50 research outputs found

    Financial Assessment of Construction Company's Performance

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    Předmětem diplomové práce je posouzení finančního zdraví a finanční výkonnosti stavebního podniku. Teoretická část práce je zaměřena na vymezení pojmů výkonnost a finanční zdraví podniku, účetní výkazy a na představení metod finanční analýzy. Praktická část je zaměřena na aplikaci vybraných metod finanční analýzy na konkrétní stavební podnik. Na základě výsledků analýzy je zhodnocena celková finanční situace podniku a sestaven model pro průběžné posuzování výkonnosti a finančního zdraví.The subject of this thesis is evaluation of financial health and financial performance of construction company. Theoretical part of this thesis defines the concept of financial performance, financial health of the company, accounting sheets and explains methods of financial analysis. Practical part focuses on application of chosen methods of financial analysis to specific construction company. Based on the results of analysis the evaluation of financial situation is conducted and model for continuous evaluation of financial performance and financial health is created.

    Commented translation: Turquie de l'ouest et mer Noire (Astrid Lorber, Hachette, Paris 2004, pp. 12-31)

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    Eva Doležalová Univerzita Karlova, Filozofická fakulta Ústav translatologie 2015 ABSTRAKT Tato bakalářská práce se skládá ze dvou částí - překladu francouzského textu do češtiny a jeho komentáře. Překládaným textem je část turistického průvodce Turquie de l'ouest et mer Noire, konkrétně oddíly věnující se turecké společnosti, politice, náboženství a ekonomice. Průvodce vyšel ve francouzském nakladatelství Hachette v edici Guides Bleus Évasion a jeho autorem je cestovatelka Astrid Lorberová. Komentář se nejprve věnuje analýze výchozího textu a poté je představena metoda překladu a typologie překladatelských problémů. KLÍČOVÁ SLOVA komentovaný překlad, překladatelská analýza, překladatelské problémy, překladatelské postupy, turistický průvodce, TureckoEva Doležalová Univerzita Karlova, Filozofická fakulta Ústav translatologie 2015 ABSTRACT This bachelor thesis consists of two parts - translation of a French text into Czech and its commentary. The translated text is a part of the travel guide Turquie de l'ouest et mer Noire, specifically sections about Turkish society, politics, religion and economy. The travel guide was published by French Publisher Hachette in edition Guides Bleus Évasion and was written by traveller Astrid Lorber. The first part of the commentary is an analysis of the source text, the second part presents the method of translation and the typology of translation problems. KEY WORDS commented translation, translation analysis, translation problems, translation methods, travel guide, TurkeyInstitute of Translation StudiesÚstav translatologieFilozofická fakultaFaculty of Art

    Mechanism of rigid overlaying of carboniferous strata failure in face mining in the case of a multiseams deposit

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    The technique of assessing the failure of rigid overlying strata is applicable to deep mining with thick coal seams (a thickness of more than 1 m in the Ostrava–Karvina Coalfield), and in one case to longwall mining with controlled caving. The assessment of failure of rigid overlying strata makes it possible to distinguish whether the rigid overlying strata of rocks has been deformed or whether a strutting arch has been formed over the goaf below which is an area that is free from stress. Good knowledge of the mining, technical and geological conditions of a given site is a prerequisite for successful evaluation. There are advantages to utilising surface measurements for interpreting the effects of changes in rock mass, especially in areas of high overlying strata. The practical importance of failure assessment of overlying strata consists in determining the size of the mined-out area where the deformation of the rigid overlying strata occurred, which is dependent on the character of the rock mass. This paper is set in the context of the expected width of the goaf during deformation of rigid overlying strata within parameters that describe the mining and geological conditions of the locality. Changes in the area of the goaf, based the results of tensometric measurements, will also be placed in context.Web of Science10219518

    Variation in Egg Yolk Colour in Different Systems of Rearing Laying Hens

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    A total of 72 laying hens (ISA BROWN hybrid combination) were divided into two groups. Thirty-six layers in the first group were reared on litter while the second group of layers was reared using the cage rearing system. Samples of eggs were collected from both groups for a period of seven months. Yolk colour was determined using a portable spectrophotometer using a newly developed method, which complied with the CIELAB system. Yolk colour indicator L* decreased for the rearing system on litter, i.e. egg yolk colour became darker in the course of the whole experiment (α = 0.05). Indicator a* showed a distinct increase in the case of the rearing system on litter, with the differences being significant (α = 0.05) over the last three months of the experiment. Differences for the whole experiment were highly conclusive (α = 0.01), as seen from the increasing red colour intensity. Similarly, indicator b* also increased, i.e. egg yolk was of more distinct yellow colour. In the case of the cage-rearing system, egg yolk colour indicators correlated well with egg weight indicators, as compared to the rearing system on litter. The rearing system on litter resulted in significantly increased intensity of orange colour compared to the cage rearing system

