264 research outputs found
"EL SAGRADO CORAZÓN DEL NIÑO JESÚS" APROXIMACIÓN TÉCNICA, DOCUMENTAL Y PROCESO DE INTERVENCIÓN A UNA OBRA INÉDITA DE JOSÉ VERGARA (1726-1799)
[ES] La
o
br
a
o
bj
e
t
o
de
e
s
tudi
o
d
el
pr
e
sen
t
e
T
r
abajo
Fi
n
al
de
Gr
ad
o
e
s
una
pin
tur
a
inédi
t
a
a
tribuid
a
al
pint
or
v
al
encian
o
Jos
é
V
er
g
ar
a
Gim
eno
(1
7
2
6
-
1799).
Ejecut
ada
t
écnic
a
men
t
e
al
óle
o
s
obr
e
lienz
o
y
c
o
n
f
orma
t
o
ov
al,
s
e
encuen
tr
a
r
epre
sen
t
ad
o
u
n
Sa
gr
ad
o
C
o
r
azón
del
Niñ
o
J
esús,
en
virtud
del
cual
se
r
eali
z
ar
on
búsqu
edas
si
s
t
emá
tic
as
d
e
r
e
f
er
en
t
es
,
p
udien
do
c
ompar
ar
c
o
n
o
tr
as
r
epr
esent
a
cione
s
d
e
t
e
má
tic
a
si
milar
d
el
ar
tis
t
a;
e
s
t
o
n
o
s
per
mitió
pr
ofun
diz
ar
en
dif
er
en
t
e
s
asp
ectos,
t
ales
c
o
mo
el
estud
io
t
écnic
o
,
artí
s
tic
o
e
ic
ónic
o, t
an
t
o
d
e
la
obr
a c
o
m
o
del pin
t
o
r
v
alencian
o
.
Po
r
otr
o
lad
o,
las
di
ver
sas
pér
di
das
de
es
tr
a
t
o
s
pict
óric
os
lo
c
ali
z
adas
en
el
mar
gen
in
f
eri
or
qu
e
en
t
or
pecían
la
p
er
ce
p
ci
ó
n
par
ci
al
de
la
o
b
r
a,
n
o
s
h
icier
on
t
omar
la
de
cisión
de
lle
v
ar a
c
ab
o
un
pr
oc
es
o
d
e
in
t
er
v
enci
ó
n, el cual
c
ons
t
a
de
la
subsan
ació
n
de
un
pe
queño
d
esg
arr
o
en
el
m
ar
g
en
in
f
erior
der
e
cho;
t
am
b
ién
del
bas
tid
or
,
n
ot
able
men
t
e
a
t
ac
ad
o
p
or
in
sec
t
o
s
xil
óf
ag
o
s;
la
r
ealiz
ación
d
e
un
en
t
el
ado
,
ad
apt
ado
a
la
morf
olo
g
ía
d
e
la
o
br
a,
y
po
r
ú
ltimo,
c
o
n
el
p
r
oceso
de
es
tuc
ad
o
y
la
r
ein
t
e
g
r
aci
ón
p
ic
t
ó
ri
c
a
que
p
er
m
iti
ó
de
volv
er
la c
o
n
tinuid
ad de l
a
o
b
r
a[EN]
The
sub
ject
o
f
this
Fi
nal
Degr
e
e
Pr
oject
is
an
o
rig
inal
pain
ting
a
t
tribu
t
e
d
t
o
the v
al
encian
pain
t
e
r
Jos
é
V
er
g
ar
a Gi
men
o
(
1726
-
179
9).
T
echnic
al
ly
e
x
ecut
ed
in
oil
o
n
c
an
v
as
and
ov
al
f
o
r
ma
t,
it
r
epr
esent
s
a
Sa
cr
ed
Heart
o
f
Chris
t
Chil
d,
b
y
virtue
o
f
which
usin
g
s
ys
t
ema
tic
sea
r
ch
es
of
r
e
f
er
enc
es
w
e’
r
e
m
ad
e
an
d
c
om
p
ared
with
o
ther
r
ep
r
esent
a
ti
ons
of
similar
them
es
o
f
the
artis
t;
thi
s
a
llow
e
d
us
t
o
del
ve
in
to
d
if
f
er
en
t
aspe
cts,
such
as
a
s
tudy
o
f
the
artis
tic,
ic
o
n
ic
and
t
echnic
al
asp
ects
both
the
w
or
k
an
d
the
V
alencian
pain
t
er
.
