Teaching intervention to enhance HIV infection awareness in a biomedical science degree

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Condom use remains the predominant prophylactic intervention to control rates of human immunodeficiency virus (HIV) infection. However, chemoprophylactic strategies, which involve pre-exposure prophyaxis (PrEP) and post-exposure prophyaxis (PEP), have emerged as appropriate prevention tools to minimise and prevent future infections. Different studies have indicated that PrEP can prevent new HIV infections among men who have sex with men when used daily or event-based, and it is also effective with heterosexuals and people who inject drugs. However, appropriate education is needed as recent reports have observed a decline in adherence to PrEP over time, particularly in young adults, which will impact on the effectiveness of PrEP. Thus, we created a brief educational short intervention (3 hours) to increase the awareness of HIV with second year BMedSci Medical Science (Hons) students at De Montfort University (DMU, UK) in 2016/17 (Peña-Fernández et al., 2017). Briefly, BMedSci students tailored a community-centred intervention programme to reduce HIV infection rates following evidence-based public health methodology. 92% indicated an acquisition of knowledge for preventing HIV transmission and tools to fight this disease. However, BMedSci students also showed a lack of knowledge of preventative measures (PrEP and PEP), routes of transmission and appropriate screening. We implemented a similar teaching strategy with BSc Biomedical Science (BMS) students enrolled in the level 4 module of Basic Microbiology in 2017/18, but limited to two hours: one-hour lecture and one hour workshop in which different HIV prevention strategies were discussed and analysed by students. BMS students were also provided with an overview about the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90:90:90 targets in the UK (2016). In a similar way as with the BMedSci cohort, BMS students showed little awareness about PEP/PrEP, specifically knowledge about what are they/how they work, access and usage. This teaching intervention was well-received by students according to the feedback provided in the final module level feedback. BMS participants (n=27 out of 187 students) indicated that they enjoyed the session and suggested a practical session and the introduction of case studies to enhance the teaching intervention. We are developing a virtual clinical case study on HIV following recent successful experiences in the development and introduction of these novel learning strategies and have performed small modifications in the delivery of this workshop for 2018/19 to increase engagement and interaction. In conclusion, we consider that similar short education interventions that specifically target HIV chemoprophylaxis would be needed in any degree to prevent the decline in adherence to PrEP over time observed in young adults and reduce PEP/PrEP stigma and other barriers which could impede their access

High spatial resolution optical imaging of the multiple T Tauri system LkH{\alpha} 262/LkH{\alpha} 263

We report high spatial resolution i' band imaging of the multiple T Tauri system LkH$\alpha$ 262/LkH$\alpha$ 263 obtained during the first commissioning period of the Adaptive Optics Lucky Imager (AOLI) at the 4.2 m William Herschel Telescope, using its Lucky Imaging mode. AOLI images have provided photometry for each of the two components LkH$\alpha$ 263 A and B (0.41 arcsec separation) and marginal evidence for an unresolved binary or a disc in LkH$\alpha$ 262. The AOLI data combined with previously available and newly obtained optical and infrared imaging show that the three components of LkH$\alpha$ 263 are co-moving, that there is orbital motion in the AB pair, and, remarkably, that LkH$\alpha$ 262-263 is a common proper motion system with less than 1 mas/yr relative motion. We argue that this is a likely five-component gravitationally bounded system. According to BT-settl models the mass of each of the five components is close to 0.4 M$_{\odot}$ and the age is in the range 1-2 Myr. The presence of discs in some of the components offers an interesting opportunity to investigate the formation and evolution of discs in the early stages of multiple very low-mass systems. In particular, we provide tentative evidence that the disc in 263C could be coplanar with the orbit of 263AB.Comment: 11 pages, 7 figures, Accepted 2016 May

Nearby Optical Galaxies: Selection of the Sample and Identification of Groups

In this paper we describe the Nearby Optical Galaxy (NOG) sample, which is a complete, distance-limited ($cz\leq$6000 km/s) and magnitude-limited (B$\leq$14) sample of $\sim$7000 optical galaxies. The sample covers 2/3 (8.27 sr) of the sky ($|b|>20^{\circ}$) and appears to have a good completeness in redshift (98%). We select the sample on the basis of homogenized corrected total blue magnitudes in order to minimize systematic effects in galaxy sampling. We identify the groups in this sample by means of both the hierarchical and the percolation {\it friends of friends} methods. The resulting catalogs of loose groups appear to be similar and are among the largest catalogs of groups presently available. Most of the NOG galaxies ($\sim$60%) are found to be members of galaxy pairs ($\sim$580 pairs for a total of $\sim$15% of objects) or groups with at least three members ($\sim$500 groups for a total of $\sim$45% of objects). About 40% of galaxies are left ungrouped (field galaxies). We illustrate the main features of the NOG galaxy distribution. Compared to previous optical and IRAS galaxy samples, the NOG provides a denser sampling of the galaxy distribution in the nearby universe. Given its large sky coverage, the identification of groups, and its high-density sampling, the NOG is suited for the analysis of the galaxy density field of the nearby universe, especially on small scales.Comment: 47 pages including 6 figures. Accepted for publication in Ap