    Genetic variability and distance between Lactuca serriola L. populations from Sweden and Slovenia assessed by SSR and AFLP markers - Online supplement

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    The study involved 121 samples of the common weed, Lactuca serriola L. (prickly lettuce), representing 53 populations from Sweden and Slovenia. The seed materials, originating from different habitats, were regenerated and taxonomically validated at the Department of Botany, Palacký University in Olomouc, Czech Republic. The morphological characterizations of the collected plant materials classified all 121 samples as L. serriola f. serriola; one sample was heterogeneous, and also present was L. serriola f. integrifolia. Differences in the amount and distribution of the genetic variations between the two regions were analyzed using 257 amplified fragment length polymorphism (AFLP) and 7 microsatellite (SSRs) markers. Bayesian clustering and Neighbor- Network were used for visualization of the differences among the samples by country. Under the Bayesian approach, the best partitioning (according to the most frequent signals) was resolved into three groups. While the absence of an admixture or low admixture was detected in the Slovenian samples, and the majority of the Swedish samples, a significant admixture was detected in the profiles of five Swedish samples collected near Malmö, which bore unique morphological features of their rosette leaves. The Neighbor-Network analysis divided the samples into 6 groups, each consisting of samples coming from a particular country. Reflection of morphology and eco-geographical conditions in genetic variation are also discussed

    Genetic variability and distance between Lactuca serriola L. populations from Sweden and Slovenia assessed by SSR and AFLP markers

    Get PDF
    The study involved 121 samples of the common weed, Lactuca serriola L. (prickly lettuce), representing 53 populations from Sweden and Slovenia. The seed materials, originating from different habitats, were regenerated and taxonomically validated at the Department of Botany, Palacký University in Olomouc, Czech Republic. The morphological characterizations of the collected plant materials classified all 121 samples as L. serriola f. serriola; one sample was heterogeneous, and also present was L. serriola f. integrifolia. Differences in the amount and distribution of the genetic variations between the two regions were analyzed using 257 amplified fragment length polymorphism (AFLP) and 7 microsatellite (SSRs) markers. Bayesian clustering and Neighbor- Network were used for visualization of the differences among the samples by country. Under the Bayesian approach, the best partitioning (according to the most frequent signals) was resolved into three groups. While the absence of an admixture or low admixture was detected in the Slovenian samples, and the majority of the Swedish samples, a significant admixture was detected in the profiles of five Swedish samples collected near Malmö, which bore unique morphological features of their rosette leaves. The Neighbor-Network analysis divided the samples into 6 groups, each consisting of samples coming from a particular country. Reflection of morphology and eco-geographical conditions in genetic variation are also discussed

    Muckle-Wells Syndrome Across Four Generations in One Czech Family: Natural Course of the Disease

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    Background: Muckle-Wells syndrome (MWS) represents a moderate phenotype of cryopyrinopathies. Sensorineural hearing loss and AA amyloidosis belong to the most severe manifestations of uncontrolled disease. Simultaneous discovery of MWS in four generations of one large kindred has enabled us to document natural evolution of untreated disease and their response to targeted therapy.Methods: A retrospective case study, clinical assessment at the time of diagnosis and 2-year prospective follow-up using standardized disease assessments were combined.Results: Collaborative effort of primary care physicians and pediatric and adult specialists led to identification of 11 individuals with MWS within one family. Presence of p.Ala441Val mutation was confirmed. The mildest phenotype of young children suffering with recurrent rash surprised by normal blood tests and absence of fevers. Young adults all presented with fevers, rash, conjunctivitis, and arthralgia/arthritis with raised inflammatory markers. Two patients aged over 50 years suffered with hearing loss and AA amyloidosis. IL-1 blockade induced disease remission in all individuals while hearing mildly improved or remained stable in affected patients as did renal function in one surviving individual with amyloidosis.Conclusions: We have shown that severity of MWS symptoms gradually increased with age toward distinct generation-specific phenotypes. A uniform trajectory of disease evolution has encouraged us to postpone institution of IL-1 blockade in affected oligosymptomatic children. This report illustrates importance of close interdisciplinary collaboration