On
the
other
han
d,
th
e
v
a
rious
losses
of
pain
t
la
yer
s
loc
a
ted
o
n
the
l
o
w
e
r
edg
e
tha
t
hin
der
ed
the
par
tial
per
c
eptio
n
of
th
e
w
or
k
,
m
ade
us
decide
t
o
c
arry
o
u
t
an
int
er
ven
ti
on
p
r
ocess,
which
c
o
n
sis
ts
o
f
the
c
o
r
r
ecti
on
of
a
small
t
ear
i
n
the
rig
ht
lo
w
er
mar
gin
;
als
o
the
fr
a
me
with
a
no
tice
able
xyl
ophag
o
u
s
a
t
tack
;
the
r
ealiz
a
ti
o
n
o
f
a
scri
m,
ad
ap
t
ed
t
o
th
e
m
o
rp
hol
o
g
y
o
f
th
e
w
or
k,
an
d
a
t
las
t,
a
ma
t
t
eric
and
pict
o
ric
r
e
f
und
which
enabl
ed
t
o
r
e
tu
rn
the
c
o
n
tinuit
y
o
f
th
e
w
o
rk.Pastor Esteve, E. (2016). "EL SAGRADO CORAZÓN DEL NIÑO JESÚS" APROXIMACIÓN TÉCNICA, DOCUMENTAL Y PROCESO DE INTERVENCIÓN A UNA OBRA INÉDITA DE JOSÉ VERGARA (1726-1799). http://hdl.handle.net/10251/74235.TFG
Red de elaboración de materiales en la asignatura de “Teoría y práctica del entrenamiento deportivo”
El objetivo del proyecto cuya memoria se presenta ha consistido en la preparación, diseño y elaboración, de los materiales de la asignatura del tercer curso de Grado “Teoría y práctica del entrenamiento deportivo”. Dichos materiales se utilizarán como documento base el próximo curso 2014/15. Hemos tomando como referencia un sistema basado en el crédito europeo y que supone un cambio radical, no solo a nivel estructural, sino también en relación con las metodologías docentes y la evaluación. En el ámbito del entrenamiento deportivo, el título de “Grado en ciencias de la actividad física y del deporte” distingue cinco asignaturas que abarcan un amplio abanico de contenidos. En su conjunto esta materia posee una gran carga en cuanto a número de créditos dentro del título, por lo que las competencias y contenidos deben definirse claramente. La asignatura “Teoría y práctica del entrenamiento deportivo” se imparte durante el primer cuatrimestre del tercer curso, por lo que es la base de todas las restantes asignaturas del ámbito del entrenamiento deportivo. El trabajo realizado ha tratado de conseguir, en un esfuerzo de coordinación docente, una metodología común adecuada para el desarrollo de los contenidos, la evaluación de los conocimientos y competencias adquiridos en esta asignatura
Lichen sclerosus of the oral mucosa : a case report
Lichen sclerosus or lichen sclerosus et atrophicus is a chronic inflammatory disease predominantly affecting the genital mucosa and skin. Clinically, it is characterized by white atrophic plaques in the anogenital region. The lesions are generally asymptomatic, but may cause discomfort with itching and pain. Extragenital mucosal involvement is very unusual, and lesions limited to the oral mucosa are even less frequent. Knowledge of such lesions is important in order to establish a differential diagnosis with other white oral lesions, and histological confirmation is required. We present the case of a 31-year-old woman with a well delimited, pearly white lesion located in the upper gingival mucosa, lip mucosa and adjacent skin. The lesion had led to loss of periodontal attachment of the affected tooth (2.3), causing pain in response to tooth brushing. The biopsy confirmed lichen sclerosus, and treatment was provided in the form of intralesional corticoid injections, followed by improvement of the mucosal lesion, though without recovery of the periodontal loss
Intra-ventricular thrombus resolution after anticoagulation therapy with rivaroxaban in patient with poor anticoagulation quality
Mecanismos de producción y bases del tratamiento del shock
El shock es la principal causa de muerte en los pacientes ingresados en las unidades de cuidados intensivos, de ahí su importancia en la práctica clínica. En los últimos años se ha realizado diversos estudios que permiten entender mejor las bases fisiopatológicas de la producción del shock y ampliar la estrategia terapéutica hacia el uso de moduladores de la inflamación. En este artículo se revisan los diferentes tipos de shock, con las principales características diferenciales en el comportamiento hemodinámico y en la actitud terapéutica a seguir. Dado que las bases fisiopatológicas del shock han sido mejor estudiadas en el shock séptico, revisaremos con más detalle los mecanismos íntimos de producción de este tipo de shock, así como sus efectos multisistémicos. En cuanto al tratamiento, revisaremos el manejo de la fluidoterapia, los fármacos vasoactivos y los principales moduladores de la inflamación utilizados en el manejo del shock séptico
Bacteremia originating in the oral cavity. A review
In patients at risk because of heart disease, bacteremias induced by invasive dental treatments have been reported as a cause of bacterial endocarditis (BE) - a serious disorder that continues to involve a high mortality. As a result, different scientific societies have supported recommendations for the administration of antibiotics prior to invasive dental treatments, in order to neutralize bacteremia. In this context, the recommendations of the American Heart Association (AHA) are the most widely used in our setting. Advances in our knowledge of the etiopathogenesis of bacterial endocarditis have placed increasingly less importance on invasive dental treatments as a causal factor (the AHA again reduced the number of cases in which antibiotic prophylaxis is recommended, on occasion of its latest guidelines update in 2007) - with increasingly greater importance being placed on factors associated with hygiene and oral health. The present study offers a critical review of the relationship between dental treatment, bacteremia and bacterial endocarditis