A Quantitative Evaluation of the Galaxy Component of COSMOS and APM Catalogs

We have carried out an independent quantitative evaluation of the galaxy component of the "COSMOS/UKST Southern Sky Object Catalogue" (SSC) and the "APM/UKST J Catalogue" (APM). Using CCD observations our results corroborate the accuracy of the photometry of both catalogs, which have an overall dispersion of about 0.2 mag in the range 17 <= b_J <= 21.5. The SSC presents externally calibrated galaxy magnitudes that follow a linear relation, while the APM instrumental magnitudes of galaxies, only internally calibrated by the use of stellar profiles, require second-order corrections. The completeness of both catalogs in a general field falls rapidly fainter than b_J = 20.0, being slightly better for APM. The 90% completeness level of the SSC is reached between b_J = 19.5 and 20.0, while for APM this happens between b_J = 20.5 and 21.0. Both SSC and APM are found to be less complete in a galaxy cluster field. Galaxies misclassified as stars in the SSC receive an incorrect magnitude because the stellar ones take saturation into account besides using a different calibration curve. In both cases, the misclassified galaxies show a large diversity of colors that range from typical colors of early-types to those of blue star-forming galaxies. A possible explanation for this effect is that it results from the combination of low sampling resolutions with properties of the image classifier for objects with characteristic sizes close to the instrumental resolution. We find that the overall contamination by stars misclassified as galaxies is < 5% to b_J = 20.5, as originally estimated for both catalogs. Although our results come from small areas of the sky, they are extracted from two different plates and are based on the comparison with two independent datasets.Comment: 14 pages of text and tables, 8 figures; to be published in the Astronomical Journal; for a single postscript version file see ftp://danw.on.br/outgoing/caretta/caretta.p

Large Structures and Galaxy Evolution in COSMOS at z < 1.1

We present the first identification of large-scale structures (LSS) at z $< 1.1$ in the Cosmic Evolution Survey (COSMOS). The structures are identified from adaptive smoothing of galaxy counts in the pseudo-3d space ($\alpha,\delta$,z) using the COSMOS photometric redshift catalog. The technique is tested on a simulation including galaxies distributed in model clusters and a field galaxy population -- recovering structures on all scales from 1 to 20\arcmin without {\it a priori} assumptions for the structure size or density profile. Our procedure makes {\bf no} {\it a priori} selection on galaxy spectral energy distribution (SED, for example the Red Sequence), enabling an unbiased investigation of environmental effects on galaxy evolution. The COSMOS photometric redshift catalog yields a sample of $1.5\times10^5$ galaxies with redshift accuracy, $\Delta z_{FWHM}/(1+z) \leq 0.1$ at z $< 1.1$ down to I$_{AB} \leq 25$ mag. Using this sample of galaxies, we identify 42 large-scale structures and clusters. abstract truncated for astroph 25 line limit -- see preprintComment: 72 pages with 29 pages of figures, for cosmos apj suppl special issu

Distribution, occurrence and biotoxin composition of the main

En prens

ChaLearn Joint Contest on Multimedia Challenges Beyond Visual Analysis: An overview

This paper provides an overview of the Joint Contest on Multimedia Challenges Beyond Visual Analysis. We organized an academic competition that focused on four problems that require effective processing of multimodal information in order to be solved. Two tracks were devoted to gesture spotting and recognition from RGB-D video, two fundamental problems for human computer interaction. Another track was devoted to a second round of the first impressions challenge of which the goal was to develop methods to recognize personality traits from short video clips. For this second round we adopted a novel collaborative-competitive (i.e., coopetition) setting. The fourth track was dedicated to the problem of video recommendation for improving user experience. The challenge was open for about 45 days, and received outstanding participation: almost 200 participants registered to the contest, and 20 teams sent predictions in the final stage. The main goals of the challenge were fulfilled: the state of the art was advanced considerably in the four tracks, with novel solutions to the proposed problems (mostly relying on deep learning). However, further research is still required. The data of the four tracks will be available to allow researchers to keep making progress in the four tracks

Structure detection in the D1 CFHTLS deep field using accurate photometric redshifts: a benchmark

We investigate structures in the D1 CFHTLS deep field in order to test the method that will be applied to generate homogeneous samples of clusters and groups of galaxies in order to constrain cosmology and detailed physics of groups and clusters. Adaptive kernel technique is applied on galaxy catalogues. This technique needs none of the usual a-priori assumptions (luminosity function, density profile, colour of galaxies) made with other methods. Its main drawback (decrease of efficiency with increasing background) is overcame by the use of narrow slices in photometric redshift space. There are two main concerns in structure detection. One is false detection and the second, the evaluation of the selection function in particular if one wants "complete" samples. We deal here with the first concern using random distributions. For the second, comparison with detailed simulations is foreseen but we use here a pragmatic approach with comparing our results to GalICS simulations to check that our detection number is not totally at odds compared to cosmological simulations. We use XMM-LSS survey and secured VVDS redshifts up to z~1 to check individual detections. We show that our detection method is basically capable to recover (in the regions in common) 100% of the C1 XMM-LSS X-ray detections in the correct redshift range plus several other candidates. Moreover when spectroscopic data are available, we confirm our detections, even those without X-ray data.Comment: 14 pages, 22 additionnal jpeg figures, accepted in A&

Field testing for toxic algae with a microarray: initial results from the MIDTAL project

One of the key tasks in the project MIDTAL (MIcroarrays for the Detection of Toxic ALgae) is to demonstrate the applicability of microarrays to monitor harmful algae across a broad range of ecological niches and toxic species responsible for harmful algal events. Water samples are collected from a series of sites used in national phytoplankton and biotoxin monitoring programmes across Europe. The samples are filtered; the rRNA is extracted, labelled with a fluorescent dye and applied to a microarray chip. The signal intensity from >120 probes previously spotted on the chip is measured and analysed. Preliminary results comparing microarray signal intensities with actual field counts are presented