    How many species of whipworms do we share? Whipworms from man and other primates form two phylogenetic lineages

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    The whipworms, i.e. parasitic nematodes of the genus Trichuris Roederer, 1761, infect a variety of mammals. Apparently low diversity of primate-infecting species of Trichuris strongly contrasts with the high number of species described in other mammalian hosts. The present study addresses the diversity of whipworms in captive and free-ranging primates and humans by analysing nuclear (18S rRNA, ITS2) and mitochondrial (cox1) DNA. Phylogenetic analyses revealed that primate whipworms form two independent lineages: (i) the Trichuris trichiura (Linnaeus, 1771) clade comprised of genetically almost identical whipworms from human and other primates, which suggests the ability of T. trichiura to infect a broader range of primates; (ii) a clade containing primarily Trichuris suis Schrank, 1788, where isolates from human and various primates formed a sister group to isolates from pigs; the former isolates thus may represent of more species of Trichuris in primates including humans. The analysis of cox1 has shown the polyphyly of the genera Trichuris and Capillaria, Zeder, 1800. High sequence similarity of the T. trichiura isolates from humans and other primates suggests their zoonotic potential, although the extent of transmission between human and other non‐human primates remains questionable and requires further stud

    A Novel Statistical Model for Predicting the Efficacy of Vagal Nerve Stimulation in Patients With Epilepsy (Pre-X-Stim) Is Applicable to Different EEG Systems

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    Background: Identifying patients with intractable epilepsy who would benefit from therapeutic chronic vagal nerve stimulation (VNS) preoperatively remains a major clinical challenge. We have developed a statistical model for predicting VNS efficacy using only routine preimplantation electroencephalogram (EEG) recorded with the TruScan EEG device (Brazdil et al., 2019). It remains to be seen, however, if this model can be applied in different clinical settings. Objective: To validate our model using EEG data acquired with a different recording system. Methods: We identified a validation cohort of eight patients implanted with VNS, whose preimplantation EEG was recorded on the BrainScope device and who underwent the EEG recording according to the protocol. The classifier developed in our earlier work, named Pre-X-Stim, was then employed to classify these patients as predicted responders or non-responders based on the dynamics in EEG power spectra. Predicted and real-world outcomes were compared to establish the applicability of this classifier. In total, two validation experiments were performed using two different validation approaches (single classifier or classifier voting). Results: The classifier achieved 75% accuracy, 67% sensitivity, and 100% specificity. Only two patients, both real-life responders, were classified incorrectly in both validation experiments. Conclusion: We have validated the Pre-X-Stim model on EEGs from a different recording system, which indicates its application under different technical conditions. Our approach, based on preoperative EEG, is easily applied and financially undemanding and presents great potential for real-world clinical use

    Research gaps and challenges in the conservation and use of North American wild lettuce germplasm

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    The North American crop wild relatives (CWR) of lettuce (Lactuca L.) represent an underexplored pool of genetic diversity of potential value to breeding programs. The 10 species belong to three different groups: a native clade including at least six allotetraploid species [L. biennis (Moench) Fernald, L. canadensis L., L. floridana (L.) Gaertn., L. graminifolia Michx., L. hirsuta Muhl. ex Nutt., and L. ludoviciana (Nutt.) Riddell], a diploid clade with one species [L. tatarica (L.) C. A. Mey. subsp. pulchella (Pursh) Stebbins], and a clade related to the cultivated taxon (L. sativa L.) with three non‐native species (L. saligna L., L. serriola L., and L. virosa L.). In this review, we examine the role of herbarium and genebank holdings in taxonomic and other foundational studies, as well as for germplasm exploration and use. We compile the state of knowledge on the ranges of lettuce CWR in North America, modeling the potential distributions of the species and assessing their ex situ and (for native species) in situ conservation status. We categorize seven of the species as high priority for further conservation and three as medium priority, with none currently considered low priority or sufficiently conserved. Further, we review morphological, phenological, genetic diversity, and pest and disease information with regard to North American species. We conclude by outlining the critical gaps and describing a way forward for addressing challenges in the conservation and use of North American wild lettuce germplasm
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