Long-Term Stroke Risk Prediction in Patients With Atrial Fibrillation:Comparison of the ABC-Stroke and CHA2DS2-VASc Scores
Background
The
ABC
‐stroke score (age, biomarkers [N‐terminal fragment B‐type natriuretic peptide, high‐sensitivity troponin], and clinical history [prior stroke/transient ischemic attack]) was proposed to predict stroke in atrial fibrillation (
AF
). This score was derived/validated in 2 clinical trial cohorts in which patients with AF were highly selected and carefully followed‐up. However, the median follow‐up was 1.9 years in the trial cohort; therefore, its long‐term predictive performance remains uncertain. This study aimed to compare the long‐term predictive performances of the
ABC
‐stroke and
CHA
2
DS
2
‐
VAS
c (cardiac failure or dysfunction, hypertension, age ≥75 [doubled], diabetes mellitus, stroke [doubled]—vascular disease, age 65 to 74 years and sex category [female]) scores in a cohort of anticoagulated patients with AF.
Methods and Results
We recruited 1125 consecutive patients with AF who were stable on vitamin K antagonists and followed‐up for a median of 6.5 years.
ABC
‐stroke and
CHA
2
DS
2
‐
VAS
c (cardiac failure or dysfunction, hypertension, age ≥75 [doubled], diabetes mellitus, stroke [doubled]—vascular disease, age 65 to 74 years and sex category [female]) scores were calculated and compared. Median
CHA
2
DS
2
‐
VAS
c and
ABC
‐stroke scores were 4 (interquartile range 3–5) and 9.1 (interquartile range 7.3–11.3), respectively. There were 114 ischemic strokes (1.55% per year) at 6.5 years. The C‐index of
ABC
‐stroke at 3.5 years was significantly higher than
CHA
2
DS
2
‐
VAS
c (0.663 versus 0.600,
P
=0.046), but both C‐indexes were nonsignificantly different at 6.5 years. Integrated discrimination improvement showed a small improvement (<2%) in sensitivity at 3.5 and 6.5 years with
ABC
‐stroke. For
ABC
‐stroke, net reclassification improvement was nonsignificantly different at 3.5 years, and showed a negative reclassification at 6.5 years compared with
CHA
2
DS
2
‐
VAS
c. Decision curve analyses did not show a marked improvement in clinical usefulness of the
ABC
‐stroke score over the
CHA
2
DS
2
‐
VAS
c score.
Conclusions
In anticoagulated patients with AF followed‐up over a long‐term period, the novel
ABC
‐stroke score does not offer significantly better predictive performance compared with the
CHA
2
DS
2
‐
VAS
c score.
</jats:sec
Murcia atrial fibrillation project II:protocol for a prospective observational study in patients with atrial fibrillation
Pediatric dental care in a tertiary public hospital. Four years of experience in the Service of Stomatology of Valencia University General Hospital (Valencia, Spain)
A study is made of the experience gained with the Child Oral Care Program (Plan de Atención Dental Infantil, PADI) in the Service of Stomatology of Valencia University General Hospital (Valencia, Spain) after four years in operation (July 2003 - July 2007). Study design: The sample comprised 2626 children between 5-14 years of age, pertaining to department 9 of the Valencian public health system. A clinical history was compiled in each case, a radiological study was made, and a treatment plan was elaborated including fillings, extractions, and control visits. Results: Of the 2626 designated children, 2369 visited our Service - mostly referred from the Preventive Dental Care Units. A total of 5784 fillings were carried out (93.3% with silver amalgam, 5.6% with composites and the rest as provisional fillings). The permanent first molars were the teeth with the largest number of fillings (70.2% of the total). These were followed in order of frequency by the second molars (19.1%). As regards composite resin fillings, most involved the upper central incisors, followed by the upper lateral incisors. A total of 644 extractions were performed, corresponding to 110 permanent teeth and 534 temporary teeth. In the case of the permanent dentition, the first molars were the most commonly removed teeth. In the temporary dentition, the most frequently removed teeth were the second molars. Conclusions: The response of the population to this program has been very good, and reinforces the preventive measures already in place, with the provision of restorative treatments to improve the oral and dental health of the pediatric population, and yielding good results in terms of the program quality indicators. The Service of Stomatology (Valencia University General Hospital) is able to address the demand and offers the public health network integrated and continuous patient care
Anticoagulantes orales directos frente a antagonistas de la vitamina K en pacientes del «mundo real» con fibrilación auricular no valvular: estudio FANTASIIA
Observational study[Abstract] Introduction and objectives: To compare the long-term results of direct oral anticoagulants (DOAC) vs vitamin K antagonists (VKA) in real-world-patients with nonvalvular atrial fibrillation (NVAF) in a nationwide, prospective study.
