. At the current time these suggestions are speculative. With this in mind, the present chapter will review the research in this area, as well as highlight some of its historical precursors and suggest some possible future directions for research. In doing so, hopefully the reader will gain an appreciation for how this approach might lead to further insight into how Pavlovian conditioning processes can alter the motivational function of nicotine in a manner that contributes to chronic tobacco use