Methods: The FANTASIIA registry prospectively included outpatients with AF anticoagulated with DOAC or VKA (per protocol, proportion of VKA and DOAC 4:1), consecutively recruited from June 2013 to October 2014 in Spain. The incidence of major events was analyzed and compared according to the anticoagulant treatment received.
Results: A total of 2178 patients were included in the study (mean age 73.8±9.4 years), and 43.8% were women. Of these, 533 (24.5%) received DOAC and 1645 (75.5%) VKA. After a median follow up of 32.4 months, patients receiving DOAC vs those receiving VKA had lower rates of stroke-0.40 (95%CI, 0.17-0.97) vs 1.07 (95%CI,0.79-1.46) patients/y, P=.032-, severe bleedings-2.13 (95%CI, 1.45-3.13) vs 3.28 (95%CI, 2.75-3.93) patients/y; P = .044-, cardiovascular death-1.20 (95%CI, 0.72-1.99) vs 2.45 (95%CI, 2.00-3.00) patients/y; P = .009-, and all-cause death-3.77 (95%CI, 2.83-5.01) vs 5.54 (95%CI, 4.83-6.34) patients/y; P = .016-. In a modified Cox regression model by the Andersen-Gill method for multiple events, hazard ratios for patients receiving DOAC were: 0.42 (0.16-1.07) for stroke; 0.47 (0.20-1.16) for total embolisms; 0.76 (0.50-1.15) for severe bleedings; 0.67 (0.39-1.18) for cardiovascular death; 0.86 (0.62-1.19) for all-cause death, and 0.82 (0.64-1.05) for the combined event consisting of stroke, embolism, severe bleeding, and all-cause death.
Conclusions: Compared with VKA, DOAC is associated with a trend to a lower incidence of all major events, including death, in patients with NVAF in Spain.[Resumen] Introducción y objetivos. Comparar los resultados a largo plazo de los anticoagulantes orales directos (ACOD) frente a los antagonistas de la vitamina K (AVK) en pacientes del mundo real con fibrilación auricular no valvular (FANV) en un estudio nacional prospectivo.
Métodos. El estudio FANTASIIA incluyó consecutivamente a pacientes ambulatorios con FANV anticoagulados con ACOD o AVK desde junio de 2013 hasta octubre de 2014. Se compararon las tasas de eventos según el anticoagulante administrado.
Resultados. Se incluyó a 2.178 pacientes (edad, 73,8 ± 9,4 años; el 43,8% mujeres); de ellos, 533 (24,5%) recibían ACOD y 1.645 (75,5%), AVK. Tras una mediana de seguimiento de 32,4 meses, los pacientes con ACOD tuvieron tasas más bajas de ictus —0,40 (IC95%, 0,17-0,97) frente a 1,07 (IC95%, 0,79-1,46) pacientes/año; p = 0,032—, hemorragias mayores —2,13 (IC95%, 1,45-3,13) frente a 3,28 (IC95%, 2,75-3,93) pacientes/año; p = 0,044—, muerte cardiovascular —1,20 (IC95%, 0,72-1,99) frente a 2,45 (IC95%, 2,00-3,00) pacientes/año; p = 0,009— y muerte total —3,77 (IC95%, 2,83-5,01) frente a 5,54 (IC95%, 4,83-6,34) pacientes/año; p = 0,016—. En el análisis de Cox modificado según el método de Andersen-Gill para datos con múltiples eventos, las razones de riesgos instantáneos para los pacientes con ACOD fueron 0,42 (0,16-1,07) para el ictus; 0,47 (0,20-1,16) para la embolia sistémica en general; 0,76 (0,50-1,15) para las hemorragias mayores; 0,67 (0,39-1,18) para la muerte cardiovascular; 0,86 (0,62-1,19) para la mortalidad total y 0,82 (0,64-1,05) para el combinado de ictus, embolias, hemorragias mayores y muerte.
Conclusiones. El tratamiento con ACOD se asocia con una tendencia a una menor tasa de todos los eventos graves, incluida la mortalidad, en relación con los AVK en pacientes con FANV en España
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